Postdoctoral researcher in Mathematical/Computational Systems Biology

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Ref nr: ORU 2.1.1- 04000/2020

The School of Medical Sciences is seeking a postdoctoral researcher in Mathematical/Computational Systems Biology for a fixed-term appointment.

Subject area

The position is in Biomedicine.

Background

Inflammation constitutes a critical component of many common diseases, such as cancer, mental illness, autoimmune disease, metabolic diseases, diabetes, and cardiovascular disease. Current research reveals a profound lack of a mechanistic understanding of different forms of inflammation, and how these constitute specific or general interactions with common diseases. The current position is part of a larger project (X-HiDE) aimed at using a systems biology approach to investigate inflammatory mechanisms.

More information can be found at www.oru.se/X-HiDE

The project will build and investigate mathematical and mechanistic models of inflammatory processes on various scales, based on dynamical data produced from in vitro models and connected to large-scale clinical data and OMICs data. The project is transdisciplinary and includes business partners in the Life Science/Pharmaceutical industry. This project is hosted by the Inflammatory Response and Infection Susceptibility Center (iRiSC) at Örebro University, which, together with the Functional Bioinformatics group, will be the main affiliation for the position. Örebro University is one of the most expansive universities in Sweden, and was most recently placed as number 75 when Times Higher Education ranked the young universities in the world, and as number 30 when looking at the citation rate per se.

More information about Örebro University can be found at www.oru.se/english

Duties and responsibilities

The appointment as a postdoctoral researcher is intended to enable persons, who have recently been awarded their doctoral degree, to consolidate and develop primarily their research/artistic skills. The applicant will be responsible for developing and investigating dynamical mathematical models based on experimental data available within X-HiDE relevant for a variety of mechanisms at different scales of inflammation. The applicant will engage in tight discussion for hypothesis development, model specification and adaptation, as well as generation of model predictions in close collaboration with experimentally working biomedical researchers and clinicians. 

Eligibility

Eligible for the appointment as postdoctoral researcher are applicants holding a doctoral degree in physics, computer science, applied statistics or in related subject areas, with close relation to medical or life sciences.

Assessment criteria

General assessment criteria include excellent interpersonal skills, and an ability to collaborate as well as to perform the duties well with high quality and suitability. Particular importance shall be attached to the qualities enabling the candidate to contribute to the future development of both research and education. A demonstrated ability and desire to pursue an academic career is also of importance.

In addition, experience of mathematical and mechanistic modelling techniques is crucial, preferably within systems biology or related areas, where analysis of dynamical models is of importance. The applicant should also have documented experience with data analysis in the (bio)medical fields. Previous research within dynamical mathematical and mechanistic model analysis in the life sciences is preferred. Since the project will be conducted in close collaborations with other professions and non-academic partners, a cooperative mindset is of great importance. The applicant should also be highly organized, able to meet deadlines, have a clear sense of responsibility, and be goal oriented.

The current position constitutes a vital part in establishing a new attractive platform for systems biology, which offers some unique possibilities for the postdoc. The project X-HiDE has already secured long-term and substantial funding - intended to found a Center of Excellence for research in inflammatory mechanisms. The building of a new systems biology group within X-HiDE also consist of new senior staff, and such more senior positions will open up in the future; making X-HiDE an attractive place for a long-term career in the field of mathematical and mechanistic modelling. Most important, X-HiDE has an attractive network of collaboration partners with existing systems biology environments, involving academic partners located at, e.g. Linköping University, Sweden, and at Rostock University, Germany but also major industrial partners, e.g. AstraZeneca in Gothenburg and Wolfram MathCore in Linköping. As part of the project, the position offers the possibility and is encouraged to spend shorter or longer times at any of these sites.

Information

The position is a full-time position for a fixed term of two years, with the possibility of applying for an additional third year. The salary depends on the successful candidate’s qualifications and experience.

For more information, please contact Dr. Robert Kruse +46-19-30 3000, or professors Dirk Repsilber, +46-19-30 1256 or Eva Särndahl +46-19-30 3684.

Örebro University actively pursues an equal work environment and values the qualities that diversity adds to our operations.

Application

The application is made online. Click the button “Apply” to begin the application procedure.

For the application to be complete, the following electronic documents must be included:

  • A covering letter, outlining how you believe you can contribute to the continued development of Örebro University
  • CV with a relevant description of your overall qualifications and experience
  • An account of research/artistic qualifications
  • Copies of relevant course/degree certificates and references verifying eligibility and criteria met
  • Scientific publications for consideration (maximum of 10) (Not only publication list.)

Only documents written in Swedish, English, Norwegian or Danish can be reviewed.

The application deadline is September 1, 2020. We look forward to receiving your application!

We decline any contact with advertisers or recruitment agencies in the recruitment process.

As directed by the National Archives of Sweden (Riksarkivet), Örebro University is required to deposit one file copy of the application documents, excluding publications, for a period of two years after the appointment decision has gained legal force.