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Johan Jendle

Title: Professor School/office: School of Medical Sciences

Email:

Phone: +46 19 301097

Room: C1311

Johan Jendle

Research Subject

Research environments

About Johan Jendle

Johan Jendle, MD, PhD, is a professor at the institute of Medical Sciences, University Hospital Örebro, Sweden. He is also Director for the Diabetes Endocrinology and Metabolism Research 'Center.

Johan Jendle received his medical degree from the University of Linköping, Sweden. His did his postgraduate training in Linköping University Hospital and has specialised in Endocrinology, Diabetology as well as in Internal Medicine. He is also a Certified International Diving Physician (EDTC/ECHM approved).

Research
Prof Jendles main research focus lies within the field of diabetes.  Projects on physical activiy and diabetes has led to dissertations as well as international guidelines. Ongoing projects aim to produce guidelines for athletes with type 1 diabetes in order to optimize both glucose control as well as performance.

Other research areas of interest are glucose lowering drugs (SGLT-2 inhibitors and GLP-1 Receptor Analogues), smart insulin pumps with a cloosed loop function, as well as new continuous monitoring systems (CGM and others).

Prof Jendle is also engeged in research on health economy and diabetes,  screening of diabetic retinophathy and treatment options for obesity.

Prof Jendle has been principal investigator for numerous clinical trials regarding both type 1 and type 2 diabetes. He has authored or co-authored more than 100 papers published in peer-reviewed journals. He is also a regular reviewer and invited speaker at local, national and international scientific meetings.

Techning
Johan Jendle give lectures and is responsible for the examination at advanced level at the medical school at Örebro University. He is also responsible for a national course in diabetes technology (insulin pumps, glucose sensors). Furthermore he also gives lectures for diabetic nurses, general practitioners and specialist in endocrinology and diabetology. He is also responsable for the examination of Swedisch physicians during their intership.

Collaboration and assignments

  • Member of the faculty board of Medicine and Health at Örebro University.
  • Member of the National Board for Internship doctors.
  • Member of the Vice Chancellors Research Counsel at Örebro University.
  • Member of the steeering group at the medical department of Örebro University. Hospital with the responsability of research and development.
  • Specialization Coordinator for the Faculty of Medicine and Health.
  • Chair of the committy evaluation senior lecturers for the Faculty of Medicine and Health.

CV Johan Jendle

Research Projects

Research Teams

Publications

Publications

Articles in journals |  Articles, reviews/surveys |  Chapters in books |  Conference papers | 

