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Jonas Halfvarson

Title: Professor School/office: School of Medical Sciences

Email: jonas.halfvarson@oru.se

Phone: +46 19 303000, +46 738 082361

Room: X2212

Research subject

Medicine

Research environments

Nutrition-Gut-Brain Interactions Research Centre (NGBI)

About Jonas Halfvarson

In Sweden more than 61 000 individuals are affected by inflammatory bowel disease (IBD), including the predominant forms Crohn’s disease and ulcerative colitis. In the absence of a prevention strategies and curative treatment, the disease has a major impact on many affected individuals, including life-long medication, hospitalizations, recurring sick-leaves, and often a need for surgical intervention. IBD has a high and escalating incidence throughout the world, especially among teenagers and elderly, reflecting the strategic importance for the society at large, both from patient and health care perspectives.

My research goal is to improve the healthcare for individuals affected by IBD and thereby increasing their quality of life. I aim to accomplish this by identifying biomarkers that can be used to diagnose the diseases (diagnostic biomarkers) and to foresee who will progress to a severe disease status (prognostic biomarkers). Individuals who will progress to a severe disease status are in need of treatment with biologics already at diagnosis. Therefore, I aim to identify biomarkers that can be used to foresee who will respond from a specific treatment (predictive biomarkers) and who will benefit from taking the drug over a longer period of time (prognostic biomarkers).

Active projects

Completed projects

Microbiota

Research teams

Inflammatory bowel disease (IBD) and translational gastroenterology

Publications

Articles in journals | Articles, reviews/surveys | Chapters in books | Conference papers | Manuscripts |

