Anna Kärrman
Title: Senior Lecturer School/office: School of Science and Technology
Email:
Phone: +46 19 301401
Room: B3315
About Anna Kärrman
Anna Kärrman is deputy head of School of Science and Technology and associate professor (docent) in environmental chemistry conducting research in the Environment and Health group at MTM Research Centre.
Research
Anna Kärrman’s main research agenda is to unravel the identity of drivers of toxicity by seeking relevant and sensitive methods including non-targeted methodologies. Focus is on analytical chemistry and emerging organic pollutants, their distribution in the environment, sources, and human exposure. Among her research work are studies of per- and polyfluoroalkyl substances and microplastics. Most of her work is conducted within the Environmental Forensic Laboratory (EnForce), of which she is the deputy manager. Among her external assignments are the Swedish Chemical Society editorial board and The Toxicological Council, the latter an expert group acting as an early warning system for the identification of chemical substances that can be harmful to human health or the environment.
Research Projects
Research Projects
- A pilot study on unidentified poly- and perfluoroalkyl substances (PFASs) in sewage in Sweden
- A temporal study on unidentified poly- and perfluoroalkyl substances (PFASs) in sewage sludge in Sweden
- Baltic Sea Expedition 2014
- Biomonitoring PFAS in Sweden
- Exponering av föregångarämnen till PFAS
- Infant's exposure for environmental pollutants
- UN global monitoring of PFAS in human milk
- Occurrence of microplastics in Swedish lakes
- Global Monitoring Plan on Persistent Organic Pollutants
- Are humans and the environment exposed to increasing amounts of unknown highly fluorinated substances?
- Identification of unknown pollutants
- Implementation of a novel approach for identifying unknown potentially harmful substances in dust
- Plastic pollution - chemical risks for marine ecosystems
- Miljöneutrala brandsläckningsmetodiker
- Mixture-Risk
- PAC-Risk
- Effects of perfluoroalkyl and polyfluoroalkyl substances on metabolic pathways studied in an avian embryo model
- PFAS-Risk
- PLASTIC-Risk
- Screening of total organofluorine substances (TOF) and emerging PFASs in the Swedish environment
- Screening of PFAS and total organic fluorine (TOF) in Nordic Countries
- Environmental and health effects of fire fighting foams
- Ultra-short-chain perfluoroalkyl substances (PFASs) in the Swedish environment - an unknown environmental threat?
- Transfer of per- and polyfluoroalkyl substances from the aquatic environment to the terrestrial ecosystem: mechanisms and ecological effects
Research Teams
Research Teams
Publications
Publications
Articles in journals |
Articles, reviews/surveys |
Chapters in books |
Conference papers |
Doctoral theses, comprehensive summaries |
Manuscripts |
Reports |
Articles in journals
Yukioka, S. , Tanaka, S. , Suzuki, Y. , Echigo, S. , Kärrman, A.
& Fujii, S. (2020). A profile analysis with suspect screening of per- and polyfluoroalkyl substances (PFASs) in firefighting foam impacted waters in Okinawa, Japan. Water Research, 184.
Dubocq, F. , Wang, T. , Yeung, L. W. Y. , Sjöberg, V.
& Kärrman, A. (2020). Characterization of the Chemical Contents of Fluorinated and Fluorine-Free Firefighting Foams Using a Novel Workflow Combining Nontarget Screening and Total Fluorine Analysis. Environmental Science and Technology, 54 (1), 245-254.
Karlsson, T. M. , Kärrman, A. , Rotander, A.
& Hassellöv, M. (2020). Comparison between manta trawl and in situ pump filtration methods, and guidance for visual identification of microplastics in surface waters. Environmental Science and Pollution Research, 27 (5), 5559-5571.
Schönlau, C. , Karlsson, T. M. , Rotander, A. , Nilsson, H. , Engwall, M. , van Bavel, B.
& Kärrman, A. (2020). Microplastics in sea-surface waters surrounding Sweden sampled by manta trawl and in-situ pump. Marine Pollution Bulletin, 153.
Dubocq, F. , Bjurlid, F. , Ydstål, D. , Titaley, I. A. , Reiner, E. , Wang, T. , Almirall, X. O.
& Kärrman, A. (2020). Organic contaminants formed during fire extinguishing using different firefighting methods assessed by nontarget analysis. Environmental Pollution, 265.
