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Victor Castro Alves

Title: Researcher School/office: School of Science and Technology


Phone: +46 19 303819

Room: B3118

Victor Castro Alves
Research subject Research environments

About Victor Castro Alves

Victor Castro-Alves started at Örebro University as a postdoc in 2019 within the multidisciplinary Food and Health strategic research initiative and since 2021 is a researcher at the Man-Technology-Environment Research Centre, School of Science and Technology, ORU.


Research interests

My research is focused mainly on the development, application and optimization of mass spectrometry-based pipelines to explore the interplay between food composition, nutrition and human health.

Below you will find more information about some of our projects:


1. ImprUVing the quality of greenhouse of greenhouse crops 


In ImprUV - Increasing sensory quality and content of health-promoting components in vegetables and herbs, we are applying the cutting-edge concept of sensomics, which integrates metabolomics, the comprehensive analysis of all metabolites in a studied biological system, with highly innovative testing for culinary quality and plant production parameters in collaboration with national and international research groups as well with commercial producers. We are also exploring how changes in plant production impact the synthesis of health-promoting compounds in plants and how these metabolites are biotransformed by the human gut microbiota and induce biological effects by using in vitro colonic fermentation studies and reporter cell assays. Our approach aims not only the production of healthier and tastier foods in a climate-smart way but also to contribute to the basic understanding of the relationship between plant metabolism and potential effects on human health. That will lead to practical applications that will benefit primary producers, retailers, and, first and foremost, consumers.

You are welcome to check out our most recent preprint "From Farm to Fork… and Beyond: UV Enhances Aryl Hydrocarbon Receptor-Mediated Activity of Cruciferous Vegetables in Human Intestinal Cells Upon Colonic Fermentation"


2. Unpuzzling the structure and health effects of dietary fibers 


Victor coordinates the project Unpuzzle - Unravelling molecular motifs of dietary fibers responsible for interaction with receptors in human cells, funded both by a Starting Grant from the Swedish Research Council (VR) and by the Lantmännen Research Foundation.

Dietary fibres (DF) from foods can induce beneficial health effects by interacting with receptors at the surface of intestinal epithelial cells and immune system cells. Although the knowledge of the structure-function relationship between DF and their biological effects in human cells is highly desirable for successful translational applications, the molecular motifs within (the often complex) DF structure responsible for interaction with human cells remain poorly understood. In Unpuzzle, we propose a new methodological framework to explore the interaction between DF and human cell receptors. We will reduce the structural complexity of selected DF by generating oligomers (structural motifs) that will be further fractionated, characterized through mass-spectrometry approaches and evaluated both for interaction with receptors in human cells and for biological effects in human intestinal and immune cells through metabolomics-based approaches and cytokine array. In addition, to provide novel information about the effects of DF on gut health, we will also produce information for identifying and tailoring DF with desired biological effects.


Teaching and supervision

Victor is the course coordinator of Instrumental Analytical Methods in the Chemistry program and is involved in the Analytical chemistry course. He is also a lecturer in the Biology program and has been involved in the international master's programs of Environmental Forensics (School of Science and Technology) and Translational Medicine (School of Medical Sciences). He supervise students in the Chemistry program and incoming exchange students from bachelor, master and PhD level. Financial support for the incoming students was obtained mainly through Erasmus+ program, São Paulo Research Foundation and German Academic Exchange Service (DAAD).


Other activities

Victor is a member of the Editorial Board of Frontiers in Nutrition and Frontiers in Sustainable Food Systems. In addition, he has been actively participating in internationalization efforts on different levels, planning student exchange with partners within the NEOLAiA program, participating in research exchange within MIRAI 2.0, as well as being part of the EIRENE PPP work group at ORU.


For more information about published papers please refer to my ResearcherID and Google Scholar. You can also find me on ResearchGate and Twitter.


Articles in journals |  Articles, reviews/surveys |  Chapters in books | 

Articles in journals

Articles, reviews/surveys

Chapters in books