Anna Kärrman
Tjänstetitel: Universitetslektor Organisation: Institutionen för naturvetenskap och teknik
E-post:
Telefon: 019 301401
Rum: B3315
Om Anna Kärrman
Anna Kärrman är proprefekt för Institutionen för naturvetenskap och teknik, och docent i miljökemi vid Människa-Teknik-Miljö (MTM) Forskningscentrum.
Forskning
Anna Kärrman’s huvudsakliga forskningsinriktning är att identifiera potentiellt farliga ämnen genom att använda relevanta och känsliga metoder inklusive förutsättningslös analys. Fokus är på att genom analytisk kemi identifiera organiska föroreningar samt undersöka vart de kommer ifrån, hur de rör sig i miljön och hur människor exponeras. Bland hennes forskningsprojekt finns studier av per- och polyfluoralkyl substanser, samt mikroplaster. Forskningen bedrivs främst inom profilen Environmental Forensic Laboratory (EnForce), där hon också verkar som biträdande profilansvarig. Bland hennes externa uppdrag är Svenska Kemistsamfundets redaktionsråd och Toxikologiska rådet, den senare en expertgrupp som fungerar som ett varningssystem för identifiering av kemiska ämnen som kan vara skadliga för människors hälsa eller miljön.
Forskningsprojekt
Forskningsprojekt
- Analys av Totalt Organiskt Fluor (TOF) - Avlopp
- Analys av Totalt Organiskt Fluor (TOF) - Tidstrend slam
- Baltic Sea Expedition 2014
- Biomonitorering av PFAS-ämnen i Sverige
- Exponering av föregångarämnen till PFAS
- Exponering för miljöföroreningar hos barn
- FN:s globala övervakning av PFAS i modersmjölk
- Förekomst av mikroplast i svenska sjöar
- Global Monitoring Plan on Persistent Organic Pollutants
- Har exponeringen för högfluorerade ämnen ökat för människor och miljön?
- Identifiering av okända föroreningar
- Implementering av ett nytt tillvägagångssätt för att identifiera okända potentiellt skadliga kemikalier i damm
- Kemiska risker med plast i det marina ekosystemet
- Miljöneutrala brandsläckningsmetodiker
- Mixture-Risk
- PAC-Risk
- Per- och polyfluoralkylföreningars effekter på ämnesomsättningen studerade i en embryonal fågelmodell
- PFAS-Risk
- Screening av fluororganiska ämnen (TOF) och nya PFAS-ämnen i den svenska miljön
- Screening av PFAS och fluororganiska ämnen (TOF) i Norden
- Släckvätskors miljö- och hälsopåverkan
- Ultrakortkedjiga högfluorerade ämnen i den svenska miljön - ett okänt hot mot miljön?
- Överföring av högfluorerade ämnen från vattenmiljö till landekosystem: mekanismer och ekologiska effekter
Forskargrupper
Forskargrupper
Publikationer
Publikationer
Artiklar i tidskrifter |
Doktorsavhandlingar, sammanläggningar |
Kapitel i böcker, del av antologier |
Konferensbidrag |
Manuskript |
Rapporter |
Artiklar i tidskrifter
Schönlau, C. , Larsson, M. , Lam, M. M. , Engwall, M. , Giesy, J. P. , Rochman, C.
& Kärrman, A. (2019). Aryl hydrocarbon receptor-mediated potencies in field-deployed plastics vary by type of polymer. Environmental science and pollution research international, 26 (9), 9097-9088.
Lind, P. M. , Salihovic, S. , Stubleski, J. , Kärrman, A.
& Lind, L. (2019). Association of Exposure to Persistent Organic Pollutants With Mortality Risk: An Analysis of Data From the Prospective Investigation of Vasculature in Uppsala Seniors (PIVUS) Study. JAMA network open, 2 (4).
Schönlau, C. , Larsson, M. , Dubocq, F. , Rotander, A. , Van der Zande, R. , Engwall, M.
& Kärrman, A. (2019). Effect-Directed Analysis of Ah Receptor-Mediated Potencies in Microplastics Deployed in a Remote Tropical Marine Environment. Frontiers in Environmental Science, 7.