Schönlau, C. , Larsson, M. , Lam, M. M. , Engwall, M. , Giesy, J. P. , Rochman, C.
& Kärrman, A. (2019). Aryl hydrocarbon receptor-mediated potencies in field-deployed plastics vary by type of polymer. Environmental Science and Pollution Research, 26 (9), 9097-9088.
Lind, P. M. , Salihovic, S. , Stubleski, J. , Kärrman, A.
& Lind, L. (2019). Association of Exposure to Persistent Organic Pollutants With Mortality Risk: An Analysis of Data From the Prospective Investigation of Vasculature in Uppsala Seniors (PIVUS) Study. JAMA network open, 2 (4).
Mattsson, A. , Sjöberg, S. , Kärrman, A.
& Brunström, B. (2019). Developmental exposure to a mixture of perfluoroalkyl acids (PFAAs) affects the thyroid hormone system and the bursa of Fabricius in the chicken. Scientific Reports, 9 (1).
Schönlau, C. , Larsson, M. , Dubocq, F. , Rotander, A. , Van der Zande, R. , Engwall, M.
& Kärrman, A. (2019). Effect-Directed Analysis of Ah Receptor-Mediated Potencies in Microplastics Deployed in a Remote Tropical Marine Environment. Frontiers in Environmental Science, 7.
Salihovic, S. , Fall, T. , Ganna, A. , Broeckling, C. D. , Prenni, J. E. , Hyötyläinen, T. , Kärrman, A. , Lind, P. M.
& et al.
(2019). Identification of metabolic profiles associated with human exposure to perfluoroalkyl substances. Journal of Exposure Science and Environmental Epidemiology, 29 (2), 196-205.
Koch, A. , Kärrman, A. , Yeung, L. W. Y. , Jonsson, M. , Ahrens, L.
& Wang, T. (2019). Point source characterization of per- and polyfluoroalkyl substances (PFASs) and extractable organofluorine (EOF) in freshwater and aquatic invertebrates. Environmental Science: Processes & Impacts, 21 (11), 1887-1898.
Björnsdotter, M. , Yeung, L. W. Y. , Kärrman, A.
& Ericson Jogsten, I. (2019). Ultra-Short-Chain Perfluoroalkyl Acids Including Trifluoromethane Sulfonic Acid in Water Connected to Known and Suspected Point Sources in Sweden. Environmental Science and Technology, 53 (19), 11093-11101.
Stubleski, J. , Kukucka, P. , Salihovic, S. , Lind, P. M. , Lind, L.
& Kärrman, A. (2018). A method for analysis of marker persistent organic pollutants in low-volume plasma and serum samples using 96-well plate solid phase extraction. Journal of Chromatography A, 1546, 18-27.
Salihovic, S. , Stubleski, J. , Kärrman, A. , Larsson, A. , Fall, T. , Lind, L.
& Lind, P. M. (2018). Changes in markers of liver function in relation to changes in perfluoroalkyl substances: A longitudinal study. Environment International, 117, 196-203.
Lind, P. M. , Salihovic, S. , Stubleski, J. , Kärrman, A.
& Lind, L. (2018). Changes in plasma levels of perfluoroalkyl substances (PFASs) are related to increase in carotid intima-media thickness over 10 years - a longitudinal study. Environmental health, 17.
Stubleski, J. , Lind, L. , Salihovic, S. , Lind, P. M.
& Kärrman, A. (2018). Longitudinal changes in persistent organic pollutants (POPs) from 2001 to 2009 in a sample of elderly Swedish men and women. Environmental Research, 165, 193-200.
Eriksson, U. , Haglund, P.
& Kärrman, A. (2017). Contribution of precursor compounds to the release of per- and polyfluoroalkyl substances (PFASs) from waste water treatment plants (WWTPs). Journal of Environmental Sciences(China), 61, 80-90.
Blanc, M. , Kärrman, A. , Kukučka, P. , Scherbak, N.
& Keiter, S. (2017). Mixture-specific gene expression in zebrafish (Danio rerio) embryos exposed to perfluorooctane sulfonic acid (PFOS), perfluorohexanoic acid (PFHxA) and 3,3′,4,4′,5-pentachlorobiphenyl (PCB126). Science of the Total Environment, 590-591, 249-257.
