Ida Schoultz
Title: Senior Lecturer School/office: School of Medical Sciences
Email:
Phone: +46 19 303209
Room: C1104
Research Subject
Research environments
About Ida Schoultz
Ida Schoultz defended her thesis entitled "Bacterial-epihelial interactions in Crohn's disease" in 2009 at Linköping University, after completing a post-doctoral period at the University of Calgary (2010-2012), Ida joined Örebro University to continue her research. Since 2019 Ida is an Associate Professor at the Department of Medical Sciences where she leads the research group "The Ageing Gut - in health and inflammation". Ida's project aims to map the mechanisms behind age-associated gastrointestinal problems but also understand the reasons behind why inflammatory bowel disease (IBD) is now increasing among older adults. By understanding the mechanisms behind gastrointestinal disorders and IBD in the elderly, important puzzle pieces are added to the understanding of how the gastrointestinal tract ages in a healthy state and how gut health can be promoted among older adults. Ida has an expertise in experimental methods for studying the gastrointestinal barrier, particularly the Ussing chamber technology, which makes it possible to study how different substances but also bacteria pass over the intestinal mucosa and affect the barrier function of the intestine. In 2019, Ida is also particpiating in the Social Impact Lab to design a model with the aim to bring knowledge regarding gut health and how it can be promoted among older adults out to society. Ida is frequently invited as a lectures for patient organizations as well as for regional and national meetings for healthcare professionals and dieticians. At the Department of Medical Sciences, Ida is the head of one of the departments units and are engaged in educational issues at the Medical program.
Below you find a short presentation on orienteering as a model of healthy ageing,
Research Projects
Research Projects
Research Teams
Research Teams
Publications
Publications
Articles in journals |
Articles, reviews/surveys |
Manuscripts |
Articles in journals
Fart, F. , Rajan, S. K. , Wall, R. , Rangel, I. , Ganda Mall, J. P. , Tingö, L. , Brummer, R. J. , Repsilber, D.
& et al.
(2020). Differences in Gut Microbiome Composition between Senior Orienteering Athletes and Community-Dwelling Older Adults. Nutrients, 12 (9).
Ganda Mall, J. P. , Fart, F. , Sabet, J. A. , Lindqvist, C. M. , Nestestog, R. , Hegge, F. T. , Keita, Å. V. , Brummer, R. J.
& et al.
(2020). Effects of Dietary Fibres on Acute Indomethacin-Induced Intestinal Hyperpermeability in the Elderly: A Randomised Placebo Controlled Parallel Clinical Trial. Nutrients, 12 (7).
Halfvarson, J. , Lundström, M. L. , Lampinen, M. , Schoultz, I. , Bodin, L.
& Carlson, M. (2020). Genetic and shared environmental risk factors do not lead to eosinophil activation in healthy twins of IBD patients. Scandinavian Journal of Gastroenterology.
Fart, F. , Salihovic, S. , McGlinchey, A. J. , Oresic, M. , Halfvarson, J. , Hyötyläinen, T.
& Schoultz, I. (2020). Per- and polyfluoroalkyl substances (PFAS) are significantly increased in patients with late-onset of ulcerative colitis. Journal of Crohn's & Colitis, 14 (Suppl. 1), S138-S139.
Salihovic, S. , Dickens, A. M. , Schoultz, I. , Fart, F. , Sinisalu, L. , Lindeman, T. , Halfvarson, J. , Oresic, M.
& et al.
(2020). Simultaneous determination of perfluoroalkyl substances and bile acids in human serum using ultra-high-performance liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry, 412 (10), 2251-2259.
Shrestha, S. , Olén, O. , Eriksson, C. , Everhov, Å. H. , Myrelid, P. , Visuri, I. , Ludvigsson, J. F. , Schoultz, I.
& et al.
(2020). The use of ICD codes to identify IBD subtypes and phenotypes of the Montreal classification in the Swedish National Patient Register. Scandinavian Journal of Gastroenterology, 55 (4), 430-435.
