Publications
Lushnikova, A. , Wickbom, A. , Bohr, J. , Kruse, R., Wirén, A. & Hultgren Hörnquist, E. (2025). Increased Colonic Levels of CD8+ Cytotoxic T lymphocyte-Associated Mediators in Patients With Microscopic Colitis. Inflammatory Bowel Diseases, 31 (8), 2231-2243.
Salomon, B., Sudhakar, P., Bergemalm, D., Andersson, E., Grännö, O., Carlson, M., Hedin, C. R. H., Söderholm, J. D., Öhman, L., BIO IBD Consortium, the COLLIBRI Consortium; Lindqvis. C.M., Kruse. R., et al. (2025). Characterization of Inflammatory Bowel Disease Heterogeneity Using Serum Proteomics: A multicenter study. Journal of Crohn's & Colitis, 19 (5).
Scharf MW et al. Acute effects of butyrate on intestinal permeability in patients with irritable bowel syndrome assessed by a novel colonoscopy research model. Gut Microbes. 2025, 17(1):2545414.
A. Alijagic et al. (2025). Nanoplastics are a major driver of toxicity under co-exposure with perfuorooctanesulfonic acid in human intestinal cells. Environmental Chemistry Letters, 1-9.
Parodis I, Lindblom J, Tsoi A, Palazzo L, Blomkvist Sporre K, Enman Y, Nikolopoulos D, Beretta L. Trajectories of disease evolution upon treatment initiation in systemic lupus erythematosus: results from four clinical trials of belimumab. Rheumatology (Oxford). 2025 May 1;64(5):2697-2705. doi: 10.1093/rheumatology/keae575. PMID: 39412507; PMCID: PMC12048076.
Garantziotis P, Beretta L, Lindblom J, Moysidou GS, Nikolopoulos D, Grieshaber-Bouyer R, Hagen M, Bergmann C, Wirsching A, Bozec A; PRECISESADS Clinical Consortium; Schneider M, Barturen G, Bertsias G, Boumpas DT, Alarcón-Riquelme ME, Mackensen A, Schett G, Parodis I. Differential molecular signatures in response to CD19-CAR T cell therapy compared with conventional pharmacotherapy in systemic lupus erythematosus. Ann Rheum Dis. 2025 Jul 22:S0003-4967(25)04187-1. doi: 10.1016/j.ard.2025.06.2132. Epub ahead of print. PMID: 40701862
Lindblom J, Lagutkin D, Sherina N, Idborg H, Beretta L, Borghi MO; PRECISESADS Clinical Consortium; Peyper JM, Barturen G, Jakobsson PJ, Alarcón-Riquelme ME, Nikolopoulos D, Parodis I. Novel IgG and IgA autoantibodies validated in two independent cohorts are associated with disease activity and determine organ manifestations in systemic lupus erythematosus: implications for anti-LIN28A, anti-HMGN5, anti-IRF5, and anti-TGIF1. Ann Rheum Dis. 2025 Jul;84(7):1164-1179. doi: 10.1016/j.ard.2025.04.008. Epub 2025 May 9. PMID: 40348637
Parodis I, Lagutkin D, Lindblom J, Idborg H, Beretta L, Borghi MO; PRECISESADS Clinical Consortium; Peyper JM, Barturen G, Jakobsson PJ, Alarcón-Riquelme ME, Sherina N, Nikolopoulos D. New IgG and IgA autoantibody specificities against DNA-binding and RNA-binding proteins discriminate systemic lupus erythematosus from health and non-lupus autoimmunity-could anti-LIN28A enhance precision in diagnostics? Ann Rheum Dis. 2025 Jul;84(7):1180-1194. doi: 10.1016/j.ard.2025.04.003. Epub 2025 May 14. PMID: 40374430.
TNF Induces Laminin-332-Encoding Genes in Endothelial Cells and Laminin-332 Promotes an Atherogenic Endothelial Phenotype. A Hayderi, MM Zegeye, S Meydan, A Sirsjö, AK Kumawat, LU Ljungberg. International Journal of Molecular Sciences. 25 (16), 8699.
