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Research Projects

Integrative bioinformatics: combining clinical, physiological, brain imaging and molecular profiles

About this project

About this project

Project information

Projekt Status

In progress

Contact

Dirk Repsilber

Research Subject

Research environments

The aim of this project is to make use of a combination of different kinds of data to detect subgroups in patient cohorts, and to develop diagnostic biosignatures. Datasets include functional brain imaging with paradigms aiming to elucidate brain-gut-interactions in patients suffering from IBS and healthy controls; biopsy permeability markers; gut microbiota; cytokines, gut hormones and stress markers measured in blood and saliva; metabolomics profiles in blood and fecal samples; and proteomics as well as gene expression profiles from small and large bowel biopsies. Subjects' nutritional habits, lifestyle parameters, and psychological status are scores with validated questionnaire tools.

Researchers

Research Teams

Research Teams