Annica Gad

Articles in journals

• Hou, S. , Macfarlane, S. C. , Gómez Torijano, A. , Kim, H. R. , Rosier, M. , Dobra, K. , Ottewell, P. D. & Gad, A. (2025). Cancer-Associated Fibroblasts Move and Interact More with Triple-Negative Breast Cancer Cells and Stimulate Their Proliferation in a Hyaluronan-Dependent Manner.  Cells, 14 (21). [BibTeX]
• Hutyra-Gram Ötvös, R. , Krynska, H. , Gudoityte, G. , Skribek, M. , Oniscu, A. , Berkovska, O. , Strauß, K. , Zipprick, J. & et al. (2025). Ex Vivo Drug Sensitivity of Pleural Effusion-Derived Cells from Lung Cancer and Pleural Mesothelioma Patients Is Linked to Clinical Response.  Cancers, 17 (14). [BibTeX]
• Tseng, P. , Sun, W. , Salem, A. , Alaklobie, M. , Macfarlane, S. C. , Gad, A. K. B. , Collins, M. O. & Erdmann, K. S. (2025). Mechanical control of the alternative splicing factor PTBP1 regulates extracellular matrix stiffness induced proliferation and cell spreading.  iScience, 28 (4). [BibTeX]
• Mamalakis, M. , Macfarlane, S. C. , Notley, S. V. , Gad, A. K. B. & Panoutsos, G. (2024). A novel pipeline employing deep multi-attention channels network for the autonomous detection of metastasizing cells through fluorescence microscopy.  Computers in Biology and Medicine, 181. [BibTeX]
• Rosier, M. , Krstulović, A. , Kim, H. R. , Kaur, N. , Enakireru, E. M. , Symmes, D. , Dobra, K. , Chen, R. & et al. (2024). The Vimentin-Targeting Drug ALD-R491 Partially Reverts the Epithelial-to-Mesenchymal Transition and Vimentin Interactome of Lung Cancer Cells.  Cancers, 17 (1). [BibTeX]
• López-Guajardo, A. , Zafar, A. , Al Hennawi, K. , Rossi, V. , Alrwaili, A. , Medcalf, J. D. , Dunning, M. , Nordgren, N. & et al. (2023). Regulation of cellular contractile force, shape and migration of fibroblasts by oncogenes and Histone deacetylase 6.  Frontiers in Molecular Biosciences, 10. [BibTeX]
• Kim, H. R. , Warrington, S. J. , López-Guajardo, A. , Al Hennawi, K. , Cook, S. L. , Griffith, Z. D. J. , Symmes, D. , Zhang, T. & et al. (2022). ALD-R491 regulates vimentin filament stability and solubility, cell contractile force, cell migration speed and directionality.  Frontiers in Cell and Developmental Biology, 10. [BibTeX]
• Shaebani, M. R. , Stankevicins, L. , Vesperini, D. , Urbanska, M. , Flormann, D. A. , Terriac, E. , Gad, A. K. B. , Cheng, F. & et al. (2022). Effects of vimentin on the migration, search efficiency, and mechanical resilience of dendritic cells.  Biophysical Journal, 121 (20), 3950-3961. [BibTeX]
• Tonge, J. J. , Notley, S. V. , Dunning, M. J. , López-Guajardo, A. , Medcalf, J. D. , Heldin, P. , Panoutsos, G. & Gad, A. K. B. (2022). Hyaluronan nanoscale clustering and Hyaluronan synthase 2 expression are linked to the invasion of child fibroblasts and infantile fibrosarcoma in vitro and in vivo.  Research Square. [BibTeX]
• Tonge, J. J. , Notley, S. V. , Dunning, M. J. , López-Guajardo, A. , Medcalf, J. D. , Heldin, P. , Panoutsos, G. & Gad, A. K. B. (2022). Hyaluronan nanoscale clustering and Hyaluronan synthase 2 expression are linked to the invasion of child fibroblasts and infantile fibrosarcoma in vitro and in vivo.  Scientific Reports, 12 (1). [BibTeX]
• Evans, C. A. , Kim, H. R. , Macfarlane, S. C. , Nowicki, P. I. A. , Baltes, C. , Xu, L. , Widengren, J. , Lautenschläger, F. & et al. (2022). Metastasising Fibroblasts Show an HDAC6-Dependent Increase in Migration Speed and Loss of Directionality Linked to Major Changes in the Vimentin Interactome.  International Journal of Molecular Sciences, 23 (4). [BibTeX]
• Flormann, D. A. D. , Schu, M. , Terriac, E. , Thalla, D. , Kainka, L. , Koch, M. , Gad, A. K. B. & Lautenschläger, F. (2021). A novel universal algorithm for filament network tracing and cytoskeleton analysis.  The FASEB Journal, 35 (5). [BibTeX]
• Xu, L. , Braun, L. J. , Rönnlund, D. , Widengren, J. , Aspenström, P. & Gad, A. K. B. (2018). Nanoscale localization of proteins within focal adhesions indicates discrete functional assemblies with selective force‐dependence.  The FEBS Journal, 285 (9), 1635-1652. [BibTeX]
• Alkasalias, T. , Alexeyenko, A. , Hennig, K. , Danielsson, F. , Lebbink, R. J. , Fielden, M. , Turunen, S. P. , Lehti, K. & et al. (2017). RhoA knockout fibroblasts lose tumor-inhibitory capacity in vitro and promote tumor growth in vivo.  Proceedings of the National Academy of Sciences of the United States of America, 114 (8), E1413-E1421. [BibTeX]