Articles in journals

Wang, K. , Olén, O. , Emilsson, L. , Khalili, H. , Halfvarson, J. , Song, M. & Ludvigsson, J. F. (2023). Association of inflammatory bowel disease in first-degree relatives with risk of colorectal cancer: A nationwide case-control study in Sweden. International Journal of Cancer.
Peyrin-Biroulet, L. , Rahier, J. , Kirchgesner, J. , Abitbol, V. , Sebastian, S. , Armuzzi, A. , Karmiris, K. , Gisbert, J. P. & et al. (2023). I-CARE, a European prospective cohort study assessing safety and effectiveness of biologics in inflammatory bowel disease. Clinical Gastroenterology and Hepatology, 21 (3), 771-788.e10.
Leibovitzh, H. , Lee, S. H. , Raygoza Garay, J. A. , Espin-Garcia, O. , Xue, M. , Neustaeter, A. , Goethel, A. , Huynh, H. Q. & et al. (2023). Immune response and barrier dysfunction-related proteomic signatures in preclinical phase of Crohn's disease highlight earliest events of pathogenesis. Gut.
Sun, J. , Fang, F. , Olén, O. , Song, M. , Halfvarson, J. , Roelstraete, B. , Khalili, H. & Ludvigsson, J. F. (2023). Long-term risk of inflammatory bowel disease after endoscopic biopsy with normal mucosa: A population-based, sibling-controlled cohort study in Sweden. PLoS Medicine, 20 (2).
Shubhakar, A. , Jansen, B. C. , Adams, A. T. , Reiding, K. R. , Ventham, N. T. , Kalla, R. , Bergemalm, D. , Urbanowicz, P. A. & et al. (2023). Serum N-Glycomic Biomarkers Predict Treatment Escalation in Inflammatory Bowel Disease. Journal of Crohn's & Colitis.
Holmgren, J. , Fröborg, A. , Visuri, I. , Halfvarson, J. , Hjortswang, H. , Karling, P. , Myrelid, P. , Olén, O. & et al. (2023). The Risk of Serious Infections Before and After Anti-TNF Therapy in Inflammatory Bowel Disease: A Retrospective Cohort Study. Inflammatory Bowel Diseases, 19 (3), 339-348.
Forss, A. , Clements, M. , Myrelid, P. , Strid, H. , Söderman, C. , Wagner, A. , Andersson, D. , Hjelm, F. & et al. (2023). Ustekinumab Is Associated with Real-World Long-Term Effectiveness and Improved Health-Related Quality of Life in Crohn's Disease. Digestive Diseases and Sciences, 68 (1), 65-76.
Forss, A. , Clements, M. , Bergman, D. , Roelstraete, B. , Kaplan, G. G. , Myrelid, P. , Halfvarson, J. , Olén, O. & et al. (2022). A nationwide cohort study of the incidence of inflammatory bowel disease in Sweden from 1990 to 2014. Alimentary Pharmacology and Therapeutics, 55 (6), 691-699.
Halfvarson, J. , Ludvigsson, J. F. , Bresso, F. , Askling, J. , Sachs, M. C. & Olén, O. (2022). Age determines the risk of familial inflammatory bowel disease: A nationwide study. Alimentary Pharmacology and Therapeutics.
Kalla, R. , Adams, A. T. , Nowak, J. K. , Bergemalm, D. , Vatn, S. , Ventham, N. T. , Kennedy, N. A. , Ricanek, P. & et al. (2022). Analysis of systemic epigenetic alterations in inflammatory bowel disease: defining geographical, genetic, and immune-inflammatory influences on the circulating methylome. Journal of Crohn's & Colitis.
Shrestha, S. , Brand, J. S. , Järås, J. , Schoultz, I. , Montgomery, S. , Askling, J. , Ludvigsson, J. F. , Olen, O. & et al. (2022). Association between inflammatory bowel disease and spondyloarthritis: findings from a nationwide study in Sweden. Journal of Crohn's & Colitis, 16 (1), 1540-1550.
Mårild, K. , Söderling, J. , Lebwohl, B. , Green, P. H. , Pinto-Sanchez, M. I. , Halfvarson, J. , Roelstraete, B. , Olén, O. & et al. (2022). Association of Celiac Disease and Inflammatory Bowel Disease: A Nationwide Register-Based Cohort Study. American Journal of Gastroenterology, 117 (9), 1471-1481.
Chen, J. , Zhou, Y. , Sun, Y. , Yuan, S. , Kalla, R. , Sun, J. , Zhao, J. , Wang, L. & et al. (2022). Bidirectional Mendelian randomization analysis provides evidence for the causal involvement of dysregulation of CXCL9, CCL11 and CASP8 in the pathogenesis of ulcerative colitis. Journal of Crohn's & Colitis.
Sudhakar, P. , Salomon, B. , Verstockt, B. , Ungaro, R. , Aden, K. , D'Haens, G. , Komori, K. , Guay, H. & et al. (2022). Biomarkers for IBD using OLINK Proteomics inflammation panel: Preliminary results from the COLLIBRI consortium. Journal of Crohn's & Colitis, 16 (Suppl. 1), I123-I124.
Nowak, J. K. , Adams, A. T. , Kalla, R. , Lindstrøm, J. C. , Vatn, S. , Bergemalm, D. , Keita, Å. V. , Gomollón, F. & et al. (2022). Characterization of the circulating transcriptomic landscape in inflammatory bowel disease provides evidence for dysregulation of multiple transcription factors including NFE2, SPI1, CEBPB, and IRF2. Journal of Crohn's & Colitis, 16 (8), 1255-1268.
Everhov, Å. H. , Ludvigsson, J. F. , Järås, J. , Erichsen, R. , Pedersen, L. , Halfvarson, J. , Askling, J. , Ekbom, A. & et al. (2022). Colorectal Cancer in Childhood-onset Inflammatory Bowel Disease: A Scandinavian Register-based Cohort Study, 1969-2017. Journal of Pediatric Gastroenterology and Nutrition - JPGN, 75 (4), 480-484.
Everhov, Å. H. , Erichsen, R. , Järås, J. , Pedersen, L. , Halfvarson, J. , Askling, J. , Ekbom, A. , Ludvigsson, J. F. & et al. (2022). Colorectal cancer in elderly-onset inflammatory bowel disease: A 1969-2017 Scandinavian register-based cohort study. Alimentary Pharmacology and Therapeutics, 56 (7), 1168-1182.
Juzenas, S. , Hübenthal, M. , Lindqvist, C. M. , Kruse, R. , Steiert, T. A. , Degenhardt, F. , Schulte, D. , Nikolaus, S. & et al. (2022). Detailed transcriptional landscape of peripheral blood points to increased neutrophil activation in treatment-naïve inflammatory bowel disease. Journal of Crohn's & Colitis, 16 (7), 1097-1109.
Moraes Holst, L. , Halfvarson, J. , Carlson, M. , Hedin, C. , Kruse, R. , Lindqvist, C. M. , Bergemalm, D. , Almér, S. & et al. (2022). Downregulated Mucosal Autophagy, Alpha Kinase-1 and IL-17 Signaling Pathways in Active and Quiescent Ulcerative Colitis. Clinical and Experimental Gastroenterology, 15, 129-144.
