Agenda and registration to X-HiDE Phase 2 Kick-Off Conference 22-23 September 2025

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Location: Örebro University, X-Huset, Tidefeldtsalen and X2501

Day 1 – Monday 22 September

11.00 - 11.30
Session 1: Here we are and here we go!

  • Welcome and Knowledge transfer - across diseases and within inflammatory phenotypes. (ORU)
  • A decade of Infla-Med: Bridging fundamental insights and translational impact in chronic inflammation. (Infla-Med)
  • Inflammatory phenotypes in cancer development, progression and treatment. (Sprint Bioscience)

11.30 - 13.00
Session 2: Sepsis – a model disease for dysregulated inflammation

  • Sepsis-what is the challenge? (ORU)
  • Dysregulated host (immune) responses (ORU)
  • Immune molecular markers in Predict Sepsis (ORU)
  • Metabolomic signatures of sepsis (ORU)
  • Interleukin-6 signalling components as predictors for sepsis (ORU)

13.00 - 14.00

Lunch at the exhibition

14.00 - 15.30
Session 3: Fingerprinting inflammation in lung disease

  • Introduction and current projects (ORU)
  • Models focus on lungs (Mattek)
  • Products and examples of lung cell exposure and inflammation (Vitrocell)
  • Volatomics (Infla-Med)
  • New Postdoc and project (ORU)

15.30 - 16.15

Coffee break at the exhibition

16.15 - 17.45
Session 4: CVD as a model disease for low-grade inflammation

  • The Hidden Players in Advanced Atherosclerosis: Histopathological Insights into Mast Cell-Mediated Plaque Instability (Infla-Med)
  • Immunometabolic regulation of vascular cells: interferon-γ-altered glutamine metabolism and its implications for atherosclerosis (ORU)
  • Predictive Role of Circulating N-Glycans in Incident CVD(Genos)

19.00 –

Dinner

Day 2 – Tuesday 23 September

8.30 – 10.00
Session 5: From smouldering to flaring – inflammation in lupus and autoimmunity

  • Systemic lupus erythematosus as a model disease in X-HiDE (ORU)
  • CAR-NK cell therapy – from cancer to autoimmunity (Glycostem)
  • The Role of IgG Glycosylation in Autoimmunity (Genos)
  • The vision of molecular reclassification of immune-mediated diseases (ORU)

10.00 – 10.45

Coffee break at the exhibition

10.45 – 12.10
Session 6: Cross-Disease Perspectives on Decoding Inflammation: 
Possibilities, Cohorts, Challenges, and Insights 

  • Knowledge gained and knowledge to be gained by comparing inflammation in different diseases (ORU)
  • The X-HiDE Cohorts; Sepsis, SLE and CVD (ORU)
  • The X-HiDE Model Cohort (ORU)
  • Model Disease cohorts; characteristics and demographics (ORU)
  • Selection of subjects and samples (ORU)
  • Possibilities to characterize shared and unique patterns with:  
  • Proteomic techniques (Somalogic/ StandardBio)
  • Biostatistics and Bioinformatic techniques (ORU)
  • How about difficulties connected to cohort/handling-specific variations (ORU)

12.15 -

Lunch at the exhibition

End of Conference

 

Registration to X-HiDE conference 22-23 September 2025

Registration to X-HiDE conference