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Magnus Engwall

Tjänstetitel: Professor Organisation: Institutionen för naturvetenskap och teknik

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Telefon: 019 303606

Rum: B3305

Magnus Engwall

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Om Magnus Engwall

My research is directed towards studying receptor-mediated effects of organic environmental pollutants on living organisms. I lead several research projects using mechanism-specific bioassays for characterisation of complex mixtures of receptor-acting toxicants. These include toxicological characterisation and risk assessment of contaminated soil and sediment, marine plastic, and other complex mixtures. I am also research director of Man-Technology-Environment research center.

Forskningsprojekt

Forskargrupper

Publikationer

Publikationer

Artiklar i tidskrifter |  Artiklar, forskningsöversikter |  Manuskript |  Rapporter | 

Artiklar i tidskrifter

Schönlau, C. , Larsson, M. , Lam, M. M. , Engwall, M. , Giesy, J. P. , Rochman, C. & Kärrman, A. (2019). Aryl hydrocarbon receptor-mediated potencies in field-deployed plastics vary by type of polymer. Environmental science and pollution research international, 26 (9), 9097-9088.
Geng, D. , Musse, A. A. , Wigh, V. , Carlsson, C. , Engwall, M. , Oresic, M. , Scherbak, N. & Hyötyläinen, T. (2019). Effect of perfluorooctanesulfonic acid (PFOS) on the liver lipid metabolism of the developing chicken embryo. Ecotoxicology and Environmental Safety, 170, 691-698.
Schönlau, C. , Larsson, M. , Dubocq, F. , Rotander, A. , Van der Zande, R. , Engwall, M. & Kärrman, A. (2019). Effect-Directed Analysis of Ah Receptor-Mediated Potencies in Microplastics Deployed in a Remote Tropical Marine Environment. Frontiers in Environmental Science, 7.
Jacobsen, A. V. , Nordén, M. , Engwall, M. & Scherbak, N. (2018). Effects of perfluorooctane sulfonate on genes controlling hepatic fatty acid metabolism in livers of chicken embryos. Environmental science and pollution research international, 25 (23), 23074-23081.
Beiras, R. , Bellas, J. , Cachot, J. , Cormier, B. , Cousin, X. , Engwall, M. , Gambardella, C. , Garaventa, F. & et al. (2018). Ingestion and contact with polyethylene microplastics does not cause acute toxicity on marine zooplankton. Journal of Hazardous Materials, 360, 452-460.
Lam, M. M. , Bülow, R. , Engwall, M. , Giesy, J. P. & Larsson, M. (2018). Methylated PACs Are More Potent than Their Parent Compounds: A Study on AhR-mediated Activity, Degradability and Mixture Interactions in the H4IIE-luc Assay. Environmental Toxicology and Chemistry, 37 (5), 1409-1419.
Larsson, M. , Lam, M. M. , van Hees, P. , Giesy, J. P. & Engwall, M. (2018). Occurrence and leachability of polycyclic aromatic compounds in contaminated soils: Chemical and bioanalytical characterization. Science of the Total Environment, 622-623, 1476-1484.
Henriksson, S. , Bjurlid, F. , Rotander, A. , Engwall, M. , Lindström, G. , Westberg, H. & Hagberg, J. (2017). Uptake and bioaccumulation of PCDD/Fs in earthworms after in situ and in vitro exposure to soil from a contaminated sawmill site. Science of the Total Environment, 580, 564-571.
Nordén, M. , Berger, U. & Engwall, M. (2016). Developmental toxicity of PFOS and PFOA in great cormorant (Phalacrocorax carbo sinensis), herring gull (Larus argentatus) and chicken (Gallus gallus domesticus). Environmental science and pollution research international, 23 (11), 10855-10862.
Keiter, S. , Burkhard-Medicke, K. , Wellner, P. , Kais, B. , Färber, H. , Skutlarek, D. , Engwall, M. , Braunbeck, T. & et al. (2016). Does perfluorooctane sulfonate (PFOS) act as chemosensitizer in zebrafish embryos?. Science of the Total Environment, 548-549, 317-324.
Hafner, C. , Gartiser, S. , Garcia-Kaeufer, M. , Schiwy, S. , Hercher, C. , Meyer, W. , Achten, C. , Larsson, M. & et al. (2015). Investigations on sediment toxicity of German rivers applying a standardized bioassay battery. Environmental science and pollution research international, 22 (21), 16358-16370.
