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John-Peter Ganda-Mall

Title: Researcher School/office: School of Medical Sciences

Email:

Phone: +46 19 303349

Room: C3119

John-Peter Ganda-Mall

About John-Peter Ganda-Mall

John-Peter Ganda Mall has a background in biomedicine and during his PhD at Örebro university studied how the immune system in the gut changes with age and whether non-digestible polysaccharides (prebiotics) can strengthen the so-called intestinal barrier. The intestinal barrier is a key component of the immune system as it prevents the intrusion of microorganisms but at the same time mediates absorption of nutrients.

In order to study this, John-Peter has been involved in setting up two different techniques. The first being the Ussing chamber-method which makes it possible to measure the passage across the intestinal epithelium and simultaneously modulate the tissue in real time with different substances.The second method is based on drinking a sugar-solution which contains sugars that are absorbed at different locations in the intestine. At time of analysis, these sugars gives a measurement of the peremability at different locactions in the intestine.

 

After completing his pHd, he received the international postdoc grant from the Swedish Research Council and worked at Vall d'Hebron Research Institute (Barcelona, ​​Spain) for over 2 years on the mucosal immune system in IBS. There he used electron microscopy, among other things, to study the activity of antibody-producing plasma cells and their interaction with the intestinal barrier and the enteric nervous system.

He is now back at NGBI at Örebro University and does research in 1) breakdown of fibres/proteins 2)  Studying the connection between the gut and the brain in neurodegenerative diseases such as Parkinson's disease in collaboration with the group in Barcelona.

 

Publications

Articles in journals |  Chapters in books |  Doctoral theses, comprehensive summaries |  Manuscripts | 

Articles in journals

Chapters in books

Doctoral theses, comprehensive summaries

Manuscripts