Researcher in Mathematical/Computational Systems Biology

Tillsvidareanställning
Heltid
Ansök senast
Ansök

Ref nr: ORU 2.1.1-04521/2021

We are looking for a researcher in Mathematical/Computational Systems Biology for a permanent full-time position at the School of Medical Sciences at Örebro University.

Subject area

The subject area for this position is Biomedicine.

Background

This position is a unique opportunity to become a central collaborator in the establishment of the large and well-funded project X-HiDE (www.oru.se/X-HiDE); aiming at using a systems biology approach to investigate inflammatory mechanisms. We are looking for a researcher (junior or senior), who wants to establish a long-term research platform at Örebro University.

X-HiDE will build and investigate mathematical mechanistic models of inflammatory processes on various scales, based on dynamical data produced from in vitro models and connected to large-scale clinical OMICs data. The focus is on mathematical ODE-based multi-level modeling, with systematic testing of subsystem mechanisms, and assembly of these into larger models to represent overall systems views. Models will then be investigated regarding their role in inflammation seen in common diseases, and towards translating these findings for clinical application, hybrid modeling approaches will be followed.

X-HiDE is hosted by the Inflammatory Response and Infection Susceptibility Center (iRiSC) at Örebro University (www.oru.se/iRiSC), which, together with the Functional Bioinformatics group, will be the main affiliation for the position. X-HiDE is transdisciplinary and includes also academic partners located at Linköping University, Sweden, and at Rostock University, Germany but also major industrial partners, e.g. AstraZeneca in Gothenburg and Wolfram MathCore in Linköping. As part of the project, the position offers the possibility and is encouraged to spend shorter or longer times at these sites.

Duties and responsibilities

Duties and responsibilities involve research, teaching, and collaboration.  We expect the researcher to develop his/her autonomy as a scientist and to acquire further qualifications in terms of both research and teaching skills. The position shall also contribute to the University’s development, and as such be responsible of coordinating the establishment of Systems biology at Örebro University. The University has a strong profile in artificial intelligence (AI) and is looking for further opportunities to expand its multi-disciplinary research, and thus an important part of the position is to collaborate and find links to the AI research at Örebro University. The successful candidate is therefore expected to act as a bridge between the AI research environment and systems biology at X-HIDE, and to find new projects and opportunities between the two environments. The main work of the position involves coordinating the collaboration between X-HiDE’s partners – academic and industrial. Also, one important task is to take initiative for further national and international collaborations and funding.

The applicant will also be involved in the development and investigation of dynamical mathematical models based on experimental data available within X-HiDE; data relevant for a variety of mechanisms at different scales of inflammation. The applicant will engage in in-depth discussions for hypothesis development, model specification and adaptation, as well as generation of model predictions in close collaboration with experimentally working biomedical researchers and clinicians.

The researcher will further develop courses and teach on masters and PhD level.

Qualifications

Those qualified for the appointment as a researcher are applicants, who have obtained a doctoral degree, or a degree from abroad deemed to correspond to a doctoral degree.

Assessment criteria

The position requires good networking and coordinating skills, and we welcome a researcher with an extensive international network. Since the project will be conducted in close collaborations with other professions and non-academic partners, a cooperative mindset is of great importance. Also, personal skills and abilities, such as teamworking, power of initiative, and a drive to move things forward is vital. The applicant should also be highly organized, able to meet deadlines, have a clear sense of responsibility, and be goal oriented. A general basis for assessment is that the applicant can demonstrate the personal qualities required to successfully perform the duties and responsibilities at hand.

Experience of mathematical and mechanistic modeling techniques is crucial, preferably within systems biology or related areas, where analysis of dynamical models is of importance. The applicant should also have documented experience with data analysis in the (bio)medical fields. Previous research within dynamical mathematical and mechanistic model analysis in the life sciences is preferred. Other additional merits include network-based bioinformatics modeling, machine learning, and other related techniques.

The duties require very good communicative skills in English, both in writing and in speech; a request that is mandatory. The long-term goal is to have the researcher developing his or her skills and expertise within research and education to be qualified for a position as senior lecturer. Good communicative skills in Swedish in speech and in writing, at such a level that is necessary for the candidate to be able to perform frequent duties and responsibilities within research, teaching and administration, will then be required.

Information

This is a permanent full-time position. At Örebro University, salary depends on the successful candidate’s qualifications and experience, and positions announced are, where appropriate, subject to a trial period of six months.

For more information about the position, contact Professor Eva Särndahl, Project Manager: +46 19 30 3684, email: This is an email address, Dr. Robert Kruse, Research Manager of X-HiDE: +46 19 6026697, email: This is an email address, or Professor Magnus Johansson, Acting Head of the Department: +46 19 30 2443, email: This is an email address.)

At Örebro University, we expect each member of staff to be open to development and change; take responsibility for their work and performance; demonstrate a keen interest in collaboration and contribute to development; as well as to show respect for others by adopting a constructive and professional approach.

Örebro University actively pursues equal opportunities and gender equality as well as a work environment characterized by openness, trust, and respect. We value the qualities that diversity adds to our operations.

Örebro University is one of the most expansive universities in Sweden, and was most recently placed as number 75 when Times Higher Education ranked the young universities in the world, and as 127th in the world when looking at the citation rate per se: https://www.oru.se/english/about-us/orebro-university-in-rankings/

Application

The application is made online. Click the button “Apply” to begin the application procedure.

For the application to be complete, the following electronic documents must be included:

  • Covering letter, outlining how you believe you can contribute to the continued development of Örebro University
  • CV with a relevant description of your overall qualifications and experience
  • Account of [research/artistic] qualifications and experience
  • Copies of relevant course/degree certificates and references verifying eligibility and criteria met

Only documents written in Swedish, English, Norwegian and Danish can be reviewed.
More information for applicants will be found at out career site:  https://www.oru.se/english/working-at-orebro-university/jobs-and-vacancies/applicants-and-external-experts/

The application deadline is 2021-09-30. We look forward to receiving your application!

We decline any contact with advertisers or recruitment agencies in the recruitment process.

As directed by the National Archives of Sweden (Riksarkivet), we are required to deposit one file copy of the application documents, excluding publications, for a period of two years after the appointment decision has gained legal force.