Westman, O. , Larsson, M. , Venizelos, N. , Hollert, H. & Engwall, M. (2014). An oxygenated metabolite of benzo[a]pyrene increases hepatic beta-oxidation of fatty acids in chick embryos. Environmental science and pollution research international, 21 (9), 6243-6251.
Eichbaum, K. , Brinkmann, M. , Buchinger, S. , Reifferscheid, G. , Hecker, M. , Giesy, J. P. , Engwall, M. , van Bavel, B. & et al. (2014). In vitro bioassays for detecting dioxin-like activity: Application potentials and limits of detection, a review. Science of the Total Environment, 487, 37-48.
Wagner, M. , Engwall, M. & Hollert, H. (2014). (Micro) Plastics and the environment. Environmental Sciences Europe, 26 (16).
Larsson, M. , Hagberg, J. , Giesy, J. P. & Engwall, M. (2014). Time-dependent relative potency factors for polycyclic aromatic hydrocarbons and their derivatives in the H4IIE-luc bioassay. Environmental Toxicology and Chemistry, 33 (4), 943-953.
Larsson, M. , Hagberg, J. , Rotander, A. , van Bavel, B. & Engwall, M. (2013). Chemical and bioanalytical characterisation of PAHs in risk assessment of remediated PAH-contaminated soils. Environmental science and pollution research international, 20 (12), 8511-8520.
Buitrago, B. H. , Munoz, P. F. , Ribe, V. , Larsson, M. , Engwall, M. , Wojciechowska, E. & Waara, S. (2013). Hazard assessment of sediments from a wetland system for treatment of landfill leachate using bioassays. Ecotoxicology and Environmental Safety, 97, 255-262.
Nordén, M. , Berger, U. & Engwall, M. (2013). High levels of perfluoroalkyl acids in eggs and embryo livers of great cormorant (Phalacrocorax carbo sinensis) and herring gull (Larus argentatus) from Lake Vanern, Sweden. Environmental science and pollution research international, 20 (11), 8021-8030.
Engwall, M. , Venizelos, N. , Westman, O. , Larsson, M. , Nordén, M. , Hollert, H. & Johansson, J. (2013). Polycyclic aromatic hydrocarbons (PAHs) reduce hepatic beta-oxidation of fatty acids in chick embryos. Environmental science and pollution research international, 20 (3), 1881-1888.
Eichbaum, K. , Brinkmann, M. , Buchinger, S. , Hecker, M. , Engwall, M. , van Bavel, B. , Reifferscheid, G. & Hollert, H. (2013). The dioRAMA project: assessment of dioxin-like activity in sediments and fish (Rutilus rutilus) in support of the ecotoxicological characterization of sediments. Journal of Soils and Sediments, 13 (4), 770-774.
Larsson, M. , Orbe, D. & Engwall, M. (2012). Ah receptor activating capacity of polycyclic aromatic hydrocarbon derivatives. Toxicology Letters, 211 (Supplement), s127.
Larsson, M. , Orbe, D. & Engwall, M. (2012). Exposure time-dependent effects on the relative potencies and additivity of PAHs in the Ah receptor-based H4IIE-luc bioassay. Environmental Toxicology and Chemistry, 31 (5), 1149-1157.
Keiter, S. , Baumann, L. , Faerber, H. , Holbech, H. , Skutlarek, D. , Engwall, M. & Braunbeck, T. (2012). Long-term effects of a binary mixture of perfluorooctane sulfonate (PFOS) and bisphenol A (BPA) in zebrafish (Danio rerio). Aquatic Toxicology, 118-119, 116-129.
Nordén, M. , Westman, O. , Venizelos, N. & Engwall, M. (2012). Perfluorooctane sulfonate increases β-oxidation of palmitic acid in chicken liver. Environmental science and pollution research international, 19 (5), 1859-1863.
Westman, O. , Nordén, M. , Larsson, M. , Venizelos, N. , Hollert, H. & Engwall, M. (2012). Reduced beta-oxidation in avian following exposure of polycyclic aromatic hydrocarbons. Toxicology Letters, 211 (Supplement), s86-s87.
Hinger, G. , Brinkmann, M. , Bluhm, K. , Sagner, A. , Takner [Olsman], H. , Eisentraeger, A. , Braunbeck, T. , Engwall, M. & et al. (2011). Some heterocyclic aromatic compounds are Ah receptor agonists in the DR-CALUX assay and the EROD assay with RTL-W1 cells. Environmental science and pollution research international, 18 (8), 1297-1304.
Westman, O. , Nordén, M. , Venizelos, N. & Engwall, M. (2010). Effects of perfluorinated compounds on hepatic fatty acid oxidation in avian embryos using a tritium release assay. In Vivo, 24 (3), 363-364.
Nordén, M. , Halldin, K. & Engwall, M. (2010). Gene expression analysis of chicken during development subsequent to PFOS and PFOA exposure. In Vivo, 24 (3), 358-358.
