Nathaniel Ninyio
Position: Postdoctoral Researcher School/office: School of Medical SciencesEmail: nathaniel.ninyio@oru.se
Phone: +46 19 302189
Room: X3119
About Nathaniel Ninyio
Research
Nathaniel’s research interests are in the area of molecular virology and immunology. Although he has previously garnered substantial research experience in bacteriology and drug development, more recently, his research is focused on vaccine development for viral infections such as HIV, hepatitis B and Influenza A. Broadly speaking, his current research is on the use of engineered probiotic bacteria in vaccine development.
Education and Career
Nathaniel holds a Bachelor’s degree in Microbiology from Madonna University, Nigeria (2008). In 2013, he obtained a Master’s degree in Microbial Biotechnology (UCSI University, Malaysia). Nathaniel defended his doctoral thesis in 2020 at Universiti Putra Malaysia where he studied virus-like particle (VLP) vaccine production. Specifically, he developed a chimeric VLP vaccine for hepatitis B and he elucidated the biophysical and immunological properties of this vaccine candidate.
Career-wise, Nathaniel started as a graduate assistant (tutor) at Kaduna State University, Nigeria in 2011. In 2021, he was offered the position of postdoctoral researcher at the School of Medical Sciences, Örebro University.
Publications
Articles in journals
- Ninyio, N. , Schmitt, K. , Sergon, G. , Nilsson, C. , Andersson, S. & Scherbak, N. (2024). Stable expression of HIV-1 MPER extended epitope on the surface of the recombinant probiotic bacteria Escherichia Coli Nissle 1917 using CRISPR/Cas9. Microbial Cell Factories, 23 (1).
- Ninyio, N. , Lian Ho, K. , Yeah Yong, C. , Yee Chee, H. , Hamid, M. , Kian Ong, H. , Razak Mariatulqabtiah, A. & Siang Tan, W. (2021). Chimeric Virus-Like Particles of Prawn Nodavirus Displaying Hepatitis B Virus Immunodominant Region: Biophysical Properties and Cytokine Response. International Journal of Molecular Sciences, 22 (4).
- Ninyio, N. , Lian Ho, K. , Kian Ong, H. , Yeah Yong, C. , Yee Chee, H. , Hamid, M. & Sian Tan, W. (2020). Immunological Analysis of the Hepatitis B Virus “a” Determinant Displayed on Chimeric Virus-Like Particles of Macrobrachium rosenbergii Nodavirus Capsid Protein Produced in Sf9 Cells. Vaccines, 8 (2).
- Ninyio, N. , Bashir Gidado, H. , Yahaya, M. O. Y. , Fadason, T. B. , Bamanga, R. A. B. & Yaki, L. M. Y. (2017). Ethanolic Allium sativum extract down-regulates the pelF gene involved in Pseudomonas aeruginosa biofilm formation. African Journal of Biotechnology, 16 (12), 585-593.
- Tandhyka Gemiarto, A. , Ninyio, N. , Wei Lee, S. , Logis, J. , Fatima, A. , Wei Chiang Chan, E. & Siew Ying Lim, C. (2015). Isoprenyl caffeate, a major compound in manuka propolis, is a quorum-sensing inhibitor in Chromobacterium violaceum. Antonie van Leeuwenhoek. International Journal of General and Molecular Microbiology, 108 (2), 491-504.
Articles, book reviews
- Ninyio, N. , Lian Ho, K. , Rahman Omar, A. , Siang Tan, W. , Iqbal, M. & Razak Mariatulqabtiah, A. (2020). Virus-like Particle Vaccines: A Prospective Panacea Against an Avian Influenza Panzootic. Vaccines, 8 (4).
Articles, reviews/surveys
- Kabantiyok, D. , Ninyio, N. , Shittu, I. , Meseko, C. , Emeto, T. I. & Adegboye, O. A. (2022). Human Respiratory Infections in Nigeria: Influenza and the Emergence of SARS-CoV-2 Pandemic. Vaccines, 10 (9).
Conference papers
- Ninyio, N. , Scherbak, N. & Andersson, S. (2022). Development and analysis of prospective anti-HIV probiotic vaccines. In: 19th Smögen Summer Symposium on Virology Abstracts. Paper presented at 19th Smögen Summer Symposium on Virology, Smögen, August 25-27, 2022. (pp. 40-40). Virus- och Pandemifonden – Swedish Society for Virology.
- Scherbak, N. , Ninyio, N. , Nilsson, C. , Rybicki, E. & Andersson, S. (2022). Production of anti-viral vaccines using probiotic bacteria. In: 19th Smögen Symposium on Virology: Abstracts Viral Immunology and Vaccines II and III. Paper presented at 19th Smögen Symposium on Virology, Smögen, August 25-27, 2022. (pp. 16-16). Virus- och Pandemifonden – Swedish Society for Virology.