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Research Projects

Epidemiology and Genetic epidemiology

About this project

About this project

Project information

Projekt Status

In progress

Contact

Jonas Halfvarson

Research Subject

Epidemiology may be used as an instrument to characterize mechanisms related to the pathogenesis of complex diseases such as Inflammatory Bowel Diseases (IBD). We have a long history of long of epidemiological studies. At present two PhD projects are exploring temporal trends in the epidemiology of IBD.

Twin studies provide a powerful tool to disentangle the relative contribution of genetics and environmental factors in the aetiology of IBD. Monozygotic twins are genetically identical, share intrauterine environment and to a high extent other, but necessarily not all, external factors during childhood. Dizygotic twins share environment to the same extent as monozygotic pairs but, on average, only half of the genes. Based on our twin cohort we have a number of different projects that focus on the interaction between the environment and the genetic predisposition in IBD.

Researchers

Research Teams

Collaborators

  • Arturas Petronis, University of Toronto, Toronto, Ontario
  • Johan Dabrosin Söderholm, Linköping universitet
  • Severine Vermeire, Katolische Universitet, Leuven
  • The Swedish Organisation for studies of Inflammatory Bowel Diseases (SOIBD)s,