• Terriac, E. , Coceano, G. , Mavajian, Z. , Hageman, T. , Christ, A. , Testa, I. , Lautenschläger, F. & Gad, A. K. B. (2017). Vimentin Levels and Serine 71 Phosphorylation in the Control of Cell-Matrix Adhesions, Migration Speed, and Shape of Transformed Human Fibroblasts.  Cells, 6 (1). [BibTeX]
• Fallqvist, B. , Fielden, M. L. , Pettersson, T. , Nordgren, N. , Kroon, M. & Gad, A. K. B. (2016). Experimental and computational assessment of F-actin influence in regulating cellular stiffness and relaxation behaviour of fibroblasts.  Journal of The Mechanical Behavior of Biomedical Materials, 59, 168-184. [BibTeX]
• Xu, L. , Rönnlund, D. , Aspenström, P. , Braun, L. J. , Gad, A. K. B. & Widengren, J. (2016). Resolution, target density and labeling effects in colocalization studies – suppression of false positives by nanoscopy and modified algorithms.  The FEBS Journal, 283 (5), 882-898. [BibTeX]
• Blom, M. , Reis, K. , Nehru, V. , Blom, H. , Gad, A. K. B. & Aspenström, P. (2015). RhoD is a Golgi component with a role in anterograde protein transport from the ER to the plasma membrane.  Experimental Cell Research, 333 (2), 208-219. [BibTeX]
• Rönnlund, D. , Xu, L. , Perols, A. , Gad, A. K. B. , Eriksson Karlström, A. , Auer, G. & Widengren, J. (2014). Multicolor Fluorescence Nanoscopy by Photobleaching: Concept, Verification, and Its Application To Resolve Selective Storage of Proteins in Platelets.  ACS Nano, 8 (5), 4358-4365. [BibTeX]
• Rathje, L. Z. , Nordgren, N. , Pettersson, T. , Rönnlund, D. , Widengren, J. , Aspenström, P. & Gad, A. K. B. (2014). Oncogenes induce a vimentin filament collapse mediated by HDAC6 that is linked to cell stiffness.  Proceedings of the National Academy of Sciences of the United States of America, 111 (4), 1515-1520. [BibTeX]
• Spielmann, T. , Xu, L. , Gad, A. K. B. , Johansson, S. & Widengren, J. (2014). Transient state microscopy probes patterns of altered oxygen consumption in cancer cells.  The FEBS Journal, 281 (5), 1317-1332. [BibTeX]
• Danielsson, F. , Skogs, M. , Huss, M. , Rexhepaj, E. , O’Hurley, G. , Klevebring, D. , Pontén, F. , Gad, A. K. B. & et al. (2013). Majority of differentially expressed genes are down-regulated during malignant transformation in a four-stage model.  Proceedings of the National Academy of Sciences of the United States of America, 110 (17), 6853-6858. [BibTeX]
• Rönnlund, D. , Gad, A. K. B. , Blom, H. , Aspenström, P. & Widengren, J. (2013). Spatial organization of proteins in metastasizing cells.  Cytometry Part A, 83 (9), 855-865. [BibTeX]
• Gad, A. K. B. , Rönnlund, D. , Spaar, A. , Savchenko, A. A. , Petranyi, G. , Blom, H. , Szekely, L. , Widengren, J. & et al. (2012). Rho GTPases link cellular contractile force to the density and distribution of nanoscale adhesions.  The FASEB Journal, 26 (6), 2374-2382. [BibTeX]
• Gad, A. K. B. , Nehru, V. , Ruusala, A. & Aspenström, P. (2012). RhoD regulates cytoskeletal dynamics via the actin nucleation–promoting factor WASp homologue associated with actin Golgi membranes and microtubules.  Molecular Biology of the Cell, 23 (24), 4807-4819. [BibTeX]
• Gad, A. , Lach, S. , Crimaldi, L. & Gimona, M. (2008). Plectin deposition at podosome rings requires myosin contractility.  Cell Motility and the Cytoskeleton, 65 (8), 614-625. [BibTeX]
• Thullberg, M. , Gad, A. , Le Guyader, S. & Strömblad, S. (2007). Oncogenic H-Ras V12 promotes anchorage-independent cytokinesis in human fibroblasts.  Proceedings of the National Academy of Sciences of the United States of America, 104 (51), 20338-20343. [BibTeX]
• Thullberg, M. , Gad, A. , Beeser, A. , Chernoff, J. & Strömblad, S. (2006). The kinase-inhibitory domain of p21-activated kinase 1 (PAK1) inhibits cell cycle progression independent of PAK1 kinase activity.  Oncogene, 26 (12), 1820-1828. [BibTeX]
• Päll, T. , Gad, A. , Kasak, L. , Drews, M. , Strömblad, S. & Kogerman, P. (2004). Recombinant CD44-HABD is a novel and potent direct angiogenesis inhibitor enforcing endothelial cell-specific growth inhibition independently of hyaluronic acid binding.  Oncogene, 23 (47), 7874-7881. [BibTeX]
• Gad, A. , Thullberg, M. , Dannenberg, J. , Riele, H. t. & Strömblad, S. (2004). Retinoblastoma Susceptibility Gene Product (pRb) and p107 Functionally Separate the Requirements for Serum and Anchorage in the Cell Cycle G1-phase.  Journal of Biological Chemistry, 279 (14), 13640-13644. [BibTeX]
• Bakhiet, M. , Tjernlund, A. , Mousa, A. , Gad, A. , Strömblad, S. , Kuziel, W. A. , Seiger, Å. & Andersson, J. (2001). RANTES promotes growth and survival of human first-trimester forebrain astrocytes.  Nature Cell Biology, 3 (2), 150-157. [BibTeX]

