Mulugeta Melkie Zegeye

Articles in journals

• Kumawat, A. K. , Zegeye, M. M. , Paramel Varghese, G. , Baumgartner, R. , Gisterå, A. , Amegavie, O. , Hellberg, S. , Jin, H. & et al. (2022). Inhibition of IL17A Using an Affibody Molecule Attenuates Inflammation in ApoE-Deficient Mice. Frontiers in Cardiovascular Medicine, 9.
• Lindkvist, M. , Zegeye, M. M. , Grenegård, M. & Ljungberg, L. (2022). Pleiotropic, Unique and Shared Responses Elicited by IL-6 Family Cytokines in Human Vascular Endothelial Cells. International Journal of Molecular Sciences, 23 (3).
• Zegeye, M. M. , Andersson, J. S. O. , Wennberg, P. , Repsilber, D. , Sirsjö, A. & Ljungberg, L. (2021). IL-6 as a Mediator of the Association Between Traditional Risk Factors and Future Myocardial Infarction: A Nested Case-Control Study. Arteriosclerosis, Thrombosis and Vascular Biology, 41 (4), 1570-1579.
• Zegeye, M. M. , Kumawat, A. K. , Matic, L. , Lengquist, M. , Hyderi, A. , Hedin, U. , Sirsjö, A. & Ljungberg, L. (2021). IL-6 trans-signaling regulates vascular endothelial laminin profile and inflammatory responses: Possible mechanism for immune cell recruitment during atherosclerosis?. Atherosclerosis, 331, E61-E61.
• Ljungberg, L. , Zegeye, M. M. , Kardeby, C. , Fälker, K. , Repsilber, D. & Sirsjö, A. (2020). Global Transcriptional Profiling Reveals Novel Autocrine Functions of Interleukin 6 in Human Vascular Endothelial Cells. Mediators of Inflammation, 2020.
• Zegeye, M. M. , Andersson, B. , Sirsjö, A. & Ljungberg, L. U. (2020). IL-6 trans-Signaling Impairs Sprouting Angiogenesis by Inhibiting Migration, Proliferation and Tube Formation of Human Endothelial Cells.. Cells, 9 (6).
• Zegeye, M. M. , Lindkvist, M. , Fälker, K. , Kumawat, A. K. , Paramel Varghese, G. , Grenegård, M. , Sirsjö, A. & Ljungberg, L. U. (2018). Activation of the JAK/STAT3 and PI3K/AKT pathways are crucial for IL-6 trans-signaling-mediated pro-inflammatory response in human vascular endothelial cells. Cell Communication and Signaling, 16 (1).

Doctoral theses, comprehensive summaries

• Zegeye, M. M. (2021). Interleukin-6 Signaling Pathways in Human Vascular Endothelial Cells: Molecular Mechanisms and Associations to Atherosclerosis. (Doctoral dissertation). (Comprehensive summary) Örebro: Örebro University.

Manuscripts

• Lindkvist, M. , Zegeye, M. M. , Sirsjö, A. , Grenegård, M. & Ljungberg, L. U. Comparative evaluation of gp130 signalling cytokines in human endothelial cells : evidence for both specific and overlapping molecular responses.
• Zegeye, M. M. , Kumawat, A. K. , Matic, L. , Lengquist, M. , Hayderi, A. , Hedin, U. , Sirsjö, A. & Ljungberg, L. U. IL-6 trans-signaling regulates vascular endothelial laminin profile and inflammatory responses : possible mechanism for immune cell recruitment during atherosclerosis?.
• Zegeye, M. M. , Andersson, J. S. , Wennberg, P. , Repsilber, D. , Sirsjö, A. & Ljungberg, L. Interleukin-6 as a mediator of the association between traditional risk factors and future Myocardial Infarction : A nested case-control study.