Bjurlid, F. , Kärrman, A. , Ricklund, N.
& Hagberg, J. (2017). Occurrence of brominated dioxins in a study using various firefighting methods. Science of the Total Environment, 599-600, 1213-1221.
Eriksson, U. , Mueller, J. F. , Toms, L. L. , Hobson, P.
& Kärrman, A. (2017). Temporal trends of PFSAs, PFCAs and selected precursors in Australian serum from 2002 to 2013. Environmental Pollution, 220 (Pt A), 168-177.
Lind, M. , Salihovic, S. , Stubleski, J. , Kärrman, A. , van Bavel, B.
& Lind, L. (2017). The changes in plasma levels of perfluoroalkyl substances (PFASs) are related to the increase in carotid intima-media thickness over 10 years. Atherosclerosis, 263, E18-E18.
Stubleski, J. , Salihovic, S. , Lind, P. M. , Lind, L. , Dunder, L. , McCleaf, P. , Eurén, K. , Ahrens, L.
& et al.
(2017). The effect of drinking water contaminated with perfluoroalkyl substances on a 10-year longitudinal trend of plasma levels in an elderly Uppsala cohort. Environmental Research, 159, 95-102.
Stubleski, J. , Salihovic, S. , Lind, L. , Lind, P. M. , van Bavel, B.
& Kärrman, A. (2016). Changes in serum levels of perfluoroalkyl substances during a 10-year follow-up period in a large population-based cohort. Environment International, 95, 86-92.
Eriksson, U. , Roos, A. , Lind, Y. , Hope, K. , Ekblad, A.
& Kärrman, A. (2016). Comparison of PFASs contamination in the freshwater and terrestrial environments by analysis of eggs from osprey (Pandion haliaetus), tawny owl (Strix aluco), and common kestrel (Falco tinnunculus). Environmental Research, 149, 40-47.
Mattsson, A. , Kärrman, A. , Pinto, R.
& Brunström, B. (2015). Metabolic Profiling of Chicken Embryos Exposed to Perfluorooctanoic Acid ( PFOA) and Agonists to Peroxisome Proliferator-Activated Receptors. PLoS ONE, 10 (12).
Rotander, A. , Kärrman, A. , Toms, L. L. , Kay, M. , Mueller, J. F.
& Gómez Ramos, M. J. (2015). Novel fluorinated surfactants tentatively identified in firefighters using liquid chromatography quadrupole time-of-flight tandem mass spectrometry and a case-control approach. Environmental Science and Technology, 49 (4), 2434-2442.
Salihovic, S. , Kärrman, A. , Lind, L. , Lind, P. M. , Lindström, G.
& van Bavel, B. (2015). Perfluoroalkyl substances (PFAS) including structural PFOS isomers in plasma from elderly men and women from Sweden: Results from the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS). Environment International, 82 (Sept 2015), 21-27.
Eriksson, U.
& Kärrman, A. (2015). World-Wide Indoor Exposure to Polyfluoroalkyl Phosphate Esters (PAPs) and other PFASs in Household Dust. Environmental Science and Technology, 49 (24), 14503-14511.
Hardell, E. , Kärrman, A. , van Bavel, B. , Bao, J. , Carlberg, M.
& Hardell, L. (2014). Case-control study on perfluorinated alkyl acids (PFAAs) and the risk of prostate cancer. Environment International, 63, 35-39.
Kärrman, A. , Ericson Jogsten, I. , Davies, J. , van Bavel, B. , Holsen, A. H.
& Laugesen, J. (2014). Per- and polyfluoroalkyl substances in effluents from hazardous waste treatment facilities. Organohalogen Compounds, 76.
Bao, J. , Kärrman, A. , van Bavel, B.
& Jin, Y. (2014). Perfluoroalkyl substances in the blood samples from a male population of Sweden. Chinese Science Bulletin, 59 (4), 388-395.
Salihovic, S. , Kärrman, A. , Lindström, G. , Lind, P. M. , Lind, L.
& van Bavel, B. (2013). A rapid method for the determination of perfluoroalkyl substances including structural isomers of perfluorooctane sulfonic acid in human serum using 96-well plates and column-switching ultra-high performance liquid chromatography tandem mass spectrometry. Journal of Chromatography A, 1305, 164-170.