Andersson, E. , Rotander, A. , von Kronhelm, T. , Berggren, A. , Ivarsson, P. , Hollert, H. & Engwall, M. (2009). AhR agonist and genotoxicant bioavailability in a PAH-contaminated soil undergoing biological treatment. Environmental science and pollution research international, 16 (5), 521-530.
Hollert, H. , Keiter, S. , Böttcher, M. , Grund, S. , Seitz, N. , Otte, J. , Bluhm, K. , Wurm, K. & et al. (2009). Eine Weight-of-Evidence-Studie zur Bewertung der Sedimentbelastung und des Fischrückgangs in der Oberen Donau [Assessing sediments and fish health using a weight-of-evidence approach : in search for the causes of fish decline in the Danube river]. Umweltwissenschaften und Schadstoff-Forschung, 21 (3), 260-263.
Otte, J. C. , Andersson, C. , Abrahamson, A. , Olsman Takner, H. , Keiter, S. , Engwall, M. , Hollert, H. & Brunström, B. (2008). A bioassay approach to determine the dioxin-like activity in sediment extracts from the Danube River: ethoxyresorufin-O-deethylase induction in gill filaments and liver of three-spined sticklebacks (Gasterosteus aculeatus L.). Environment International, 34 (8), 1176-1184.
Keiter, S. , Grund, S. , van Bavel, B. , Hagberg, J. , Engwall, M. , Ulrike, K. , Klempt, M. , Manz, W. & et al. (2008). Activities and identification of aryl hydrocarbon receptor agonists in sediments from the Danube river. Analytical and Bioanalytical Chemistry, 390 (8), 2009-2019.
Keiter, S. , Grund, S. , van Bavel, B. , Hagberg, J. , Engwall, M. , Kammann, U. , Klempt, M. , Manz, W. & et al. (2008). Activities and identification of aryl hydrocarbon receptor agonists in sediments from the Danube river. Analytical and Bioanalytical Chemistry, 390 (8), 2009-2019.
Wölz, J. , Engwall, M. , Maletz, S. , Olsman Takner, H. , van Bavel, B. , Kammann, U. , Klempt, M. , Weber, R. & et al. (2008). Changes in toxicity and Ah receptor agonist activity of suspended particulate matter during flood events at the rivers Neckar and Rhine - a mass balance approach using in vitro methods and chemical analysis. Environmental science and pollution research international, 15 (7), 536-553.
van Hees, P. A. W. , Elgh-Dalgren, K. , Engwall, M. & von Kronhelm, T. (2008). Re-cycling of Remediated Soil in Sweden: An Environmental Advantage?. Resources, Conservation and Recycling, 52 (12), 1349-1361.
Olsman, H. , Schnurer, A. , Bjornfoth, H. , van Bavel, B. & Engwall, M. (2007). Fractionation and determination of Ah receptor (AhR) agonists in organic waste after anaerobic biodegradation and in batch experiments with PCB and decaBDE. Environmental science and pollution research international, 14 (1), 36-43.
Bergknut, M. , Kucera, A. , Frech, K. , Andersson, E. , Engwall, M. , Rannug, U. , Koci, V. , Andersson, P. L. & et al. (2007). Identification of potentially toxic compounds in complex extracts of environmental samples using gas chromatography-mass spectrometry and multivariate data analysis. Environmental Toxicology and Chemistry, 26 (2), 208-217.
Jernbro, S. , Suares Rocha, P. , Keiter, S. , Skutlarek, D. , Färber, H. , Jones, P. D. , Giesy, J. P. , Hollert, H. & et al. (2007). Perfluorooctane Sulfonate Increases the Genotoxicity of Cyclophosphamide in the Micronucleus Assay with V79 Cells: Further Proof of Alterations in Cell Membrane Properties Caused by PFOS. Environmental science and pollution research international, 14 (2), 85-87.
Olsman [Takner], H. , Engwall, M. , Kammann, U. , Klempt, M. , Otte, J. , van Bavel, B. & Hollert, H. (2007). Relative differences in aryl hydrocarbon receptor-mediated response for 18 polybrominated and mixed halogenated dibenzo-p-dioxins and -furans in cell lines from four different species. Environmental Toxicology and Chemistry, 26 (11), 2448-2454.
Olsman, H. , Hagberg, J. , Kalbin, G. , Julander, A. , van Bavel, B. , Strid, Å. , Tysklind, M. & Engwall, M. (2006). Ah receptor agonists in UV-exposed toluene solutions of decabromodiphenyl ether (decaBDE) and in soils contaminated with polybrominated diphenyl ethers (PBDEs). Environmental science and pollution research international, 13 (3), 161-169.