Salihovic, S. , Fall, T. , Ganna, A. , Broeckling, C. D. , Prenni, J. E. , Hyötyläinen, T. , Kärrman, A. , Lind, P. M.
& et al.
(2019). Identification of metabolic profiles associated with human exposure to perfluoroalkyl substances. Journal of Exposure Science and Environmental Epidemiology, 29 (2), 196-205.
Stubleski, J. , Kukucka, P. , Salihovic, S. , Lind, P. M. , Lind, L.
& Kärrman, A. (2018). A method for analysis of marker persistent organic pollutants in low-volume plasma and serum samples using 96-well plate solid phase extraction. Journal of Chromatography A, 1546, 18-27.
Salihovic, S. , Stubleski, J. , Kärrman, A. , Larsson, A. , Fall, T. , Lind, L.
& Lind, P. M. (2018). Changes in markers of liver function in relation to changes in perfluoroalkyl substances: A longitudinal study. Environment International, 117, 196-203.
Lind, P. M. , Salihovic, S. , Stubleski, J. , Kärrman, A.
& Lind, L. (2018). Changes in plasma levels of perfluoroalkyl substances (PFASs) are related to increase in carotid intima-media thickness over 10 years - a longitudinal study. Environmental health, 17.
Stubleski, J. , Lind, L. , Salihovic, S. , Lind, P. M.
& Kärrman, A. (2018). Longitudinal changes in persistent organic pollutants (POPs) from 2001 to 2009 in a sample of elderly Swedish men and women. Environmental Research, 165, 193-200.
Eriksson, U. , Haglund, P.
& Kärrman, A. (2017). Contribution of precursor compounds to the release of per- and polyfluoroalkyl substances (PFASs) from waste water treatment plants (WWTPs). Journal of Environmental Sciences(China), 61, 80-90.
Blanc, M. , Kärrman, A. , Kukučka, P. , Scherbak, N.
& Keiter, S. (2017). Mixture-specific gene expression in zebrafish (Danio rerio) embryos exposed to perfluorooctane sulfonic acid (PFOS), perfluorohexanoic acid (PFHxA) and 3,3′,4,4′,5-pentachlorobiphenyl (PCB126). Science of the Total Environment, 590-591, 249-257.
Bjurlid, F. , Kärrman, A. , Ricklund, N.
& Hagberg, J. (2017). Occurrence of brominated dioxins in a study using various firefighting methods. Science of the Total Environment, 599-600, 1213-1221.
Eriksson, U. , Mueller, J. F. , Toms, L. L. , Hobson, P.
& Kärrman, A. (2017). Temporal trends of PFSAs, PFCAs and selected precursors in Australian serum from 2002 to 2013. Environmental Pollution, 220 (Pt A), 168-177.
Lind, M. , Salihovic, S. , Stubleski, J. , Kärrman, A. , van Bavel, B.
& Lind, L. (2017). The changes in plasma levels of perfluoroalkyl substances (PFASs) are related to the increase in carotid intima-media thickness over 10 years. Atherosclerosis, 263, E18-E18.
Stubleski, J. , Salihovic, S. , Lind, P. M. , Lind, L. , Dunder, L. , McCleaf, P. , Eurén, K. , Ahrens, L.
& et al.
(2017). The effect of drinking water contaminated with perfluoroalkyl substances on a 10-year longitudinal trend of plasma levels in an elderly Uppsala cohort. Environmental Research, 159, 95-102.
Stubleski, J. , Salihovic, S. , Lind, L. , Lind, P. M. , van Bavel, B.
& Kärrman, A. (2016). Changes in serum levels of perfluoroalkyl substances during a 10-year follow-up period in a large population-based cohort. Environment International, 95, 86-92.
Eriksson, U. , Roos, A. , Lind, Y. , Hope, K. , Ekblad, A.
& Kärrman, A. (2016). Comparison of PFASs contamination in the freshwater and terrestrial environments by analysis of eggs from osprey (Pandion haliaetus), tawny owl (Strix aluco), and common kestrel (Falco tinnunculus). Environmental Research, 149, 40-47.
Mattsson, A. , Kärrman, A. , Pinto, R.
