Medicine

Research groups

• Acute respiratory tract infections
• BBC - Bowel and Bladder disorders in Children
• Bioinformatics
• Cancer Epidemiology
• Cardiovascular Research Centre (CVRC) - translational cardiovascular research
• Cellular and Molecular Virology
• Circulating biomarkers för detection and surveillance of cancer
• Clinical and Experimental psychophysiology & Psychopharmacology
• Clinical Epidemiology and Biostatistics
• Cognitive medicine and biomarkers
• Development of novel chitosan-based scaffolds for cartilage repair
• Diabetes and Retinopathy
• Diabetes Endocrinology and Metabolism
• Digital Psychological Treatment
• EnForce
• Experimental neuropsychiatry and ageing
• Geriatrics
• Hepatitis B, D och C
• Immunoneuropsychiatry (INP)
• Immunoprofiling of Inflammation (iPi)
• Infection & inflammation (i&i)
• Inflammatory bowel disease and translational gastroenterology
• Inflammatory Response and Infection Susceptibility Centre (iRiSC)
• Metabolomics and exposome research
• Molecular cardiovascular research
• Neurodevelopmental disorders in children, adolescents and young adults
• Nutrition Gut Brain Axis
• Obesity and metabolic health
• Perioperative care and Pedagogical Processes (PEPP)
• Physiotherapy, prevention and pulmonary function
• Placenta research group
• Platelet function and coagulation in health and disease
• Psychiatric epidemiology
• Research based education in the health professions
• Stroke and other CNS injuries
• Swimming-induced pulmonary edema (SIPE)
• The ageing gut (TAG)
• Treatment in Upper and lower limb Malformation or Amputation (TUMA)
• Viral pathogenesis and vaccine development
• Wellbeing promotion using care environments and technologies (WellCET)

