Henrik Larsson
Tjänstetitel: Professor Organisation: Institutionen för medicinska vetenskaper
E-post:
Telefon: 019 303681
Rum: C2215
Forskningsämne
Om Henrik Larsson
Henrik Larsson is Professor of epidemiology. The overall objective of his research team’s work on ADHD is to understand how genes and environments influence ADHD across the life span, to map developmental consequences of ADHD and to identify the benefits and risks associated with ADHD treatment interventions. Henrik Larsson’s team use large ADHD cohorts identified from national health registers, the Swedish twin register and clinical cohorts. These datasets contain valid diagnoses of ADHD, prospective measures of environmental risks, high throughput genotyping, longitudinal information on prescribed ADHD medications and assessments of serious medical (psychiatric and somatic problems) and functional (social, educational and occupational) outcomes. Henrik is a faculty member of IMPACT, ECNP, EUNETHYDIS, and the Behavioral Genetic Association.
Forskningsprojekt
- Comorbid Conditions of Attention deficit / hyperactive disorders (CoCA)
- Effects of Nutrition and Lifestyle on Impulsive, Compulsive, and Externalizing behaviours (Eat2beNICE)
- Long-term consequences of Attention-deficit/hyperactivity disorder (ADHD) in adults
- PETSS - Preschool TwinS in Sweden
- Population-based studies of Attention-Deficit/Hyperactivity Disorder and Adverse Health Behaviors
- Predicting Psychiatric and Medical Outcomes of Adult Attention Deficit Hyperactivity Disorder (ADHD).
- Risks and benefits of ADHD medication
Forskargrupper
Publikationer
Artiklar i tidskrifter |
Artiklar, forskningsöversikter |
Manuskript |
Artiklar i tidskrifter
Pettersson, E. , Larsson, H. , D'Onofrio, B. , Almqvist, C.
& Lichtenstein, P. (2019). Association of Fetal Growth With General and Specific Mental Health Conditions. JAMA psychiatry.
Taylor, M. J. , Martin, J. , Lu, Y. , Brikell, I. , Lundström, S. , Larsson, H.
& Lichtenstein, P. (2019). Association of Genetic Risk Factors for Psychiatric Disorders and Traits of These Disorders in a Swedish Population Twin Sample. JAMA psychiatry, 76 (3), 280-289.
Brander, G. , Isomura, K. , Chang, Z. , Kuja-Halkola, R. , Almqvist, C. , Larsson, H. , Mataix-Cols, D.
& Fernández de la Cruz, L. (2019). Association of Tourette Syndrome and Chronic Tic Disorder With Metabolic and Cardiovascular Disorders. JAMA Neurology.
Pettersson, E. , Lichtenstein, P. , Larsson, H. , Song, J. , Agrawal, A. , Børglum, A. D. , Bulik, C. M. , Daly, M. J.
& et al.
(2019). Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls (vol 49, pg 351, 2019). Psychological Medicine, 49 (2), 351-351.
Taylor, M. J. , Larsson, H. , Gillberg, C. , Lichtenstein, P.
& Lundström, S. (2019). Investigating the childhood symptom profile of community-based individuals diagnosed with attention-deficit/hyperactivity disorder as adults. Journal of Child Psychology and Psychiatry and Allied Disciplines, 60 (3), 259-266.
Kennedy, B. , Ruoqing, C. , Fang, F. , Valdimarsdottir, U. , Montgomery, S. , Larsson, H.
& Fall, K. (2019). Low stress resilience in late adolescence and risk of smoking, high alcohol consumption and drug use later in life. Journal of Epidemiology and Community Health.
Ginsberg, Y. , D'Onofrio, B. M. , Rickert, M. E. , Class, Q. A. , Rosenqvist, M. A. , Almqvist, C. , Lichtenstein, P.
& Larsson, H. (2019). Maternal infection requiring hospitalization during pregnancy and attention-deficit hyperactivity disorder in offspring: a quasi-experimental family-based study. Journal of Child Psychology and Psychiatry and Allied Disciplines, 60 (2), 160-168.
Brikell, I. , Chen, Q. , Kuja-Halkola, R. , D'Onofrio, B. M. , Wiggs, K. K. , Lichtenstein, P. , Almqvist, C. , Quinn, P. D.
& et al.
(2019). Medication treatment for attention-deficit/hyperactivity disorder and the risk of acute seizures in individuals with epilepsy. Epilepsia, 60 (2), 284-293.
Gong, T. , Lundholm, C. , Rejnö, G. , Bölte, S. , Larsson, H. , D'Onofrio, B. M. , Lichtenstein, P.
& Almqvist, C. (2019). Parental asthma and risk of autism spectrum disorder in offspring: a population and family based case-control study. Clinical and Experimental Allergy.
Haglund, A. , Lysell, H. , Larsson, H. , Lichtenstein, P.
& Runeson, B. (2019). Suicide Immediately After Discharge From Psychiatric Inpatient Care: A Cohort Study of Nearly 2.9 Million Discharges. Journal of Clinical Psychiatry, 80 (2).
Fazel, S. , Wolf, A. , Larsson, H. , Mallett, S.
& Fanshawe, T. R. (2019). The prediction of suicide in severe mental illness: development and validation of a clinical prediction rule (OxMIS). Translational Psychiatry, 9 (1).
Martin, J. , Walters, R. K. , Demontis, D. , Mattheisen, M. , Lee, S. H. , Robinson, E. , Brikell, I. , Ghirardi, L.
& et al.
(2018). A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder. Biological Psychiatry, 83 (12), 1044-1053.
Mataix-Cols, D. , Frans, E. , Pérez-Vigil, A. , Kuja-Halkola, R. , Gromark, C. , Isomura, K. , Fernández de la Cruz, L. , Serlachius, E.
& et al.
(2018). A total-population multigenerational family clustering study of autoimmune diseases in obsessive-compulsive disorder and Tourette's/chronic tic disorders. Molecular Psychiatry, 23 (7), 1652-1658.
