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Maria Lodefalk

Title: Affiliated Researcher School/office: School of Medical Sciences

Email: maria.lodefalk@oru.se

Phone: +46 19 303000

Room: -

Research subject

Medicine

Research environments

Diabetes, Endocrinology and Metabolism Research Centre

About Maria Lodefalk

Maria Lodefalk is a paediatrician, working as a consultant at the Paediatric Department, Örebro University Hospital, and an affiliated researcher at the Faculty of Medicine and Health, Örebro University. She defended her thesis on food habits and gastrointestinal function in adolescents with type 1 diabetes at the Karolinska Institutet, Stockholm, in 2009. Since November 2021, Maria Lodefalk has been a docent at the department. Her present research focuses on both paediatric endocrinology and molecular biological changes in human placenta in relation to maternal, foetal and neonatal characteristics. Lodefalk is responsible for a large sample collection of placenta and cord blood samples, which has given rise to one thesis, so far.

Maria Lodefalk is involved in the Medical Programme and the Specialist Nurse Programme at Örebro University, is a member of a national working group on growth disorders in children and co-supervisor to several Ph.D. students.

More information about the placenta and cord blood sample collection at Örebro University Hospital, Örebro, Sweden

Completed projects

Research teams

Publications

Articles in journals

Rodanaki, M. , Rask, E. & Lodefalk, M. (2022). A Randomized Trial of the Effect of a GnRH Analogue Injection on Ghrelin Levels in Girls. Hormone Research in Paediatrics, 95 (5), 442-451.
Rodanaki, M. , Rask, E. & Lodefalk, M. (2022). Delayed puberty in boys in central Sweden: an observational study on diagnosing and management in clinical practice. BMJ Open, 12 (2).
Lodefalk, M. , Allbrand, M. & Montgomery, S. (2022). Duration of the pushing phase of labor is inversely associated with expression of TNF, IL6, IGF1 and IGF2 in human placenta. The Journal of Maternal-Fetal & Neonatal Medicine, 35 (25), 6476-6482.
Allbrand, M. , Eklund, D. , Cao, Y. , Nilsson, K. & Lodefalk, M. (2022). Gene expression of leptin, leptin receptor isoforms and inflammatory cytokines in placentas of obese women: Associations to birth weight and fetal sex. Placenta, 117, 64-71.
Östling, H. , Lodefalk, M. , Backman, H. & Kruse, R. (2022). Global microRNA and protein expression in human term placenta. Frontiers in Medicine, 9.
Östling, H. , Lodefalk, M. , Backman, H. & Kruse, R. (2022). Global microRNA and protein expression in human term placenta may improve our understanding of fetal growth. Hormone Research in Paediatrics, 95 (Suppl. 2), 247-247.
Östling, H. , Lodefalk, M. , Backman, H. & Kruse, R. (2022). Global microRNA and protein expression in humanterm placenta may improve our understandingof fetal growth. Hormone Research in Paediatrics, 95 (2), 247-247.
Rodanaki, M. , Rask, E. & Lodefalk, M. (2022). The effect of a GnRH analogue injection on the circulating levels of kisspeptin-1 in girls with suspected central precocious puberty. Hormone Research in Paediatrics, 95 (Suppl. 2), 341-341.
Rodanaki, M. , Rask, E. & Lodefalk, M. (2022). The effect of a GnRH analogue injection on thecirculating levels of kisspeptin-1 in girls withsuspected central precocious puberty. Hormone Research in Paediatrics, 95 (Sup. 2), 341-341.
Rodanaki, M. , Rask, E. & Lodefalk, M. (2021). Adding a protease inhibitor to sampling tubes increases the acylated ghrelin and decreases the desacylated ghrelin levels in girls. Hormone Research in Paediatrics, 94 (Suppl. 1), 111-112.
Lennartsson, O. , Lodefalk, M. , Wehtje, H. , Stattin, E. , Sävendahl, L. & Nilsson, O. (2021). Case Report: Bilateral Epiphysiodesis Due to Extreme Tall Stature in a Girl With a De Novo DNMT3A Variant Associated With Tatton-Brown-Rahman Syndrome. Frontiers in Endocrinology, 12.
Roxenlund, F. , Kruse, R. , Östling, H. & Lodefalk, M. (2021). Differential microRNA expression in placentas of small-for-gestational age neonates with and without exposure to poor maternal gestational weight gain. Journal of Perinatal Medicine, 49 (5), 632-635.
Lennartsson, O. & Lodefalk, M. (2021). Stor diskrepans mellan olika test vid utredning av kortvuxna barn. Läkartidningen, 8.
Hoermann, H. , El-Rifai, O. , Schebek, M. , Lodefalk, M. , Brusgaard, K. , Bachmann, N. , Bergmann, C. , Roeper, M. & et al. (2020). Comparative meta-analysis of Kabuki syndrome with and without hyperinsulinemic hypoglycemia. Clinical Endocrinology, 93 (3), 346-354.