Mårild, K. , Söderling, J. , Stephansson, O. , Axelrad, J. , Halfvarson, J. , Bröms, G. , Marsal, J. , Olén, O. & et al. (2022). Histological remission in inflammatory bowel disease and risk of adverse pregnancy outcomes: A nationwide study. EClinicalMedicine, 53.
Caron, B. , Abreu, M. T. , Siegel, C. A. , Panaccione, R. , Sands, B. E. , Dignass, A. , Turner, D. , Dotan, I. & et al. (2022). IOIBD Recommendations for Clinical Trials in Ulcerative Proctitis: the PROCTRIAL Consensus. Clinical Gastroenterology and Hepatology, 20 (11), 2169-2627.e1.
Zhulina, Y. , Udumyan, R. , Tysk, C. & Halfvarson, J. (2022). Mortality in patients with Crohn's disease in Örebro, Sweden 1963-2010. Scandinavian Journal of Gastroenterology, 57 (2), 153-164.
Nyström, N. , Prast-Nielsen, S. , Correia, M. , Globisch, D. , Engstrand, L. , Schuppe Koistinen, I. & Halfvarson, J. (2022). Mucosal and plasma metabolomes in new-onset paediatric inflammatory bowel disease: correlations with disease characteristics and plasma inflammation protein markers. Journal of Crohn's & Colitis.
Vatn, S. S. , Lindstrøm, J. C. , Moen, A. E. F. , Brackmann, S. , Tannæs, T. M. , Olbjørn, C. , Bergemalm, D. , Keita, Å. V. & et al. (2022). Mucosal Gene Transcript Signatures in Treatment Naïve Inflammatory Bowel Disease: A Comparative Analysis of Disease to Symptomatic and Healthy Controls in the European IBD-Character Cohort. Clinical and Experimental Gastroenterology, 15, 5-25.
Ludvigsson, J. F. , Sun, J. , Olén, O. , Song, M. , Halfvarson, J. , Roelstraete, B. , Khalili, H. & Fang, F. (2022). Normal Gastrointestinal Mucosa at Biopsy and Overall Mortality: Nationwide Population-Based Cohort Study. Clinical Epidemiology, 14, 889-900.
Sun, J. , Fang, F. , Olén, O. , Song, M. , Halfvarson, J. , Roelstraete, B. , Khalili, H. & Ludvigsson, J. F. (2022). Normal gastrointestinal mucosa at biopsy and subsequent cancer risk: nationwide population-based, sibling-controlled cohort study. BMC Cancer, 22 (1).
Everhov, Å. H. , Kalman, T. D. , Söderling, J. , Nordenvall, C. , Halfvarson, J. , Ekbom, A. , Ludvigsson, J. F. , Olén, O. & et al. (2022). Probability of Stoma in Incident Patients With Crohn's Disease in Sweden 2003-2019: A Population-based Study. Inflammatory Bowel Diseases, 28 (8), 1160-1168.
Salomon, B. , Bergemalm, D. & Halfvarson, J. (2022). Prognostic Biosignatures at Ileocecal Resection: Hope or Reality?. Journal of Crohn's & Colitis, 16 (6), 873-875.
Horrigan, J. , Louis, E. , Spinelli, A. , Travis, S. , Moum, B. , Salwen-Deremer, J. , Halfvarson, J. , Panaccione, R. & et al. (2022). The Real World Global Use of Patient-Reported Outcomes (PROs) for the Care of Patients With IBD. American Journal of Gastroenterology, 117 (10 Suppl.), S704-S705.
Thunberg, J. , Björkqvist, O. , Hedin, C. R. H. , Forss, A. , Söderman, C. , Bergemalm, D. , Olén, O. , Hjortswang, H. & et al. (2022). Ustekinumab treatment in ulcerative colitis: Real-world data from the Swedish inflammatory bowel disease quality register. United European Gastroenterology journal, 10 (7), 631-639.
Ludvigsson, J. F. , Holmgren, J. , Grip, O. , Halfvarson, J. , Askling, J. , Sachs, M. C. & Olén, O. (2021). Adult-onset inflammatory bowel disease and rate of serious infections compared to the general population: a nationwide register-based cohort study 2002-2017. Scandinavian Journal of Gastroenterology, 56 (10), 1152-1162.
Ludvigsson, J. F. , Olén, O. , Larsson, H. , Halfvarson, J. , Almqvist, C. , Lichtenstein, P. & Butwicka, A. (2021). Association between inflammatory bowel disease and psychiatric morbidity and suicide: A Swedish nationwide population-based cohort study with sibling comparisons. Journal of Crohn's & Colitis, 15 (11), 1824-1836.
Bröms, G. , Söderling, J. , Sachs, M. C. , Halfvarson, J. , Myrelid, P. , Ludvigsson, J. F. , Everhov, Å. H. & Olén, O. (2021). Capturing biologic treatment for IBD in the Swedish Prescribed Drug Register and the Swedish National Patient Register: a validation study. Scandinavian Journal of Gastroenterology, 56 (4), 410-421.
Eriksson, C. , Visuri, I. , Vigren, L. , Nilsson, L. , Kärnell, A. , Hjortswang, H. , Bergemalm, D. , Almer, S. & et al. (2021). Clinical effectiveness of golimumab in ulcerative colitis: a prospective multicentre study based on the Swedish IBD Quality Register, SWIBREG. Scandinavian Journal of Gastroenterology, 56 (11), 1304-1311.
Reinisch, W. , Gecse, K. , Halfvarson, J. , Irving, P. M. , Jahnsen, J. , Peyrin-Biroulet, L. , Rogler, G. , Schreiber, S. & et al. (2021). Clinical Practice of Adalimumab and Infliximab Biosimilar Treatment in Adult Patients With Crohn's Disease. Inflammatory Bowel Diseases, 27 (1), 106-122.
Mazzurana, L. , Bonfiglio, F. , Forkel, M. , D'Amato, M. , Halfvarson, J. & Mjösberg, J. (2021). Crohn's Disease Is Associated With Activation of Circulating Innate Lymphoid Cells. Inflammatory Bowel Diseases, 27 (7), 1128-1138.
Thunberg, J. , Björkqvist, O. , Olén, O. , Ludvigsson, J. F. , Eriksson, C. & Halfvarson, J. (2021). Drug survival and remission rates in ustekinumab treated ulcerative colitis: Results from the Swedish Inflammatory Bowel Disease register (SWIBREG). Journal of Crohn's & Colitis, 15 (Suppl. 1), S317-S317.
Rundquist, S. , Sachs, M. C. , Eriksson, C. , Olén, O. , Montgomery, S. & Halfvarson, J. (2021). Drug survival of anti-TNF agents compared with vedolizumab as a second-line biological treatment in inflammatory bowel disease: results from nationwide Swedish registers. Alimentary Pharmacology and Therapeutics (4), 471-483.
Rundquist, S. , Sachs, M. C. , Eriksson, C. , Olén, O. , Montgomery, S. & Halfvarson, J. (2021). Editorial: anti-TNF agents against vedolizumab as a second-line treatment? Not surprising tie game-authors' reply. Alimentary Pharmacology and Therapeutics, 53 (5), 642-643.
Kalla, R. , Adams, A. , Nowak, J. , Bergemalm, D. , Vatn, S. , Ventham, N. , Kennedy, N. , Ricanek, P. & et al. (2021). EPIGENETIC ALTERATIONS IN IBD: DEFINING GEOGRAPHICAL, GENETIC, AND IMMUNEIN-FLAMMATORY INFLUENCES ON THE CIRCULATING METHYLOME. Gut, 70 (Suppl. 4), A5-A5.