Rosenqvist, M. A. , Sjölander, A. , Ystrom, E. , Larsson, H.
& Reichborn-Kjennerud, T. (2018). Adverse family life events during pregnancy and ADHD symptoms in five-year-old offspring. Journal of Child Psychology and Psychiatry and Allied Disciplines.
Rejnö, G. , Lundholm, C. , Larsson, K. , Larsson, H. , Lichtenstein, P. , D'Onofrio, B. M. , Saltvedt, S.
& Almqvist, C. (2018). Adverse Pregnancy Outcomes in Asthmatic Women: A Population-Based Family Design Study. Journal of Allergy and Clinical Immunology: In Practice, 6 (3), 916-922.e6.
MacCabe, J. H. , Sariaslan, A. , Almqvist, C. , Lichtenstein, P. , Larsson, H.
& Kyaga, S. (2018). Artistic creativity and risk for schizophrenia, bipolar disorder and unipolar depression: a Swedish population-based case-control study and sib-pair analysis. British Journal of Psychiatry, 212 (6), 370-376.
Pérez-Vigil, A. , Fernández de la Cruz, L. , Brander, G. , Isomura, K. , Jangmo, A. , Feldman, I. , Hesselmark, E. , Serlachius, E.
& et al.
(2018). Association of Obsessive-Compulsive Disorder With Objective Indicators of Educational Attainment: A Nationwide Register-Based Sibling Control Study. JAMA psychiatry, 75 (1), 47-55.
Pérez-Vigil, A. , Fernández de la Cruz, L. , Brander, G. , Isomura, K. , Jangmo, A. , Kuja-Halkola, R. , Hesselmark, E. , D'Onofrio, B. M.
& et al.
(2018). Association of Tourette Syndrome and Chronic Tic Disorders With Objective Indicators of Educational Attainment: A Population-Based Sibling Comparison Study. JAMA Neurology, 75 (9), 1098-1105.
Baker, J. H. , Brosof, L. C. , Munn-Chernoff, M. A. , Lichtenstein, P. , Larsson, H. , Maes, H. H.
& Kendler, K. S. (2018). Associations Between Alcohol Involvement and Drive for Thinness and Body Dissatisfaction in Adolescent Twins: A Bivariate Twin Study. Alcoholism: Clinical and Experimental Research, 42 (11), 2214-2223.
Chen, Q. , Hartman, C. A. , Kuja-Halkola, R. , Faraone, S. V. , Almqvist, C.
& Larsson, H. (2018). Attention-deficit/hyperactivity disorder and clinically diagnosed obesity in adolescence and young adulthood: a register-based study in Sweden. Psychological Medicine, 1-9.
Wiggs, K. K. , Chang, Z. , Quinn, P. D. , Hur, K. , Gibbons, R. , Dunn, D. , Brikell, I. , Larsson, H.
& et al.
(2018). Attention-deficit/hyperactivity disorder medication and seizures. Neurology, 90 (13), e1104-e1110.
Hedman, A. , Breithaupt, L. , Hübel, C. , Thornton, L. M. , Tillander, A. , Norring, C. , Birgegård, A. , Larsson, H.
& et al.
(2018). Bidirectional relationship between eating disorders and autoimmune diseases. Journal of Child Psychology and Psychiatry and Allied Disciplines.
Chen, Q. , Hartman, C. A. , Haavik, J. , Harro, J. , Klungsøyr, K. , Hegvik, T. , Wanders, R. , Ottosen, C.
& et al.
(2018). Common psychiatric and metabolic comorbidity of adult attention-deficit/hyperactivity disorder: A population-based cross-sectional study. PLoS ONE, 13 (9).
Martin, J. , Tammimies, K. , Karlsson, R. , Lu, Y. , Larsson, H. , Lichtenstein, P.
& Magnusson, P. K. E. (2018). Copy number variation and neuropsychiatric problems in females and males in the general population. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics.
Pettersson, E. , Lahey, B. B. , Larsson, H.
& Lichtenstein, P. (2018). Criterion Validity and Utility of the General Factor of Psychopathology in Childhood: Predictive Associations With Independently Measured Severe Adverse Mental Health Outcomes in Adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 57 (6), 372-383.
Kuja-Halkola, R. , Lind Juto, K. , Skoglund, C. , Rück, C. , Mataix-Cols, D. , Pérez-Vigil, A. , Larsson, J. , Hellner, C.
& et al.
(2018). Do borderline personality disorder and attention-deficit/hyperactivity disorder co-aggregate in families?: A population-based study of 2 million Swedes. Molecular Psychiatry.
Sundelin, H. E. K. , Chang, Z. , Larsson, H. , Lichtenstein, P. , Almqvist, C. , Tomson, T.
& Ludvigsson, J. F. (2018). Epilepsy, antiepileptic drugs, and serious transport accidents: A nationwide cohort study. Neurology, 90 (13), E1111-+.
Taylor, M. J. , Gustafsson, P. , Larsson, H. , Gillberg, C. , Lundström, S.
& Lichstenstein, P. (2018). Examining the Association Between Autistic Traits and Atypical Sensory Reactivity: A Twin Study. Journal of the American Academy of Child and Adolescent Psychiatry, 57 (2), 96-102.
Brikell, I. , Ghirardi, L. , D'Onofrio, B. M. , Dunn, D. W. , Almqvist, C. , Dalsgaard, S. , Kuja-Halkola, R.
& Larsson, H. (2018). Familial Liability to Epilepsy and Attention-Deficit/Hyperactivity Disorder: A Nationwide Cohort Study. Biological Psychiatry, 83 (2), 173-180.
Ghirardi, L. , Pettersson, E. , Taylor, M. J. , Freitag, C. M. , Franke, B. , Asherson, P. , Larsson, H.
& Kuja-Halkola, R. (2018). Genetic and environmental contribution to the overlap between ADHD and ASD trait dimensions in young adults: a twin study. Psychological Medicine, 1-9.
Pettersson, E. , Lichtenstein, P. , Larsson, H. , Song, J. , Agrawal, A. , Børglum, A. D. , Bulik, C. M. , Daly, M. J.
