Aidan McGlinchey
Befattning: Forskare Organisation: Institutionen för medicinska vetenskaperE-post: aidan.mcglinchey@oru.se
Telefon: 019 302112
Rum: X2217
Forskningsämne
Forskningsprojekt
Pågående projekt
- LITMUS
- Role of environmental exposure in the initiation and progression of non-alcoholic fatty liver disease and insulin resistance
- Sen debut av inflammatorisk tarmsjukdom
Avslutade projekt
Forskargrupper
Publikationer
Artiklar i tidskrifter |
Artiklar, forskningsöversikter |
Konferensbidrag |
Artiklar i tidskrifter
- Sen, P. , Qadri, S. , Luukkonen, P. K. , Ragnarsdottir, O. , McGlinchey, A. J. , Jäntti, S. , Juuti, A. , Arola, J. & et al. (2022). Exposure to environmental contaminants is associated with altered hepatic lipid metabolism in non-alcoholic fatty liver disease. Journal of Hepatology, 76 (2), 283-293.
- McGlinchey, A. J. , Govaere, O. , Geng, D. , Ratziu, V. , Allison, M. , Bousier, J. , Petta, S. , de Oliviera, C. & et al. (2022). Metabolic signatures across the full spectrum of non-alcoholic fatty liver disease. JHEP reports : innovation in hepatology, 4 (5).
- Sen, P. , Govaere, O. , Sinioja, T. , McGlinchey, A. J. , Geng, D. , Ratziu, V. , Bugianesi, E. , Schattenberg, J. M. & et al. (2022). Quantitative modeling of human liver reveals dysregulation of glycosphingolipid pathways in nonalcoholic fatty liver disease. iScience, 25 (9).
- Fart, F. , Salihovic, S. , McGlinchey, A. J. , Gareau, M. G. , Oresic, M. , Halfvarson, J. , Hyötyläinen, T. & Schoultz, I. (2021). Perfluoroalkyl substances are increased in patients with late-onset ulcerative colitis and induce intestinal barrier defects ex vivo in murine intestinal tissue. Scandinavian Journal of Gastroenterology, 56 (11), 1286-1295.
- Hylén, U. , McGlinchey, A. J. , Oresic, M. , Bejerot, S. , Humble, M. B. , Särndahl, E. , Hyötyläinen, T. & Eklund, D. (2021). Potential Transdiagnostic Lipid Mediators of Inflammatory Activity in Individuals With Serious Mental Illness. Frontiers in Psychiatry, 12.
- McGlinchey, A. J. , Sinioja, T. , Lamichhane, S. , Sen, P. , Bodin, J. , Siljander, H. , Dickens, A. M. , Geng, D. & et al. (2020). Prenatal exposure to perfluoroalkyl substances modulates neonatal serum phospholipids, increasing risk of type 1 diabetes. Environment International, 143.
- Mehmood, A. , Laiho, A. , Venäläinen, M. S. , McGlinchey, A. J. , Wang, N. & Elo, L. L. (2020). Systematic evaluation of differential splicing tools for RNA-seq studies. Briefings in Bioinformatics, 21 (6), 2052-2065.
Artiklar, forskningsöversikter
- Sen, P. , Lamichhane, S. , Mathema, V. B. , McGlinchey, A. J. , Dickens, A. M. , Khoomrung, S. & Oresic, M. (2021). Deep learning meets metabolomics: a methodological perspective. Briefings in Bioinformatics, 22 (2), 1531-1542.
- Alves, M. A. , Lamichhane, S. , Dickens, A. , McGlinchey, A. J. , Ribeiro, H. C. , Sen, P. , Wei, F. , Hyötyläinen, T. & et al. (2021). Systems biology approaches to study lipidomes in health and disease. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1866 (2).
- Oresic, M. , McGlinchey, A. J. , Wheelock, C. E. & Hyötyläinen, T. (2020). Metabolic Signatures of the Exposome-Quantifying the Impact of Exposure to Environmental Chemicals on Human Health. Metabolites, 10 (11).
Konferensbidrag
- Sen, P. , Govaere, O. , Sinioja, T. , McGlinchey, A. J. , Geng, D. , Ratziu, V. , Bugianesi, E. , Schattenberg, J. & et al. (2021). Genome-scale metabolic modeling of human hepatocytes reveals dysregulation of glycosphingolipid pathways in progressive non-alcoholic fatty liver disease. I: Journal of Hepatology. Konferensbidrag vid The International Liver Congress, (Digital congress), June 23–26, 2021. (ss. S256-S256). Elsevier.
- McGlinchey, A. J. , Geng, D. , Govaere, O. , Ratziu, V. , Bugianesi, E. , Schattenberg, J. M. , Daley, A. , Hyötyläinen, T. & et al. (2021). The Metabolomics of Non-Alcoholic Fatty Liver Disease: Of Networks and Biomarkers. I: Journal of Hepatology. Konferensbidrag vid The International Liver Congress, (Digital congress), June 23–26, 2021. (ss. S579-S580). Elsevier.
- Fart, F. , Salihovic, S. , McGlinchey, A. J. , Oresic, M. , Halfvarson, J. , Hyötyläinen, T. & Schoultz, I. (2020). Per- and polyfluoroalkyl substances (PFAS) are significantly increased in patients with late-onset of ulcerative colitis. I: Journal of Crohn's & Colitis. Oxford University Press.