& Brunström, B. (2015). Metabolic Profiling of Chicken Embryos Exposed to Perfluorooctanoic Acid ( PFOA) and Agonists to Peroxisome Proliferator-Activated Receptors. PLoS ONE, 10 (12).
Rotander, A. , Kärrman, A. , Toms, L. L. , Kay, M. , Mueller, J. F.
& Gómez Ramos, M. J. (2015). Novel fluorinated surfactants tentatively identified in firefighters using liquid chromatography quadrupole time-of-flight tandem mass spectrometry and a case-control approach. Environmental Science and Technology, 49 (4), 2434-2442.
Salihovic, S. , Kärrman, A. , Lind, L. , Lind, P. M. , Lindström, G.
& van Bavel, B. (2015). Perfluoroalkyl substances (PFAS) including structural PFOS isomers in plasma from elderly men and women from Sweden: Results from the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS). Environment International, 82 (Sept 2015), 21-27.
Eriksson, U.
& Kärrman, A. (2015). World-Wide Indoor Exposure to Polyfluoroalkyl Phosphate Esters (PAPs) and other PFASs in Household Dust. Environmental Science and Technology, 49 (24), 14503-14511.
Hardell, E. , Kärrman, A. , van Bavel, B. , Bao, J. , Carlberg, M.
& Hardell, L. (2014). Case-control study on perfluorinated alkyl acids (PFAAs) and the risk of prostate cancer. Environment International, 63, 35-39.
Kärrman, A. , Ericson Jogsten, I. , Davies, J. , van Bavel, B. , Holsen, A. H.
& Laugesen, J. (2014). Per- and polyfluoroalkyl substances in effluents from hazardous waste treatment facilities. Organohalogen Compounds, 76.
Bao, J. , Kärrman, A. , van Bavel, B.
& Jin, Y. (2014). Perfluoroalkyl substances in the blood samples from a male population of Sweden. Chinese Science Bulletin, 59 (4), 388-395.
Salihovic, S. , Kärrman, A. , Lindström, G. , Lind, P. M. , Lind, L.
& van Bavel, B. (2013). A rapid method for the determination of perfluoroalkyl substances including structural isomers of perfluorooctane sulfonic acid in human serum using 96-well plates and column-switching ultra-high performance liquid chromatography tandem mass spectrometry. Journal of Chromatography A, 1305, 164-170.
Nilsson, H. , Kärrman, A. , Rotander, A. , van Bavel, B. , Lindström, G.
& Westberg, H. (2013). Biotransformation of fluorotelomer compound to perfluorocarboxylates in humans. Environment International, 51, 8-12.
Persson, S. , Rotander, A. , Kärrman, A. , van Bavel, B.
& Magnusson, U. (2013). Perfluoroalkyl acids in subarctic wild male mink (Neovison vison) in relation to age, season and geographical area. Environment International, 59, 425-430.
Eriksson, U. , Kärrman, A. , Rotander, A. , Mikkelsen, B.
& Dam, M. (2013). Perfluoroalkyl substances (PFASs) in food and water from Faroe Islands. Environmental science and pollution research international, 20 (11), 7940-7948.
Nilsson, H. , Kärrman, A. , Rotander, A. , van Bavel, B. , Lindström, G.
& Westberg, H. (2013). Professional ski waxers' exposure to PFAS and aerosol concentrations in gas phase and different particle size fractions. Environmental science. Processes & impacts, 15 (4), 814-822.
Kärrman, A.
& Lindström, G. (2013). Trends, analytical methods and precision in the determination of perfluoroalkyl acids in human milk. TrAC. Trends in analytical chemistry, 46, 118-128.
Domingo, J. L. , Ericson-Jogsten, I. , Perello, G. , Nadal, M. , van Bavel, B.
& Kärrman, A. (2012). Human exposure to perfluorinated compounds in Catalonia, Spain: contribution of drinking water and fish and shellfish. Journal of Agricultural and Food Chemistry, 60 (17), 4408-4415.
Rotander, A. , Kärrman, A. , van Bavel, B. , Polder, A. , Riget, F. , Atli Auounsson, G. , Vikingsson, G. , Wing Gabrielsen, G.