Articles in journals

Jendle, J. & Adolfsson, P. (2019). Continuous Glucose Monitoring Diving and Diabetes: An Update of the Swedish Recommendations. Journal of Diabetes Science and Technology.
Jendle, J. , Pöhlmann, J. , de Portu, S. , Smith-Palmer, J. & Roze, S. (2019). Cost-Effectiveness Analysis of the MiniMed 670G Hybrid Closed-Loop System Versus Continuous Subcutaneous Insulin Infusion for Treatment of Type 1 Diabetes. Diabetes Technology & Therapeutics, 21 (3), 110-118.
Jendle, J. , Edelman, S. , Dandona, P. , Mathieu, C. , Thoren, F. A. , Scheerer, M. F. , Xu, J. & Langkilde, A. M. (2019). EFFECT OF ADDING DAPAGLIFLOZIN AS AN ADJUNCT TO INSULIN ON URINARY ALBUMIN-TO-CREATININE RATIO OVER 52 WEEKS IN ADULTS WITH TYPE 1 DIABETES. Diabetes Technology & Therapeutics, 21 (Suppl. 1), A136-A137.
Jendle, J. , Birkenfeld, A. L. , Polonsky, W. H. , Silver, R. , Uusinarkaus, K. , Hansen, T. , Håkan-Bloch, J. , Tadayon, S. & et al. (2019). Improved treatment satisfaction in patients with type 2 diabetes treated with once-weekly semaglutide in the SUSTAIN trials. Diabetes, obesity and metabolism.
Fadini, G. P. , Feher, M. , Hansen, T. K. , de Valk, H. W. , Koefoed, M. M. , Wolden, M. , Zimmermann, E. & Jendle, J. (2019). Reduced rates of overall hypoglycaemia in patients with Type 1 diabetes after switching to insulin degludec: A European, multinational, multicentre, prospective, observational study (ReFLeCT). Diabetic Medicine, 36 (Suppl. 1), 60-60.
Fadini, G. P. , Feher, M. , Hansen, T. K. , de Valk, H. W. , Koefoed, M. M. , Wolden, M. , Zimmermann, E. & Jendle, J. (2019). Reduced rates of overall hypoglycaemia in patients with Type 2 diabetes after switching to insulin degludec: A European, multinational, multicentre, prospective, observational study (ReFLeCT). Diabetic Medicine, 36 (Suppl. 1), 60-60.
Fadini, G. P. , Feher, M. , Hansen, T. K. , de Valk, H. W. , Koefoed, M. M. , Wolden, M. , Zimmerman, E. & Jendle, J. (2019). Switching to Degludec from Other Basal Insulins is Associated with Reduced Hypoglycemia Rates: a Prospective Study. Journal of Clinical Endocrinology and Metabolism.
Jendle, J. , Sandberg, A. , Buchs, S. , Swinburn, P. , Hadi, M. & Levin, L. Å. (2018). A utility valuation study assessing the impact of postprandial glucose control on quality of life of individuals with type 1 or type 2 diabetes. Journal of Patient-Reported Outcomes, 2 (20).
Sharif, A. , Jendle, J. & Hellgren, K. J. (2018). Compliance to Screening of Diabetic Retinopathy with 18 to 36 Months Interval. European Journal of Ophthalmology, 28 (Suppl. 1), 9-9.
Jendle, J. , Fang, X. , Cao, Y. , Bojö, L. , Nilsson, B. , Hedberg, F. , Santos-Pardo, I. & Nyström, T. (2018). Effects on repetitive 24-hour ambulatory blood pressure in type 2 diabetic subjects randomized to liraglutide or glimepiride treatment both in combination with metformin: A randomized open parallel-group study. Journal of the American Society of Hypertension : JASH, 12 (5), 346-355.
Nyström, T. , Santos-Pardo, I. , Hedberg, F. , Wardell, J. , Witt, N. , Cao, Y. , Bojö, L. , Nilsson, B. & et al. (2018). Effects on Subclinical Heart Failure in Type 2 Diabetic Subjects on Liraglutide Treatment vs. Glimepiride Both in Combination with Metformin: A Randomized Open Parallel-Group Study (vol 8, 325, 2017). Frontiers in Endocrinology, 9.
Jendle, J. & Heinemann, L. (2018). Real-Time Continuous Glucose Monitoring Usage in Pilots with Diabetes: An Option to Improve Safety. Diabetes Technology & Therapeutics, 20 (7), 453-454.
Jendle, J. , Birkenfeld, A. L. , Silver, R. , Uusinarkaus, K. , Højbjerre, L. , Thomsen, H. F. & Davies, M. (2017). Effect of Gastrointestinal Adverse Events on Treatment Satisfaction in Semaglutide Treatment of Type 2 Diabetes. Value in Health, 20 (9), A484-A484.