Hagberg, J. , Olsman, H. , van Bavel, B. , Engwall, M. & Lindström, G. (2006). Chemical and toxicological characterisation of PBDFs from photolytic decomposition of decaBDE in toluene. Environment International, 32 (7), 851-857.
Julander, A. , Westberg, H. , Engwall, M. & van Bavel, B. (2005). Distribution of brominated flame retardants in different dust fractions in air from an electronics recycling facility. Science of the Total Environment, 350 (1-3), 151-160.
Kalbin, G. , Li, S. , Olsman, H. , Pettersson, M. , Engwall, M. & Strid, Å. (2005). Effects of UV-B in biological and chemical systems: equipment for wavelength dependence determination. Journal of Biochemical and Biophysical Methods, 65 (1), 1-12.
Julander, A. , Karlsson, M. , Hagström, K. , Ohlson, C. , Engwall, M. , Bryngelsson, I. , Westberg, H. & van Bavel, B. (2005). Polybrominated diphenyl ethers: plasma levels and thyroid status of workers at an electronic recycling facility. International Archives of Occupational and Environmental Health, 78 (7), 584-592.
Klee, N. , Gustavsson, L. , Kosmehl, T. , Engwall, M. , Erdinger, L. , Braunbeck, T. & Hollert, H. (2004). Changes in toxicity and genotoxicity of industrial sewage sludge samples containing nitro- and amino-aromatic compounds following treatment in bioreactors with different oxygen regimes. Environmental science and pollution research international, 11 (5), 313-320.
Gustavsson, L. , Klee, N. , Olsman, H. , Hollert, H. & Engwall, M. (2004). Fate of Ah receptor agonists during biological treatment of an industrial sludge containing explosives and pharmaceutical residues. Environmental science and pollution research international, 11 (6), 379-386.
Pettersson-Julander, A. , van Bavel, B. , Engwall, M. & Westberg, H. (2004). Personal air sampling and analysis of polybrominated diphenyl ethers and other bromine containing compounds at an electronic recycling facility in Sweden. Journal of Environmental Monitoring, 6 (11), 874-880.
Pettersson, A. , van Bavel, B. , Engwall, M. & Jimenez, B. (2004). Polybrominated diphenylethers and methoxylated tetrabromodiphenylethers in cetaceans from the Mediterranean Sea. Archives of Environmental Contamination and Toxicology, 47 (4), 542-550.
Hollert, H. , Dürr, M. , Olsman, H. , Halldin, K. , van Bavel, B. , Brack, W. , Tysklind, M. , Engwall, M. & et al. (2002). Biological and chemical determination of dioxin-like compounds in sediments by means of a sediment triad approach in the catchment area of the River Neckar. Ecotoxicology, 11 (5), 323-336.
Olsman, H. , van Bavel, B. , Kalbin, G. , Pettersson, A. , Stenlund, S. , Strid, Å. & Engwall, M. (2002). Formation of dioxin-like compounds as photoproducts of decarbominated diphenyl ether (deBDE) during UV-irradiation. Organohalogen Compounds, 58, 41-44.
Engwall, M. , Broman, D. , Näf, C. , Zebuhr, Y. & Brunström, B. (1997). Dioxin-like compounds in HPLC-fractionated extracts of marine samples from the east and west coast of Sweden: bioassay- and instrumentally-derived TCDD equivalents. Marine Pollution Bulletin, 34 (12), 1032-1040.
Engwall, M. , Broman, D. , Dencker, L. , Näf, C. , Zebuhr, Y. & Brunström, B. (1997). Toxic potencies of extracts of sediment and settling particulate matter collected in the recipient of a bleached pulp mill effluent before and after abandoning chlorine bleaching. Environmental Toxicology and Chemistry, 16 (6), 1187-1194.
Engwall, M. , Broman, D. , Ishaq, R. , Näf, C. , Zebuhr, Y. & Brunström, B. (1996). Toxic potencies of lipophilic extracts from sediments and settling particulate matter (SPM) collected in a PCB-contaminated river system. Environmental Toxicology and Chemistry, 15 (2), 213-222.
Brunström, B. , Engwall, M. , Hjelm, K. , Lindqvist, L. & Zebuhr, Y. (1995). EROD induction in cultured chick embryo liver: a sensitive bioassay for dioxin-like environmental pollutants. Environmental Toxicology and Chemistry, 14 (5), 837-842.
Håkansson, H. , Sundin, P. , Andersson, T. , Brunström, B. , Dencker, L. , Engwall, M. , Ewald, G. , Gilek, M. & et al. (1991). In vivo and in vitro toxicity of fractionated fish lipids, with particular regard to their content of chlorinated organic compounds. Pharmacology and Toxicology, 69 (6), 459-471.