Articles, reviews/surveys

• Zipprick, J. , Demir, E. , Krynska, H. , Köprülüoğlu, S. , Strauß, K. , Skribek, M. , Hutyra-Gram Ötvös, R. , Gad, A. K. B. & et al. (2025). Ex-Vivo Drug-Sensitivity Testing to Predict Clinical Response in Non-Small Cell Lung Cancer and Pleural Mesothelioma: A Systematic Review and Narrative Synthesis.  Cancers, 17 (6), 986-986. [BibTeX]
• Rezk, R. , Marín-García, R. & Gad, A. K. B. (2021). The Fibrillar Matrix: Novel Avenues for Breast Cancer Detection and Treatment.  Engineering (Beijing), 7 (10), 1375-1380. [BibTeX]
• Danielsson, F. , Peterson, M. K. , Caldeira Araújo, H. , Lautenschläger, F. & Gad, A. K. B. (2018). Vimentin Diversity in Health and Disease.  Cells, 7 (10). [BibTeX]
• Gad, A. K. B. & Aspenström, P. (2010). Rif proteins take to the RhoD: Rho GTPases at the crossroads of actin dynamics and membrane trafficking.  Cellular Signalling, 22 (2), 183-189. [BibTeX]

Chapters in books

• Gad, A. K. B. , Rönnlund, D. , Widengren, J. & Aspenström, P. (2013). Analysis of Rho GTPase-Induced Localization of Nanoscale Adhesions Using Fluorescence Nanoscopy. In: Lorenza Trabalzini; Saverio Francesco Retta, Ras Signaling: Methods and Protocols (pp. 339-357). . Humana Press. [BibTeX]

Conference papers

• Thullberg, M. , Gad, A. & Strömblad, S. (2007). Oncogenic H-Ras V12 promotes anchorage-independent cytokinesis. In:  European Journal of Cancer Supplements. Elsevier. [BibTeX]