Björkqvist, O. , Rangel, I. , Serrander, L. , Magnusson, C. , Halfvarson, J. , Norén, T. & Bergman-Jungeström, M. (2021). Faecalibacterium prausnitzii increases following fecal microbiota transplantation in recurrent Clostridioides difficile infection. PLOS ONE, 16 (4).
Erichsen, R. , Olén, O. , Sachs, M. C. , Pedersen, L. , Halfvarson, J. , Askling, J. , Ekbom, A. , Ludvigsson, J. F. & et al. (2021). Hepatobiliary Cancer Risk in Patients with Inflammatory Bowel Disease: A Scandinavian Population-Based Cohort Study. Cancer Epidemiology, Biomarkers and Prevention, 30 (5), 886-894.
Ludvigsson, J. F. , Axelrad, J. , Halfvarson, J. , Khalili, H. , Larsson, E. , Lochhead, P. , Roelstraete, B. , Simon, T. G. & et al. (2021). Inflammatory bowel disease and risk of severe COVID-19: A nationwide population-based cohort study in Sweden. United European Gastroenterology journal, 9 (2), 177-192.
Axelrad, J. E. , Olén, O. , Sachs, M. C. , Erichsen, R. , Pedersen, L. , Halfvarson, J. , Askling, J. , Ekbom, A. & et al. (2021). Inflammatory bowel disease and risk of small bowel cancer: a binational population-based cohort study from Denmark and Sweden. Gut, 70 (2), 297-308.
Rundquist, S. , Sachs, M. C. , Eriksson, C. , Olén, O. , Montgomery, S. & Halfvarson, J. (2021). Letter: vedolizumab or a second anti-TNF-no difference in efficacy for primary biologic failures with IBD. Authors' reply. Alimentary Pharmacology and Therapeutics, 53 (9), 1046-1047.
Fart, F. , Salihovic, S. , McGlinchey, A. J. , Gareau, M. G. , Oresic, M. , Halfvarson, J. , Hyötyläinen, T. & Schoultz, I. (2021). Perfluoroalkyl substances are increased in patients with late-onset ulcerative colitis and induce intestinal barrier defects ex vivo in murine intestinal tissue. Scandinavian Journal of Gastroenterology, 56 (11), 1286-1295.
Visuri, I. , Eriksson, C. , Olén, O. , Cao, Y. , Mårdberg, E. , Grip, O. , Gustavsson, A. , Hjortswang, H. & et al. (2021). Predictors of drug survival: A cohort study comparing anti-tumour necrosis factor agents using the Swedish inflammatory bowel disease quality register. Alimentary Pharmacology and Therapeutics, 54 (7), 931-943.
Forss, A. , Clements, M. , Myrelid, P. , Strid, H. , Söderman, C. , Wagner, A. , Andersson, D. , Hjelm, F. & et al. (2021). Prospective observational study on Stelara (ustekinumab) assessing effectiveness in Crohn's disease (PROSE): a 16-week follow-up. Scandinavian Journal of Gastroenterology, 56 (6), 680-686.
Eriksson, C. , Rundquist, S. , Lykiardopoulos, V. , Udumyan, R. , Karlén, P. , Grip, O. , Söderman, C. , Almer, S. & et al. (2021). Real-world effectiveness of vedolizumab in inflammatory bowel disease: week 52 results from the Swedish prospective multicentre SVEAH study. Therapeutic Advances in Gastroenterology, 14.
Hirten, R. P. , Lakatos, P. L. , Halfvarson, J. & Colombel, J. F. (2021). Reply. Clinical Gastroenterology and Hepatology, 19 (6), 1301-1302.
Axelrad, J. E. , Olén, O. , Sachs, M. C. , Erichsen, R. , Pedersen, L. , Halfvarson, J. , Askling, J. , Ekbom, A. & et al. (2021). Reply: Survival in Crohn's disease-associated small bowel adenocarcinoma. Gut, 70 (5), 998-998.
Nordenvall, C. , Westberg, K. , Söderling, J. , Everhov, Å. H. , Halfvarson, J. , Ludvigsson, J. F. , Myrelid, P. & Olén, O. (2021). Restorative Surgery Is More Common In Ulcerative Colitis Patients with a High Income: A Population-Based Study. Diseases of the Colon & Rectum, 64 (3), 301-312.
Torres, J. , Halfvarson, J. , Rodríguez-Lago, I. , Hedin, C. R. H. , Jess, T. , Dubinsky, M. , Croitoru, K. , Colombel, J. & et al. (2021). Results of the Seventh Scientific Workshop of ECCO: Precision medicine in IBD- prediction and prevention of inflammatory bowel disease. Journal of Crohn's & Colitis, 15 (9), 1443-1454.
Kalla, R. , Adams, A. T. , Bergemalm, D. , Vatn, S. , Kennedy, N. A. , Ricanek, P. , Lindstrom, J. , Ocklind, A. & et al. (2021). Serum proteomic profiling at diagnosis predicts clinical course, and need for intensification of treatment in inflammatory bowel disease. Journal of Crohn's & Colitis, 15 (5), 699-708.
Bergemalm, D. , Andersson, E. , Hultdin, J. , Eriksson, C. , Rush, S. T. , Kalla, R. , Adams, A. T. , Keita, Å. V. & et al. (2021). Systemic Inflammation in Preclinical Ulcerative Colitis. Gastroenterology, 161 (5), 1526-1539.e9.
Franks, P. W. , Melén, E. , Friedman, M. , Sundström, J. , Kockum, I. , Klareskog, L. , Almqvist, C. , Bergen, S. E. & et al. (2021). Technological readiness and implementation of genomic-driven precision medicine for complex diseases. Journal of Internal Medicine, 290 (3), 602-620.
Everhov, Å. H. , Bruze, G. , Söderling, J. , Askling, J. , Halfvarson, J. , Westberg, K. , Malmborg, P. , Nordenvall, C. & et al. (2021). Women's earnings are more affected by inflammatory bowel disease than men's: a register-based Swedish cohort study. Journal of Crohn's & Colitis, 15 (6), 980-987.
Hirten, R. P. , Lakatos, P. L. , Halfvarson, J. & Colombel, J. F. (2020). A Users Guide to De-escalating Immunomodulator and Biologic Therapy in Inflammatory Bowel Disease. Clinical Gastroenterology and Hepatology, 18 (6), 1336-1345.
Halfvarson, J. , Ludvigsson, J. F. , Sachs, M. , Askling, J. & Olén, O. (2020). Age determines the risk of familial IBD: A nationwide case-control study. Journal of Crohn's & Colitis, 14 (Suppl. 1), S592-S593.
Nowak, J. K. , Lindström, J. C. , Kalla, R. , Ricanek, P. , Halfvarson, J. & Satsangi, J. (2020). Age, Inflammation, and Disease Location Are Critical Determinants of Intestinal Expression of SARS-CoV-2 Receptor ACE2 and TMPRSS2 in Inflammatory Bowel Disease. Gastroenterology, 159 (3), 1151-1154.
