Johan Bohr

Artiklar i tidskrifter

• Lushnikova, A. , Sjöberg, K. , Münch, A. , Lange, A. , Bohr, J. , Hultgren, O. & Hultgren Hörnquist, E. (2021). Altered levels of immune checkpoint molecules in colon biopsies and sera from microscopic colitis and ulcerative colitis patients compared to controls. Journal of Immunology, 206 (Suppl.).
• Münch, A. , Mihaly, E. , Nagy, F. , Madisch, A. , Kupcinskas, J. , Miehlke, S. , Bohr, J. , Bouma, G. & et al. (2021). Budesonide as induction therapy for incomplete microscopic colitis: A randomised, placebo-controlled multicentre trial. United European Gastroenterology journal, 9 (7), 837-847.
• Verhaegh, B. P. M. , Münch, A. , Guagnozzi, D. , Wildt, S. , Cebula, W. , Diac, A. R. , Fernández-Bañares, F. , Al-Khalaf, M. A. R. & et al. (2021). Course of disease in patients with microscopic colitis: a European prospective incident cohort study. Journal of Crohn's & Colitis, 15 (7), 1174-1183.
• Lushnikova, A. , Bohr, J. , Wickbom, A. , Münch, A. , Sjöberg, K. , Hultgren, O. , Wirén, A. & Hultgren Hörnquist, E. (2021). Patients With Microscopic Colitis Have Altered Levels of Inhibitory and Stimulatory Biomarkers in Colon Biopsies and Sera Compared to Non-inflamed Controls. Frontiers in Medicine, 8.
• Holster, S. , Rode, J. , Bohr, J. , Kumawat, A. K. , Veress, G. , Hultgren Hörnquist, E. , Brummer, R. J. & König, J. (2020). Faecal microbiota transfer in patients with microscopic colitis: a pilot study in collagenous colitis. Scandinavian Journal of Gastroenterology, 55 (12), 1454-1466.
• Larsson, J. K. , Dabos, K. J. , Höglund, P. , Bohr, J. , Münch, A. , Giannakou, A. , Nemeth, A. , Wurm-Johansson, G. & et al. (2019). Cancer Risk in Collagenous Colitis. Journal of Clinical Medicine, 8 (11).
• Carstens, A. , Dicksved, J. , Nelson, R. , Lindqvist, C. M. , Andreasson, A. , Bohr, J. , Tysk, C. , Talley, N. J. & et al. (2019). The Gut Microbiota in Collagenous Colitis Shares Characteristics With Inflammatory Bowel Disease-Associated Dysbiosis. Clinical and Translational Gastroenterology, 10 (7).
• Gunaltay, S. , Rademacher, L. , Hultgren Hörnquist, E. & Bohr, J. (2017). Clinical and immunologic effects of faecal microbiota transplantation in a patient with collagenous colitis. World Journal of Gastroenterology, 23 (7), 1319-1324.
• Wickbom, A. , Nyhlin, N. , Montgomery, S. M. , Bohr, J. & Tysk, C. (2017). Family history, comorbidity, smoking and other risk factors in microscopic colitis: a case-control study. European Journal of Gastroenterology and Hepathology, 29 (5), 587-594.
• Gunaltay, S. , Repsilber, D. , Helenius, G. , Nyhlin, N. , Bohr, J. , Hultgren, O. & Hultgren Hörnquist, E. (2017). Oligoclonal T-cell Receptor Repertoire in Colonic Biopsies of Patients with Microscopic Colitis and Ulcerative Colitis. Inflammatory Bowel Diseases, 23 (6), 932-945.
• Amcoff, K. , Joossens, M. , Pierik, M. J. , Jonkers, D. , Bohr, J. , Joossens, S. , Romberg-Camps, M. , Nyhlin, N. & et al. (2016). Concordance in Anti-OmpC and Anti-I2 Indicate the Influence of Genetic Predisposition: Results of a European Study of Twins with Crohn's Disease. Journal of Crohn's & Colitis, 10 (6), 695-702.
• Munch, A. , Bohr, J. , Miehlke, S. , Benoni, C. , Olesen, M. , Öst, Å. , Strandberg, L. , Hellström, P. M. & et al. (2016). Low-dose budesonide for maintenance of clinical remission in collagenous colitis: a randomised, placebo-controlled, 12-month trial. Gut, 65 (1), 47-56.