The association of sepsis with level of care among older people presenting to the emergency department – a national register study in Sweden. Fagermalm EA, Smith DR, Montgomery S, Masarrat P, Kurland L.J Infect Public Health. 2025 Dec;18(12):102942. doi: 10.1016/j.jiph.2025.102942. Epub 2025
Alijagic A, Suljevic D, Engwall M, Särndahl E. 3D printing: Balancing innovation for sustainability with emerging environmental and health risks. E. iScience. 2025 Jul 23;28(8):113185. doi: 10.1016/j.isci.2025.113185. eCollection 2025 Aug 15. PMID: 40809003 Free PMC article. Review.
Damir Suljević, Patrik Karlsson, Muhamed Fočak, Maja Mitrašinović Brulić, Jasmina Sulejmanović, Elma Šehović, Eva Särndahl, Magnus Engwall, Andi Alijagic. Microplastics and nanoplastics co-exposure modulates chromium bioaccumulation and physiological responses in rats. Environment International. Volume 198, April 2025.
Herring M, Särndahl E, Kotlyar O, Scherbak N, Engwall M, Karlsson R, Ejdebäck M, Persson A, Alijagic A. Exploring NLRP3-related phenotypic fingerprints in human macrophages using Cell Painting assay. iScience. 2025 Feb 5;28(3):111961. doi: 10.1016/j.isci.2025.111961. eCollection 2025 Mar 21. PMID: 40040812 Free PMC article
Andi Alijagic, Fredric Södergren Seilitz, Anna Bredberg, Aron Hakonen, Maria Larsson, Erica Selin, Viktor Sjöberg, Oleksandr Kotlyar, Nikolai Scherbak, Dirk Repsilber, Anna Kärrman, Thanh Wang, Eva Särndahl, Magnus Engwall. Deciphering the phenotypic, inflammatory, and endocrine disrupting impacts of e-waste plastic-associated chemicals. Environ Res. 2025 Jan 23:269:120929
RSAD2 is abundant in atherosclerotic plaques and promotes interferon-induced CXCR3-chemokines in human smooth muscle cells. A Hayderi, AK Kumawat, VS Shavva, M Dreifaldt, B Sigvant, MH Petri, B Kragsterman, PS Olofsson, A Sirsjö, LU Ljungberg. Sci Rep. 14, 8196 (2024).
Parodis I, Lindblom J, Toro-Domínguez D, Beretta L, Borghi MO, Castillo J, Carnero-Montoro E, Enman Y, Mohan C, Alarcón-Riquelme ME, Barturen G, Nikolopoulos D; PRECISESADS Clinical Consortium. Interferon and B-cell Signatures Inform Precision Medicine in Lupus Nephritis. Kidney Int Rep. 2024 Mar 13;9(6):1817-1835. doi: 10.1016/j.ekir.2024.03.014. PMID: 38899167; PMCID: PMC11184261.
Parodis I, Lindblom J, Barturen G, Ortega-Castro R, Cervera R, Pers JO, Genre F, Hiepe F, Gerosa M, Kovács L, De Langhe E, Piantoni S, Stummvoll G, Vasconcelos C, Vigone B, Witte T; PRECISESADS Clinical Consortium; Alarcón-Riquelme ME, Beretta L. Molecular characterisation of lupus low disease activity state (LLDAS) and DORIS remission by whole-blood transcriptome-based pathways in a pan-European systemic lupus erythematosus cohort. Ann Rheum Dis. 2024 Jun 12;83(7):889-900. doi: 10.1136/ard-2023-224795. PMID: 38373843; PMCID: PMC11187369.
Parodis I, Lindblom J, Levy RA, Zen M, Cetrez N, Gomez A, Oon S, Henning C, Khamashta M, Quasny HA, Chauhan D, Askanase A, van Vollenhoven R, Nikpour M. Attainment of remission and low disease activity after treatment with belimumab in patients with systemic lupus erythematosus: a post-hoc analysis of pooled data from five randomised clinical trials. Lancet Rheumatol. 2024 Aug 26:S2665-9913(24)00162-0. doi: 10.1016/S2665-9913(24)00162-0. PMID: 39208825.
A. Alijagic et al. (2024). Metabolic and phenotypic changes induced by PFAS exposure in two human hepatocyte cell models. Environment International, 190, 108820.