Ungaro, R. , Jordan, R. , Yzet, C. , Bossuyt, P. , Baert, F. , Vanasek, T. , D'Haens, G. R. , Joustra, V. W. & et al. (2020). CDEIS score of 2 is optimal cut-off associated with lower risk of disease progression in early Crohn's disease: Data from the CALM study. Journal of Crohn's & Colitis, 14 (Suppl. 1), S264-S266.
Olén, O. , Erichsen, R. , Sachs, M. C. , Pedersen, L. , Halfvarson, J. , Askling, J. , Ekbom, A. , Sørensen, H. T. & et al. (2020). Colorectal cancer in Crohn's disease: a Scandinavian population-based cohort study. The Lancet Gastroenterology & Hepatology, 5 (5), 475-484.
Olén, O. , Erichsen, R. , Sachs, M. C. , Pedersen, L. , Halfvarson, J. , Askling, J. , Ekbom, A. , Sørensen, H. T. & et al. (2020). Colorectal cancer in ulcerative colitis: a Scandinavian population-based cohort study. The Lancet, 395 (10218), 123-131.
Kim, H. , Alten, R. , Avedano, L. , Dignass, A. , Gomollón, F. , Greveson, K. , Halfvarson, J. , Irving, P. M. & et al. (2020). Correction to: The Future of Biosimilars: Maximizing Benefits Across Immune-Mediated Inflammatory Diseases (vol 80, pg 99, 2020). Drugs, 80 (10), 1039-1040.
Kalman, T. D. , Everhov, Å. H. , Nordenvall, C. , Sachs, M. C. , Halfvarson, J. , Ekbom, A. , Ludvigsson, J. F. , Myrelid, P. & et al. (2020). Decrease in primary but not in secondary abdominal surgery for Crohn's disease: nationwide cohort study, 1990-2014. British Journal of Surgery, 107 (11), 1529-1538.
Ungaro, R. C. , Yzet, C. , Bossuyt, P. , Baert, F. J. , Vanasek, T. , D'Haens, G. R. , Joustra, V. W. , Panaccione, R. & et al. (2020). Deep Remission at 1 Year Prevents Progression of Early Crohn's Disease. Gastroenterology, 159 (1), 139-147.
Juzenas, S. , Lindqvist, C. M. , Ito, G. , Dolshanskaya, Y. , Halfvarson, J. , Franke, A. & Hemmrich-Stanisak, G. (2020). Depletion of erythropoietic miR-486-5p and miR-451a improves detectability of rare microRNAs in peripheral blood-derived small RNA sequencing libraries. NAR Genomics and Bioinformatics, 2 (1).
Rundquist, S. , Sachs, M. , Eriksson, C. , Olén, O. , Montgomery, S. & Halfvarson, J. (2020). Effectiveness of anti-TNF vs. vedolizumab as a second biologic in IBD: results from national Swedish registers. Journal of Crohn's & Colitis, 14 (Suppl. 1), S317-S318.
Vatn, S. , Carstens, A. , Kristoffersen, A. B. , Bergemalm, D. , Casén, C. , Moen, A. E. F. , Tannaes, T. M. , Lindstrøm, J. & et al. (2020). Faecal microbiota signatures of IBD and their relation to diagnosis, disease phenotype, inflammation, treatment escalation and anti-TNF response in a European Multicentre Study (IBD-Character). Scandinavian Journal of Gastroenterology, 55 (10), 1146-1156.
Halfvarson, J. , Lundström, M. L. , Lampinen, M. , Schoultz, I. , Bodin, L. & Carlson, M. (2020). Genetic and shared environmental risk factors do not lead to eosinophil activation in healthy twins of IBD patients. Scandinavian Journal of Gastroenterology, 55 (10), 1163-1170.
Štambuk, J. , Nakić, N. , Vučković, F. , Pučić-Baković, M. , Razdorov, G. , Trbojević-Akmačić, I. , Novokmet, M. , Keser, T. & et al. (2020). Global variability of the human IgG glycome. Aging, 12 (15), 15222-15259.
Burisch, J. , Eriksson, C. , Halfvarson, J. & Odes, S. (2020). Health-care costs of inflammatory bowel disease in a pan-European, community-based, inception cohort during 5 years of follow-up: a population-based study. The Lancet Gastroenterology & Hepatology, 5 (5), 454-464.
Khalili, H. , Everhov, Å. H. , Halfvarson, J. , Ludvigsson, J. F. , Askling, J. , Myrelid, P. , Söderling, J. , Olen, O. & et al. (2020). Healthcare use, work loss and total costs in incident and prevalent Crohn's disease and ulcerative colitis: results from a nationwide study in Sweden. Alimentary Pharmacology and Therapeutics, 52 (4), 655-668.
Everhov, Å. H. , Erichsen, R. , Sachs, M. C. , Pedersen, L. , Halfvarson, J. , Askling, J. , Ekbom, A. , Ludvigsson, J. F. & et al. (2020). Inflammatory bowel disease and pancreatic cancer: a Scandinavian register-based cohort study 1969-2017. Alimentary Pharmacology and Therapeutics, 52 (1), 143-154.
Axelrad, J. , Olén, O. , Sachs, M. , Erichsen, R. , Pedersen, L. , Halfvarson, J. , Askling, J. , Ekbom, A. & et al. (2020). Inflammatory bowel disease and risk of small bowel cancer: A binational population-based cohort study from Denmark and Sweden. Journal of Crohn's & Colitis, 14 (Suppl. 1), S007-S009.
Fart, F. , Salihovic, S. , McGlinchey, A. J. , Oresic, M. , Halfvarson, J. , Hyötyläinen, T. & Schoultz, I. (2020). Per- and polyfluoroalkyl substances (PFAS) are significantly increased in patients with late-onset of ulcerative colitis. Journal of Crohn's & Colitis, 14 (Suppl. 1), S138-S139.
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Zhulina, Y. , Hahn Strömberg, V. , Shamikh, A. , Gustavsson, A. , Bohr, J. , Nyhlin, N. , Wickbom, A. , Bodin, L. & et al. (2011). NFkB is activated in colonic mucosa of healthy co-twins to twins with inflammatory bowel disease. Gut, 60 (Suppl 3), A290-A290.
Willing, B. P. , Dicksved, J. , Halfvarson, J. , Andersson, A. F. , Lucio, M. , Zheng, Z. , Järnerot, G. , Tysk, C. & et al. (2010). A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes. Gastroenterology, 139 (6), 1844-1854.e1.
Törkvist, L. , Halfvarson, J. , Ong, R. T. H. , Lördal, M. , Sjöqvist, U. , Bresso, F. , Björk, J. , Befrits, R. & et al. (2010). Analysis of 39 Crohn's disease risk loci in Swedish inflammatory bowel disease patients. Inflammatory Bowel Diseases, 16 (6), 907-909.
Halfvarson, J. & Munkholm, P. (2010). Biologics forever. Scandinavian Journal of Gastroenterology, 45, 90-90.
Gustavsson, A. , Järnerot, G. , Hertervig, E. , Friis-Liby, I. , Blomquist, L. , Karlén, P. , Grännö, C. , Vilien, M. & et al. (2010). Clinical trial: colectomy after rescue therapy in ulcerative colitis-3-year follow-up of the Swedish-Danish controlled infliximab study. Alimentary Pharmacology and Therapeutics, 32 (8), 984-989.
