Biomedicine

Research teams

• Demirel Group
• Experimental Neuropsychiatry
• Functional Bioinformatics
• Gut health
• HPV induced cancer
• Ikaria Healthy Ageing
• Immune response and antibacterial strategies in urinary tract infection
• Immunoprofiling of Inflammation (iPi)
• Immunosuppression and Myeloid cells in Inflammatory Diseases (iMiD)
• Inflammasome activation and regulation in innate immunity
• Inflammation and fibrosis ? what are the mechanisms?
• Inflammatorisk påverkan vid exponering för luftföroreningar i olika arbetsmiljöer
• Inter-individual variations - host tolerance vs. increased risk
• Meningococcal carriage or disease-what decides the outcome?
• Molecular cardiovascular research
• Molecular flavivirus research
• Novel antibacterial agents and bacterial sensors in the fight against infections
• Peile cancer
• Platelet and thrombosis research
• Prostate cancer
• Sepsis
• The immune defence of the gut mucosa
• Urinary bladder cancer
• Urologi - Njursten

Research projects

Active projects

• Aminosyratransport/omega-3 och-6 fettsyresammansättningen i fibroblaster från patienter med schizofreni och bipolär sjukdom
• Bacteriocins in prevention and treatment of infections
• Behandling av peniscancer som metastaserat till lymfkörtlar eller andra organ
• Cellbiokemiska studier avseende aminosyratransport hos fibroblaster från barn med autism och betydande uppmärksamhetsproblem (ADHD)
• Cobalt in the hard metal industry - lung and skin exposure and the implications for keratinocytes with regards to inflammasome activity
• Connection between primary and secondary hemostasis
• Cross-talk between platelets and the vessel wall
• Development of edible vaccines against Tick-Borne encephalitis (TBE)
• Developvaccines@oru
• Do loss of XXX, a mitochondrial transport protein, have a significant role in cancer metabolism?
• E. coli-induced inflammation
• Effects of perfluorinated compounds on the hepatic fatty acid oxidation in avian embryos using the tritium release assay
• Exposure to particles and biomarkers of inflammatory responses in workers in pulp and paper industry
• Functional studies of protein-protein interactions between flavivirus and the host cell
• Gene variants of the NLRP3 inflammasome in Neisseria meningitidis-induced severe infection
• Gene variants of the NLRP3 inflammasome in Staphylococcus aureus-induced severe infection
• Genetic variations in genes associated with inflammation and predisposition for altered biomarker profiles
• Induced Pluripotent Stem Cells (iPS) to identify alterations of neurogenesis associated with autism
• Inflammasome activity and regulation in neutrophils
• Inflammation and cardiovascular diseases
• Inflammation and fibrosis- what are the mechanisms ?
• Interaction between host and microbe during meningococcal disease
• Interleukin-6 as a therapeutic target for atherosclerosis
• Intracellular bacterial communities (IBC) and recurrent urinary tract infections
• Kartläggning av pro-inflammatoriska cytokiners roll: effekter på membrantransporten av tyrosin vid schizofreni och bipolär sjukdom
• Lifestyle, Biomarkers, and Atherosclerosis (LBA) Study
• Link between primary hemostasis and inflammation
• Lymfkörtelkirurgi och komplikationer
• MCbär-Swedens first study regarding meningococcal carriage
• Mechanisms and treatment of periodontal infection and associated systemic inflammation
• Molecular epidemiology of the Tick borne encephalitis virus
• Multiresistant ESBL-producing uropathogens - studies of antibacterial strategies and pathogenesis mechanisms
• Muscarin acetylcholin receptorbindningsstudier i fibroblaster från Attention-Deficit/Hyperactivity Disorder (ADHD) patienter
• NanoSafety Project
• Neisseria meningitidis-induced sepsis
• Network medicine and systems biological approaches to modeling inflammation
• Occupational particle exposure: Different environments, but the same risks?
• Patient-Derived Stem Cells (iPS) for Phosphoproteomic Profiling Neuropsychopathology
• PenBus: inflammation, HPV och genetik vid peniscancer
• Peniscancer och risk för andra HPV associerade tumörformer
• Plastic antibodies and nanoplasmonic sensors in targeting risk markers of periodontitis and systemic disorders
• Platelet function in cardiothoracic surgery and cardiology
• Platelet function in transfusion medicine
• Platelet proteome and function in hematological diseases
• Preclinical development of simple vaccines from dna launched suicidal flaviviruses
• Quartz- and particle exposure in iron foundries- mechanisms and impact on inflammation and coagulation markers for respiratory effects and cardiovascular disease
• Regulation and early signs of immunosuppression in sepsis
• Regulation of Inflammasomes
• Reprogrammed monocytes during infections and sepsis
• Retinoic acid in acute ischemia and heart failure: from genes to left ventricular performance
• Role of CARD8 for inflammation in vascular cells
• Role of NLRP3 inflammasome and interleukin-1 (IL-1) in cardiovascular disease
• Role of zinc finger proteins in cardiovascular diseases and cancer
• S. aureus-induced sepsis
• Sentinel Node och peniscancer
• SP110 as a novel regulator of innate immune inflammasomes
• Surveillance of viral tick-borne zoonosis using novel strategies
• The detrimental effect of bacterial infections in the cf lung
• The role of the innate and adaptive immune response in inflammation associated colon cancer. Experimental studies in G-alpha-i2-deficient mice

Completed projects

• Development of edible flavivirus vaccines
• Effect of aryl hydrocarbon receptor (AhR) ligands on human colonic intraepithelial lymphocytes
• Functional characterization of tyrosine, alanine and tryptophan transport in human fibroblast cells
• Simple vaccines from DNA launched suicidal flaviviruses