Rajan, S. K. , Lindqvist, C. M. , Brummer, R. J. , Schoultz, I.
& Repsilber, D. (2019). Phylogenetic microbiota profiling in fecal samples depends on combination of sequencing depth and choice of NGS analysis method. PLoS ONE, 14 (9).
Ganda Mall, J. , Östlund-Lagerström, L. , Lindqvist, C. M. , Algilani, S. , Rasoal, D. , Repsilber, D. , Brummer, R. J. , V. Keita, Å.
& et al.
(2018). Are self-reported gastrointestinal symptoms among older adults associated with increased intestinal permeability and psychological distress?. BMC Geriatrics, 18 (1).
Ganda Mall, J. P. , Löfvendahl, L. , Lindqvist, C. M. , Brummer, R. J. , Keita, Å. V.
& Schoultz, I. (2018). Differential effects of dietary fibres on colonic barrier function in elderly individuals with gastrointestinal symptoms. Scientific Reports, 8 (1).
Keita, Å. V. , Lindqvist, C. M. , Öst, Å. , Magana, C. D. L. , Schoultz, I.
& Halfvarson, J. (2018). Gut barrier dysfunction: a primary defect in twins with Crohn's disease predominantly caused by genetic predisposition. Journal of Crohn's & Colitis, 12 (10), 1200-1209.
Keita, A. V. , Lindqvist, C. M. , Ost, A. , Magana, C. D. L. , Schoultz, I.
& Halfvarson, J. (2018). Gut barrier dysfunction: a primary defect in twins with Crohn's disease predominantly caused by genetic predisposition. Journal of Crohn's & Colitis, 12 (Suppl. 1), S1-S1.
Yakymenko, O. , Schoultz, I. , Gullberg, E. , Ström, M. , Almer, S. , Wallon, C. , Wang, A. , Keita, Å. V.
& et al.
(2018). Infliximab restores colonic barrier to adherent-invasive E. coli in Crohn's disease via effects on epithelial lipid rafts. Scandinavian Journal of Gastroenterology, 53 (6), 677-684.
Ganda Mall, J. , Casado-Bedmar, M. , Winberg, M. E. , Brummer, R. J. , Schoultz, I.
& Keita, Å. V. (2017). A β-Glucan-Based Dietary Fiber Reduces Mast Cell-Induced Hyperpermeability in Ileum From Patients With Crohn's Disease and Control Subjects. Inflammatory Bowel Diseases, 24 (1), 166-178.
Algilani, S. , Östlund-Lagerström, L. , Schoultz, I. , Brummer, R. J.
& Kihlgren, A. (2016). Increasing the qualitative understanding of optimal functionality in older adults: a focus group based study. BMC Geriatrics, 16 (1).
Östlund-Lagerström, L. , Kihlgren, A. , Repsilber, D. , Björkstén, B. , Brummer, R. J.
& Schoultz, I. (2016). Probiotic administration among free-living older adults: a double blinded, randomized, placebo-controlled clinical trial. Nutrition Journal, 15.
Östlund-Lagerström, L. , Blomberg, K. , Algilani, S. , Schoultz, M. , Kihlgren, A. , Brummer, R. J.
& Schoultz, I. (2015). Senior orienteering athletes as a model of healthy aging: a mixed-method approach. BMC Geriatrics, 15.
Wang, A. , Keita, Å. V. , Phan, V. , McKay, C. M. , Schoultz, I. , Lee, J. , Murphy, M. P. , Fernando, M.
& et al.
(2014). Targeting mitochondria-derived reactive oxygen species to reduce epithelial barrier dysfunction and colitis. American Journal of Pathology, 184 (9), 2516-2527.
Schoultz, I. , McKay, C. M. , Graepel, R. , Phan, V. C. , Wang, A. , Söderholm, J.
& McKay, D. M. (2012). Indomethacin-induced translocation of bacteria across enteric epithelia is reactive oxygen species-dependent and reduced by vitamin C. American Journal of Physiology - Gastrointestinal and Liver Physiology, 303 (5), G536-G545.
