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Research projects

Ischemia-reperfusion injury during surgery and trauma - development of methods to reduce organ damage

About this project

Project information

Project status

In progress

Contact

Kristofer Nilsson

Research subject

The project aims to develop and improve methods to reduce ischemia-reperfusion injuries in both the use of resuscitative endovascular balloon occlusion of the aorta (REBOA) and in other ischemic organ injuries related to surgery and to develop strategies to balance vascular occlusion time with the subsequent ischemic injury from a circulatory, metabolic and inflammatory perspective. The project includes animal experimental models with physiological, pharmacological, metabolic and inflammatory measurement methods.

Collaborators

  • Attgeno AB, Stockholm,
  • Professor Claes Frostell, Anestesi och Intensivvård, Kliniska vetenskaper, Danderyds sjukhus, Karolinska Institutet