J. Le Du-Carrée… A. Alijagic et al. (2024). Cocktail effects of tire wear particles leachates on diverse biological models: a multilevel analysis. Journal of Hazardous Materials, 134401.
Salihovic et al. Identification and validation of a blood- based diagnostic lipidomic signature of pediatric inflammatory bowel disease. Nat Commun. 2024;15(1): 4567. doi: 10.1038/s41467-024-48763-7.
Zhao et al. Prognostic subgroups of chronic pain patients using latent variable mixture modeling within a supervised machine learning framework. Sci Rep. 2024, May 31;14(1):12543. doi: 10.1038/s41598-024-62542-w.
Salihovic, S., Nyström, N., Mathisen, C. B., Kruse, R., Olbjørn, C., Andersen, S., Noble, A. J., Dorn-Rasmussen, M. & et al. (2024). Identification and validation of a blood- based diagnostic lipidomic signature of pediatric inflammatory bowel disease. Nature Communications, 15 (1).
Östling, H., Lodefalk, M., Bergman, L., Zaigham, M., Andersson, O., Carlsson, Y., Veje, M., Wikström, A., Domellöf. M., Sengpiel. V., Backman. H., Kruse. R. (2024). Inflammatory and cardiovascular markers in placenta following SARS-CoV-2 infection during pregnancy: A Swedish prospective cohort study. Placenta, 158, 78-88.
Anna Niarakis, Reinhard Laubenbacher, Gary An,..Niloofar Nikaein..et al. Immune digital twins for complex human pathologies: applications, limitations, and challenges. NPJ Syst Biol Appl. 2024 Nov 30;10(1):141.
Salihovic, S., Eklund, D., Kruse, R. et al. Exploring the circulating metabolome of sepsis: metabolomic and lipidomic profiles sampled in the ambulance. Metabolomics 20, 111 (2024).
Herring M, Persson A, Potter R, Karlsson R, Särndahl E, Ejdebäck M: Exposing kinetic disparities between inflammasome readouts using time-resolved analysis. Heliyon, 2024, June 10;11.
Persson A, Koivula T, Jacobsson S, Stenmark B: Diverse proinflammatory response in pharyngeal epithelial cells upon interaction with Neisseria meningitidis carriage and invasive isolates. BMC Infect. Dis., 2024, March 24(286).
Andi Alijagic, Damir Suljević, Muhamed Fočak, Jasmina Sulejmanović, Elma Šehović, Eva Särndahl, Magnus Engwall. The triple exposure nexus of microplastic particles, plastic-associated chemicals, and environmental pollutants from a human health perspective. Environment International. 10 May 2024. doi.org/10.1016/j.envint.2024.108736
Design of a national patient-centered clinical pathway for sepsis in Sweden. Strålin K, Linder A, Brink M, Benjaminsson-Nyberg P, Svefors J, Bengtsson-Toni M, Abelson C, Offenbartl K, Björkqvist K, Rosenqvist M, Rönnkvist A, Svärd-Backlund J, Wallgren K, Tydén J, Wallgren U, Vicente V, Cajander S, Lipcsey M, Nauclér P, Kurland L. Infect Dis (Lond) 2023 Oct;55(10):716-724. doi: 10.1080/23744235.2023.2234033
Predicting sepsis using a combination of clinical information and molecular markers of immune responses sampled in the ambulance. Tuerxun K, Eklund D, Wallgren U, Dannenberg K, Repsilber D, Kruse R, Särndahl E, Kurland L.Sci Rep. 2023 Sep 10;13(1):14917. doi: 10.1038/s41598-023-42081-6.
Soluble LDL-receptor is induced by TNF-α and inhibits hepatocytic clearance of LDL-cholesterol. MM Zegeye, SS Nakka, JSO Andersson, S Söderberg, LU Ljungberg, AK Kumawat, A Sirsjö. J Mol Med. 2023 Dec;101(12):1615-1626.
Interleukin-6 trans-signaling induced laminin switch contributes to reduced trans-endothelial migration of granulocytic cells. MM Zegeye, L Matic, M Lengquist, A Hayderi, M, Grenegård, U Hedin, A Sirsjö, LU Ljungberg*, Ashok K Kumawat*. Atherosclerosis 2023, *indicates shared last authorship.