Research projects

Active projects

• 1952-1956 Birth Cohort
• 1970-2000 Birth Cohort
• 1-methyl Nicotinamide-driven ImmunoMOdulation in glioblastoma (NIMO)
• 3TR
• A sealed therapeutic shoe or cast as treatment of diabetic foot ulcers - a randomized controlled trial
• Achieving good glycemic control early after onset of diabetes is cost effective for patients with type 1 diabetes in Sweden
• Activity patterns in the abdominal and back musculature
• ADAPTide: decrypting sustainable and responsive nutrition by mapping the effects of plant-based foods on metabolic profiling
• Adherence to screening program for diabetes retinopathy
• Adrenergic signalling in cancer progression
• Adult dysplasia of the hip; the role of labral pathology and effect of pelvic tilt.
• Advances in workplace-based learning in health professions education (AWL-HPE)
• Age-associated gastrointestinal symptoms
• Ageing, influences on treatment modalities and health outcomes
• Age-related hearing impairment (ARHI) - a longitudinal epidemiological study.
• APRILD - Mönstertolkning med artificiella neurala nätverk vid interstitiella lungsjukdomar
• Assessment of anorectal function in patients with inflammatory bowel disease.
• Assessment of Capacity for Myoelectric Control (ACMC)
• Bacteriocins in prevention and treatment of infections
• Behandling av peniscancer som metastaserat till lymfkörtlar eller andra organ
• Biological aspects of ageing
• Biosignatures and functional network structures
• Bowel And Bladder function in Infant Toilet Training (BABITT) - a randomized multicenter intervention study
• Bowel And Bladder function In Swedish 4-year old children - a cross sectional study (BABIS-4)
• Butyrate-promoting dietary fibres as a potential strategy for the prevention of type-2 diabetes
• Causes and consequences of lifespan multi-morbidity in ADHD
• CloROP - Clonidine as pain relief during eye examinations in preterm infants
• Comorbid Conditions of Attention deficit / hyperactive disorders (CoCA)
• Comorbidity, mortality and disease progression/severity in multiple sclerosis
• Comparing the efficacy of encapsulated and non-encapsulated probiotics to affect brain function
• Compositional analysis of the human gut microbiota along the entire large intestine
• Computer navigated hip arthroplasty
• Congenital limb deficiency - early intervention and later outcomes
• Connection between primary and secondary hemostasis
• Cost of complications in people with type 2 diabetes: Evidence from 20 years of Swedish national health registry data
• Creating Learning Environments for Compassionate Care
• Cross-talk between platelets and the vessel wall
• Datortomografisk lungembolidiagnostik med minimal mängd kontrastmedel
• Development of expression platforms for antigens for vaccine candidates and diagnostic tools
• Development of the Assisting Hand Assessment-PAD: A Rasch-built performance measure for people with unilateral upper limb prosthesis (P), amputation (A) or reduction deficiency (D)
• Different amounts of carbohydrates during prolonged physical activity and performance in type 1 diabetes
• Digital monocyte
• Dignity conserving care for older persons with palliative care needs
• Effect of serotonergic stimulation on the gut-brain axis in irritable bowel syndrome patients compared with healthy subjects applying functional brain imaging
• Effects of Bilberry and/or Oat intake on lipids, inflammation and exercise capacity after Acute Myocardial Infarction (BIOAMI): a randomized, double-blind, placebo-controlled trial
• Effects of multi-modal non-pharmacological treatment in adult patients with ADHD - A randomised controlled study
• Effects of Nutrition and Lifestyle on Impulsive, Compulsive, and Externalizing behaviours (Eat2beNICE)
• Elderly, their relatives and healthcare professionals' experiences of health services for elderly. A qualitative study
• Emfysemkvantifiering i CT-bilder med artificiellt neuralt nätverk
• Epidemiology and Genetic epidemiology
• Establishing a novel gut-brain axis model
• Fundoscopy in elderly people with diabetes in Sweden
• Genetic variations in genes associated with inflammation and predisposition for altered biomarker profiles
• Genome, genome regulation and expression
• Grade III-V Isthmic Spondylolisthesis in Children and Teenagers. A Long-Term Follow-Up of In Situ Fusion
• Health economic evaluations of cervical cancer screening
• Human exposure to per- and polyfluoroalkyl substances? Role of the gut microbiome and bile acid metabolism in mediating impact (PFASgut)
• Human papillomavirus, biological and prognostic markers in primary vaginal and vulvar cancer
• Human papillomavirus, gene variation and protein expression as prognostic markers for metastasizing penile cancer
• Hur påverkar fibrer mag- och tarmbarriären hos äldre personer
• Hypoglycaemia reduction in subpopulations with type 1 or type 2 diabetes after switching to insulin degludec from other basal insulins: a multi-national, multi-centre, prospective, observational study (ReFLeCT).
• Identification of dietary fibres that promotes butyrate production
• Ikaria Healthy Ageing
• ImprUV+ - An analytical framework to explore the effects of UV during plant growth on human health
• Infusion of Mescenchymal cells in newly diagnosed type 1 diabetic subjects
• Interaction between dietary protein and fibre fermentation - its functional consequences
• Interleukin-6 classic and trans-signaling in human monocytes - molecular mechanisms and functional consequences
• Investigation of endocrine-disrupting chemicals as contributors to progression of metabolic dysfunction-associated steatotic liver disease
