Geena ParamelTitle: Researcher School/office: School of Medical Sciences
Phone: +46 19 303801
About Geena Paramel
Geena Paramel received her PhD in Medical science with specialization in biomedicine at Örebro University, Sweden on a thesis titled ‘Innate Immunity in Human Atherosclerosis and Myocardial Infarction: Role of CARD8 and NLRP3’ in 2017. After conducting postdoctoral studies in metabolism lab at Dalhousie University, Canada, Geena returned to Örebro University and is actively involved both in research and teaching.
Geena Paramel is a member of a strong research environment Cardiovascular Research Center (CVRC) at Örebro University. One of the major focus of her research is to assess how endo- and exogenous factors regulate molecular and clinical changes in the proteins of innate immunity (such as CARD8, NLRP3, IL1β) that contribute to atherosclerosis. In addition to understanding the molecular mechanism, her research also aims to develop novel strategies and approaches (using drugs, small molecule inhibitors) to reduce inflammation, thrombosis, and vascular fibrosis, thus governing cardiovascular outcome. Her research interest extends to the genetic variation studies in relevance to inflammatory diseases.
Figure1: Expression of CARD8 protein (DAB/brown) in the endothelial cells (vWF/Red) of human carotid atherosclerotic plaque. https://doi.org/10.1038/s41598-020-73600-4
Geena Paramel is involved in teaching advanced level courses both at the School of Health and sciences and Medical sciences. She is the course coordinator for the Master level course, Research overview and design course (MC2034/BL2009/MC036A) and semester 7 in the medical program. Her teaching responsibilities in the International master program in the department of medical science includes literature review writing, lectures and holding Problem based learning (PBL) sessions.
Geena Paramel has ongoing collaboration with Dalhousie University, Canada, Karolinska Institute and Swedish biotech companies.