Greta Nilén
Position: Doctoral Student School/office: School of Science and TechnologyEmail: greta.nilen@oru.se
Phone: +46 19 301471
Room: B3105
About Greta Nilén
Since August 2017 I am doing my PhD research on mixture effects of environmental chemicals. The limited knowledge of risks associated with mixture toxicity is the starting point for this project that aims to investigate the toxic responses of mixtures of pollutants and integrate those results into risk assessment. In addition, the project aims to fill crucial gaps in the knowledge regarding molecular and mechanism-specific effects of mixture toxicity. To generate a better understanding of toxicant interactions, I am using an in vivo test system and techniques like metabolomics and qPCR.
Research groups
Publications
Articles in journals
- Nilén, G. , Larsson, M. , Hyötyläinen, T. & Keiter, S. (2024). A complex mixture of polycyclic aromatic compounds causes embryotoxic, behavioral, and molecular effects in zebrafish larvae (Danio rerio), and in vitro bioassays. Science of the Total Environment, 906.
- Nilén, G. , Obamwonyi, O. S. , Liem-Nguyen, V. , Engwall, M. , Larsson, M. & Keiter, S. (2022). Observed and predicted embryotoxic and teratogenic effects of organic and inorganic environmental pollutants and their mixtures in zebrafish (Danio rerio). Aquatic Toxicology, 248.
Articles, reviews/surveys
- Legradi, J. B. , Di Paolo, C. , Kraak, M. H. S. , van der Geest, H. G. , Schymanski, E. L. , Williams, A. J. , Dingemans, M. M. L. , Massei, R. & et al. (2018). An ecotoxicological view on neurotoxicity assessment. Environmental Sciences Europe, 30.
Doctoral theses, comprehensive summaries
- Nilén, G. (2023). Molecular and phenotypical toxicological effects of environmental pollutants and their mixtures: A mechanistic approach. (Doctoral dissertation). (Comprehensive summary) Örebro: Örebro University.
Manuscripts
- Nilén, G. , Sunder, S. , Hyötyläinen, T. , Scherbak, N. & Keiter, S. A binary, ternary, and quaternary mixture of PFOS, B[a]P, PCB126, and Arsenic alters behavior, gene expression, and lipid content in zebrafish larvae (Danio rerio).
- Nilén, G. , Ounoughi, A. , Scholz, S. , Keiter, S. H. & Scherbak, N. Measurements of phenotypical effects caused by priority pollutants using a refined high-content screening approach.