• Irritable bowel syndrome in primary health care
• Ketamine as an Alternative Treatment to ECT in Major Depressive Disorder
• Late onset of inflammatory bowel disease
• Late onset of inflammatory bowel disease
• Learning of practical skills
• LITMUS
• Long-term consequences of Attention-deficit/hyperactivity disorder (ADHD) in adults
• Lower extremity amputations in Sweden
• Lymfkörtelkirurgi och komplikationer
• Mapping signal transduction in inflammation (Umbrella project)
• Maternal and child health in a HIV/AIDS high endemic area (Mozambique)
• Metabolome in traumatic brain injury - from biomarkers and pathways to clinical translation (pathTBI)
• Microbes inside
• Mode of action of butyrate in the human colon
• Molecular triage for HPV-positive samples in cervical cancer screening
• Municipality chief nurses (MAS) obstacles and possibilities to fulfill their duties in municipal health care.
• NanoSafety2
• NANOSIGN
• Network medicine and systems biological approaches to modeling inflammation
• Newbreed
• NORDTREAT
• Nutritional status in older people in need of health and social care
• Nyttan av cochleaimplantat (CI) hos vuxna - hörsel, livskvalitet och cognition
• PAN Protein - plant-based proteins contributing to a healthy and sustainable diet
• PenBus: inflammation, HPV och genetik vid peniscancer
• Peniscancer och risk för andra HPV associerade tumörformer
• Peniscancer och utredning med PET-CT
• Phenotyping and treatment of primary health care IBS patients
• Physiotherapeutic aspects on balance and walking deficits in multiple sclerosis
• Plastic antibodies and nanoplasmonic sensors in targeting risk markers of periodontitis and systemic disorders
• Platelet function in cardiothoracic surgery and cardiology
• Platelet function in transfusion medicine
• POPgut - The impact of persistent organic pollutants exposure on gut health
• Population-based studies of Attention-Deficit/Hyperactivity Disorder and Adverse Health Behaviors
• Post stroke fatigue
• Predicting Psychiatric and Medical Outcomes of Adult Attention Deficit Hyperactivity Disorder (ADHD).
• PREFECT
• Productivity losses associated with complications of diabetes: Evidence from 20 years of Swedish national health registry data on >200,000 people with type 1 and type 2 diabetes
• Prostate Cancer Stress Surveillance and Survival (ProSeSS): evaluation of a fast-track clinical workup for men with suspected prostate cancer
• Proteome signatures in IBD
• Psychological and physiological factors predicting tolerability and weight loss of intragastric balloon in combination with low energy diet and group treatment in adults with obesity
• Recreational diving in persons with type 1 and type 2 diabetes ? Advancing capabilities and recommendations
• Reference functions for blood borne and sexually transmitted infections (STI) in Sweden
• Referral to another level of health care - A prehospital patient safety study
• Regulation and early signs of immunosuppression in sepsis
• Risk of impaired vision due to diabetes retinopathy in the elderly with type 2 diabetes.
• Risks and benefits of ADHD medication
• Role of CARD8 for inflammation in vascular cells
• Role of NLRP3 inflammasome and interleukin-1 (IL-1) in cardiovascular disease
• Role of zinc finger proteins in cardiovascular diseases and cancer
• SAND 4 - Can we make single energy CT perform as good as dual energy CT in differentiating urinary acid stones from other urinary stones?
• SAND-projektet
• SANNI - Safe analgesia for neonatal intensive care
• Self-efficacy and health literacy impact on outcome after bariatric surgery
• Self-measurement of uric acid for patients with gout ? a feasibility study in primary care.
• Sensory reactivity in autism spectrum conditions
• Sentinel Node och peniscancer
• Silicone sock as treatment of heel fissures among people with diabetes - a randomized controlled trial
• Skin and wound care at end-of-life: A systematic review
• Stress-related morbidity and mortality in newly diagnosed cancer patients
• Systematic modelling: quantitative and semi-qualitative implementations of nutrition-microbe-gut-blood-brain interactions regarding the role of butyrate
• Systems Biology and Bioinformatics Analysis of Inhaled LPS Mouse Model Data from AstraZeneca
• The CDC4G study
• The development of an automatic cognitive screening test using Advanced Eye-Tracking Technology
• The effect of low energy diet in combination with cognitive behavioral therapy and intragastric balloons on weight loss and weight maintenance: a randomized controlled trial
• The effects of fermentable dietary fibre supplementation on intestinal permeability and inflammation in microscopic colitis
• To determine the butyrate transport capacity in vitro and in tissue samples from healthy individuals and from patients with digestive disorders
• Total knee arthroplasty in obese patients with and without prior bariatric surgery
• Towards technology-supported workplace based learning: needs analysis and design
• Two-point force systems in orthotics: theory and applications
• Understanding long-term opioid treatment to patients with chronic non-cancer pain in order to develop a method that promotes proper treatment.
• Unpuzzle - Unravelling molecular motifs from dietary fibers responsible for interaction with recognition receptors in human cells
• Urinary Stone Image Analysis Data Bank - SAND-projektet
• Validation of the self-report version of IPPA (Individually Prioritized Problem Assessment)
• X-HiDE
• Örebro Birth Cohort