Ridderstrale, M. , Evans, L. M. , Jensen, H. H. , Bøgelund, M. , Jensen, M. M. , Ericsson, Å. & Jendle, J. (2016). Estimating the impact of changes in HbA(1c), body weight and insulin injection regimen on health related quality-of-life: a time trade off study. Health and Quality of Life Outcomes, 14.
Jendle, J. H. , Rawshani, A. , Svensson, A. , Avdic, T. & Gudbjörnsdóttir, S. (2016). Indications for Insulin Pump Therapy in Type 1 Diabetes and Associations With Glycemic Control. Journal of Diabetes Science and Technology, 10 (5), 1027-1033.
Jendle, J. , Rinnert, K. , Westman, A. & Heinemann, L. (2016). Pilots and Diabetes Technology: Functional Health. Journal of Diabetes Science and Technology, 11 (2), 191-194.
Adolfsson, P. , Mattsson, S. & Jendle, J. (2015). Evaluation of glucose control when a new strategy of increased carbohydrate supply is implemented during prolonged physical exercise in type 1 diabetes. European Journal of Applied Physiology, 115 (12), 2599-2607.
Roze, S. , Saunders, R. , Brandt, A. -. , de Portu, S. , Papo, N. L. & Jendle, J. (2015). Health-economic analysis of real-time continuous glucose monitoring in people with Type 1 diabetes. Diabetic Medicine, 32 (5), 618-626.
Steineck, I. , Cederholm, J. , Eliasson, B. , Rawshani, A. , Eeg-Olofsson, K. , Svensson, A. , Zethelius, B. , Avdic, T. & et al. (2015). Insulin pump therapy, multiple daily injections, and cardiovascular mortality in 18 168 people with type 1 diabetes: observational study. BMJ-BRITISH MEDICAL JOURNAL, 350.
Jendle, J. , Ridderstrale, M. , Jensen, H. H. , Bøgelund, M. , Jensen, M. M. , Ericsson, A. & Evans, M. (2015). Investigating the short-term impact of poor glycemic control on the daily lives of people with type 2 diabetes. Value in Health, 18 (3), A65-A65.
Evans, M. , Ridderstråle, M. , Jensen, H. H. , Bøgelund, M. , Jensen, M. M. , Ericsson, Å. & Jendle, J. (2015). Quantifying The Short-Term Impact of Changes In Hba1c, Weight And Insulin Regimen on Health Related Quality-of-Life. Value in Health, 18 (7), A616-A616.
Jendle, J. , Blonde, L. , Rosenstock, J. , Woo, V. , Gross, J. , Jiang, H. & Milicevic, Z. (2014). Better glycaemic control and less weight gain with once weekly dulaglutide vs bedtime insulin glargine, both combined with thrice daily lispro, in type 2 diabetes (AWARD-4). Diabetologia, 57 (Suppl 1), S23-S24.
Yousef, M. , Westman, A. , Lindberg, A. , de Lacerda, C. & Jendle, J. (2014). Glucose Changes and Working Memory in Individuals with Type 1 Diabetes During Air Pressure Changes Simulating Skydiving. Diabetes Technology & Therapeutics, 16 (1), 56-62.
Khalili, P. , Sundström, J. , Jendle, J. , Lundin, F. , Jungner, I. & Nilsson, P. M. (2014). Sialic acid and incidence of hospitalization for diabetes and its complications during 40-years of follow-up in a large cohort: The Värmland survey. Primary Care Diabetes, 8 (4), 352-357.
Khalili, P. , Sundström, J. , Franklin, S. S. , Jendle, J. , Lundin, F. , Jungner, I. & Nilsson, P. M. (2012). Combined effects of brachial pulse pressure and sialic acid for risk of cardiovascular events during 40 years of follow-up in 37 843 individuals. Journal of Hypertension, 30 (9), 1718-1724.
Adolfsson, P. , Örnhagen, H. , Eriksson, B. M. , Cooper, K. & Jendle, J. (2012). Continuous glucose monitoring: a study of the Enlite sensor during hypo- and hyperbaric conditions. Diabetes Technology & Therapeutics, 14 (6), 527-532.