Lindblom J, Toro-Domínguez D, Carnero-Montoro E, Beretta L, Borghi MO, Castillo J, Enman Y; PRECISESADS Clinical Consortium; Mohan C, Alarcón-Riquelme ME, Barturen G, Parodis I. Distinct gene dysregulation patterns herald precision medicine potentiality in systemic lupus erythematosus. J Autoimmun. 2023 Apr;136:103025. doi: 10.1016/j.jaut.2023.103025. Epub 2023 Mar 28. Erratum in: J Autoimmun. 2023 Nov;140:103052. doi: 10.1016/j.jaut.2023.103052. PMID: 36996699.
Lindblom J, Beretta L, Borghi MO; PRECISESADS Clinical Consortium; Alarcón-Riquelme ME, Parodis I. Serum profiling identifies CCL8, CXCL13, and IL-1RA as markers of active disease in patients with systemic lupus erythematosus. Front Immunol. 2023 Nov 30;14:1257085. doi: 10.3389/fimmu.2023.1257085. PMID: 38098483; PMCID: PMC10720584.
Mathematical models disentangle the role of IL-10 feedbacks in human monocytes upon proinflammatory activation. PMID: 37660912.
Dermal exposure to cobalt studied in vitro in keratinocytes – effects of cobalt exposure on inflammasome activated cytokines, and mRNA response. PMID: 34496682.
Neisseria meningitidis-induced caspase-1 activation in human innate immune cells is LOS-dependent. PMID: 31198794.
Activation of the NLRP3 inflammasome pathway by uropathogenic Escherichia coli is virulence factor-dependent and influences colonization of bladder epithelial cells. PMID: 29662840.
Alijagic A, Scherbak N, Kotlyar O, Karlsson P, Wang X, Odnevall I, et al. A Novel Nanosafety Approach Using Cell Painting, Metabolomics, and Lipidomics Captures the Cellular and Molecular Phenotypes Induced by the Unintentionally Formed Metal-Based (Nano)Particles. Cells. 2023;12(2).
Nikaein et al. Mathematical models disentangle the role of IL-10 feedbacks in human monocytes upon proinflammatory activation. J Biol Chem. 2023, 299(10): 105205.
Alijagic et al. A Novel Nanosafety Approach Using Cell Painting, Metabolomics, and Lipidomics Captures the Cellular and Molecular Phenotypes Induced by the Unintentionally Formed Metal-Based (Nano)Particles. Cells. 2023, 12(2): 281.
Scherbak, N. N., Kruse, R., Nyström, T. & Jendle, J. (2023). Glimepiride Compared to Liraglutide Increases Plasma Levels of miR-206, miR-182-5p, and miR-766-3p in Type 2 Diabetes Mellitus: A Randomized Controlled Trial. Diabetes & metabolism journal, 47 (5), 668-681.
Nikaein, N., Tuerxun, K., Cedersund, G., Eklund, D., Kruse, R., Särndahl, E., Nånberg, E., Thonig, A. & et al. (2023). Mathematical models disentangle the role of IL-10 feedbacks in human monocytes upon proinflammatory activation. Journal of Biological Chemistry, 299 (10).
Chelslín, F., Lodefalk, M. & Kruse, R. (2023). Smoking during pregnancy is associated with the placental proteome. Reproductive Toxicology, 119.
Andi Alijagic, Eva Särndahl. Can evolutionary immunology decode micro and nanoplastic challenges? Front. Immunol. Volume 15 - 2024 | doi: 10.3389/fimmu.2024.1404360
Alijagic A, Hedbrant A, Persson A, Larsson M, Engwall M, Särndahl E: NLRP3 inflammasome as a sensor of micro- and nanoplastics immunotoxicity. Front. Immunol., 2023. April 18;14.
