Nutrition-Gut-Brain Interactions Research Centre (NGBI) Research projects at NGBI Research projects Active projects ADAPTide: decrypting sustainable and responsive nutrition by mapping the effects of plant-based foods on metabolic profiling Biosignatures and functional network structures Butyrate-promoting dietary fibres as a potential strategy for the prevention of type-2 diabetes Comparing the efficacy of encapsulated and non-encapsulated probiotics to affect brain function Compositional analysis of the human gut microbiota along the entire large intestine Effect of serotonergic stimulation on the gut-brain axis in irritable bowel syndrome patients compared with healthy subjects applying functional brain imaging Establishing a novel gut-brain axis model Exploring the probiotic and postbiotic effect of Akkermansia muciniphila on intestinal barrier function in patients with Parkinson's disease - applying Ussing chambers and electron microscopy techniques Identification of dietary fibres that promotes butyrate production ImprUV+ - An analytical framework to explore the effects of UV during plant growth on human health Interaction between dietary protein and fibre fermentation - its functional consequences Investigation of endocrine-disrupting chemicals as contributors to progression of metabolic dysfunction-associated steatotic liver disease LITMUS Mat i Sverige Microbes inside Mode of action of butyrate in the human colon Network medicine and systems biological approaches to modeling inflammation NORDTREAT PAN Protein - plant-based proteins contributing to a healthy and sustainable diet POPgut - The impact of persistent organic pollutants exposure on gut health Proteome signatures in IBD Systematic modelling: quantitative and semi-qualitative implementations of nutrition-microbe-gut-blood-brain interactions regarding the role of butyrate The effects of fermentable dietary fibre supplementation on intestinal permeability and inflammation in microscopic colitis To determine the butyrate transport capacity in vitro and in tissue samples from healthy individuals and from patients with digestive disorders Unpuzzle - Unravelling molecular motifs from dietary fibers responsible for interaction with recognition receptors in human cells Completed projects Ageing and the gastrointestinal microbiome: effects on immunology and cognitive function Blood-based metabolomics to predict severity and patient outcomes in traumatic brain injury (meTBI) Development of a comprehensive elderly cohort Development of an in vivo butyrate sensor Dietary Fibers supporting Gut and Immune Function - from polysaccharide compound to health claim (FibeBiotics) Effect of aryl hydrocarbon receptor (AhR) ligands on human colonic intraepithelial lymphocytes Effect of the enzyme AN-PEP on gluten degradation in gluten-sensitive individuals Efficacy of dietary supplementation with Lactobacilllus reuteri for digestive health in an elderly population (ELROY) Faecal microbial transplantation (FMT) in IBS Faecal microbiota transfer in microscopic colitis Functional characterization of tyrosine, alanine and tryptophan transport in human fibroblast cells Functional profiling of microbiota in the human gut Glucocorticoid-enhanced extinction-based exposure therapy in Irritable Bowel Syndrome Gluten reaction in children and young adults with cerebral palsy (CP) Gut-Brain axis in children and young adults with cerebral palsy (CP) Health Consequences of Environmental Exposures in Early Life Identifying mechanisms for development of novel therapeutic strategies to treat age-associated constipation and diarrhoea (FODI) Integrative bioinformatics: combining clinical, physiological, brain imaging and molecular profiles Intervention with Cognitive Behavioral Therapy for subjects with IBS and its effects on visceral perception, abdominal complaints, psychological functioning and gut microbiota Microbe-host interactions in post-infectious irritable bowel syndrome (PI-IBS) Microbiota Microbiota cross-talk in host cell interactions Probiotic Lactobacillus modulation of cellular immune responses Psycho(bio)logical effects of a probiotic mixture - an fMRI study The effect of probiotic supplementation on antibody response against SARS-CoV-2 in healthy adults The specific antibody response in children with cerebral palsy(CP). To evaluate anti-oxidative and anti-inflammatory effects of butyrate on the transport of large neutral amino acids such as tryptophan, a precursor of the neurotransmitter serotonin, in in vitro models Transglutaminases in children with cerebral palsy (CP)
