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Magnus Engwall

Title: Professor School/office: School of Science and Technology

Email:

Phone: +46 19 303606

Room: B3305

Magnus Engwall

Research subject

Research environments

About Magnus Engwall

My research is directed towards studying receptor-mediated effects of organic environmental pollutants on living organisms. I lead several research projects using mechanism-specific bioassays for characterisation of complex mixtures of receptor-acting toxicants. These include toxicological characterisation and risk assessment of contaminated soil and sediment, marine plastic, and other complex mixtures. I am also research director of Man-Technology-Environment research center.

Publications

Articles in journals |  Articles, reviews/surveys |  Manuscripts |  Reports | 

Articles in journals

Schönlau, C. , Karlsson, T. M. , Rotander, A. , Nilsson, H. , Engwall, M. , van Bavel, B. & Kärrman, A. (2020). Microplastics in sea-surface waters surrounding Sweden sampled by manta trawl and in-situ pump. Marine Pollution Bulletin, 153.
Chavan, S. , Scherbak, N. , Engwall, M. & Repsilber, D. (2020). Predicting Chemical-Induced Liver Toxicity Using High-Content Imaging Phenotypes and Chemical Descriptors: A Random Forest Approach. Chemical Research in Toxicology, 33 (9), 2261-2275.
Schönlau, C. , Larsson, M. , Lam, M. M. , Engwall, M. , Giesy, J. P. , Rochman, C. & Kärrman, A. (2019). Aryl hydrocarbon receptor-mediated potencies in field-deployed plastics vary by type of polymer. Environmental Science and Pollution Research, 26 (9), 9097-9088.
Geng, D. , Musse, A. A. , Wigh, V. , Carlsson, C. , Engwall, M. , Oresic, M. , Scherbak, N. & Hyötyläinen, T. (2019). Effect of perfluorooctanesulfonic acid (PFOS) on the liver lipid metabolism of the developing chicken embryo. Ecotoxicology and Environmental Safety, 170, 691-698.
Schönlau, C. , Larsson, M. , Dubocq, F. , Rotander, A. , Van der Zande, R. , Engwall, M. & Kärrman, A. (2019). Effect-Directed Analysis of Ah Receptor-Mediated Potencies in Microplastics Deployed in a Remote Tropical Marine Environment. Frontiers in Environmental Science, 7.
Jacobsen, A. V. , Nordén, M. , Engwall, M. & Scherbak, N. (2018). Effects of perfluorooctane sulfonate on genes controlling hepatic fatty acid metabolism in livers of chicken embryos. Environmental Science and Pollution Research, 25 (23), 23074-23081.
Beiras, R. , Bellas, J. , Cachot, J. , Cormier, B. , Cousin, X. , Engwall, M. , Gambardella, C. , Garaventa, F. & et al. (2018). Ingestion and contact with polyethylene microplastics does not cause acute toxicity on marine zooplankton. Journal of Hazardous Materials, 360, 452-460.
Lam, M. M. , Bülow, R. , Engwall, M. , Giesy, J. P. & Larsson, M. (2018). Methylated PACs Are More Potent than Their Parent Compounds: A Study on AhR-mediated Activity, Degradability and Mixture Interactions in the H4IIE-luc Assay. Environmental Toxicology and Chemistry, 37 (5), 1409-1419.
Larsson, M. , Lam, M. M. , van Hees, P. , Giesy, J. P. & Engwall, M. (2018). Occurrence and leachability of polycyclic aromatic compounds in contaminated soils: Chemical and bioanalytical characterization. Science of the Total Environment, 622-623, 1476-1484.
Henriksson, S. , Bjurlid, F. , Rotander, A. , Engwall, M. , Lindström, G. , Westberg, H. & Hagberg, J. (2017). Uptake and bioaccumulation of PCDD/Fs in earthworms after in situ and in vitro exposure to soil from a contaminated sawmill site. Science of the Total Environment, 580, 564-571.
Keiter, S. , Burkhard-Medicke, K. , Wellner, P. , Kais, B. , Färber, H. , Skutlarek, D. , Engwall, M. , Braunbeck, T. & et al. (2016). Does perfluorooctane sulfonate (PFOS) act as chemosensitizer in zebrafish embryos?. Science of the Total Environment, 548-549, 317-324.
Hafner, C. , Gartiser, S. , Garcia-Kaeufer, M. , Schiwy, S. , Hercher, C. , Meyer, W. , Achten, C. , Larsson, M. & et al. (2015). Investigations on sediment toxicity of German rivers applying a standardized bioassay battery. Environmental Science and Pollution Research, 22 (21), 16358-16370.
