Genetic variants in juvenile granulosa cell tumors in Swedish children

The most common form of granulosa cell tumors in children is the juvenile type. In our systematic review described above, we found associations between juvenile granulosa cell tumors and unusual or rare comorbidities. We plan to perform whole-exome sequencing of stored tumor samples in clinical sample collections around Sweden. The aim is to increase our knowledge of the pathogenesis of this rare tumor in children, which hopefully also can increase our knowledge of the pathogenesis of the rare associated conditions.