Hedbrant A, Engström C, Andersson L, Eklund D, Westberg H, Persson A, Särndahl E: Occupational quartz and particle exposure affect systemic levels of inflammatory markers related to inflammasome activation and cardiovascular disease. Environ. Health, 2023 March 13;22(1):25
Andi Alijagic, Oleksandr Kotlyar, Maria Larsson, Samira Salihovic, Alexander Hedbrant, Ulrika Eriksson, Patrik Karlsson, Alexander Persson, Nikolai Scherbak, Kim Färnlund, Magnus Engwall, Eva Särndahl. Immunotoxic, genotoxic, and endocrine disrupting impacts of polyamide microplastic particles and chemicals. Environ Int 2023 Dec 29:183:108412, doi: 10.1016/j.envint.2023.108412
Andi Alijagic, Xuying Wang, Naga Vera Srikanth Vallabani, Pelle Melin, Eva Särndahl, Hanna L, Karlsson, Inger Odnevall. Characteristics and health risks of the inhalable fraction of metal additive manufacturing powders. Nano Select, doi.org/10.1002/nano.202300188
Flagship publication: Marcus Krantz, Daniel Eklund, Eva Särndahl, Alexander Hedbrant; X-HiDE Consortium. A detailed molecular network map and model of the NLRP3 inflammasome. Front. Immunol., 15 November 2023. doi .org/10.3389/fimmu.2023.1233680
Flagship publication: Niloofar Nikaein, Kedeye Tuerxun, Gunnar Cedersund, Daniel Eklund, Robert Kruse, Eva Särndahl, Eewa Nånberg, Antje Thonig, Dirk Repsilber, Alexander Persson, Elin Nyman; X-HiDE Consortium. Mathematical models disentangle the role of IL-10 feedbacks in human monocytes upon proinflammatory activation. J Biol Chem. 2023 Sep 1;105205. doi: 10.1016/j.jbc.2023.105205. Online ahead of print.
Kedeye Tuerxun, Daniel Eklund, Ulrika Wallgren, Katharina Dannenberg, Dirk Repsilber , Robert Kruse, Eva Särndahl, Lisa Kurland. Predicting sepsis using a combination of clinical information and molecular immune markers sampled in the ambulance. Sci Rep. 2023 Sep 10;13(1):14917. doi: 10.1038/s41598-023-42081-6.
Lena Andersson, Alexander Hedbrant, Ing-Liss Bryngelsson, Per Vihlborg, Eva Särndahl, Håkan Westberg. Silica exposure and cardiovascular, cerebrovascular, and respiratory morbidity in a cohort of male Swedish iron foundry workers. J Occup Environ Med. 2023 Jun 12.
doi: 10.1097/JOM.0000000000002890. Online ahead of print.
William Lövfors, Rasmus Magnusson, Cecilia Jönsson, Mika Gustafsson, Charlotta S. Olofsson, Gunnar Cedersund, Elin Nyman. A comprehensive mechanistic model of adipocyte signaling with layers of confidence. NPJ Syst Biol Appl . 2023 Jun 7;9(1):24.
doi: 10.1038/s41540-023-00282-9.
Hylén U, Särndahl E, Bejerot S, Humble MB, Hyötyläinen T, Salihovic S, Eklund D.
Alterations in inflammasome-related immunometabolites in individuals with severe psychiatric disorders. BMC Psychiatry (2023) 23:268 https://doi.org/10.1186/s12888-023-04784-y
Alijagic A, Hedbrant A, Perssopn A, Larsson M, Engwall M, Särndahl E. NLRP3 inflammasome as a sensor of micro- and nanoplastics immunotoxicity. Front. Immunol., 18 April 2023, Sec. Molecular Innate Immunity Volume 14 - 2023 | https://doi.org/10.3389/fimmu.2023.1178434
Hedbrant A, Engström C, Andersson L, Eklund D, Westberg H, Persson A, Särndahl E.
Occupational quartz and particle exposure affect systemic levels of inflammatory markers related to inflammasome activation and cardiovascular disease.
Environ Health. 2023. doi: 10.1186/s12940-023-00980-1.