Westman, O. , Larsson, M. , Venizelos, N. , Hollert, H. & Engwall, M. (2014). An oxygenated metabolite of benzo[a]pyrene increases hepatic beta-oxidation of fatty acids in chick embryos. Environmental Science and Pollution Research, 21 (9), 6243-6251.
Eichbaum, K. , Brinkmann, M. , Buchinger, S. , Reifferscheid, G. , Hecker, M. , Giesy, J. P. , Engwall, M. , van Bavel, B. & et al. (2014). In vitro bioassays for detecting dioxin-like activity: Application potentials and limits of detection, a review. Science of the Total Environment, 487, 37-48.
Wagner, M. , Engwall, M. & Hollert, H. (2014). (Micro) Plastics and the environment. Environmental Sciences Europe, 26 (16).
Larsson, M. , Hagberg, J. , Giesy, J. P. & Engwall, M. (2014). Time-dependent relative potency factors for polycyclic aromatic hydrocarbons and their derivatives in the H4IIE-luc bioassay. Environmental Toxicology and Chemistry, 33 (4), 943-953.
Larsson, M. , Hagberg, J. , Rotander, A. , van Bavel, B. & Engwall, M. (2013). Chemical and bioanalytical characterisation of PAHs in risk assessment of remediated PAH-contaminated soils. Environmental Science and Pollution Research, 20 (12), 8511-8520.
Buitrago, B. H. , Munoz, P. F. , Ribe, V. , Larsson, M. , Engwall, M. , Wojciechowska, E. & Waara, S. (2013). Hazard assessment of sediments from a wetland system for treatment of landfill leachate using bioassays. Ecotoxicology and Environmental Safety, 97, 255-262.
Engwall, M. , Venizelos, N. , Westman, O. , Larsson, M. , Nordén, M. , Hollert, H. & Johansson, J. (2013). Polycyclic aromatic hydrocarbons (PAHs) reduce hepatic beta-oxidation of fatty acids in chick embryos. Environmental Science and Pollution Research, 20 (3), 1881-1888.
Eichbaum, K. , Brinkmann, M. , Buchinger, S. , Hecker, M. , Engwall, M. , van Bavel, B. , Reifferscheid, G. & Hollert, H. (2013). The dioRAMA project: assessment of dioxin-like activity in sediments and fish (Rutilus rutilus) in support of the ecotoxicological characterization of sediments. Journal of Soils and Sediments, 13 (4), 770-774.
Larsson, M. , Orbe, D. & Engwall, M. (2012). Ah receptor activating capacity of polycyclic aromatic hydrocarbon derivatives. Toxicology Letters, 211 (Supplement), s127.
Larsson, M. , Orbe, D. & Engwall, M. (2012). Exposure time-dependent effects on the relative potencies and additivity of PAHs in the Ah receptor-based H4IIE-luc bioassay. Environmental Toxicology and Chemistry, 31 (5), 1149-1157.
Keiter, S. , Baumann, L. , Faerber, H. , Holbech, H. , Skutlarek, D. , Engwall, M. & Braunbeck, T. (2012). Long-term effects of a binary mixture of perfluorooctane sulfonate (PFOS) and bisphenol A (BPA) in zebrafish (Danio rerio). Aquatic Toxicology, 118-119, 116-129.
Nordén, M. , Westman, O. , Venizelos, N. & Engwall, M. (2012). Perfluorooctane sulfonate increases β-oxidation of palmitic acid in chicken liver. Environmental Science and Pollution Research, 19 (5), 1859-1863.
Westman, O. , Nordén, M. , Larsson, M. , Venizelos, N. , Hollert, H. & Engwall, M. (2012). Reduced beta-oxidation in avian following exposure of polycyclic aromatic hydrocarbons. Toxicology Letters, 211 (Supplement), s86-s87.
Hinger, G. , Brinkmann, M. , Bluhm, K. , Sagner, A. , Takner [Olsman], H. , Eisentraeger, A. , Braunbeck, T. , Engwall, M. & et al. (2011). Some heterocyclic aromatic compounds are Ah receptor agonists in the DR-CALUX assay and the EROD assay with RTL-W1 cells. Environmental Science and Pollution Research, 18 (8), 1297-1304.
Westman, O. , Nordén, M. , Venizelos, N. & Engwall, M. (2010). Effects of perfluorinated compounds on hepatic fatty acid oxidation in avian embryos using a tritium release assay. In Vivo, 24 (3), 363-364.
Nordén, M. , Halldin, K. & Engwall, M. (2010). Gene expression analysis of chicken during development subsequent to PFOS and PFOA exposure. In Vivo, 24 (3), 358-358.