Valentine, W. J. , Jendle, J. , Saraheimo, M. , Thorsteinsson, B. , Pollock, R. F. & Lammert, M. (2012). Evaluating the cost-effectiveness of reduced mild hypoglycaemia in subjects with Type 1 diabetes treated with insulin detemir or NPH insulin in Denmark, Sweden, Finland and the Netherlands. Diabetic Medicine, 29 (3), 303-312.
Home, P. D. , Meneghini, L. , Wendisch, U. , Ratner, R. E. , Johansen, T. , Christensen, T. E. , Jendle, J. , Roberts, A. P. & et al. (2012). Improved health status with insulin degludec compared with insulin glargine in people with Type 1 diabetes. Diabetic Medicine, 29 (6), 716-720.
Jendle, J. , Martin, S. A. & Milicevic, Z. (2012). Insulin and GLP-1 analog combinations in type 2 diabetes mellitus: a critical review. Expert Opinion on Investigational Drugs, 21 (10), 1463-1474.
Adolfsson, P. , Ornhagen, H. , Eriksson, B. M. , Gautham, R. & Jendle, J. (2012). In-vitro performance of the Enlite sensor in various glucose concentrations during hypobaric and hyperbaric conditions. Journal of Diabetes Science and Technology, 6 (6), 1375-1382.
Jendle, J. , Christensen, J. H. , Kvistgaard, H. , Gregersen, N. & Rittig, S. (2012). Late-onset familial neurohypophyseal diabetes insipidus due to a novel mutation in the AVP gene. Clinical Endocrinology, 77 (4), 586-592.
Jendle, J. , Alvarsson, M. , Hanås, R. & Attvall, S. (2012). Mätning av blodketoner[Measuring blood ketones]: när, var och hur[when, where and how]. Läkartidningen, 109 (45), 2031-2032.
Jendle, J. , Adolfsson, P. & Ornhagen, H. (2012). Swedish recommendations on recreational diving and diabetes mellitus. Diving and Hyperbaric Medicine, 42 (4), 231-233.
Jendle, J. , Torffvit, O. , Ridderstråle, M. , Ericsson, Å. , Nilsen, B. & Bøgelund, M. (2012). Willingness to pay for diabetes drug therapy in type 2 diabetes patients: based on LEAD clinical programme results. Journal of Medical Economics, 15 (Suppl 2), 1-5.
Jendle, J. , Ridderstråle, M. , Torfvitt, O. , Ericsson, Å. & Larsen, S. (2012). Willingness-to-pay for benefits associated with basal insulin treatment of type 2 diabetes. Journal of Medical Economics, 15 (2), 261-263.
Jendle, J. , Adolfsson, P. , Attvall, S. & Örnhagen, H. (2011). Dykning vid diabetes möjligt men inte riskfritt [Diving in diabetes possible but not without risks]. Läkartidningen, 108 (44), 2230-2231.
Jendle, J. & Adolfsson, P. (2011). Impact of high altitudes on glucose control. Journal of Diabetes Science and Technology, 5 (6), 1621-1622.
Birkeland, K. I. , Home, P. D. , Wendisch, U. , Ratner, R. E. , Johansen, T. , Endahl, L. A. , Lyby, K. , Jendle, J. & et al. (2011). Insulin degludec in type 1 diabetes: a randomized controlled trial of a new-generation ultra-long-acting insulin compared with insulin glargine. Diabetes Care, 34 (3), 661-665.
Faerch, M. , Corydon, T. J. , Rittig, S. , Christensen, J. H. , Hertz, J. M. & Jendle, J. (2010). Skewed X-chromosome inactivation causing diagnostic misinterpretation in congenital nephrogenic diabetes insipidus. Scandinavian Journal of Urology and Nephrology, 44 (5), 324-330.
Khalili, P. , Flyvbjerg, A. , Frystyk, J. , Lundin, F. , Jendle, J. , Engström, G. & Nilsson, P. M. (2010). Total adiponectin does not predict cardiovascular events in middle-aged men in a prospective, long-term follow-up study. Diabetes & Metabolism, 36 (2), 137-143.
Jendle, J. , Torffvit, O. , Ridderstråle, M. , Lammert, M. , Ericsson, Å. & Bøgelund, M. (2010). Willingness to pay for health improvements associated with anti-diabetes treatments for people with type 2 diabetes. Current Medical Research and Opinion, 26 (4), 917-923.
Adolfsson, P. , Örnhagen, H. & Jendle, J. (2009). Accuracy and reliability of continuous glucose monitoring in individuals with type 1 diabetes during recreational diving. Diabetes Technology & Therapeutics, 11 (8), 493-497.
