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Ida Schoultz

Position: Senior Lecturer School/office: School of Medical Sciences

Email: aWRhLnNjaG91bHR6O29ydS5zZQ==

Phone: +46 19 303209

Room: X5506

Research subject

Medicine

About Ida Schoultz

Ida Schoultz is an Associate Professor (Docent) and Senior Lecturer in Medical Sciences with a research focus on inflammatory bowel disease (IBD). Her work explores the interplay between the intestinal barrier, the immune system, and the microbiota, aiming to increase understanding of the mechanisms underlying disease development. She has particular expertise in experimental models for studying intestinal barrier function, especially the Ussing chamber technique, as well as in molecular biology methods and advanced cell culture models.

She is Deputy Programme Director of the Medical Programme with a focus on biomedicine and teaches in the early semesters, primarily in gastrointestinal physiology.

In addition to research and teaching, Ida also gives lectures aimed at a broader audience on IBD, gut health, and the immune system, and has appeared on Swedish programmes such as Malou after tio and UR Samtiden.

Active projects

Completed projects

Research groups

Publications

Articles in journals | Articles, reviews/surveys | Conference papers |

Articles in journals

Shrestha, S. , Brand, J. S. , Osooli, M. , Eriksson, C. , Schoultz, I. , Askling, J. , Jess, T. , Montgomery, S. & et al. (2024). Spondyloarthritis in first-degree relatives and spouses of patients with inflammatory bowel disease: A nationwide population-based cohort study from Sweden. Journal of Crohn's & Colitis, 18 (9), 1371-1380. [BibTeX]
Shrestha, S. , Brand, J. S. , Järås, J. , Schoultz, I. , Montgomery, S. , Askling, J. , Ludvigsson, J. F. , Olen, O. & et al. (2022). Association between inflammatory bowel disease and spondyloarthritis: findings from a nationwide study in Sweden. Journal of Crohn's & Colitis, 16 (1), 1540-1550. [BibTeX]
Fart, F. , Tingö, L. , Engelheart, S. , Lindqvist, C. M. , Brummer, R. J. , Kihlgren, A. & Schoultz, I. (2022). Gut Health and Its Association with Wellbeing and Nutrient Intake in Community-Dwelling Older Adults. Gastroenterology Insights, 13 (4), 349-364. [BibTeX]
Fart, F. , Salihovic, S. , McGlinchey, A. J. , Gareau, M. G. , Oresic, M. , Halfvarson, J. , Hyötyläinen, T. & Schoultz, I. (2021). Perfluoroalkyl substances are increased in patients with late-onset ulcerative colitis and induce intestinal barrier defects ex vivo in murine intestinal tissue. Scandinavian Journal of Gastroenterology, 56 (11), 1286-1295. [BibTeX]
Fart, F. , Rajan, S. K. , Wall, R. , Rangel, I. , Ganda Mall, J. P. , Tingö, L. , Brummer, R. J. , Repsilber, D. & et al. (2020). Differences in Gut Microbiome Composition between Senior Orienteering Athletes and Community-Dwelling Older Adults. Nutrients, 12 (9). [BibTeX]
Ganda Mall, J. P. , Fart, F. , Sabet, J. A. , Lindqvist, C. M. , Nestestog, R. , Hegge, F. T. , Keita, Å. V. , Brummer, R. J. & et al. (2020). Effects of Dietary Fibres on Acute Indomethacin-Induced Intestinal Hyperpermeability in the Elderly: A Randomised Placebo Controlled Parallel Clinical Trial. Nutrients, 12 (7). [BibTeX]
Halfvarson, J. , Lundström, M. L. , Lampinen, M. , Schoultz, I. , Bodin, L. & Carlson, M. (2020). Genetic and shared environmental risk factors do not lead to eosinophil activation in healthy twins of IBD patients. Scandinavian Journal of Gastroenterology, 55 (10), 1163-1170. [BibTeX]
Salihovic, S. , Dickens, A. M. , Schoultz, I. , Fart, F. , Sinisalu, L. , Lindeman, T. , Halfvarson, J. , Oresic, M. & et al. (2020). Simultaneous determination of perfluoroalkyl substances and bile acids in human serum using ultra-high-performance liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry, 412 (10), 2251-2259. [BibTeX]
Shrestha, S. , Olén, O. , Eriksson, C. , Everhov, Å. H. , Myrelid, P. , Visuri, I. , Ludvigsson, J. F. , Schoultz, I. & et al. (2020). The use of ICD codes to identify IBD subtypes and phenotypes of the Montreal classification in the Swedish National Patient Register. Scandinavian Journal of Gastroenterology, 55 (4), 430-435. [BibTeX]