Andersson, E. , Rotander, A. , von Kronhelm, T. , Berggren, A. , Ivarsson, P. , Hollert, H. & Engwall, M. (2009). AhR agonist and genotoxicant bioavailability in a PAH-contaminated soil undergoing biological treatment. Environmental Science and Pollution Research, 16 (5), 521-530.
Hollert, H. , Keiter, S. , Böttcher, M. , Grund, S. , Seitz, N. , Otte, J. , Bluhm, K. , Wurm, K. & et al. (2009). Eine Weight-of-Evidence-Studie zur Bewertung der Sedimentbelastung und des Fischrückgangs in der Oberen Donau [Assessing sediments and fish health using a weight-of-evidence approach : in search for the causes of fish decline in the Danube river]. Umweltwissenschaften und Schadstoff-Forschung, 21 (3), 260-263.
Otte, J. C. , Andersson, C. , Abrahamson, A. , Olsman Takner, H. , Keiter, S. , Engwall, M. , Hollert, H. & Brunström, B. (2008). A bioassay approach to determine the dioxin-like activity in sediment extracts from the Danube River: ethoxyresorufin-O-deethylase induction in gill filaments and liver of three-spined sticklebacks (Gasterosteus aculeatus L.). Environment International, 34 (8), 1176-1184.
Keiter, S. , Grund, S. , van Bavel, B. , Hagberg, J. , Engwall, M. , Ulrike, K. , Klempt, M. , Manz, W. & et al. (2008). Activities and identification of aryl hydrocarbon receptor agonists in sediments from the Danube river. Analytical and Bioanalytical Chemistry, 390 (8), 2009-2019.
Keiter, S. , Grund, S. , van Bavel, B. , Hagberg, J. , Engwall, M. , Kammann, U. , Klempt, M. , Manz, W. & et al. (2008). Activities and identification of aryl hydrocarbon receptor agonists in sediments from the Danube river. Analytical and Bioanalytical Chemistry, 390 (8), 2009-2019.
Wölz, J. , Engwall, M. , Maletz, S. , Olsman Takner, H. , van Bavel, B. , Kammann, U. , Klempt, M. , Weber, R. & et al. (2008). Changes in toxicity and Ah receptor agonist activity of suspended particulate matter during flood events at the rivers Neckar and Rhine - a mass balance approach using in vitro methods and chemical analysis. Environmental Science and Pollution Research, 15 (7), 536-553.
van Hees, P. A. W. , Elgh-Dalgren, K. , Engwall, M. & von Kronhelm, T. (2008). Re-cycling of Remediated Soil in Sweden: An Environmental Advantage?. Resources, Conservation and Recycling, 52 (12), 1349-1361.
Olsman, H. , Schnurer, A. , Bjornfoth, H. , van Bavel, B. & Engwall, M. (2007). Fractionation and determination of Ah receptor (AhR) agonists in organic waste after anaerobic biodegradation and in batch experiments with PCB and decaBDE. Environmental Science and Pollution Research, 14 (1), 36-43.
Bergknut, M. , Kucera, A. , Frech, K. , Andersson, E. , Engwall, M. , Rannug, U. , Koci, V. , Andersson, P. L. & et al. (2007). Identification of potentially toxic compounds in complex extracts of environmental samples using gas chromatography-mass spectrometry and multivariate data analysis. Environmental Toxicology and Chemistry, 26 (2), 208-217.
Jernbro, S. , Suares Rocha, P. , Keiter, S. , Skutlarek, D. , Färber, H. , Jones, P. D. , Giesy, J. P. , Hollert, H. & et al. (2007). Perfluorooctane Sulfonate Increases the Genotoxicity of Cyclophosphamide in the Micronucleus Assay with V79 Cells: Further Proof of Alterations in Cell Membrane Properties Caused by PFOS. Environmental Science and Pollution Research, 14 (2), 85-87.
Olsman [Takner], H. , Engwall, M. , Kammann, U. , Klempt, M. , Otte, J. , van Bavel, B. & Hollert, H. (2007). Relative differences in aryl hydrocarbon receptor-mediated response for 18 polybrominated and mixed halogenated dibenzo-p-dioxins and -furans in cell lines from four different species. Environmental Toxicology and Chemistry, 26 (11), 2448-2454.
Olsman, H. , Hagberg, J. , Kalbin, G. , Julander, A. , van Bavel, B. , Strid, Å. , Tysklind, M. & Engwall, M. (2006). Ah receptor agonists in UV-exposed toluene solutions of decabromodiphenyl ether (decaBDE) and in soils contaminated with polybrominated diphenyl ethers (PBDEs). Environmental Science and Pollution Research, 13 (3), 161-169.
Hagberg, J. , Olsman, H. , van Bavel, B. , Engwall, M. & Lindström, G. (2006). Chemical and toxicological characterisation of PBDFs from photolytic decomposition of decaBDE in toluene. Environment International, 32 (7), 851-857.