Nilsson, H. , Kärrman, A. , Rotander, A. , van Bavel, B. , Lindström, G.
& Westberg, H. (2013). Biotransformation of fluorotelomer compound to perfluorocarboxylates in humans. Environment International, 51, 8-12.
Persson, S. , Rotander, A. , Kärrman, A. , van Bavel, B.
& Magnusson, U. (2013). Perfluoroalkyl acids in subarctic wild male mink (Neovison vison) in relation to age, season and geographical area. Environment International, 59, 425-430.
Eriksson, U. , Kärrman, A. , Rotander, A. , Mikkelsen, B.
& Dam, M. (2013). Perfluoroalkyl substances (PFASs) in food and water from Faroe Islands. Environmental Science and Pollution Research, 20 (11), 7940-7948.
Nilsson, H. , Kärrman, A. , Rotander, A. , van Bavel, B. , Lindström, G.
& Westberg, H. (2013). Professional ski waxers' exposure to PFAS and aerosol concentrations in gas phase and different particle size fractions. Environmental science. Processes & impacts, 15 (4), 814-822.
Kärrman, A.
& Lindström, G. (2013). Trends, analytical methods and precision in the determination of perfluoroalkyl acids in human milk. TrAC. Trends in analytical chemistry, 46, 118-128.
Domingo, J. L. , Ericson-Jogsten, I. , Perello, G. , Nadal, M. , van Bavel, B.
& Kärrman, A. (2012). Human exposure to perfluorinated compounds in Catalonia, Spain: contribution of drinking water and fish and shellfish. Journal of Agricultural and Food Chemistry, 60 (17), 4408-4415.
Rotander, A. , Kärrman, A. , van Bavel, B. , Polder, A. , Riget, F. , Atli Auounsson, G. , Vikingsson, G. , Wing Gabrielsen, G.
& et al.
(2012). Increasing levels of long-chain perfluorocarboxylic acids (PFCAs) in Arctic and North Atlantic marine mammals, 1984-2009. Chemosphere, 86 (3), 278-285.
Strömqvist, M. , Olsson, J. A. , Kärrman, A.
& Brunström, B. (2012). Transcription of genes involved in fat metabolism in chicken embryos exposed to the peroxisome proliferator-activated receptor alpha (PPAR alpha) agonist GW7647 or to perfluorooctane sulfonate (PFOS) or perfluorooctanoic acid (PFOA). Comparative Biochemistry and Physiology - Part C: Toxicology & Pharmacology, 156 (1), 29-36.
Kärrman, A. , Elgh-Dalgren, K. , Lafossas, C.
& Moskeland, T. (2011). Environmental levels and distribution of structural isomers of perfluoroalkyl acids after aqueous fire-fighting foam (AFFF) contamination. Environmental Chemistry, 8 (4), 372-380.
Berger, U. , Kaiser, M. A. , Kärrman, A. , Barber, J. L.
& van Leeuwen, S. P. J. (2011). Recent developments in trace analysis of poly- and perfluoroalkyl substances. Analytical and Bioanalytical Chemistry, 400 (6), 1625-1635.
Nilsson, H. , Kärrman, A. , Westberg, H. , Rotander, A. , van Bavel, B.
& Lindström, G. (2010). A time trend study of significantly elevated perfluorocarboxylate levels in humans after using fluorinated ski wax. Environmental Science and Technology, 44 (6), 2150-2155.
Kärrman, A. , Domingo, J. L. , Llebaria, X. , Nadal, M. , Bigas, E. , van Bavel, B.
& Lindström, G. (2010). Biomonitoring perfluorinated compounds in Catalonia, Spain: concentrations and trends in human liver and milk samples. Environmental Science and Pollution Research, 17 (3), 750-758.
Nilsson, H. , Kärrman, A. , Rotander, A. , van Bavel, B. , Lindström, G.
& Westberg, H. (2010). Inhalation exposure to fluorotelomer alcohols yield perfluorocarboxylates in human blood?. Environmental Science and Technology, 44 (19), 7717-7722.
Minata, M. , Harada, K. H. , Kärrman, A. , Hitomi, T. , Hirosawa, M. , Murata, M. , Gonzalez, F. J.