Completed projects

• A systematic review of evaluation forms to assess interprofessional learning in undergraduate health professions education
• Ageing and the gastrointestinal microbiome: effects on immunology and cognitive function
• Allergic diseases in adolescence and depression in adulthood
• Assessment of difficulties in everyday life - validation of the Swedish self-administered version of World Health Organization Disability Assessment Schedule 2.0 in a psychiatric population
• Bibliometric analysis of research within the area of assistive technology devices
• Biomarkers and elderly health
• Can prosthetic wrist reduce compensatory movements among upper limb prosthesis users?
• Characteristics during adolescence and the risk of early-onset dementia
• Characteristics in childhood and adolescence relevant to chronic disease risk later in life
• Comparison of drop-in and scheduled appointments for people in need of foot orthoses.
• COSM
• Deep learning algorithms in predicting severe complications after bariatric surgery
• Development of a comprehensive elderly cohort
• Development of an in vivo butyrate sensor
• DID-ACT, European collaborative project on Clinical reasoning in health professions education.
• Dietary Fibers supporting Gut and Immune Function - from polysaccharide compound to health claim (FibeBiotics)
• Early life and intergenerational influences on immune-mediated disease risk
• Effect of a GnRH Injection on Ghrelin Concentrations in Girls With Suspected Premature Puberty
• Effect of the enzyme AN-PEP on gluten degradation in gluten-sensitive individuals
• Effects on subclinical heart failure in type 2 diabetic subjects on liraglutide treatment versus glimepiride both in combination with metformin
• Efficacy of dietary supplementation with Lactobacilllus reuteri for digestive health in an elderly population (ELROY)
• Exponering och upptag av kobolt - effekter på luftvägar och hud samt påverkan på inflammatoriska markörer vid hårdmetallframställning
• Factors of importance for morbidity and mortality in incident type 2 diabetes cases
• Faecal microbial transplantation (FMT) in IBS
• Faecal microbiota transfer in microscopic colitis
• Functional profiling of microbiota in the human gut
• Glucocorticoid-enhanced extinction-based exposure therapy in Irritable Bowel Syndrome
• Gluten reaction in children and young adults with cerebral palsy (CP)
• Gut-Brain axis in children and young adults with cerebral palsy (CP)
• Health Consequences of Environmental Exposures in Early Life
• Health-related quality of life worsening with increased severity of postprandial hyperglycaemic symptoms in individuals with type 1 or 2 diabetes
• HESPER Web- converting the HESPER instrument to a self-administrated version for web use
• Home-phototherapy for newborn infants with hyperbilirubinemia
• ICF- core sets for hearing loss; validation and operationalization of Brief ICF-Core set for hearing loss into a self-assessment instrument
• Identifying mechanisms for development of novel therapeutic strategies to treat age-associated constipation and diarrhoea (FODI)
• Integrative bioinformatics: combining clinical, physiological, brain imaging and molecular profiles
• Intervention with Cognitive Behavioral Therapy for subjects with IBS and its effects on visceral perception, abdominal complaints, psychological functioning and gut microbiota
• Labour market and health outcomes in adults with a family member who has a chronic illness: the role of family characteristics and social services
• Labour market outcomes and health after surviving cancer
• Life situation and ward consumption before suicide, among citizens in Örebro county
• Lifestyle, Biomarkers, and Atherosclerosis (LBA) Study
• Long term effect of Continuation Electroconvulsive therapy
• Microbe-host interactions in post-infectious irritable bowel syndrome (PI-IBS)
• Microbiota
• NanoSafety1
• Natural course, quality of life, heredity and mortality among children and adolescents who debuted with seizures 50 years ago, in Uppsala county
• Naturalförloppstudie
• Neurological complications pre-dating obesity and type 2 diabetes
• Nya diagnostiska markörer
• Outcomes of the SARS-CoV-2 pandemic in Örebro county
• Physical and psychological characteristics in adolescence and risk of cerebrovascular disease
• Physical and psychological characteristics in adolescence and subsequent gastrointestinal disease risk in adulthood
• Placental leptin, leptin receptor isoforms, and inflammation in obese women - in relation to birth weight of the outcome
• Prevalence and prognostic implications of cardiac injury in patients with influenza-like illness
• Prognostic predictors of ECT for depression
• PROMISE
• Prostate cancer
• Psycho(bio)logical effects of a probiotic mixture - an fMRI study
• Psychometric properties of two assessment tools for use in children with hemiplegic cerebral palsy - Childrens Hand-use Experience Questionnaire and the Pediatric Evaluation of Disability Inventory
• Risk och protective factors for adherence to wearing therapeutic shoes among people with diabetic foot complications
• Risk of frailty after cancer treatment
• Sports camps for adults with type 1 diabetes associated with improved self-estimated knowledge and glycemic control.
• The association between eHealth literacy and postoperative recovery in Swedish spekaing vs non-Swedish speaking persons undergoing surgery
• The effect of probiotic supplementation on antibody response against SARS-CoV-2 in healthy adults
• The micro-RNAome in cord blood of babies born small-for-gestational age
• The micro-RNAome in full-term placentas of babies born small-for-gestational age
• The natural history of multiple sclerosis
• The role of early psychological stress on cancer occurrence and outcomes
• The specific antibody response in children with cerebral palsy(CP).
• To evaluate anti-oxidative and anti-inflammatory effects of butyrate on the transport of large neutral amino acids such as tryptophan, a precursor of the neurotransmitter serotonin, in in vitro models
• Transglutaminases in children with cerebral palsy (CP)
• Translation and validation of the Swedish version of the World Health Organization - Disability Assessment Schedule (WHODAS) 2.0
• Traumatic limb amputation and depression risk
• Workplace Violence in the Ambulance Services Project; WASP