Julander, A. , Westberg, H. , Engwall, M. & van Bavel, B. (2005). Distribution of brominated flame retardants in different dust fractions in air from an electronics recycling facility. Science of the Total Environment, 350 (1-3), 151-160.
Kalbin, G. , Li, S. , Olsman, H. , Pettersson, M. , Engwall, M. & Strid, Å. (2005). Effects of UV-B in biological and chemical systems: equipment for wavelength dependence determination. Journal of Biochemical and Biophysical Methods, 65 (1), 1-12.
Julander, A. , Karlsson, M. , Hagström, K. , Ohlson, C. , Engwall, M. , Bryngelsson, I. , Westberg, H. & van Bavel, B. (2005). Polybrominated diphenyl ethers: plasma levels and thyroid status of workers at an electronic recycling facility. International Archives of Occupational and Environmental Health, 78 (7), 584-592.
Klee, N. , Gustavsson, L. , Kosmehl, T. , Engwall, M. , Erdinger, L. , Braunbeck, T. & Hollert, H. (2004). Changes in toxicity and genotoxicity of industrial sewage sludge samples containing nitro- and amino-aromatic compounds following treatment in bioreactors with different oxygen regimes. Environmental Science and Pollution Research, 11 (5), 313-320.
Gustavsson, L. , Klee, N. , Olsman, H. , Hollert, H. & Engwall, M. (2004). Fate of Ah receptor agonists during biological treatment of an industrial sludge containing explosives and pharmaceutical residues. Environmental Science and Pollution Research, 11 (6), 379-386.
Pettersson-Julander, A. , van Bavel, B. , Engwall, M. & Westberg, H. (2004). Personal air sampling and analysis of polybrominated diphenyl ethers and other bromine containing compounds at an electronic recycling facility in Sweden. Journal of Environmental Monitoring, 6 (11), 874-880.
Pettersson, A. , van Bavel, B. , Engwall, M. & Jimenez, B. (2004). Polybrominated diphenylethers and methoxylated tetrabromodiphenylethers in cetaceans from the Mediterranean Sea. Archives of Environmental Contamination and Toxicology, 47 (4), 542-550.
Hollert, H. , Dürr, M. , Olsman, H. , Halldin, K. , van Bavel, B. , Brack, W. , Tysklind, M. , Engwall, M. & et al. (2002). Biological and chemical determination of dioxin-like compounds in sediments by means of a sediment triad approach in the catchment area of the River Neckar. Ecotoxicology, 11 (5), 323-336.
Olsman, H. , van Bavel, B. , Kalbin, G. , Pettersson, A. , Stenlund, S. , Strid, Å. & Engwall, M. (2002). Formation of dioxin-like compounds as photoproducts of decarbominated diphenyl ether (deBDE) during UV-irradiation. Organohalogen Compounds, 58, 41-44.
Engwall, M. , Broman, D. , Näf, C. , Zebuhr, Y. & Brunström, B. (1997). Dioxin-like compounds in HPLC-fractionated extracts of marine samples from the east and west coast of Sweden: bioassay- and instrumentally-derived TCDD equivalents. Marine Pollution Bulletin, 34 (12), 1032-1040.
Engwall, M. , Broman, D. , Dencker, L. , Näf, C. , Zebuhr, Y. & Brunström, B. (1997). Toxic potencies of extracts of sediment and settling particulate matter collected in the recipient of a bleached pulp mill effluent before and after abandoning chlorine bleaching. Environmental Toxicology and Chemistry, 16 (6), 1187-1194.
Engwall, M. , Broman, D. , Ishaq, R. , Näf, C. , Zebuhr, Y. & Brunström, B. (1996). Toxic potencies of lipophilic extracts from sediments and settling particulate matter (SPM) collected in a PCB-contaminated river system. Environmental Toxicology and Chemistry, 15 (2), 213-222.
Brunström, B. , Engwall, M. , Hjelm, K. , Lindqvist, L. & Zebuhr, Y. (1995). EROD induction in cultured chick embryo liver: a sensitive bioassay for dioxin-like environmental pollutants. Environmental Toxicology and Chemistry, 14 (5), 837-842.
Håkansson, H. , Sundin, P. , Andersson, T. , Brunström, B. , Dencker, L. , Engwall, M. , Ewald, G. , Gilek, M. & et al. (1991). In vivo and in vitro toxicity of fractionated fish lipids, with particular regard to their content of chlorinated organic compounds. Pharmacology and Toxicology, 69 (6), 459-471.