Rajan, S. K. , Lindqvist, C. M. , Brummer, R. J. , Schoultz, I. & Repsilber, D. (2019). Phylogenetic microbiota profiling in fecal samples depends on combination of sequencing depth and choice of NGS analysis method. PLOS ONE, 14 (9). [BibTeX]
Ganda Mall, J. , Östlund-Lagerström, L. , Lindqvist, C. M. , Algilani, S. , Rasoal, D. , Repsilber, D. , Brummer, R. J. , V. Keita, Å. & et al. (2018). Are self-reported gastrointestinal symptoms among older adults associated with increased intestinal permeability and psychological distress?. BMC Geriatrics, 18 (1). [BibTeX]
Ganda Mall, J. P. , Löfvendahl, L. , Lindqvist, C. M. , Brummer, R. J. , Keita, Å. V. & Schoultz, I. (2018). Differential effects of dietary fibres on colonic barrier function in elderly individuals with gastrointestinal symptoms. Scientific Reports, 8 (1). [BibTeX]
Keita, Å. V. , Lindqvist, C. M. , Öst, Å. , Magana, C. D. L. , Schoultz, I. & Halfvarson, J. (2018). Gut barrier dysfunction: a primary defect in twins with Crohn's disease predominantly caused by genetic predisposition. Journal of Crohn's & Colitis, 12 (10), 1200-1209. [BibTeX]
Yakymenko, O. , Schoultz, I. , Gullberg, E. , Ström, M. , Almer, S. , Wallon, C. , Wang, A. , Keita, Å. V. & et al. (2018). Infliximab restores colonic barrier to adherent-invasive E. coli in Crohn's disease via effects on epithelial lipid rafts. Scandinavian Journal of Gastroenterology, 53 (6), 677-684. [BibTeX]
Ganda Mall, J. , Casado-Bedmar, M. , Winberg, M. E. , Brummer, R. J. , Schoultz, I. & Keita, Å. V. (2017). A β-Glucan-Based Dietary Fiber Reduces Mast Cell-Induced Hyperpermeability in Ileum From Patients With Crohn's Disease and Control Subjects. Inflammatory Bowel Diseases, 24 (1), 166-178. [BibTeX]
Algilani, S. , Östlund-Lagerström, L. , Schoultz, I. , Brummer, R. J. & Kihlgren, A. (2016). Increasing the qualitative understanding of optimal functionality in older adults: a focus group based study. BMC Geriatrics, 16 (1). [BibTeX]
Östlund-Lagerström, L. , Kihlgren, A. , Repsilber, D. , Björkstén, B. , Brummer, R. J. & Schoultz, I. (2016). Probiotic administration among free-living older adults: a double blinded, randomized, placebo-controlled clinical trial. Nutrition Journal, 15. [BibTeX]
Östlund-Lagerström, L. , Blomberg, K. , Algilani, S. , Schoultz, M. , Kihlgren, A. , Brummer, R. J. & Schoultz, I. (2015). Senior orienteering athletes as a model of healthy aging: a mixed-method approach. BMC Geriatrics, 15. [BibTeX]
Wang, A. , Keita, Å. V. , Phan, V. , McKay, C. M. , Schoultz, I. , Lee, J. , Murphy, M. P. , Fernando, M. & et al. (2014). Targeting mitochondria-derived reactive oxygen species to reduce epithelial barrier dysfunction and colitis. American Journal of Pathology, 184 (9), 2516-2527. [BibTeX]
Schoultz, I. , McKay, C. M. , Graepel, R. , Phan, V. C. , Wang, A. , Söderholm, J. & McKay, D. M. (2012). Indomethacin-induced translocation of bacteria across enteric epithelia is reactive oxygen species-dependent and reduced by vitamin C. American Journal of Physiology - Gastrointestinal and Liver Physiology, 303 (5), G536-G545. [BibTeX]
Zurek, B. , Schoultz, I. , Neerincx, A. , Napolitano, L. M. , Birkner, K. , Bennek, E. , Sellge, G. , Lerm, M. & et al. (2012). TRIM27 negatively regulates NOD2 by ubiquitination and proteasomal degradation. PLOS ONE, 7 (7). [BibTeX]
Schoultz, I. , Verma, D. , Halfvarson, J. , Törkvist, L. , Fredrikson, M. , Sjöqvist, U. , Lördal, M. , Tysk, C. & et al. (2009). Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men. American Journal of Gastroenterology, 104 (5), 1180-1188. [BibTeX]
Ragnarsson, E. G. E. , Schoultz, I. , Gullberg, E. , Carlsson, A. H. , Tafazoli, F. , Lerm, M. , Magnusson, K. , Söderholm, J. D. & et al. (2008). Yersinia pseudotuberculosis induces transcytosis of nanoparticles across human intestinal villus epithelium via invasin-dependent macropinocytosis. Laboratory Investigation, 88 (11), 1215-26. [BibTeX]
Seibert, V. , Prohl, C. , Schoultz, I. , Rhee, E. , Lopez, R. , Abderazzaq, K. , Zhou, C. & Wolf, D. A. (2002). Combinatorial diversity of fission yeast SCF ubiquitin ligases by homo- and heterooligomeric assemblies of the F-box proteins Pop1p and Pop2p. BMC Biochemistry, 3, 1-15. [BibTeX]