• Münch, A. , Tysk, C. , Bohr, J. , Madisch, A. , Bonderup, O. K. , Mohrbacher, R. , Mueller, R. , Greinwald, R. & et al. (2016). Smoking Status Influences Clinical Outcome in Collagenous Colitis. Journal of Crohn's & Colitis, 10 (4), 449-454.
• Gunaltay, S. , Kumawat, A. K. , Nyhlin, N. , Bohr, J. , Tysk, C. , Hultgren, O. & Hultgren-Hörnquist, E. (2015). Enhanced levels of chemokines and their receptors in the colon of microscopic colitis patients indicate mixed immune cell recruitment. Mediators of Inflammation.
• Kumawat, A. K. , Nyhlin, N. , Wickbom, A. , Tysk, C. , Bohr, J. , Hultgren, O. & Hultgren-Hörnquist, E. (2014). An In Vitro Model to Evaluate the Impact of the Soluble Factors from the Colonic Mucosa of Collagenous Colitis Patients on T Cells: Enhanced Production of IL-17A and IL-10 from Peripheral CD4(+) T Cells. Mediators of Inflammation.
• Günaltay, S. , Nyhlin, N. , Kumawat, A. K. , Tysk, C. , Bohr, J. , Hultgren, O. & Hultgren-Hörnquist, E. (2014). Differential expression of interleukin-1/Toll-like receptor signaling regulators in microscopic and ulcerative colitis. World Journal of Gastroenterology, 20 (34), 12249-12259.
• Nyhlin, N. , Wickbom, A. , Montgomery, S. M. , Tysk, C. & Bohr, J. (2014). Letter: persisting clinical symptoms in microscopic colitis in remission - authors' reply. Alimentary Pharmacology and Therapeutics, 40 (1), 118-118.
• Nyhlin, N. , Wickbom, A. , Montgomery, S. M. , Tysk, C. & Bohr, J. (2014). Long-term prognosis of clinical symptoms and health-related quality of life in microscopic colitis: a case-control study. Alimentary Pharmacology and Therapeutics, 39 (9), 963-972.
• Kumawat, A. , Tysk, C. , Bohr, J. , Hultgren, O. & Hultgren-Hörnquist, E. (2013). An in vitro model for analysis of the impact of the colonic milieu in collagenous colitis patients on peripheral T lymphocyte activation and differentiation. Immunology, 140, 168-168.
• Vigren, L. , Tysk, C. , Ström, M. , Kilander, A. F. , Hjortswang, H. , Bohr, J. , Benoni, C. , Larson, L. & et al. (2013). Celiac disease and other autoimmune diseases in patients with collagenous colitis. Scandinavian Journal of Gastroenterology, 48 (8), 944-950.
• Gunaltay, S. , Nyhlin, N. , Kumawat, A. , Tysk, C. , Bohr, J. , Hultgren, O. & Hultgren-Hörnquist, E. (2013). IL-1/TLR signaling inhibitors in microscopic and ulcerative colitis: Immunopathogenic markers of active disease and remission. Immunology, 140, 167-167.
• Göranzon, C. , Kumawat, A. K. , Hultgren-Hörnqvist, E. , Tysk, C. , Eriksson, S. , Bohr, J. & Nyhlin, N. (2013). Immunohistochemical characterization of lymphocytes in microscopic colitis. Journal of Crohn's and Colitis, 7 (10), e434-e442.
• Gunaltay, S. , Nyhlin, N. , Kumawat, A. , Bohr, J. , Tysk, C. , Hultgren, O. & Hultgren-Hörnquist, E. (2013). Increased expression of T cell recruiting chemokines in the colonic mucosa of microscopic colitis patients. Immunology, 140, 135-135.
• Münch, A. , Bohr, J. , Vigren, L. , Tysk, C. & Ström, M. (2013). Lack of effect of methotrexate in budesonide-refractory collagenous colitis. Clinical and Experimental Gastroenterology, 6, 149-52.
• Kumawat, A. K. , Strid, H. , Tysk, C. , Bohr, J. & Hultgren-Hörnquist, E. (2013). Microscopic colitis patients demonstrate a mixed Th17/Tc17 and Th1/Tc1 mucosal cytokine profile. Molecular Immunology, 55 (3-4), 355-364.