Sjöberg, M. , Walch, A. , Meshkat, M. , Gustavsson, A. , Järnerot, G. , Vogelsang, H. , Hertervig, E. , Novacek, G. & et al. (2010). Cyclosporin eller infliximab som rescue terapi vid steroidfraktär ulcerös kolit: en retrospective observationsstudie. Gastrokuriren, 15 (2), 34-34.
McGovern, D. P. B. , Gardet, A. , Törkvist, L. , Goyette, P. , Essers, J. , Taylor, K. D. , Neale, B. M. , Ong, R. T. H. & et al. (2010). Genome-wide association identifies multiple ulcerative colitis susceptibility loci. Nature Genetics, 42 (4), 332-337.
Franke, A. , McGovern, D. P. B. , Barrett, J. C. , Wang, K. , Radford-Smith, G. L. , Ahmad, T. , Lees, C. W. , Balschun, T. & et al. (2010). Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nature Genetics, 42 (12), 1118-1125.
Halfvarson, J. (2010). What determines the disease course, Scandinavian twin data. Scandinavian Journal of Gastroenterology, 45 (S247), 35-36.
Schoultz, I. , Verma, D. , Halfvarson, J. , Törkvist, L. , Fredrikson, M. , Sjöqvist, U. , Lördal, M. , Tysk, C. & et al. (2009). Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men. American Journal of Gastroenterology, 104 (5), 1180-1188.
Grip, O. , Halfvarson, J. , Carlson, M. & Sternby, B. (2009). Diagnosen IBD måste grundas på bred bas: [The diagnosis of IBD must have a wide foundation]. Läkartidningen, 106 (45), 2984-2986.
Kaminsky, Z. A. , Tang, T. , Wang, S. , Ptak, C. , Oh, G. H. T. , Wong, A. H. C. , Feldcamp, L. A. , Virtanen, C. & et al. (2009). DNA methylation profiles in monozygotic and dizygotic twins. Nature Genetics, 41 (2), 240-245.
Einarsdottir, E. , Koskinen, L. L. E. , Dukes, E. , Kainu, K. , Suomela, S. , Lappalainen, M. , Ziberna, F. , Korponay-Szabo, I. R. & et al. (2009). IL23R in the Swedish, Finnish, Hungarian and Italian populations: association with IBD and psoriasis, and linkage to celiac disease. BMC Medical Genetics, 10 (8).
Jansson, J. , Willing, B. , Lucio, M. , Fekete, A. , Dicksved, J. , Halfvarson, J. , Tysk, C. & Schmitt-Kopplin, P. (2009). Metabolomics reveals metabolic biomarkers of Crohn's disease. PloS one, 4 (7), e6386.
Almer, S. , Befrits, R. , Eriksson, A. S. , Halfvarson, J. , Hindorf, U. & Löfberg, R. (2009). Modern läkemedelsterapi vid Crohn [Current drug therapy in Crohn disease]: nationella riktlinjer [national guidelines]. Läkartidningen, 106 (45), 2988-2993.
Zucchelli, M. , Torkvist, L. , Halfvarson, J. , Söderhäll, C. , Lee, Y. , Löfberg, R. , Kere, J. & D ´Amato, M. (2009). No association between the eczema genes COL29A1 and IL31 and inflammatory bowel disease. Inflammatory Bowel Diseases, 15 (7), 961-962.
Zucchelli, M. , Torkvist, L. , Bresso, F. , Halfvarson, J. , Hellquist, A. , Anedda, F. , Assadi, G. , Lindgren, G. B. & et al. (2009). PepT1 oligopeptide transporter (SLC15A1) gene polymorphism in inflammatory bowel disease. Inflammatory Bowel Diseases, 15 (10), 1562-1569.
Verberkmoes, N. C. , Russell, A. L. , Shah, M. , Godzik, A. , Rosenquist, M. , Halfvarson, J. , Lefsrud, M. G. , Apajalahti, J. & et al. (2009). Shotgun metaproteomics of the human distal gut microbiota. The ISME Journal, 3 (2), 179-189.
Zhulina, Y. , Carlson, M. , Peterson, C. G. , Tysk, C. , Gustavsson, A. , Bohr, J. , Bodin, L. & Halfvarson, J. (2009). Subclinical inflammation due to environmental exposure in health co-twins to twins with inflammatory bowel disease. Gastroenterology, 136 (5), A20-A20.
Halfvarson, J. & Järnerot, G. (2009). Treatment of choice for acute severe steroid-refractory ulcerative colitis is remicade. Inflammatory Bowel Diseases, 15 (1), 143-145.
Willing, B. , Halfvarson, J. , Dicksved, J. , Rosenquist, M. , Järnerot, G. , Engstrand, L. , Tysk, C. & Jansson, J. K. (2009). Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohn's disease. Inflammatory Bowel Diseases, 15 (5), 653-660.
Halfvarson, J. , Dicksved, J. , Rosenquist, M. , Willing, E. , Järnerot, G. , Engstrand, L. , Jansson, J. K. & Tysk, C. (2008). Bakteriefloran hos tvillingar med Crohns sjukdom. Gastrokuriren, 13 (29 PO-08).
Gustavsson, A. , Järnerot, G. , Hertervig, E. , Friis-Liby, I. , Blomquist, L. , Karlen, P. , Grännö, C. , Vilien, M. & et al. (2008). Colectomy after rescue therapy for intravenous-steroid resistant acute ulcerative colitis: a 3-year follow-up study of the Swedish-Danish infliximab/placebo trial. Gut, 57(Suppl 1), A79-A79.
Vandewalle-El Khoury, P. , Colombel, J. , Joossens, S. , Standaert-Vitse, A. , Collot, M. , Halfvarson, J. , Ayadi, A. , Landers, C. J. & et al. (2008). Detection of antisynthetic mannoside antibodies (ASigmaMA) reveals heterogeneity in the ASCA response of Crohn's disease patients and contributes to differential diagnosis, stratification, and prediction. American Journal of Gastroenterology, 103 (4), 949-957.
Schoultz, I. , Verma, D. , Törkvist, L. , Halfvarson, J. , Lerm, M. , Söderkvist, P. & Söderholm, J. D. (2008). M2080 Compound Polymorphisms in CARD8 and CIAS1 Predispose to Crohn's Disease in a Swedish Cohort. Gastroenterology, 134 (4), A464-A465.
Dicksved, J. , Halfvarson, J. , Rosenquist, M. , Järnerot, G. , Tysk, C. , Apajalahti, J. , Engstrand, L. & Jansson, J. K. (2008). Molecular analysis of the gut microbiota of identical twins with Crohn's disease. The ISME Journal, 2 (7), 716-727.
Walch, A. , Sjöberg, M. , Meshkat, M. , Gustavsson, A. , Järnerot, G. , Vogelsang, H. , Hertervig, E. , Novacek, G. & et al. (2008). Outcome of rescue therapy in steroid-resistant ulcerative colitis: a retrospective study comparing cyclosporine and infliximab. Gut, 57(Suppl II), A265.
Nyhlin, N. , Bergman, J. , Bohr, J. , Gustavsson, A. , Halfvarson, J. , Salén, E. , Sandberg Gertzén, H. & Tysk, C. (2008). Plasmaferes vid svår läkemedelsutlöst kolestas. Gastrokuriren, 13 (33), PO-16.
Halfvarson, J. , Dicksved, J. , Rosenquist, M. , Järnerot, G. , Tysk, C. , Engstrand, L. & Jansson, J. K. (2008). W1182 molecular fingerprinting of the gut microbiota of twins reveals differences according to Crohn's disease. Gastroenterology, 134 (4, Supplement 1), A-650-A-650.