& et al.
(2018). Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls. Psychological Medicine, 1-8.
Andersson, A. , Tuvblad, C. , Kuja-Halkola, R. , Chen, Q.
& Larsson, H. (2018). Genetic overlap between ADHD and externalizing, internalizing and neurodevelopmental disorder symptoms: a systematic review and meta-analysis. Behavior Genetics, 48 (6), 455-456.
Rydell, M. , Lundström, S. , Gillberg, C. , Lichtenstein, P.
& Larsson, H. (2018). Has the attention deficit hyperactivity disorder phenotype become more common in children between 2004 and 2014?: Trends over 10 years from a Swedish general population sample. Journal of Child Psychology and Psychiatry and Allied Disciplines, 59 (8), 863-871.
Baker, J. H. , Johnson, N. K. , Munn-Chernoff, M. A. , Lichtenstein, P. , Larsson, H. , Maes, H. H.
& Kendler, K. S. (2018). Illicit Drug Use, Cigarette Smoking, and Eating Disorder Symptoms: Associations in an Adolescent Twin Sample. Journal of Studies on Alcohol and Drugs, 79 (5), 720-724.
Brew, B. K. , Lundholm, C. , Viktorin, A. , Lichtenstein, P. , Larsson, H.
& Almqvist, C. (2018). Longitudinal depression or anxiety in mothers and offspring asthma: a Swedish population-based study. International Journal of Epidemiology, 47 (1), 166-174.
Munk-Olsen, T. , Liu, X. , Viktorin, A. , Brown, H. K. , Di Florio, A. , D'Onofrio, B. M. , Gomes, T. , Howard, L. M.
& et al.
(2018). Maternal and infant outcomes associated with lithium use in pregnancy: an international collaborative meta-analysis of six cohort studies. Lancet psychiatry, 5 (8), 644-652.
Molero, Y. , Zetterqvist, J. , Binswanger, I. A. , Hellner, C. , Larsson, H.
& Fazel, S. (2018). Medications for Alcohol and Opioid Use Disorders and Risk of Suicidal Behavior, Accidental Overdoses, and Crime. American Journal of Psychiatry, 175 (10), 970-978.
Isomura, K. , Brander, G. , Chang, Z. , Kuja-Halkola, R. , Rück, C. , Hellner, C. , Lichtenstein, P. , Larsson, H.
& et al.
(2018). Metabolic and Cardiovascular Complications in Obsessive-Compulsive Disorder: A Total Population, Sibling Comparison Study With Long-Term Follow-up. Biological Psychiatry, 84 (5), 324-331.
Beckman, K. , Mittendorfer-Rutz, E. , Waern, M. , Larsson, H. , Runeson, B.
& Dahlin, M. (2018). Method of self-harm in adolescents and young adults and risk of subsequent suicide. Journal of Child Psychology and Psychiatry and Allied Disciplines, 59 (5), 948-956.
Cortese, S. , Sun, S. , Zhang, J. , Sharma, E. , Chang, Z. , Kuja-Halkola, R. , Almqvist, C. , Larsson, H.
& et al.
(2018). Need for further analysis to explore the association between ADHD and asthma: Authors' reply. Lancet psychiatry, 5 (12), 963-964.
Butwicka, A. , Sariaslan, A. , Larsson, H. , Halfvarson, J. , Myrelid, P. E. , Olén, O. , Frisen, L. , Lichtenstein, P.
& et al.
(2018). No association between urbanisation, neighbourhood deprivation and IBD: a population-based study of 4 million individuals. Gut.
Class, Q. A. , Rickert, M. E. , Larsson, H. , Öberg, A. S. , Sujan, A. C. , Almqvist, C. , Lichtenstein, P.
& D'Onofrio, B. M. (2018). Outcome-dependent associations between short interpregnancy interval and offspring psychological and educational problems: a population-based quasi-experimental study. International Journal of Epidemiology, 47 (4), 1159-1168.
Schaumberg, K. , Jangmo, A. , Thornton, L. M. , Birgegård, A. , Almqvist, C. , Norring, C. , Larsson, H.
& Bulik, C. M. (2018). Patterns of diagnostic transition in eating disorders: a longitudinal population study in Sweden.. Psychological Medicine, 1-9.
Brander, G. , Rydell, M. , Kuja-Halkola, R. , Fernández de la Cruz, L. , Lichtenstein, P. S. , Serlachius, E. , Rück, C. , Almqvist, C.
& et al.
(2018). Perinatal risk factors in Tourette's and chronic tic disorders: a total population sibling comparison study. Molecular Psychiatry, 23 (5), 1189-1197.
Carulla-Roig, M. , Isomura, K. , Pérez-Vigil, A. , Larsson, H. , Hellner, C. , Mataix-Cols, D.
& Fernández de la Cruz, L. (2018). Pharmacoepidemiology of Tourette and Chronic Tic Disorders in Sweden 2005-2013. Journal of child and adolescent psychopharmacology, 28 (9), 637-645.
Wolf, A. , Fanshawe, T. R. , Sariaslan, A. , Cornish, R. , Larsson, H.
& Fazel, S. (2018). Prediction of violent crime on discharge from secure psychiatric hospitals: A clinical prediction rule (FoVOx). European psychiatry, 47, 88-93.
Mowlem, F. D. , Rosenqvist, M. A. , Martin, J. , Lichtenstein, P. , Asherson, P.
& Larsson, H. (2018). Sex differences in predicting ADHD clinical diagnosis and pharmacological treatment. European Child and Adolescent Psychiatry.
Martin, J. , Taylor, M. J. , Rydell, M. , Riglin, L. , Eyre, O. , Lu, Y. , Lundström, S. , Larsson, H.
& et al.
(2018). Sex-specific manifestation of genetic risk for attention deficit hyperactivity disorder in the general population. Journal of Child Psychology and Psychiatry and Allied Disciplines, 59 (8), 908-916.