• Kumawat, A. K. , Strid, H. , Elgbratt, K. , Tysk, C. , Bohr, J. & Hultgren Hörnquist, E. (2013). Microscopic colitis patients have increased frequencies of Ki67⁺proliferating and CD45RO⁺ active/memory CD8⁺ and CD4⁺8⁺ mucosal T cells. Journal of Crohn's & Colitis, 7 (9), 694-705.
• Fransén, K. , Franzén, P. , Magnuson, A. , Elmabsout, A. , Nyhlin, N. , Wickbom, A. , Curman, B. , Törkvist, L. & et al. (2013). Polymorphism in the retinoic acid metabolizing enzyme CYP26B1 and the development of Crohn's disease. PLOS ONE, 8 (8), e72739.
• Kumawat, A. K. , Elgbratt, K. , Tysk, C. , Bohr, J. & Hultgren-Hörnquist, E. (2013). Reduced T cell receptor excision circle levels in the colonic mucosa of microscopic colitis patients indicate local proliferation rather than homing of peripheral lymphocytes to the inflamed mucosa. BioMed Research International.
• Wickbom, A. , Bohr, J. , Eriksson, S. , Udumyan, R. , Nyhlin, N. & Tysk, C. (2013). Stable Incidence of Collagenous Colitis and Lymphocytic Colitis in Orebro, Sweden, 1999-2008: A Continuous Epidemiologic Study. Inflammatory Bowel Diseases, 19 (11), 2387-2393.
• Zhulina, Y. , Hahn-Strömberg, V. , Shamikh, A. , Peterson, C. G. B. , Gustavsson, A. , Nyhlin, N. , Wickbom, A. , Bohr, J. & et al. (2013). Subclinical Inflammation with Increased Neutrophil Activity in Healthy Twin Siblings Reflect Environmental Influence in the Pathogenesis of Inflammatory Bowel Disease. Inflammatory Bowel Diseases, 19 (8), 1725-1731.
• Zhulina, Y. , Hahn Strömberg, V. , Shamikh, A. , Gustavsson, A. , Bohr, J. , Nyhlin, N. , Wickbom, A. , Bodin, L. & et al. (2012). Aktiverad NFkB i colonbiopsier hos tvillingar med inflammatorisk tarmsjukdom. Gastrokuriren, 17 (37), PO-27-PO-27.
• Amcoff, K. , Joossens, M. , Pierik, M. J. , Jonkers, D. , Bohr, J. , Joossens, S. , Romberg-Camp, M. , Nyhlin, N. & et al. (2012). Arvets inverkan på serologiska markörer hos tvillingar med IBD. Gastrokuriren, 17 (26), MP-06-MP-06.
• Edling, L. , Rathsman, S. , Eriksson, S. & Bohr, J. (2012). Celiac disease and giardiasis: a case report. European Journal of Gastroenterology and Hepathology, 24 (8), 984-987.
• Amcoff, K. , Joossens, M. , Pierik, M. J. , Jonkers, D. , Bohr, J. , Joossens, S. , Romberg-Camps, M. , Nyhlin, N. & et al. (2012). Influence of genetics in the expression of serological markers in twins with IBD. Gastroenterology, 142 (5), S881-S881.
• Münch, A. , Bohr, J. , Vigren, L. , Tysk, C. & Ström, M. (2012). Metotrexat vid budesonid refraktär kollagen kolit. Gastrokuriren, 17 (34), PO-15-PO-15.
• Münch, A. , Aust, D. , Bohr, J. , Bonderup, O. , Bañares, F. F. , Hjortswang, H. , Madisch, A. , Munck, L. K. & et al. (2012). Microscopic colitis: current status, present and future challenges statements of the European microscopic colitis group. Journal of Crohn's & Colitis, 6 (9), 932-945.
• Strid, H. , Kumawat, A. K. , Tysk, C. , Hultgren Hörnquist, E. & Bohr, J. (2011). Altered gene expression of IL-6 and rennin in colonic biopsies from collagenous colitis and ulcerative colitis compared to healthy controls. Gut, 60 (Suppl. 3).
• Kumawat, A. K. , Strid, H. , Elgbratt, K. , Nyhlin, N. , Tysk, C. , Bohr, J. & Hultgren Hörnquist, E. (2011). Collagenous colitis patients demonstrate a Th1/CTL-associated gene expression profile with increased frequencies of Ki67⁺ proliferating and CD45RO⁺ activated/memory CD8⁺ and CD4⁺8⁺ mucosal T cells. Gut, 60 (Suppl. 3), A318.
• Zhulina, Y. , Carlson, M. , Peterson, C. , Gustavsson, A. , Bohr, J. , Bodin, L. , Tysk, C. & Halfvarson, J. (2011). Fekalt calprotectin hos tvillingar med inflammatorisk tarmsjukdom. Gastrokuriren, 16 (29), PO-09-PO-09.