Articles, reviews/surveys

Legradi, J. B. , Di Paolo, C. , Kraak, M. H. S. , van der Geest, H. G. , Schymanski, E. L. , Williams, A. J. , Dingemans, M. M. L. , Massei, R. & et al. (2018). An ecotoxicological view on neurotoxicity assessment. Environmental Sciences Europe, 30.

Manuscripts

Westman, O. , Larsson, M. , Venizelos, N. , Hollert, H. & Engwall, M. An oxygenated metabolite of benzo[a]pyrene increases hepatic β-oxidation of fatty acids in chick embryos.
Larsson, M. , Hagberg, J. , Rotander, A. , van Bavel, B. & Engwall, M. Chemical and bioanalytical characterisation of PAHs in risk assessment of remediated PAH-contaminated soils.
Schönlau, C. , Karlsson, T. , Rotander, A. , Nilsson, H. , Engwall, M. , van Bavel, B. & Kärrman, A. Microplastics in sea-surface waters surrounding Sweden sampled by manta trawl and in-situ pump.
Julander, A. , Karlsson, M. , Hagström, K. , Ohlson, C. G. , Engwall, M. , Bryngelsson, I. , Westberg, H. & van Bavel, B. Polybrominated diphenylethers and thyroid hormone status in human plasma of workers at electronic recycling facility.
Lam, M. M. , Engwall, M. , Denison, M. S. , Giesy, J. P. & Larsson, M. Polyoxymethylene (POM) is a suitable tool for effect-based hazard assessment of PAC-contaminated soil.

Reports

Kärrman, A. , Schönlau, C. & Engwall, M. (2016). Exposure and effects of microplastics on wildlife: A review of existing data. Örebro: Örebro universitet.
Engwall, M. & Larsson, M. (2009). Bioanalys av organiska föroreningars biotillgänglighet: tillämpning i sanerade massor. Stockholm: Naturvårdsverket (Rapport 5931).