Lennartsson, O. , Nilsson, O. & Lodefalk, M. (2020). Discordance Between Stimulated and Spontaneous Growth Hormone Levels in Short Children Is Dependent on Cut-Off Level and Partly Explained by Refractoriness. Frontiers in Endocrinology, 11.
Allbrand, M. , Åman, J. , Nilsson, K. , Cao, Y. & Lodefalk, M. (2019). Expression of genes involved in inflammation and growth: does sampling site in human full-term placenta matter?. Journal of Perinatal Medicine, 47 (5), 539-546.
Östling, H. , Kruse, R. , Helenius, G. & Lodefalk, M. (2019). Placental expression of microRNAs in infants born small for gestational age. Placenta, 81, 46-53.
Rodanaki, M. , Lodefalk, M. , Forssell, K. , Arvidsson, C. , Forssberg, M. & Åman, J. (2019). The Incidence of Childhood Thyrotoxicosis Is Increasing in Both Girls and Boys in Sweden. Hormone Research in Paediatrics, 91 (3), 195-202.
Rodanaki, M. , Lodefalk, M. & Åman, J. (2018). Incidence and Treatment Outcome of Childhood Thyrotoxicosis. Hormone Research in Paediatrics, 90 (Suppl.1), 90-91.
Rodanaki, M. , Rask, E. & Lodefalk, M. (2018). Incidence of Delayed Puberty in Adolescents: A Population-Based Study in a County in Central Sweden. Hormone Research in Paediatrics, 90 (Suppl.1), 510-510.
Östling, H. , Kruse, R. , Helenius, G. & Lodefalk, M. (2017). Infants born small-for-gestational age have different placental expression of microRNAs. Hormone Research in Paediatrics, 88 (Suppl. 1), 100-101.
Allbrand, M. , Åman, J. & Lodefalk, M. (2017). Placental ghrelin and leptin expression and cord blood ghrelin, adiponectin, leptin, and C-peptide levels in severe maternal obesity. The Journal of Maternal-Fetal & Neonatal Medicine, 31 (21), 2839-2846.
Lodefalk, M. & Nilsson, O. (2017). To Prime or Not to Prime - Is That Still a Question?: A Comment on the US Guidelines on Growth Hormone and Insulin-Like Growth Factor-I Treatment in Children and Adolescents. Hormone Research in Paediatrics, 88 (2), 179-180.
Lodefalk, M. , Frykholm, C. , Esbjörner, E. & Ljunggren, Ö. (2016). Hypercalcaemia in a Patient with 2p13.2-p16.1 Duplication. Hormone Research in Paediatrics, 85 (3), 213-218.
Allbrand, M. , Åman, J. & Lodefalk, M. (2015). Adipocytokines in placenta and cord blood in relation to maternal obesity, and foetal and postnatal growth of the child. Hormone Research in Paediatrics, 82 (Suppl. 1), 47-48.
Lodefalk, M. , Carlsson-Skwirut, C. , Holst, J. J. , Aman, J. & Bang, P. (2010). Effects of fat supplementation on postprandial GIP, GLP-1, ghrelin and IGFBP-1 levels: a pilot study on adolescents with type 1 diabetes. Hormone Research in Paediatrics, 73 (5), 355-62.
Lodefalk, M. & Åman, J. (2010). Gastrointestinal symptoms in adolescents with type 1 diabetes. Pediatric Diabetes, 11 (4), 265-70.
Lodefalk, M. , Åman, J. & Bang, P. (2008). Effects of fat supplementation on glycaemic response and gastric emptying in adolescents with Type 1 diabetes. Diabetic Medicine, 25 (9), 1030-1035.
Lodefalk, M. & Åman, J. (2006). Food habits, energy and nutrient intake in adolescents with Type 1 diabetes mellitus. Diabetic Medicine, 23 (11), 1225-1232.
[Svensson] Lodefalk, M. , Engström, I. & Åman, J. (2003). Higher drive for thinness in adolescent males with insulin-dependent diabetes mellitus compared with healthy controls. Acta Paediatrica, 92, 114-117.

Chapters in books

Samuelson, G. , Åman, J. , Lodefalk, M. , Detlofsson, I. , Cederholm, U. & Vall, H. (2008). Mat vid diabetes. In: Sture Sjöblad, Barn- och ungdomsdiabetes (pp. 93-101). Lund: Studentlitteratur.

Conference papers

Hoermann, H. , El-Rifai, O. , Schebek, M. , Lodefalk, M. , Brusgaard, K. , Bachmann, N. , Bergmann, C. , Mayatepek, E. & et al. (2019). Characteristics of children with Kabuki syndrome and hyperinsulinemic hypoglycemia. Paper presented at The 58th Annual European Society For Paediatric Endocrinology Meeting, 2019, Vienna, Austria, 19-21 September, 2019.

Doctoral theses, comprehensive summaries

Lodefalk, M. (2009). Adolescent type 1 diabetes: Eating and gastrointestinal function. (Doctoral dissertation). (Comprehensive summary) Stockholm: Karolinska Institutet.

Manuscripts

Allbrand, M. , Eklund, D. , Cao, Y. , Åman, J. , Nilsson, K. & Lodefalk, M. Gene expression of leptin, leptin receptor isoforms, and inflammatory cytokines in placentas of obese women : associations to birth weight and foetal sex.