• Hjortswang, H. , Tysk, C. , Bohr, J. , Benoni, C. , Vigren, L. , Kilander, A. , Larsson, L. , Taha, Y. & et al. (2011). Health-related quality of life is impaired in active collagenous colitis. Digestive and Liver Disease, 43 (2), 102-109.
• Göranzon, C. , Hultgren Hörnquist, E. , Kumawat, A. K. , Halfvarson, J. , Tysk, C. , Eriksson, J. , Bohr, J. & Nyhlin, N. (2011). Immunohistokemisk karakterisering av lymfocyter vid microscopisk kolit. Gastrokuriren, 16 (29), PO16-PO16.
• Kumawat, A. , Elgbratt, K. , Bohr, J. , Tysk, C. & Hultgren Hörnquist, E. (2011). Increased frequencies of Ki67⁺ proliferating and CD45RO⁺ memory CD8⁺ and CD4⁺8⁺ T lymphocytes in the intestinal mucosa of collagenous colitis patients. Scandinavian Journal of Immunology, 73 (4), 374-374.
• Zhulina, Y. , Lindberg, E. , Sjöberg, M. , Nyhlin, N. , Wickbom, A. , Eriksson, C. , Johansson, I. , van Nieuwenhoven, M. A. & et al. (2011). Inflammatorisk tarmsjukdom i Örebro 2010: en epidemiologisk uppdatering. Gastrokuriren, 16 (29), PO-10-PO-10.
• Vigren, L. , Sjöberg, K. , Benoni, C. , Tysk, C. , Bohr, J. , Kilander, A. , Larsson, L. , Ström, M. & et al. (2011). Is smoking a risk factor for collagenous colitis?. Scandinavian Journal of Gastroenterology, 46 (11), 1334-1339.
• Münch, A. , Bohr, J. , Vigren, L. , Tysk, C. & Ström, M. (2011). Methotrexate is not effective in budesonide-refractory collagenous colitis. Gut, 60 (Suppl 3), A406-A406.
• Zhulina, Y. , Hahn Strömberg, V. , Shamikh, A. , Gustavsson, A. , Bohr, J. , Nyhlin, N. , Wickbom, A. , Bodin, L. & et al. (2011). NFkB is activated in colonic mucosa of healthy co-twins to twins with inflammatory bowel disease. Gut, 60 (Suppl 3), A290-A290.
• Vigren, L. , Sjöberg, K. , Benoni, C. , Tysk, C. , Bohr, J. , Kilander, A. , Larsson, L. , Ström, M. & et al. (2011). Rökning och kollagen kolit. Gastrokuriren, 16 (29), PO-17-PO-17.
• Vigren, L. , Sjöberg, K. , Benoni, C. , Tysk, C. , Bohr, J. , Kilander, A. , Larsson, L. , Ström, M. & et al. (2010). Smoking habits in patients with collagenous colitis. Gut, 59 (suppl 3), A182-A182.
• Hjortswang, H. , Tysk, C. , Bohr, J. , Benoni, C. , Kilander, A. , Larsson, L. , Vigren, L. & Ström, M. (2009). Defining clinical criteria for clinical remission and disease activity in collagenous colitis. Inflammatory Bowel Diseases, 15 (12), 1875-1881.
• Zhulina, Y. , Carlson, M. , Peterson, C. G. , Tysk, C. , Gustavsson, A. , Bohr, J. , Bodin, L. & Halfvarson, J. (2009). Subclinical inflammation due to environmental exposure in health co-twins to twins with inflammatory bowel disease. Gastroenterology, 136 (5), A20-A20.
• Nyhlin, N. , Bohr, J. , Montgomery, S. M. , Brummer, R. , Wickbom, A. & Tysk, C. (2008). Abdominal pain is common in microscopic colitis despite remission: a long-term follow-up of 203 patients. Gut, 57 (suppl I).
• Tysk, C. , Bohr, J. , Nyhlin, N. , Wickbom, A. & Eriksson, S. (2008). Diagnosis and management of microscopic colitis. World Journal of Gastroenterology, 14 (48), 7280-7288.
• Bohr, J. , Nyhlin, N. , Eriksson, S. & Tysk, C. (2008). Mikroskopisk kolit hos äkta makar. Gastrokuriren, 13 (30), PO-09.
• Nyhlin, N. , Bergman, J. , Bohr, J. , Gustavsson, A. , Halfvarson, J. , Salén, E. , Sandberg Gertzén, H. & Tysk, C. (2008). Plasmaferes vid svår läkemedelsutlöst kolestas. Gastrokuriren, 13 (33), PO-16.