Zurek, B. , Schoultz, I. , Neerincx, A. , Napolitano, L. M. , Birkner, K. , Bennek, E. , Sellge, G. , Lerm, M.
& et al.
(2012). TRIM27 negatively regulates NOD2 by ubiquitination and proteasomal degradation. PLoS ONE, 7 (7).
Schoultz, I. , Verma, D. , Halfvarson, J. , Törkvist, L. , Fredrikson, M. , Sjöqvist, U. , Lördal, M. , Tysk, C.
& et al.
(2009). Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men. American Journal of Gastroenterology, 104 (5), 1180-1188.
Schoultz, I. , Verma, D. , Törkvist, L. , Halfvarson, J. , Lerm, M. , Söderkvist, P.
& Söderholm, J. D. (2008). M2080 Compound Polymorphisms in CARD8 and CIAS1 Predispose to Crohn's Disease in a Swedish Cohort. Gastroenterology, 134 (4), A464-A465.
Ragnarsson, E. G. E. , Schoultz, I. , Gullberg, E. , Carlsson, A. H. , Tafazoli, F. , Lerm, M. , Magnusson, K. , Söderholm, J. D.
& et al.
(2008). Yersinia pseudotuberculosis induces transcytosis of nanoparticles across human intestinal villus epithelium via invasin-dependent macropinocytosis. Laboratory Investigation, 88 (11), 1215-26.
Seibert, V. , Prohl, C. , Schoultz, I. , Rhee, E. , Lopez, R. , Abderazzaq, K. , Zhou, C.
& Wolf, D. A. (2002). Combinatorial diversity of fission yeast SCF ubiquitin ligases by homo- and heterooligomeric assemblies of the F-box proteins Pop1p and Pop2p. BMC biochemistry, 3, 1-15.
Articles, reviews/surveys
Schoultz, I.
& Keita, Å. V. (2020). The Intestinal Barrier and Current Techniques for the Assessment of Gut Permeability. Cells, 9 (8).
Schoultz, I.
& Keita, Å. V. (2019). Cellular and Molecular Therapeutic Targets in Inflammatory Bowel Disease-Focusing on Intestinal Barrier Function. Cells, 8 (2).
Algilani, S. , Östlund-Lagerström, L. , Kihlgren, A. , Blomberg, K. , Brummer, R. J.
& Schoultz, I. (2014). Exploring the concept of optimal functionality in old age. Journal of Multidisciplinary Healthcare, 7, 69-79.
Schoultz, I. , Söderholm, J. D.
& McKay, D. M. (2011). Is metabolic stress a common denominator in inflammatory bowel disease?. Inflammatory Bowel Diseases, 17 (9), 2008-18.
Manuscripts
Ganda Mall, J. , Löfvendahl, L. , Brummer, R. J. , Keita, Å. V.
& Schoultz, I. Differential effects of dietary fibres on colonic barrier function in elderly individuals with gastrointestinal symptoms.
Ganda Mall, J. , Fart, F. , Sabet, J. , Lindqvist, C. , Keita, Å. V. , Brummer, R. J.
& Schoultz, I. Effects of dietary fibres on indomethacin-induced intestinal permeability in elderly : A randomised placebo controlled parallel clinical trial.
Östlund-Lagerström, L. , Ganda Mall, J. , Algilani, S. , Rasoal, D. , Brummer, R. J.
& Schoultz, I. Low levels of inflammation and oxidative stress in senior orienteering athletes.
Algilani, S. , Östlund-Lagerström, L. , Kihlgren, A. , Schoultz, I.
& Schröder, A. Mental health as a prerequisite for functioning as optimally as possible in old age : a phenomenological approach.
Östlund-Lagerström, L. , Kihlgren, A. , Repsilber, D. , Björkstén, B. , Brummer, R. J.
& Schoultz, I. Probiotic administration among free-living older adults : a double blinded, randomised, placebo-controlled clinical trial.