& et al.
(2012). Increasing levels of long-chain perfluorocarboxylic acids (PFCAs) in Arctic and North Atlantic marine mammals, 1984-2009. Chemosphere, 86 (3), 278-285.
Strömqvist, M. , Olsson, J. A. , Kärrman, A.
& Brunström, B. (2012). Transcription of genes involved in fat metabolism in chicken embryos exposed to the peroxisome proliferator-activated receptor alpha (PPAR alpha) agonist GW7647 or to perfluorooctane sulfonate (PFOS) or perfluorooctanoic acid (PFOA). Comparative Biochemistry and Physiology - Part C: Toxicology & Pharmacology, 156 (1), 29-36.
Kärrman, A. , Elgh-Dalgren, K. , Lafossas, C.
& Moskeland, T. (2011). Environmental levels and distribution of structural isomers of perfluoroalkyl acids after aqueous fire-fighting foam (AFFF) contamination. Environmental Chemistry, 8 (4), 372-380.
Berger, U. , Kaiser, M. A. , Kärrman, A. , Barber, J. L.
& van Leeuwen, S. P. J. (2011). Recent developments in trace analysis of poly- and perfluoroalkyl substances. Analytical and Bioanalytical Chemistry, 400 (6), 1625-1635.
Nilsson, H. , Kärrman, A. , Westberg, H. , Rotander, A. , van Bavel, B.
& Lindström, G. (2010). A time trend study of significantly elevated perfluorocarboxylate levels in humans after using fluorinated ski wax. Environmental Science and Technology, 44 (6), 2150-2155.
Kärrman, A. , Domingo, J. L. , Llebaria, X. , Nadal, M. , Bigas, E. , van Bavel, B.
& Lindström, G. (2010). Biomonitoring perfluorinated compounds in Catalonia, Spain: concentrations and trends in human liver and milk samples. Environmental science and pollution research international, 17 (3), 750-758.
Nilsson, H. , Kärrman, A. , Rotander, A. , van Bavel, B. , Lindström, G.
& Westberg, H. (2010). Inhalation exposure to fluorotelomer alcohols yield perfluorocarboxylates in human blood?. Environmental Science and Technology, 44 (19), 7717-7722.
Minata, M. , Harada, K. H. , Kärrman, A. , Hitomi, T. , Hirosawa, M. , Murata, M. , Gonzalez, F. J.
& Koizumi, A. (2010). Role of Peroxisome Proliferator-activated Receptor-alpha in Hepatobiliary Injury Induced by Ammonium Perfluorooctanoate in Mouse Liver. Industrial Health, 48 (1), 96-107.
Lindström, G. , Kärrman, A.
& van Bavel, B. (2009). Accuracy and precision in the determination of perfluorinated chemicals in human blood verified by interlaboratory comparisons. Journal of Chromatography A, 1216 (3), 394-400.
Ericson Jogsten, I. , Perelló, G. , Llebaria, X. , Bigas, E. , Martí-Cid, R. , Kärrman, A.
& Domingo, J. L. (2009). Exposure to perfluorinated compounds in Catalonia, Spain, through consumption of various raw and cooked foodstuffs, including packaged food. Food and Chemical Toxicology, 47 (7), 1577-1583.
Mahmoud, M. A. M. , Kärrman, A. , Oono, S. , Harada, K. H.
& Koizumi, A. (2009). Polyfluorinated telomers in precipitation and surface water in an urban area of Japan. Chemosphere, 74 (3), 467-472.
Kärrman, A. , Harada, K. H. , Inoue, K. , Takasuga, T. , Ohi, E.
& Koizumi, A. (2009). Relationship between dietary exposure and serum perfluorochemical (PFC) levels-A case study. Environment International, 35 (4), 712-717.
Kärrman, A. , Ericson Jogsten, I. , van Bavel, B. , Darnerud, P. O. , Aune, M. , Glynn, A. , Lignell, S.
& Lindström, G. (2007). Exposure of perfluorinated chemicals through lactation: levels of matched human milk and serum and a temporal trend, 1996-2004, in Sweden. Environmental Health Perspectives, 115 (2), 226-230.