Flagship publication: Tuerxun K, Midtbö K, Särndahl E, Vorontsov E, Karlsson R, Persson A, Kruse R, Eklund D; X-HiDE Consortium. Cytokine responses to LPS in reprogrammed monocytes are associated with the transcription factor PU.1. J Leukoc Biol. 2022 Oct;112(4):679-692. doi: 10.1002/JLB.3A0421-216R. Epub 2022 Mar 13. PMID: 35285058
Association between variables measured in the ambulance and in-hospital mortality among adult patients with and without infection: a prospective cohort study. Wallgren UM, Järnbert-Pettersson H, Sjölin J, Kurland L. BMC Emerg Med 2022 Nov 23;22(1):185. doi: 10.1186/s12873-022-00746-x
Presentation of the septic patient to the emergency department with respect to age and sex – a retrospective cross-sectional study. Larsson EA, Wallgren UM, Su A, Short J, Kurland L. BMC Emerg Med 2022 Dec 14;22(1):205. doi: 10.1186/s12873-022-00759-6
Pleiotropic, Unique and Shared Responses Elicited by IL-6 Family Cytokines in Human Vascular Endothelial Cells. Madelene Lindkvist, Mulugeta M Zegeye, Magnus Grenegård, Liza U Ljungberg. Int J Mol Sci. 2022, 27; 23(3): 1448.
Inhibition of IL17A Using an Affibody Molecule Attenuates Inflammation in ApoE-Deficient Mice. AK Kumawat, MM Zegeye, G Paramel, R Baumgartner, A Gisterå, O Amegavie, S Hellberg, H Jin, AS Caravaca, LÅ Söderström, L Gudmundsdotter, FY Frejd, LU Ljungberg, PS Olofsson, DFJ Ketelhuth, A Sirsjö. Front Cardiovasc Med. 2022; 24; 9: 831039.
Hedbrant A, Persson I, Erlandsson A, Wijkander J. Green. Black and Rooibos Tea Inhibit Prostaglandin E2 Formation in Human Monocytes by Inhibiting Expression of Enzymes in the Prostaglandin E2 Pathway. Molecules. 2022;27(2).
Alijagic et al. (2023). A novel nanosafety approach using Cell Painting, metabolomics, and lipidomics captures cellular and molecular phenotypes induced by unintentionally formed metal-based (nano)particles. Cells 12, 281.
Fioretos et al. Implementing precision medicine in a regionally organized healthcare system in Sweden. Nat Med. 2022, 28(10): 1980-1982.
Östling, H., Lodefalk, M., Backman, H. & Kruse, R. (2022). Global microRNA and protein expression in human term placenta. Frontiers in Medicine, 9.
Persson, K., Petersson, U., Johansson, C., Demirel, I. & Kruse, R. (2022). Transcriptional alterations in bladder epithelial cells in response to infection with different morphological states of uropathogenic Escherichia coli. Scientific Reports, 12 (1).
Tuerxun K, Midtbö K, Särndahl E, Vorontsov E, Karlsson R, Persson A, Kruse R, Eklund D: Cytokine responses to LPS in reprogrammed monocytes are associated with the transcription factor PU.1. J. Leuk. Biol., 2022, October 112(4):679-692.
Predicting mortality among septic patients presenting to the emergency department – a cross sectional analysis using machine learning. Karlsson A, Stassen W, Loufi A, Wallgren U, Larsson E, Kurland L. BMC Emerg Med. 2021 Jul 12;21(1):84. doi: 10.1186/s12873-021-00475-7
Performance of NEWS2, RETTS, clinical judgment and the Predict Sepsis screening tools with respect to identification of sepsis among ambulance patients with suspected infection : a prospective cohort study. Ulrika Margareta Wallgren; Jan Sjölin; Hans Järnbert-Pettersson; Lisa Kurland
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2021 Sep 30;29(1):144. doi: 10.1186/s13049-021-00958-3.
Keywords reflecting sepsis presentation based on mode of emergency department arrival: a retrospective cross-sectional study. Wallgren UM, Larsson E, Su A, Short J, Järnbert-Pettersson H, Kurland L. Int J Emerg Med. 2021 Dec 20;14(1):78. doi: 10.1186/s12245-021-00396-z.PMID: 34930114
IL-6 as a Mediator of the Association Between Traditional Risk Factors and Future Myocardial Infarction: A Nested Case-Control Study. MM Zegeye, JSO Andersson, P Wennberg, D Repsilber, A Sirsjö, Liza U Ljungberg. Arteriosclerosis, Thrombosis, and Vascular Biology. 2021; 41 (4), 1570-1579.