Song, J. , Kuja-Halkola, R. , Sjölander, A. , Bergen, S. E. , Larsson, H. , Landén, M.
& Lichtenstein, P. (2018). Specificity in Etiology of Subtypes of Bipolar Disorder: Evidence From a Swedish Population-Based Family Study. Biological Psychiatry, 84 (11), 810-816.
Brikell, I. , Larsson, H. , Lu, Y. , Pettersson, E. , Chen, Q. , Kuja-Halkola, R. , Karlsson, R. , Lahey, B. B.
& et al.
(2018). The contribution of common genetic risk variants for ADHD to a general factor of childhood psychopathology. Molecular Psychiatry.
Brew, B. K. , Lundholm, C. , Gong, T. , Larsson, H.
& Almqvist, C. (2018). The familial aggregation of atopic diseases and depression or anxiety in children. Clinical and Experimental Allergy, 48 (6), 703-711.
Ghirardi, L. , Brikell, I. , Kuja-Halkola, R. , Freitag, C. M. , Franke, B. , Asherson, P. , Lichtenstein, P.
& Larsson, H. (2018). The familial co-aggregation of ASD and ADHD: a register-based cohort study. Molecular Psychiatry, 23 (2), 257-262.
Campbell, I. , Lundstrom, S. , Larsson, H. , Lichtenstein, P.
& Lubke, G. (2018). The relation between the age at diagnosis of problem behaviors related to aggression and distal outcomes in Swedish children. European Child and Adolescent Psychiatry.
Wiggs, K. K. , Rickert, M. E. , Hernandez-Diaz, S. , Bateman, B. T. , Almqvist, C. , Larsson, H. , Lichtenstein, P. , Öberg, A. S.
& et al.
(2017). A Family-Based Study of the Association Between Labor Induction and Offspring Attention-Deficit Hyperactivity Disorder and Low Academic Achievement. Behavior Genetics, 47 (4), 383-393.
Cederlöf, M. , Kuja-Halkola, R. , Larsson, H. , Sjölander, A. , Östberg, P. , Lundström, S. , Kelleher, I.
& Lichtenstein, P. (2017). A longitudinal study of adolescent psychotic experiences and later development of substance use disorder and suicidal behavior. Schizophrenia Research, 181, 13-16.
Quinn, P. D. , Chang, Z. , Hur, K. , Gibbons, R. D. , Lahey, B. B. , Rickert, M. E. , Sjölander, A. , Lichtenstein, P.
& et al.
(2017). ADHD Medication and Substance-Related Problems. American Journal of Psychiatry, 174 (9), 877-885.
Brikell, I. , Ghirardi, L. , Chang, Z. , D'Onofrio, B. M. , Kuja-Halkola, R.
& Larsson, H. (2017). ADHD medications and the risk of epileptic seizures: a pharmacoepidemiological study using nationwide register data. European Neuropsychopharmacology, 27 (Suppl. 4), S1113-S1114.
Quinn, P. D. , Rickert, M. E. , Weibull, C. E. , Johansson, A. L. V. , Lichtenstein, P. , Almqvist, C. , Larsson, H. , Iliadou, A. N.
& et al.
(2017). Association Between Maternal Smoking During Pregnancy and Severe Mental Illness in Offspring. JAMA psychiatry, 74 (6), 589-596.
Lu, Y. , Sjölander, A. , Cederlöf, M. , D'Onofrio, B. M. , Almqvist, C. , Larsson, H.
& Lichtenstein, P. (2017). Association Between Medication Use and Performance on Higher Education Entrance Tests in Individuals With Attention-Deficit/Hyperactivity Disorder. JAMA psychiatry, 74 (8), 815-822.
Chang, Z. , Quinn, P. D. , Hur, K. , Gibbons, R. D. , Sjolander, A. , Larsson, H.
& D'Onofrio, B. M. (2017). Association Between Medication Use for Attention-Deficit/Hyperactivity Disorder and Risk of Motor Vehicle Crashes. JAMA psychiatry, 74 (6), 597-603.
Sujan, A. C. , Rickert, M. E. , Öberg, A. S. , Quinn, P. D. , Hernandez-Diaz, S. , Almqvist, C. , Lichtenstein, P. , Larsson, H.
& et al.
(2017). Associations of Maternal Antidepressant Use During the First Trimester of Pregnancy With Preterm Birth, Small for Gestational Age, Autism Spectrum Disorder, and Attention-Deficit/Hyperactivity Disorder in Offspring. Obstetrical and Gynecological Survey, 72 (9), 523-524.
Sujan, A. C. , Rickert, M. E. , Öberg, S. , Quinn, P. D. , Hernandez-Diaz, S. , Almqvist, C. , Lichtenstein, P. , Larsson, H.
& et al.
(2017). Associations of Maternal Antidepressant Use During the First Trimester of Pregnancy With Preterm Birth, Small for Gestational Age, Autism Spectrum Disorder, and Attention-Deficit/Hyperactivity Disorder in Offspring. Journal of the American Medical Association (JAMA), 317 (15), 1553-1562.
Thornton, L. M. , Watson, H. J. , Jangmo, A. , Welch, E. , Wiklund, C. , von Hausswolff-Juhlin, Y. , Norring, C. , Herman, B. K.
& et al.
(2017). Binge-eating disorder in the Swedish national registers: Somatic comorbidity. International Journal of Eating Disorders, 50 (1), 58-65.
Butwicka, A. , Lichtenstein, P. , Frisén, L. , Almqvist, C. , Larsson, H.
& Ludvigsson, J. F. (2017). Celiac disease is associated with childhood psychiatric disorders: A Population-Based Study. Journal of Pediatrics, 184, 87-93.e1.
Larsson, H. (2017). Commentary: Important design features to consider in observational research on the long-term outcomes of ADHD - reflections on Sibley et al. (2017) and Swanson et al. (2017). Journal of Child Psychology and Psychiatry and Allied Disciplines, 58 (6), 679-681.
Bolhuis, K. , Lubke, G. H. , van der Ende, J. , Bartels, M. , van Beijsterveldt, C. E. M. , Lichtenstein, P. , Larsson, H. , Jaddoe, V. W. V.