Jendle, J. , Nauck, M. A. , Matthews, D. R. , Frid, A. , Hermansen, K. , During, M. , Zdravkovic, M. , Strauss, B. J. & et al. (2009). Weight loss with liraglutide, a once-daily human glucagon-like peptide-1 analogue for type 2 diabetes treatment as monotherapy or added to metformin, is primarily as a result of a reduction in fat tissue. Diabetes, obesity and metabolism, 11 (12), 1163-1172.
Goodall, G. , Jendle, J. , Valentine, W. J. , Munro, V. , Brandt, A. B. , Ray, J. A. , Roze, S. , Foos, V. & et al. (2008). Biphasic insulin aspart 70/30 vs. insulin glargine in insulin naïve type 2 diabetes patients: modelling the long-term health economic implications in a Swedish setting. International journal of clinical practice (Esher), 62 (6), 869-876.
Adolfsson, P. , Örnhagen, H. & Jendle, J. (2008). The benefits of continuous glucose monitoring and a glucose monitoring schedule in individuals with type 1 diabetes during recreational diving. Journal of Diabetes Science and Technology, 2 (5), 778-784.
Jendle, J. & Norberg, B. (2007). Kliniska erfarenheter av behandling med Levemir [Clinical experiences with Levemir treatment].. Läkartidningen, 104 (1-2), 54-54.
Kølendorf, K. , Ross, G. P. , Pavlic-Renar, I. , Perriello, G. , Philotheou, A. , Jendle, J. , Gall, M. & Heller, S. R. (2006). Insulin detemir lowers the risk of hypoglycaemia and provides more consistent plasma glucose levels compared with NPH insulin in Type 1 diabetes. Diabetic Medicine, 23 (7), 729-735.
Himmelmann, A. , Jendle, J. , Mellén, A. , Petersen, A. H. , Dahl, U. L. & Wollmer, P. (2003). The impact of smoking on inhaled insulin. Diabetes Care, 26 (3), 677-682.
Brunner, G. A. , Balent, B. , Ellmerer, M. , Schaupp, L. , Siebenhofer, A. , Jendle, J. , Okikawa, J. & Pieber, T. R. (2001). Dose-response relation of liquid aerosol inhaled insulin in type I diabetic patients.. Diabetologia, 44 (3), 305-308.
Lundström, A. , Jendle, J. , Stenström, B. , Toss, G. & Ravald, N. (2001). Periodontal conditions in 70-year-old women with osteoporosis. Swedish Dental Journal, 25 (3), 89-96.
Jendle, J. , Karlberg, B. E. & Arborelius, M. (1996). An exploration of intrapulmonary insulin administration in anaesthetized and mechanically ventilated pigs. Scandinavian Journal of Clinical and Laboratory Investigation, 56 (3), 251-258.
Jendle, J. & Karlberg, B. E. (1996). Effects of intrapulmonary insulin in patients with non-insulin-dependent diabetes. Scandinavian Journal of Clinical and Laboratory Investigation, 56 (6), 555-561.
Jendle, J. & Karlberg, B. E. (1996). Intrapulmonary administration of insulin to healthy volunteers. Journal of Internal Medicine, 240 (2), 93-98.
Jendle, J. , Karlberg, B. E. , Persliden, J. , Franzén, L. & Arborelius, M. (1995). Delivery and Retention of an Insulin Aerosol Produced by a New Jet Nebulizer. Journal of Aerosol Medicine, 8 (3), 243-254.
Nilsson, L. , Nilsson, M. & Jendle, J. (1988). Subpopulations of variants resistant to imipenem in Pseudomonas aeruginosa. Journal of Antimicrobial Chemotherapy, 22 (5), 643-649.

Articles, reviews/surveys

Jendle, J. , Grunberger, G. , Blevins, T. , Giorgino, F. , Hietpas, R. T. & Botros, F. T. (2016). Efficacy and Safety of Dulaglutide in the Treatment of Type 2 Diabetes: A Comprehensive Review of the Dulaglutide Clinical Data Focusing on the AWARD Phase 3 Clinical Trial Program. Diabetes/Metabolism Research Reviews, 32 (8), 776-790.

Chapters in books

Jendle, J. (2016). Diabetes Melitus: Typ 1-diabetes, Typ 2-diabetes. In: Maria Hagströmer, Eva Jansson, FYSS 2017: Fysisk aktivitet i sjukdomsprevention och sjukdomsbehandling (pp. 371-390). Stockholm: Läkartidningen Förlag AB.

Conference papers