Andersson L, Hedbrant A, Persson A, Bryngelsson IL, Sjögren B, Stockfelt L, et al. Inflammatory and coagulatory markers and exposure to different size fractions of particle mass, number and surface area air concentrations in the Swedish hard metal industry, in particular to cobalt. Biomarkers. 2021:1-38.
Hylén U, McGlinchey A, Eklund D, et al. Potential Transdiagnostic Lipid Mediators of Inflammatory Activity in Individuals With Serious Mental Illness. Front Psychiatry. 2021; 12:778325
Zegeye et al. IL-6 as a Mediator of the Association Between Traditional Risk Factors and Future Myocardial Infarction: A Nested Case-Control Study. Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1570-1579.
Hedbrant A, Eklund D, Andersson A, Bryngelsson I-L, Persson A, Westberg H, Särndahl E: Effects on white blood cell counts and the NLRP3 inflammasome due to dust and cobalt exposure in the hard metal industry. Biomarkers, 2021, 27(1):60-70.
The predictive value of variables measurable in the ambulance and the development of the Predict Sepsis screening tools: a prospective cohort study. Wallgren UM, Sjölin J, Järnbert-Pettersson H, Kurland L. Scand J Trauma Resusc Emerg Med. 2020 Jun 25;28(1):59. doi: 10.1186/s13049-020-00745-6.
IL-6 trans-signaling impairs sprouting angiogenesis by inhibiting migration, proliferation and tube formation of human endothelial cells. MM Zegeye, B Andersson, A Sirsjö, LU Ljungberg. Cells. 2020; 9: 1414.
Global transcriptional profiling reveals novel autocrine functions of interleukin-6 in human vascular endothelial cells. LU Ljungberg, MM Zegeye, C Kardeby, K Fälker, D Repsilber, A Sirsjö. Mediators of Inflammation. Vol 2020, Article ID 4623107.
Parodis I, Adamichou C, Aydin S, Gomez A, Demoulin N, Weinmann-Menke J, Houssiau FA, Tamirou F. Per-protocol repeat kidney biopsy portends relapse and long-term outcome in incident cases of proliferative lupus nephritis. Rheumatology (Oxford). 2020 Nov 1;59(11):3424-3434. doi: 10.1093/rheumatology/keaa129. PMID: 32353879.
Hedbrant A, Andersson L, Bryngelsson I-L, Eklund D, Westberg H, Särndahl E, et al. Quartz Dust Exposure Affects NLRP3 Inflammasome Activation and Plasma Levels of IL-18 and IL-1Ra in Iron Foundry Workers. Mediators of inflammation. 2020;2020:10.
Nyman E, Lindh M, Eklund D, et al. Mechanisms of a Sustained Anti-inflammatory Drug Response in Alveolar Macrophages Unraveled with Mathematical Modeling. CPT Pharmacometrics Syst Pharmacol. 2020; 9(12):707–717
Hylén U±, Eklund D±, et al. Increased inflammasome activity in markedly ill psychiatric patients: An explorative study. J Neuroimmunol. 2020; 339:577119
Chavan et al. Predicting Chemical-Induced Liver Toxicity Using High-Content Imaging Phenotypes and Chemical Descriptors: A Random Forest Approach. Chem Res Toxicol. 2020, 33(9): 2261-2275.
Serhan et al. The Atlas of Inflammation Resolution (AIR). Mol Aspects Med. 2020, 74: 100894.
Nyman E, Lindh M, Lövfors W, Simonsson C, Persson A, Eklund D, Bäckström E, Fridén M, Cedersund G: Mechanisms of a sustained anti-inflammatory drug response in alveolar macrophages unraveled with mathematical modelling. CPT Pharmacometrics. Syst. Pharmacol. 2020, 9(12.
Midtbö K, Eklund D, Särndahl E, Persson A: Molecularly distinct NLRP3 inducers mediate diverse ratios of Interleukin-1β and Interleukin-18 from human monocytes. Med. Infl. 2020, October 22.