Kärrman, A. , Langlois, I. , van Bavel, B. , Lindström, G.
& Oehme, M. (2007). Identification and pattern of perfluorooctane sulfonate (PFOS) isomers in human serum and plasma. Environment International, 33 (6), 782-788.
Kärrman, A. , Mueller, J. F. , van Bavel, B. , Harden, F. , Toms, L. L.
& Lindström, G. (2006). Levels of 12 perfluorinated chemicals in pooled Australian serum, collected 2002-2003, in relation to age, gender, and region. Environmental Science and Technology, 40 (12), 3742-3748.
Kärrman, A. , van Bavel, B. , Järnberg, U. , Hardell, L.
& Lindström, G. (2006). Perfluorinated chemicals in relation to other persistent organic pollutants in human blood. Chemosphere, 64 (9), 1582-1591.
van Leeuwen, S. P. J. , Kärrman, A. , van Bavel, B. , de Boer, J.
& Lindström, G. (2006). Struggle for quality in determination of perfluorinated contaminants in environmental and human samples. Environmental Science and Technology, 40 (24), 7854-7860.
Kärrman, A. , van Bavel, B. , Järnberg, U. , Hardell, L.
& Lindström, G. (2005). Development of a solid-phase extraction-HPLC/Single quadrupole MS method for quantification of perfluorochemicals in whole blood. Analytical Chemistry, 77 (3), 864-870.
Martin, J. , Kannan, K. , Berger, U. , de Voogt, P. , Field, J. , Franklin, J. , Giesy, J. , Harner, T.
& et al.
(2004). Analytical challenges hamper perfluoroalkyl research. Environmental Science and Technology, 38 (13), 248A-255A.
Doktorsavhandlingar, sammanläggningar
Kärrman, A. (2006). Analysis and human levels of persistent perfluorinated chemicals.
(Doctoral dissertation).
(Sammanläggning)
Örebro: Örebro universitetsbibliotek.
Kapitel i böcker, del av antologier
Kärrman, A. , Parera, J. , Abalos, M. , Van Bavel, B.
& Abad, E. (2012). Assessing and controlling sample contamination: analytical techniques for scientists.
I:
Janusz Pawliszyn, Comprehensive sampling and sample preparation (ss. 51-64).
Oxford UK: Elsevier.
Konferensbidrag
Li, Y. , Hagberg, J. , Kärrman, A. , Bao, J. , Zhang, Q. , Jiang, G.
& van Bavel, B. (2012). Occurence of perfluorinated compounds in marine fish, Antarctica.
I:
Organohalogen Compounds. Konferensbidrag vid Dioxin 2012, 32nd International Symposium on Halogenated Persistent Organic Pollutants, Cairns, Australia, August 26-31, 2012 (ss. 228-230).
Manuskript
Schönlau, C. , Karlsson, T. , Rotander, A. , Nilsson, H. , Engwall, M. , van Bavel, B.
& Kärrman, A. Microplastics in sea-surface waters surrounding Sweden sampled by manta trawl and in-situ pump.
Schönlau, C. , Holmes, B. , Larsson, M. , Engwall, M.
& Kärrman, A. Screening for bioactivities in three types of microplastics deployed in Swedish aquatic environments using a battery of reporter gene assays.
Rapporter
Yeung, L. W. Y.
& Eriksson, U. (2017). Tidstrend av oidentifierade poly- och perfluorerade alkylämnen i slam från reningsverk i Sverige. Naturvårdsverket.
Kärrman, A. , Schönlau, C.
& Engwall, M. (2016). Exposure and effects of microplastics on wildlife: A review of existing data. Örebro: Örebro universitet.
Yeung, L. W. Y. , Eriksson, U.
& Kärrman, A. (2016). Pilotstudie avseende oidentifierade poly- och perfluorerade alkylämnen i slam och avloppsvatten från reningsverk i Sverige. Naturvårdsverket.
Kärrman, A. , Bjurlid, F. , Hagberg, J. , Ricklund, N. , Larsson, M. , Stubleski, J.
& Hollert, H. (2016). Study of environmental and human health impacts of firefighting agents: A technical report. Örebro, Sweden: Örebro University.