Gustavsson, A. , Jaenerot, G. , Hertervig, E. , Friis-Iiby, I. , Blomquist, L. , Karlen, P. , Granno, C. , Vilien, M. & et al. (2007). A 2-year follow-up of the swedish-danish Infliximab/Placebo trial in steroid resistant acute ulcerative colitis. Gastroenterology, 132 (4), A146-A147.
Halfvarson, J. , Jess, T. , Bodin, L. , Järnerot, G. , Munkholm, P. , Binder, V. & Tysk, C. (2007). Longitudinal concordance for clinical characteristics in a Swedish-Danish twin population with inflammatory bowel disease. Inflammatory Bowel Diseases, 13 (12), 1536-1544.
Gustavsson, A. , Halfvarson, J. , Magnuson, A. , Sandberg-Gertzén, H. , Tysk, C. & Järnerot, G. (2007). Long-term colectomy rate after intensive intravenous corticosteroid therapy for ulcerative colitis prior to the immunosuppressive treatment era. American Journal of Gastroenterology, 102 (11), 2513-2519.
Järnerot, G. , Halfvarson, J. & Tysk, C. (2007). Twin studies in inflammatory bowel disease: a review. Austral - Asian Journal of Cancer, 6 (1), 29-33.
Bodger, K. , Halfvarson, J. , Dodson, A. R. , Campbell, F. , Wilson, S. , Lee, R. , Lindberg, E. , Järnerot, G. & et al. (2006). Altered colonic glycoprotein expression in unaffected monozygotic twins of inflammatory bowel disease patients. Gut, 55 (7), 973-977.
Halfvarson, J. , Jess, T. , Magnuson, A. , Montgomery, S. M. , Orholm, M. , Tysk, C. , Binder, V. & Järnerot, G. (2006). Environmental factors in inflammatory bowel disease: a co-twin control study of a Swedish-Danish twin population. Inflammatory Bowel Diseases, 12 (10), 925-933.
Halfvarson, J. (2006). Infliximab är indicerat även vid ulcerös kolit. Läkartidningen, 103 (13), 1013-1013.
Järnerot, G. , Halfvarson, J. & Tysk, C. (2006). Twin studies in inflammatory bowel disease: a review. Recent Advances and Research Updates (7), 143-7.
Joossens, S. , Halfvarson, J. , Camps, M. , Vermeire, S. , Jarnerot, G. , Stockbrugger, R. , Bossuyt, X. , Rutgeerts, P. & et al. (2005). A panel of serologic markers in twins with inflammatory bowel disease. Gut (Suppl.).
Halfvarson, J. , Standaert-Vitse, A. , Järnerot, G. , Sendid, B. , Jouault, T. , Bodin, L. , Duhamel, A. , Colombel, J. F. & et al. (2005). Anti-Saccharomyces cerevisiae antibodies in twins with inflammatory bowel disease. Gut, 54 (9), 1237-1243.
Halfvarson, J. , Bresso, F. , D ´Amato, M. , Järnerot, G. , Pettersson, S. & Tysk, C. (2005). CARD15/NOD2 polymorphisms do not explain concordance of Crohn´s disease in Swedish monozygotic twins. Digestive and Liver Disease, 37 (10), 768-762.
Gustavsson, A. , Halfvarson, J. , Tysk, C. & Järnerot, G. (2005). Long-term follow-up study of patients given an intensive intravenous corticosteroid therapy for severe attack of ulcerative colitis. Gut.
Tamboli, C. , Attaluri, A. , Yan, J. , Duke, A. , Colombel, J. F. , Silverberg, M. , McLeod, R. , Jewell, D. & et al. (2005). Phenotypic concordance and time clustering of diagnosis in multiply affected ibd families: the IOIBD Multiplex Family Collaborative Project, phases I & II. Gut, Suppl.
Halfvarson, J. , Jess, T. , Jespersgaard, C. , Riis, L. , Tysk, C. , Järnerot, G. , Skytt Andersen, P. & Munkholm, P. (2005). Prevalence of Toll-like receptor 2 and 4 polymorphisms in twins with inflammatory bowel disease: a population based Danish Swedish cohort study. Gut.
Gustavsson, A. , Halfvarson, J. , Sandberg-Gertzén, H. , Tysk, C. & Järnerot, G. (2005). Tio års uppföljning av patienter behandlade för svår attack av ulcerös kolit. Sv Läkaresällskapets Handl, Hygiea.
Jess, T. , Halfvarson, J. , Bodin, L. , Tysk, C. , Järnerot, G. & Binder, V. (2004). Concordance for Vienna Classification Characteristics in monozygotic twins with Crohn’s disease: a Danish-Swedish cohort study of IBD twins. Gut, 53 (Suppl VI), A140-A140.
Halfvarson, J. , Jess, T. , Bodin, L. , Tysk, C. , Binder, V. & Järnerot, G. (2004). Concordance in phenotype in ulcerative colitis: a study in monozygotic twins. Gut, 53 (Suppl VI), A145-A145.
Halfvarson, J. , Tysk, C. & Jarnerot, G. (2004). Decreasing pair concordance in monozygotic twins with Crohn's disease. Gastroenterology, 126 (4), A45-A45.
Halfvarson, J. , Bresso, F. , Tysk, C. , Pettersson, S. & Jarnerot, G. (2004). Genetic Crohn's disease: A different entity than sporadic. A study in monozygotic twins. Gastroenterology, 126 (4), A359-A360.
Halfvarson, J. , Jess, T. , Bodin, L. , Tysk, C. , Binder, V. & Jarnerot, G. (2004). Phenotypic concordance in monozygotic twin pairs with ulcerative colitis. Gastroenterology, 126 (4), A356-A356.
Jess, T. , Halfvarson, J. , Bodin, L. , Tysk, C. , Jarnerot, G. & Binder, V. (2004). Strong genetic influence on longitudinal changes in Vienna Classification characteristics: a Danish-Swedish cohort study of IBD twins. Gastroenterology, 126 (4), A469-A469.
Halfvarson, J. , Bodin, L. , Tysk, C. , Lindberg, E. & Järnerot, G. (2003). Inflammatory bowel disease in a Swedish twin cohort: a long-term follow-up of concordance and clinical characteristics. Gastroenterology, 124 (7), 1767-1773.
Jess, T. , Halfvarson, J. , Tysk, C. , Binder, V. & Jarnerot, G. (2003). Smoking as a possible explanation for the low concordance among twins with ulcerative colitis: a population based study of environmental factors in a Danish-Swedish twin cohort. Gastroenterology, 124 (4), A205-A205.
Halfvarson, J. (2002). Stor och tung men med bra tangentbord [Big and heavy but the keyboard is good]. Läkartidningen, 99 (13), 1478-1478.
Halfvarson, J. , Heijne, N. , Ljungman, P. , Ham, M. N. , Holmgren, G. & Tomson, G. (2000). Knowing when but not how!: mothers' perceptions and use of antibiotics in a rural area of Viet Nam. Tropical doctor, 30 (1), 6-10.
Halfvarson, J. & Loogna, P. (1997). Svårt avgöra om full och arg har skallskada [Difficult to diagnose head injuries in drunk and violent persons]. Läkartidningen, 94 (42), 3719-3722.

