Biomedicine

Research groups

• Adaptive immunity in microscopic colitis and colon cancer
• Antimicrobial therapy
• Bioinformatics
• Bioinformatics in Translational Medicine(BIT-M)
• Cardiovascular Research Centre (CVRC) - translational cardiovascular research
• Cellular and Molecular Virology
• Circulating biomarkers för detection and surveillance of cancer
• Clinical genomics
• Development of novel chitosan-based scaffolds for cartilage repair
• Experimental neuropsychiatry and ageing
• HPV related cancer, precision medicine in prevention, screening and diagnostics
• Immunoprofiling of Inflammation (iPi)
• Infection & inflammation (i&i)
• Inflammation, Genetics and Drug Discovery in Cardiovascular Systems
• Inflammatory Response and Infection Susceptibility Centre (iRiSC)
• Innate immunity in cardiovascular disease
• Molecular cardiovascular research
• Molecular Systems Biology
• Platelet function and coagulation in health and disease
• Systemmedicin
• The ageing gut (TAG)
• Viral pathogenesis and vaccine development

Research projects

Active projects

• Bacteriocins in prevention and treatment of infections
• Bacteriocins in the prevention and treatment of bacterial infections
• Behandling av peniscancer som metastaserat till lymfkörtlar eller andra organ
• Cell Painting: a novel tool in toxicology (CPTox)
• Circulating biomarkers for the diagnostics and monitoring of cancer.
• Cobalt in the hard metal industry - lung and skin exposure and the implications for keratinocytes with regards to inflammasome activity
• Connection between primary and secondary hemostasis
• Cross-talk between platelets and the vessel wall
• Development and characterization of novel antimicrobial compounds
• Developvaccines@oru
• Diagnosis and treatment of periodontitis
• E. coli-induced inflammation
• Exposure to particles and biomarkers of inflammatory responses in workers in pulp and paper industry
• Functional studies of protein-protein interactions between flavivirus and the host cell
• Gene variants of the NLRP3 inflammasome in Neisseria meningitidis-induced severe infection
• Gene variants of the NLRP3 inflammasome in Staphylococcus aureus-induced severe infection
• Genetic variations in genes associated with inflammation and predisposition for altered biomarker profiles
• Ikaria Healthy Ageing
• Interleukin-6 as a therapeutic target for atherosclerosis
• Intracellular bacterial communities (IBC) and recurrent urinary tract infections
• Investigation of endocrine-disrupting chemicals as contributors to progression of metabolic dysfunction-associated steatotic liver disease
• Link between primary hemostasis and inflammation
• Lymfkörtelkirurgi och komplikationer
• MCbär-Swedens first study regarding meningococcal carriage
• Mechanisms and treatment of periodontal infection and associated systemic inflammation
• Molecular epidemiology of the Tick borne encephalitis virus
• NanoSafety2
• NANOSIGN
• Neisseria meningitidis-induced sepsis
• Network medicine and systems biological approaches to modeling inflammation
• Novel peptide therapeutics against infections caused by enveloped viruses
• PenBus: inflammation, HPV och genetik vid peniscancer
• Peniscancer och risk för andra HPV associerade tumörformer
• Plastic antibodies and nanoplasmonic sensors in targeting risk markers of periodontitis and systemic disorders
• Platelet function in cardiothoracic surgery and cardiology
• Platelet function in transfusion medicine
• Prognostic biomarkers for patients with prostate cancer
• Regulation and early signs of immunosuppression in sepsis
• Regulation of Inflammasomes
• Reprogrammed monocytes during infections and sepsis
• Retinoic acid in acute ischemia and heart failure: from genes to left ventricular performance
• Role of CARD8 for inflammation in vascular cells
• Role of NLRP3 inflammasome and interleukin-1 (IL-1) in cardiovascular disease
• Role of zinc finger proteins in cardiovascular diseases and cancer
• S. aureus-induced sepsis
• Sentinel Node och peniscancer
• The Blue Muffin Study - Impact of gut physiology and function on the formation of bioactive oligomers upon dietary fibre consumption
• The detrimental effect of bacterial infections in the cf lung

Completed projects

• Cellbiokemiska studier avseende aminosyratransport hos fibroblaster från barn med autism och betydande uppmärksamhetsproblem (ADHD)
• Development of edible flavivirus vaccines
• Development of edible vaccines against Tick-Borne encephalitis (TBE)
• Effect of aryl hydrocarbon receptor (AhR) ligands on human colonic intraepithelial lymphocytes
• Effects of perfluorinated compounds on the hepatic fatty acid oxidation in avian embryos using the tritium release assay
• Functional characterization of tyrosine, alanine and tryptophan transport in human fibroblast cells
• Induced Pluripotent Stem Cells (iPS) to identify alterations of neurogenesis associated with autism
• Inflammasome activity and regulation in neutrophils
• Inflammation and fibrosis- what are the mechanisms ?
• Lifestyle, Biomarkers, and Atherosclerosis (LBA) Study
• Multiresistant ESBL-producing uropathogens - studies of antibacterial strategies and pathogenesis mechanisms
• Muscarin acetylcholin receptorbindningsstudier i fibroblaster från Attention-Deficit/Hyperactivity Disorder (ADHD) patienter
• NanoSafety1
• Occupational particle exposure: Different environments, but the same risks?
• Patient-Derived Stem Cells (iPS) for Phosphoproteomic Profiling Neuropsychopathology
• Preclinical development of simple vaccines from dna launched suicidal flaviviruses
• Quartz- and particle exposure in iron foundries- mechanisms and impact on inflammation and coagulation markers for respiratory effects and cardiovascular disease
• Simple vaccines from DNA launched suicidal flaviviruses
• SP110 as a novel regulator of innate immune inflammasomes
• Surveillance of viral tick-borne zoonosis using novel strategies