John-Peter Ganda-MallTitle: Senior Lecturer School/office: School of Medical Sciences
Phone: +46 19 303349
About John-Peter Ganda-Mall
John-Peter Ganda Mall has a background in biomedicine and received his candidate - and Master from Örebro University. In both of his thesis's he worked on the gut flora and immunology in inflammatory bowel disease. His interest in immunology has since lived on to his PhD study which is about how the immune system in the gut changes with age and whether non-digestible polysaccharides (prebiotics) can strengthen the so-called intestinal barrier. The intestinal barrier is a key component of the immune system as it prevents the intrusion of microorganisms but at the same time mediates absorption of nutrients.
In order to study this, John-Peter has been involved in setting up two different techniques. The first being the Ussing chamber-method which makes it possible to measure the passage across the intestinal epithelium and simultaneously modulate the tissue in real time with different substances.The second method is based on drinking a sugar-solution which contains sugars that are absorbed at different locations in the intestine. At time of analysis, these sugars gives a measurement of the peremability at different locactions in the intestine.
With these powerful techniques, he hopes to find a prebiotic that can strengthen the immune system in the aging gut.