& et al.
(2017). Disentangling Heterogeneity of Childhood Disruptive Behavior Problems Into Dimensions and Subgroups. Journal of the American Academy of Child and Adolescent Psychiatry, 56 (8), 678-686.
Chen, Q. , Brikell, I. , Lichtenstein, P. , Serlachius, E. , Kuja-Halkola, R. , Sandin, S.
& Larsson, H. (2017). Familial aggregation of attention-deficit/hyperactivity disorder. Journal of Child Psychology and Psychiatry and Allied Disciplines, 58 (3), 231-239.
Capusan, A. J. , Yao, S. , Kuja-Halkola, R. , Bulik, C. M. , Thornton, L. M. , Bendtsen, P. , Marteinsdottir, I. , Thorsell, A.
& et al.
(2017). Genetic and environmental aspects in the association between attention-deficit hyperactivity disorder symptoms and binge-eating behavior in adults: a twin study. Psychological Medicine, 47 (16), 2866-2878.
Rydell, M. , Taylor, M. J.
& Larsson, H. (2017). Genetic and environmental contributions to the association between ADHD and affective problems in early childhood: A Swedish population-based twin study. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 174 (5), 538-546.
Fazel, S. , Wolf, A. , Larsson, H. , Lichtenstein, P. , Mallett, S.
& Fanshawe, T. R. (2017). Identification of low risk of violent crime in severe mental illness with a clinical prediction tool (Oxford Mental Illness and Violence tool [OxMIV]): a derivation and validation study. Lancet psychiatry, 4 (6), 461-468.
Butwicka, A. , Långström, N. , Larsson, H. , Lundström, S. , Serlachius, E. , Almqvist, C. , Frisén, L.
& Lichtenstein, P. (2017). Increased Risk for Substance Use-Related Problems in Autism Spectrum Disorders: A Population-Based Cohort Study. Journal of autism and developmental disorders, 47 (1), 80-89.
Sariaslan, A. , Larsson, H. , Lichtenstein, P.
& Fazel, S. (2017). Neighborhood Influences on Violent Reoffending Risk in Released Prisoners Diagnosed With Psychotic Disorders. Schizophrenia Bulletin, 43 (5), 1011-1020.
Longinetti, E. , Mariosa, D. , Larsson, H. , Ye, W. , Ingre, C. , Almqvist, C. , Lichtenstein, P. , Piehl, F.
& et al.
(2017). Neurodegenerative and psychiatric diseases among families with amyotrophic lateral sclerosis. Neurology, 89 (6), 578-585.
Javaras, K. N. , Rickert, M. E. , Thornton, L. M. , Peat, C. M. , Baker, J. H. , Birgegård, A. , Norring, C. , Landén, M.
& et al.
(2017). Paternal age at childbirth and eating disorders in offspring. Psychological Medicine, 47 (3), 576-584.
Longinetti, E. , Mariosa, D. , Larsson, H. , Almqvist, C. , Lichtenstein, P. , Ye, W.
& Fang, F. (2017). Physical and cognitive fitness in young adulthood and risk of amyotrophic lateral sclerosis at an early age. European Journal of Neurology, 24 (1), 137-142.
Du Rietz, E. , Kuja-Halkola, R. , Brikell, I. , Jangmo, A. , Sariaslan, A. , Lichtenstein, P. , Kuntsi, J.
& Larsson, H. (2017). Predictive validity of parent- and self-rated ADHD symptoms in adolescence on adverse socioeconomic and health outcomes. European Child and Adolescent Psychiatry, 26 (7), 857-867.
Tuvblad, C. , Fanti, K. A. , Andershed, H. , Colins, O. F.
& Larsson, H. (2017). Psychopathic personality traits in 5 year old twins: the importance of genetic and shared environmental influences. European Child and Adolescent Psychiatry, 26 (4), 469-479.
Colins, O. F. , Fanti, K. , Larsson, H.
& Andershed, H. (2017). Psychopathic Traits in Early Childhood: Further Validation of the Child Problematic Traits Inventory. Assessment (Odessa, Fla.), 24 (5), 602-614.
Cederlöf, M. , Maughan, B. , Larsson, H. , D'Onofrio, B. M.
& Plomin, R. (2017). Reading problems and major mental disorders: co-occurrences and familial overlaps in a Swedish nationwide cohort. Journal of Psychiatric Research, 91, 124-129.
Yao, S. , Kuja-Halkola, R. , Thornton, L. M. , Norring, C. , Almqvist, C. , D'Onofrio, B. M. , Lichtenstein, P. , Långström, N.
& et al.
(2017). Risk of being convicted of theft and other crimes in anorexia nervosa and bulimia nervosa: A prospective cohort study in a Swedish female population. International Journal of Eating Disorders, 50 (9), 1095-1103.
Baker, J. H. , Munn-Chernoff, M. A. , Lichtenstein, P. , Larsson, H. , Maes, H.
& Kendler, K. S. (2017). Shared Familial Risk Between Bulimic Symptoms and Alcohol Involvement During Adolescence. Journal of Abnormal Psychology, 126 (5), 506-518.
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& Lichtenstein, P. (2014). Klinefelter syndrome and risk of psychosis, autism and ADHD. Journal of Psychiatric Research, 48 (1), 128-130.
Chang, Z. , Lichtenstein, P. , D'Onofrio, B. M. , Almqvist, C. , Kuja-Halkola, R. , Sjölander, A.
& Larsson, H. (2014). Maternal age at childbirth and risk for ADHD in offspring: a population-based cohort study. International Journal of Epidemiology, 43 (6), 1815-1824.
Fraser, A. , Almqvist, C. , Larsson, H. , Långström, N.
& Lawlor, D. A. (2014). Maternal diabetes in pregnancy and offspring cognitive ability: sibling study with 723,775 men from 579,857 families. Diabetologia, 57 (1), 102-109.