Artiklar, forskningsöversikter

Legradi, J. B. , Di Paolo, C. , Kraak, M. H. S. , van der Geest, H. G. , Schymanski, E. L. , Williams, A. J. , Dingemans, M. M. L. , Massei, R. & et al. (2018). An ecotoxicological view on neurotoxicity assessment. Environmental Sciences Europe, 30.

Manuskript

Westman, O. , Larsson, M. , Venizelos, N. , Hollert, H. & Engwall, M. An oxygenated metabolite of benzo[a]pyrene increases hepatic β-oxidation of fatty acids in chick embryos.
Larsson, M. , Hagberg, J. , Rotander, A. , van Bavel, B. & Engwall, M. Chemical and bioanalytical characterisation of PAHs in risk assessment of remediated PAH-contaminated soils.
Schönlau, C. , Karlsson, T. , Rotander, A. , Nilsson, H. , Engwall, M. , van Bavel, B. & Kärrman, A. Microplastics in sea-surface waters surrounding Sweden sampled by manta trawl and in-situ pump.
Julander, A. , Karlsson, M. , Hagström, K. , Ohlson, C. G. , Engwall, M. , Bryngelsson, I. , Westberg, H. & van Bavel, B. Polybrominated diphenylethers and thyroid hormone status in human plasma of workers at electronic recycling facility.
Lam, M. M. , Engwall, M. , Denison, M. S. , Giesy, J. P. & Larsson, M. Polyoxymethylene (POM) is a suitable tool for effect-based hazard assessment of PAC-contaminated soil.

Rapporter

Kärrman, A. , Schönlau, C. & Engwall, M. (2016). Exposure and effects of microplastics on wildlife: A review of existing data. Örebro: Örebro universitet.
Engwall, M. & Larsson, M. (2009). Bioanalys av organiska föroreningars biotillgänglighet: tillämpning i sanerade massor. Stockholm: Naturvårdsverket (Rapport 5931).