Articles, reviews/surveys

Schoultz, I. , Claesson, M. J. , Dominguez-Bello, M. G. , Fåk Hållenius, F. , Konturek, P. , Korpela, K. , Laursen, M. F. , Penders, J. & et al. (2025). Gut microbiota development across the lifespan: Disease links and health-promoting interventions. Journal of Internal Medicine, 297 (6), 560-583. [BibTeX]
Schoultz, I. & Keita, Å. V. (2020). The Intestinal Barrier and Current Techniques for the Assessment of Gut Permeability. Cells, 9 (8). [BibTeX]
Schoultz, I. & Keita, Å. V. (2019). Cellular and Molecular Therapeutic Targets in Inflammatory Bowel Disease-Focusing on Intestinal Barrier Function. Cells, 8 (2). [BibTeX]
Algilani, S. , Östlund-Lagerström, L. , Kihlgren, A. , Blomberg, K. , Brummer, R. J. & Schoultz, I. (2014). Exploring the concept of optimal functionality in old age. Journal of Multidisciplinary Healthcare, 7, 69-79. [BibTeX]
Schoultz, I. , Söderholm, J. D. & McKay, D. M. (2011). Is metabolic stress a common denominator in inflammatory bowel disease?. Inflammatory Bowel Diseases, 17 (9), 2008-18. [BibTeX]

Conference papers

Beaudeau, J. , Katinios, G. , Biskou, O. , Lindqvist, C. M. , Walter, S. A. , Bednarska, O. , Söderholm, J. D. , Salomon, B. & et al. (2025). Differential expression of enteric glial cell markers in inflamed and non-inflamed tissue of patients with Ulcerative Colitis during clinically active disease and remission. In: Journal of Crohn's & Colitis. Paper presented at 20th Congress of ECCO, Berlin, Germany, February 19-22, 2025. (pp. I567-I567). Oxford University Press. [BibTeX]
Fart, F. , Salihovic, S. , McGlinchey, A. J. , Oresic, M. , Halfvarson, J. , Hyötyläinen, T. & Schoultz, I. (2020). Per- and polyfluoroalkyl substances (PFAS) are significantly increased in patients with late-onset of ulcerative colitis. In: Journal of Crohn's & Colitis. Oxford University Press. [BibTeX]
Keita, A. V. , Lindqvist, C. M. , Ost, A. , Magana, C. D. L. , Schoultz, I. & Halfvarson, J. (2018). Gut barrier dysfunction: a primary defect in twins with Crohn's disease predominantly caused by genetic predisposition. In: Journal of Crohn's & Colitis. Oxford University Press. [BibTeX]
Schoultz, I. , Verma, D. , Törkvist, L. , Halfvarson, J. , Lerm, M. , Söderkvist, P. & Söderholm, J. D. (2008). M2080 Compound Polymorphisms in CARD8 and CIAS1 Predispose to Crohn's Disease in a Swedish Cohort. In: Gastroenterology. Saunders Elsevier. [BibTeX]