Chen, Q. , Sjölander, A. , Långström, N. , Rodriguez, A. , Serlachius, E. , D'Onofrio, B. M. , Lichtenstein, P.
& Larsson, H. (2014). Maternal pre-pregnancy body mass index and offspring attention deficit hyperactivity disorder: a population-based cohort study using a sibling-comparison design. International Journal of Epidemiology, 43 (1), 83-90.
Kuja-Halkola, R. , D'Onofrio, B. M. , Larsson, H.
& Lichtenstein, P. (2014). Maternal smoking during pregnancy and adverse outcomes in offspring: genetic and environmental sources of covariance. Behavior Genetics, 44 (5), 456-467.
McCoy, B. M. , Rickert, M. E. , Class, Q. A. , Larsson, H. , Lichtenstein, P.
& D'Onofrio, B. M. (2014). Mediators of the association between parental severe mental illness and offspring neurodevelopmental problems. Annals of Epidemiology, 24 (9), 629-634.e1.
Ljung, T. , Sandin, S. , Långström, N. , Runeson, B. , Lichtenstein, P.
& Larsson, H. (2014). Offspring death and subsequent psychiatric morbidity in bereaved parents: addressing mechanisms in a total population cohort. Psychological Medicine, 44 (9), 1897-1887.
Class, Q. A. , Abel, K. M. , Khashan, A. S. , Rickert, M. E. , Dalman, C. , Larsson, H. , Hultman, C. M. , Långström, N.
& et al.
(2014). Offspring psychopathology following preconception, prenatal and postnatal maternal bereavement stress. Psychological Medicine, 44 (1), 71-84.
D'Onofrio, B. M. , Rickert, M. E. , Frans, E. , Kuja-Halkola, R. , Almqvist, C. , Sjölander, A. , Larsson, H.
& Lichtenstein, P. (2014). Paternal age at childbearing and offspring psychiatric and academic morbidity. JAMA psychiatry, 71 (4), 432-438.
Fazel, S. , Zetterqvist, J. , Larsson, H. , Långström, N.
& Lichtenstein, P. (2014). Psychotropics and risk of violent crime: Authors' reply. The Lancet, 384 (9959), 2025-2026.
Halldner, L. , Tillander, A. , Lundholm, C. , Boman, M. , Långström, N. , Larsson, H.
& Lichtenstein, P. (2014). Relative immaturity and ADHD: findings from nationwide registers, parent- and self-reports. Journal of Child Psychology and Psychiatry and Allied Disciplines, 55 (8), 897-904.
Chang, Z. , Lichtenstein, P. , D'Onofrio, B. M. , Sjölander, A.
& Larsson, H. (2014). Serious transport accidents in adults with attention-deficit/hyperactivity disorder and the effect of medication: a population-based study. JAMA psychiatry, 71 (3), 319-325.
Chang, Z. , Lichtenstein, P. , Halldner, L. , D'Onofrio, B. , Serlachius, E. , Fazel, S. , Långström, N.
& Larsson, H. (2014). Stimulant ADHD medication and risk for substance abuse. Journal of Child Psychology and Psychiatry and Allied Disciplines, 55 (8), 878-885.
Webb, R. T. , Lichtenstein, P. , Larsson, H. , Geddes, J. R.
& Fazel, S. (2014). Suicide, hospital-presenting suicide attempts, and criminality in bipolar disorder: examination of risk for multiple adverse outcomes. Journal of Clinical Psychiatry, 75 (8), e809-e816.
Ronald, A. , Larsson, H. , Anckarsäter, H.
& Lichtenstein, P. (2014). Symptoms of autism and ADHD: a Swedish twin study examining their overlap. Journal of Abnormal Psychology, 123 (2), 440-451.
D'Onofrio, B. M. , Class, Q. A. , Lahey, B. B.
& Larsson, H. (2014). Testing the Developmental Origins of Health and Disease Hypothesis for Psychopathology Using Family-Based Quasi-Experimental Designs. Child Development Perspectives, 8 (3), 151-157.
Polderman, T. J. C. , Hoekstra, R. A. , Posthuma, D.
& Larsson, H. (2014). The co-occurrence of autistic and ADHD dimensions in adults: an etiological study in 17,770 twins. Translational Psychiatry, 4.
Sandin, S. , Lichtenstein, P. , Kuja-Halkola, R. , Larsson, H. , Hultman, C. M.
& Reichenberg, A. (2014). The familial risk of autism. Journal of the American Medical Association (JAMA), 311 (17), 1770-1777.
Larsson, H. , Chang, Z. , D'Onofrio, B. M.
& Lichtenstein, P. (2014). The heritability of clinically diagnosed attention deficit hyperactivity disorder across the lifespan. Psychological Medicine, 44 (10), 2223-2229.
Viktorin, A. , Lichtenstein, P. , Thase, M. E. , Larsson, H. , Lundholm, C. , Magnusson, P. K. E.
& Landén, M. (2014). The risk of switch to mania in patients with bipolar disorder during treatment with an antidepressant alone and in combination with a mood stabilizer. American Journal of Psychiatry, 171 (10), 1067-1073.
Ginsberg, Y. , Långström, N. , Larsson, H.
& Lichtenstein, P. (2013). ADHD and criminality: could treatment benefit prisoners with ADHD who are at higher risk of reoffending?. Expert Review of Neurotherapeutics, 13 (4), 345-348.
Sjölander, A. , Lichtenstein, P. , Larsson, H.
& Pawitan, Y. (2013). Between-within models for survival analysis.. Statistics in Medicine, 32 (18), 3067-3076.
Jernelöv, S. , Lekander, M. , Almqvist, C. , Axelsson, J.
& Larsson, H. (2013). Development of atopic disease and disturbed sleep in childhood and adolescence: a longitudinal population-based study. Clinical and Experimental Allergy, 43 (5), 552-9.
Chang, Z. , Lichtenstein, P. , Asherson, P. J.
& Larsson, H. (2013). Developmental twin study of attention problems: high heritabilities throughout development.. JAMA psychiatry, 70 (3), 311-318.