& Koizumi, A. (2010). Role of Peroxisome Proliferator-activated Receptor-alpha in Hepatobiliary Injury Induced by Ammonium Perfluorooctanoate in Mouse Liver. Industrial Health, 48 (1), 96-107.
Lindström, G. , Kärrman, A.
& van Bavel, B. (2009). Accuracy and precision in the determination of perfluorinated chemicals in human blood verified by interlaboratory comparisons. Journal of Chromatography A, 1216 (3), 394-400.
Ericson Jogsten, I. , Perelló, G. , Llebaria, X. , Bigas, E. , Martí-Cid, R. , Kärrman, A.
& Domingo, J. L. (2009). Exposure to perfluorinated compounds in Catalonia, Spain, through consumption of various raw and cooked foodstuffs, including packaged food. Food and Chemical Toxicology, 47 (7), 1577-1583.
Mahmoud, M. A. M. , Kärrman, A. , Oono, S. , Harada, K. H.
& Koizumi, A. (2009). Polyfluorinated telomers in precipitation and surface water in an urban area of Japan. Chemosphere, 74 (3), 467-472.
Kärrman, A. , Harada, K. H. , Inoue, K. , Takasuga, T. , Ohi, E.
& Koizumi, A. (2009). Relationship between dietary exposure and serum perfluorochemical (PFC) levels-A case study. Environment International, 35 (4), 712-717.
Kärrman, A. , Ericson Jogsten, I. , van Bavel, B. , Darnerud, P. O. , Aune, M. , Glynn, A. , Lignell, S.
& Lindström, G. (2007). Exposure of perfluorinated chemicals through lactation: levels of matched human milk and serum and a temporal trend, 1996-2004, in Sweden. Environmental Health Perspectives, 115 (2), 226-230.
Kärrman, A. , Langlois, I. , van Bavel, B. , Lindström, G.
& Oehme, M. (2007). Identification and pattern of perfluorooctane sulfonate (PFOS) isomers in human serum and plasma. Environment International, 33 (6), 782-788.
Kärrman, A. , Mueller, J. F. , van Bavel, B. , Harden, F. , Toms, L. L.
& Lindström, G. (2006). Levels of 12 perfluorinated chemicals in pooled Australian serum, collected 2002-2003, in relation to age, gender, and region. Environmental Science and Technology, 40 (12), 3742-3748.
Kärrman, A. , van Bavel, B. , Järnberg, U. , Hardell, L.
& Lindström, G. (2006). Perfluorinated chemicals in relation to other persistent organic pollutants in human blood. Chemosphere, 64 (9), 1582-1591.
van Leeuwen, S. P. J. , Kärrman, A. , van Bavel, B. , de Boer, J.
& Lindström, G. (2006). Struggle for quality in determination of perfluorinated contaminants in environmental and human samples. Environmental Science and Technology, 40 (24), 7854-7860.
Kärrman, A. , van Bavel, B. , Järnberg, U. , Hardell, L.
& Lindström, G. (2005). Development of a solid-phase extraction-HPLC/Single quadrupole MS method for quantification of perfluorochemicals in whole blood. Analytical Chemistry, 77 (3), 864-870.
Martin, J. , Kannan, K. , Berger, U. , de Voogt, P. , Field, J. , Franklin, J. , Giesy, J. , Harner, T.
& et al.
(2004). Analytical challenges hamper perfluoroalkyl research. Environmental Science and Technology, 38 (13), 248A-255A.
Articles, reviews/surveys
Björnsdotter, M. , Yeung, L. W. Y. , Kärrman, A.
& Ericson Jogsten, I. (2020). Challenges in the analytical determination of ultra-short-chain perfluoroalkyl acids and implications for environmental and human health. Analytical and Bioanalytical Chemistry.
Chapters in books
Kärrman, A. , Parera, J. , Abalos, M. , Van Bavel, B.
& Abad, E. (2012). Assessing and controlling sample contamination: analytical techniques for scientists.
In:
Janusz Pawliszyn, Comprehensive sampling and sample preparation (pp. 51-64).
Oxford UK: Elsevier.
Conference papers
Li, Y. , Hagberg, J. , Kärrman, A. , Bao, J. , Zhang, Q. , Jiang, G.
& van Bavel, B. (2012). Occurence of perfluorinated compounds in marine fish, Antarctica.