Articles, reviews/surveys

Ludvigsson, J. F. , Andersson, M. , Bengtsson, J. , Eberhardson, M. , Fagerberg, U. L. , Grip, O. , Halfvarson, J. , Hjortswang, H. & et al. (2019). Swedish Inflammatory Bowel Disease Register (SWIBREG): a nationwide quality register. Scandinavian Journal of Gastroenterology, 54 (9), 1089-1101.
Halfvarson, J. , Cummings, F. , Grip, O. & Savoye, G. (2018). Inflammatory bowel disease registries for collection of patient iron parameters in Europe. World Journal of Gastroenterology, 24 (10), 1063-1071.
Ek, W. E. , D'Amato, M. & Halfvarson, J. (2014). The history of genetics in inflammatory bowel disease. Annals of Gastroenterology, 27 (4), 294-303.

Chapters in books

Halfvarson, J. (2013). Genetic epidemiology of inflammatory bowel disease, early twin and family studies. In: D’Amato M, Rioux J., Molecular Genetics of Inflammatory Bowel Disease (pp. 23-43). USA: Springer.
Halfvarson, J. (2009). Ulcerös kolit. In: Utdrag ur Medicinska mag- och tarmsjukdomar. Lund: Studentlitteratur AB.
Halfvarson, J. (2008). Ulcerös kolit. In: Henry Nyhlin, Medicinska mag- och tarmsjukdomar (pp. 371-382). Lund: Studentlitteratur.

Conference papers

Rundquist, S. , Eriksson, C. , Nilsson, L. , Angelison, L. , Jäghult, S. , Björk, J. , Grip, O. , Hjortswang, H. & et al. (2018). Clinical effectiveness of golimumab in Crohn´s disease – an observational study based on the Swedish National Quality Registry for Inflammatory Bowel Disease (SWIBREG). Paper presented at 26th United European Gastroenterology Week, Vienna, Austria, October 20-24, 2018.
Eriksson, C. , Bergenmalm, D. , Vigren, L. , Nilsson, L. , Visuri, I. , Hjortswang, H. , Udumyan, R. , Almer, S. & et al. (2018). Golimumab är effektivt vid ulcerös kolit under svenska förhållanden. Interimsanalys av en svensk prospektiv multi-centerstudie, GO-SWIBREG. Paper presented at Gastrodagarna 2018, Falun, Sweden, 16-18 maj, 2018.
Göranzon, C. , Hultgren Hörnquist, E. , Kumawat, A. K. , Halfvarson, J. , Tysk, C. , Eriksson, S. , Bohr, J. & Nyhlin, N. (2010). Immunohistochemical characterization of lymphocytes in microscopic colitis. Paper presented at 18th United European Gastroenterology Week, Barcelona, Oct, 2010.
Jansson, J. K. , Willing, B. , Dicksved, J. , Halfvarson, J. , Andersson, A. , Rosenquist, M. , Järnerot, G. , Tysk, C. & et al. (2008). Molecular fingerprinting of twins with Crohn's disease reveals the importance of dysbiosis of the gut microbiota. Paper presented at American Society of Microbiology: 2nd conference on beneficial host-microbial interactions, San Diego 12-16 October 2008.
Willing, B. , Halfvarson, J. , Dicksved, J. , Rosenquist, M. , Järnerot, G. , Engstrand, L. , Tysk, C. & Jansson, J. K. (2008). Studying discordant monozygotic twins reveals differences in mucosa-associated microbiota depending on Crohn's disease phenotype. Paper presented at INRA-RRI 2008 Symposium, Clermont-Ferrand, Frankrike, 18-20 Juni, 2008.
Halfvarson, J. , Ahmad, T. , Daperno, M. , Jewell, D. , Järnerot, G. & Tysk, C. (2003). Inflytandet av CARD15/NOD2 samt IBD5 bland svenska tvåäggstvillingar.

Manuscripts

Amcoff, K. , Bergenmalm, D. , Pierik, M. J. , Colombel, J. , Vermeire, S. , Bodin, L. & Halfvarson, J. Environmental and genetic factors in the development of perinuclear-antineutrophil cytoplasmic antibody (pANCA) positive ulcerative colitis : a European twin study.
Carstens, A. , Björkqvist, O. , Lindqvist, C. M. , Rangel, I. , Repsilber, D. , Eriksson, C. , Bergemalm, D. , Bresso, F. & et al. Gut microbiota associated with treatment outcome to biological treatment in inflammatory bowel disease.
Fart, F. , Amcoff, K. , Bergemalm, D. , Andersson, E. , Kalla, R. , Satsangi, J. , Lindqvist, C. M. , Halfvarson, J. & et al. Loss of tolerance to microbial antigens in preclinical Crohn’s disease differs with age at diagnosis : A twin study.
Amcoff, K. , Cao, Y. , Zhulina, Y. , Lampinen, M. , Halfvarson, J. & Carlson, M. Prognostic significance of eosinophile granule proteins in inflammatory bowel disease.
Zhulina, Y. , Cao, Y. , Amcoff, K. , Carlsson, M. , Tysk, C. & Halfvarson, J. Prognostic significance of faecal calprotectin in patients with inactive inflammatory bowel disease.
Melinder, C. , Hiyoshi, A. , Kasiga, T. , Halfvarson, J. , Fall, K. & Montgomery, S. Resilience to stress and risk of gastrointestinal infections.
Gustavsson, A. , Magnuson, A. , Blomberg, B. , Andersson, M. , Halfvarson, J. & Tysk, C. Smoking is a risk factor for recurrence of intestinal stricture after endoscopic dilation in Crohn’s disease.