Merwood, A. , Greven, C. U. , Price, T. S. , Rijsdijk, F. , Kuntsi, J. , McLoughlin, G. , Larsson, H.
& Asherson, P. J. (2013). Different heritabilities but shared etiological influences for parent, teacher and self-ratings of ADHD symptoms: an adolescent twin study. Psychological Medicine, 43 (9), 1973-1984.
Larsson, H. , Asherson, P. , Chang, Z. , Ljung, T. , Friedrichs, B. , Larsson, J.
& Lichtenstein, P. (2013). Genetic and environmental influences on adult attention deficit hyperactivity disorder symptoms: a large Swedish population-based study of twins. Psychological Medicine, 43 (1), 197-207.
Kendler, K. S. , Patrick, C. J. , Larsson, H. , Gardner, C. O.
& Lichtenstein, P. (2013). Genetic and environmental risk factors in males for self-report externalizing traits in mid-adolescence and criminal behavior through young adulthood. Psychological Medicine, 43 (10), 2161-2168.
Merwood, A. , Asherson, P.
& Larsson, H. (2013). Genetic associations between the ADHD symptom dimensions and Cloninger's temperament dimensions in adult twins. European Neuropsychopharmacology, 23 (6), 416-425.
Wichers, M. , Gardner, C. , Maes, H. H. , Lichtenstein, P. , Larsson, H.
& Kendler, K. S. (2013). Genetic innovation and stability in externalizing problem behavior across development: a multi-informant twin study. Behavior Genetics, 43 (3), 191-201.
Lichtenstein, P.
& Larsson, H. (2013). Medication for attention deficit-hyperactivity disorder and criminality. New England Journal of Medicine, 368 (8), 775-776.
Ljung, T. , Lichtenstein, P. , Sandin, S. , D'Onofrio, B. , Runeson, B. , Långström, N.
& Larsson, H. (2013). Parental schizophrenia and increased offspring suicide risk: exploring the causal hypothesis using cousin comparisons. Psychological Medicine, 43 (3), 581-590.
D'Onofrio, B. M. , Class, Q. A. , Rickert, M. E. , Larsson, H. , Långström, N.
& Lichtenstein, P. (2013). Preterm birth and mortality and morbidity: a population-based quasi-experimental study. JAMA psychiatry, 70 (11), 1231-1240.
Larsson, H. , Rydén, E. , Boman, M. , Långström, N. , Lichtenstein, P.
& Landén, M. (2013). Risk of bipolar disorder and schizophrenia in relatives of people with attention-deficit hyperactivity disorder. British Journal of Psychiatry, 203 (2), 103-106.
Walum, H. , Larsson, H. , Westberg, L. , Lichtenstein, P.
& Magnusson, P. K. E. (2013). Sex differences in jealousy: a population-based twin study in Sweden. Twin Research and Human Genetics, 16 (5), 941-946.
Zetterqvist, J. , Asherson, P. , Halldner, L. , Långström, N.
& Larsson, H. (2013). Stimulant and non-stimulant attention deficit/hyperactivity disorder drug use: total population study of trends and discontinuation patterns 2006-2009. Acta Psychiatrica Scandinavica, 128 (1), 70-77.
Magnusson, P. K. E. , Almqvist, C. , Rahman, I. , Ganna, A. , Viktorin, A. , Walum, H. , Halldner, L. , Lundström, S.
& et al.
(2013). The Swedish Twin Registry: establishment of a biobank and other recent developments. Twin Research and Human Genetics, 16 (1), 317-329.
Burt, S. A. , Larsson, H. , Lichtenstein, P.
& Klump, K. L. (2012). Additional evidence against shared environmental contributions to attention-deficit/hyperactivity problems. Behavior Genetics, 42 (5), 711-721.
Lundström, S. , Chang, Z. , Råstam, M. , Gillberg, C. , Larsson, H. , Anckarsäter, H.
& Lichtenstein, P. (2012). Autism spectrum disorders and autistic like traits: similar etiology in the extreme end and the normal variation.. Archives of General Psychiatry, 69 (1), 46-52.
Larsson, H. , Anckarsäter, H. , Råstam, M. , Chang, Z.
& Lichtenstein, P. (2012). Childhood attention-deficit hyperactivity disorder as an extreme of a continuous trait: a quantitative genetic study of 8,500 twin pairs. Journal of Child Psychology and Psychiatry and Allied Disciplines, 53 (1), 73-80.
Friedrichs, B. , Igl, W. , Larsson, H.
& Larsson, J. (2012). Coexisting psychiatric problems and stressful life events in adults with symptoms of ADHD: a large Swedish population-based study of twins. Journal of Attention Disorders, 16 (1), 13-22.
Larsson, H. (2012). Commentary: Psychopathic traits enhance adolescents' influence on others and make them less easily influenced by others?--reflections on Kerr et al. (2012). Journal of Child Psychology and Psychiatry and Allied Disciplines, 53 (8), 836-837.
D'Onofrio, B. M. , Rickert, M. E. , Langström, N. , Donahue, K. L. , Coyne, C. A. , Larsson, H. , Ellingson, J. M. , Van Hulle, C. A.
& et al.
(2012). Familial confounding of the association between maternal smoking during pregnancy and offspring substance use and problems. Archives of General Psychiatry, 69 (11), 1140-1150.
Lichtenstein, P. , Halldner, L. , Zetterqvist, J. , Sjölander, A. , Serlachius, E. , Fazel, S. , Långström, N.
& Larsson, H. (2012). Medication for attention deficit-hyperactivity disorder and criminality. New England Journal of Medicine, 367 (21), 2006-2014.
Chang, Z. , Lichtenstein, P.
& Larsson, H. (2012). The effects of childhood ADHD symptoms on early-onset substance use: a Swedish twin study. Journal of Abnormal Child Psychology, 40 (3), 319-325.
Walum, H. , Lichtenstein, P. , Neiderhiser, J. M. , Reiss, D. , Ganiban, J. M. , Spotts, E. L. , Pedersen, N. L. , Anckarsäter, H.