In:
Organohalogen Compounds. Paper presented at Dioxin 2012, 32nd International Symposium on Halogenated Persistent Organic Pollutants, Cairns, Australia, August 26-31, 2012 (pp. 228-230).
Doctoral theses, comprehensive summaries
Kärrman, A. (2006). Analysis and human levels of persistent perfluorinated chemicals.
(Doctoral dissertation).
(Comprehensive summary)
Örebro: Örebro universitetsbibliotek.
Manuscripts
Koch, A. , Yukioka, S. , Tanaka, S. , Yeung, L. W. Y. , Kärrman, A.
& Wang, T. Characterization of an AFFF impacted freshwater environment using total fluorine, extractable organofluorine and suspect per- and polyfluoroalkyl substance screening analysis.
Schönlau, C. , Karlsson, T. , Rotander, A. , Nilsson, H. , Engwall, M. , van Bavel, B.
& Kärrman, A. Microplastics in sea-surface waters surrounding Sweden sampled by manta trawl and in-situ pump.
Koch, A. , Jonsson, M. , Yeung, L. W. Y. , Kärrman, A. , Ahrens, L. , Ekblad, A.
& Wang, T. Per- and polyfluoroalkyl contaminated freshwater impacts adjacent riparian food webs.
Koch, A. , Jonsson, M. , Yeung, L. W. Y. , Kärrman, A. , Ahrens, L. , Ekblad, A.
& Wang, T. Quantification of biodriven transfer of per- and polyfluoroalkyl substances from the aquatic to the terrestrial environment via emergent insects.
Schönlau, C. , Holmes, B. , Larsson, M. , Engwall, M.
& Kärrman, A. Screening for bioactivities in three types of microplastics deployed in Swedish aquatic environments using a battery of reporter gene assays.
Reports
Fredriksson, F. , Eriksson, U. , Kärrman, A.
& Yeung, L. (2020). A Pilot Study of the Fluorinated Ingredient of Scotchgard Products and Their Levels in WWTP Sludge and Landfill Leachate from Sweden. Örebro: Örebro universitet.
Rotander, A.
& Kärrman, A. (2019). Microplastics in Södertälje: From Lake Mälaren to the Baltic Sea. Örebro: Örebro universitet.
Kärrman, A. , Wang, T. , Kallenborn, R. , Langseter, A. M. , Grønhovd, S. M. , Ræder, E. M. , Lyche, J. L. , Yeung, L. W. Y.
& et al.
(2019). PFASs in the Nordic environment: Screening of Poly- and Perfluoroalkyl Substances (PFASs) and Extractable Organic Fluorine (EOF) in the Nordic Environment. Copenhagen: Nordisk Ministerråd (TemaNord 2019:515).
Karlsson, T. , Kärrman, A. , Rotander, A.
& Hassellöv, M. (2018). Provtagningsmetoder för mikroplast >300 μm i ytvatten: En jämförelsestudie mellan pump och trål. Göteborgs universitet & Örebro universitet.
Eriksson, U. , Haglund, P.
& Kärrman, A. (2017). Screening of PFASs in sludge and water from waste water treatment plants. Umeå: Umeå universitet.
Yeung, L. W. Y.
& Eriksson, U. (2017). Tidstrend av oidentifierade poly- och perfluorerade alkylämnen i slam från reningsverk i Sverige. Naturvårdsverket.
Kärrman, A. , Schönlau, C.
& Engwall, M. (2016). Exposure and effects of microplastics on wildlife: A review of existing data. Örebro: Örebro universitet.
Yeung, L. W. Y. , Eriksson, U.
& Kärrman, A. (2016). Pilotstudie avseende oidentifierade poly- och perfluorerade alkylämnen i slam och avloppsvatten från reningsverk i Sverige. Naturvårdsverket.
Kärrman, A. , Bjurlid, F. , Hagberg, J. , Ricklund, N. , Larsson, M. , Stubleski, J.
& Hollert, H. (2016). Study of environmental and human health impacts of firefighting agents: A technical report. Örebro, Sweden: Örebro University.
Järnberg, U. , Holmström, K. , van Bavel, B.
& Kärrman, A. (2007). Perfluoroalkylated acids and related compounds (PFAS) in the Swedish environment. Stockholm: Stockholms universitet, institutionen för tillämpad miljövetenskap (ITM).