Artiklar, forskningsöversikter

• Miehlke, S. , Guagnozzi, D. , Zabana, Y. , Tontini, G. E. , Fiehn, A. K. , Wildt, S. , Bohr, J. , Bonderup, O. & et al. (2021). European guidelines on microscopic colitis: United European Gastroenterology (UEG) and European Microscopic Colitis Group (EMCG) statements and recommendations. United European Gastroenterology journal, 9 (1), 13-37.
• Bohr, J. , Wickbom, A. , Hegedus, A. , Nyhlin, N. , Hultgren-Hörnquist, E. & Tysk, C. (2014). Diagnosis and management of microscopic colitis: Current perspectives. Clinical and Experimental Gastroenterology, 7, 273-284.
• Tysk, C. , Wickbom, A. , Nyhlin, N. , Eriksson, S. & Bohr, J. (2011). Recent advances in diagnosis and treatment of microscopic colitis. Annals of Gastroenterology, 24 (4), 253-262.
• Nyhlin, N. , Bohr, J. , Eriksson, S. & Tysk, C. (2008). Microscopic colitis: a common and an easily overlooked cause of chronic diarrhoea. European journal of internal medicine, 19 (3), 181-186.

Kapitel i böcker, del av antologier

• Bohr, J. , Löfberg, R. & Tysk, C. (2010). Microscopic colitis: collagenous and lymphocytic colitis. I: John McDonald, Andrew Burroughs, Brian Feagan, M. Brian Fennerty, Evidence-based gastroenterology and hepatology (ss. 257-266). . Wiley-Blackwell.
• Bohr, J. (2008). Mikroskopisk kolit. I: Nyhlin, Henry, Medicinska mag- och tarmsjukdomar (ss. 351-357). Lund: Studentlitteratur.

Konferensbidrag

• Strid, H. , Kumawat, A. , Tysk, C. , Hultgren Hörnquist, E. & Bohr, J. (2012). Genuttrycket för Renin och IL-6 i kolonmucosan är förändrad vid kollagen kolit.  Konferensbidrag vid Svenska Gastrodagarna, Malmö, 8-11 Maj, 2012.
• Kumawat, A. K. , Strid, H. , Tysk, C. , Bohr, J. & Hultgren-Hörnquist, E. (2012). Patienter med mikroskopisk kolit har blandad Th1/Th17 samt CTL-associerad cytokinprofil.  Konferensbidrag vid Svenska Gastrodagarna, Malmö, 8-11 Maj, 2012.
• Kumawat, A. K. , Strid, H. , Elgbratt, K. , Nyhlin, N. , Tysk, C. , Bohr, J. & Hultgren Hörnquist, E. (2011). Collagenous colitis patients demonstrate a Th1/CTL-associated gene expression profile with increased frequencies of Ki67⁺ proliferating and CD45RO⁺ activated/ memory CD8⁺ and CD4⁺8⁺ mucosal T cells.  Konferensbidrag vid International Congress of Mucosal Immunology, Paris, July 5-9, 2011.
• Göranzon, C. , Hultgren Hörnquist, E. , Kumawat, A. K. , Halfvarson, J. , Tysk, C. , Eriksson, S. , Bohr, J. & Nyhlin, N. (2010). Immunohistochemical characterization of lymphocytes in microscopic colitis.  Konferensbidrag vid 18th United European Gastroenterology Week, Barcelona, Oct, 2010.

Manuskript

• Kumawat, A. K. , Tysk, C. , Bohr, J. , Hultgren, O. & Hultgren-Hörnquist, E. An in vitro model for analysis of the impact of the colonic milieu in collagenous colitis patients on peripheral T lymphocyte activation and differentiation.
• Holster, S. , Rode, J. , Bohr, J. , Kumawat, A. K. , Hultgren Hörnquist, E. , Brummer, R. J. & König, J. Faecal microbiota transfer in patients with microscopic colitis : A proof-of-concept study in collagenous colitis.
• Wickbom, A. , Bohr, J. , Nyhlin, N. , Eriksson, A. , Lapidus, A. , Münch, A. , Ung, K. , Vigren, L. & et al. Microscopic colitis in patients with ulcerative colitis or Crohn’s disease : a retrospective observational study and review of the literature.
• Günaltay, S. , Repsilber, D. , Helenius, G. , Nyhlin, N. , Bohr, J. & Hultgren-Hörnquist, E. Oligoclonal T cell receptor repertoire in colonic biopsies of microscopic and ulcerative colitis patients.
• Kumawat, A. K. , Elgbratt, K. , Tysk, C. , Bohr, J. & Hultgren-Hörnquist, E. Reduced T cell receptor excision circle (TREC) levels in the colonic mucosa of microscopic colitis patients indicate local proliferation rather than homing of peripheral lymphocytes to the inflamed mucosa.