& et al.
(2012). Variation in the oxytocin receptor gene is associated with pair-bonding and social behavior. Biological Psychiatry, 71 (5), 419-426.
Ronald, A. , Larsson, H. , Anckarsäter, H.
& Lichtenstein, P. (2011). A twin study of autism symptoms in Sweden. Molecular Psychiatry, 16 (10), 1039-1047.
Mogensen, N. , Larsson, H. , Lundholm, C.
& Almqvist, C. (2011). Association between childhood asthma and ADHD symptoms in adolescence: a prospective population-based twin study. Allergy. European Journal of Allergy and Clinical Immunology, 66 (9), 1224-1230.
Larsson, H. , Dilshad, R. , Lichtenstein, P.
& Barker, E. D. (2011). Developmental trajectories of DSM-IV symptoms of attention-deficit/hyperactivity disorder: genetic effects, family risk and associated psychopathology. Journal of Child Psychology and Psychiatry and Allied Disciplines, 52 (9), 954-963.
Edwards, A. C. , Larsson, H. , Lichtenstein, P.
& Kendler, K. S. (2011). Early environmental influences contribute to covariation between internalizing symptoms and alcohol intoxication frequency across adolescence. Addictive Behaviours, 36 (3), 175-182.
Gustafsson, P. A. , Gustafsson, P. E. , Anckarsäter, H. , Lichtenstein, P. , Ljung, T. , Nelson, N.
& Larsson, H. (2011). Heritability of cortisol regulation in children. Twin Research and Human Genetics, 14 (6), 553-561.
Moberg, T. , Lichtenstein, P. , Forsman, M.
& Larsson, H. (2011). Internalizing behavior in adolescent girls affects parental emotional overinvolvement: a cross-lagged twin study. Behavior Genetics, 41 (2), 223-233.
Baker, J. H. , Maes, H. H. , Larsson, H. , Lichtenstein, P.
& Kendler, K. S. (2011). Sex differences and developmental stability in genetic and environmental influences on psychoactive substance consumption from early adolescence to young adulthood. Psychological Medicine, 41 (9), 1907-1916.
Bergman, O. , Westberg, L. , Lichtenstein, P. , Eriksson, E.
& Larsson, H. (2011). Study on the possible association of brain-derived neurotrophic factor polymorphism with the developmental course of symptoms of attention deficit and hyperactivity. International Journal of Neuropsychopharmacology, 14 (10), 1367-1376.
Forsman, M. , Lichtenstein, P. , Andershed, H.
& Larsson, H. (2010). A longitudinal twin study of the direction of effects between psychopathic personality and antisocial behaviour. Journal of Child Psychology and Psychiatry and Allied Disciplines, 51 (1), 39-47.
Sadr Azodi, O. , Andrén-Sandberg, Å.
& Larsson, H. (2009). Genetic and environmental influences on the risk of acute appendicitis in twins. British Journal of Surgery, 96 (11), 1336-1340.
Viding, E. , Larsson, H.
& Jones, A. P. (2008). Quantitative genetic studies of antisocial behaviour. Philosophical Transactions of the Royal Society of London. Biological Sciences, 363 (1503), 2519-2527.
Larsson, H. , Viding, E. , Rijsdijk, F. V.
& Plomin, R. (2008). Relationships between parental negativity and childhood antisocial behavior over time: a bidirectional effects model in a longitudinal genetically informative design. Journal of Abnormal Child Psychology, 36 (5), 633-645.
Larsson, H. , Andershed, H.
& Lichtenstein, P. (2006). A genetic factor explains most of the variation in the psychopathic personality. Journal of Abnormal Psychology, 115 (2), 221-230.
Larsson, H. , Lichtenstein, P.
& Larsson, J. (2006). Genetic contributions to the development of ADHD subtypes from childhood to adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 45 (8), 973-981.
Larsson, J. , Larsson, H.
& Lichtenstein, P. (2004). Genetic and environmental contributions to stability and change of ADHD symptoms between 8 and 13 years of age: a longitudinal twin study. Journal of the American Academy of Child and Adolescent Psychiatry, 43 (10), 1267-1275.
Artiklar, forskningsöversikter
Cortese, S. , Sun, S. , Zhang, J. , Sharma, E. , Chang, Z. , Kuja-Halkola, R. , Almqvist, C. , Larsson, H.
& et al.
(2018). Association between attention deficit hyperactivity disorder and asthma: a systematic review and meta-analysis and a Swedish population-based study. Lancet psychiatry, 5 (9), 717-726.
Faraone, S.
& Larsson, H. (2018). Genetics of attention deficit hyperactivity disorder. Molecular Psychiatry.
Franke, B. , Michelini, G. , Asherson, P. , Banaschewski, T. , Bilbow, A. , Buitelaar, J. K. , Cormand, B. , Faraone, S. V.
& et al.
(2018). Live fast, die young? A review on the developmental trajectories of ADHD across the lifespan. European Neuropsychopharmacology, 28 (10), 1059-1088.
Brander, G. , Pérez-Vigil, A. , Larsson, H.
& Mataix-Cols, D. (2016). Systematic review of environmental risk factors for Obsessive-Compulsive Disorder: A proposed roadmap from association to causation. Neuroscience and Biobehavioral Reviews, 65, 36-62.
D'Onofrio, B. M. , Class, Q. A. , Rickert, M. E. , Sujan, A. C. , Larsson, H. , Kuja-Halkola, R. , Sjölander, A. , Almqvist, C.
& et al.
(2016). Translational Epidemiologic Approaches to Understanding the Consequences of Early-Life Exposures. Behavior Genetics, 46 (3), 315-328.
Brikell, I. , Kuja-Halkola, R.
& Larsson, H. (2015). Heritability of attention-deficit hyperactivity disorder in adults. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 168 (6), 406-413.
Manuskript
Kennedy, B. , Ruoqing, C. , Fang, F. , Valdimarsdottir, U. , Montgomery, S. , Larsson, H.
& Fall, K. Low stress resilience and use of addictive substances.