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Magnus Grenegård

Tjänstetitel: Professor Organisation: Institutionen för medicinska vetenskaper

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Magnus Grenegård

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Publikationer

Artiklar i tidskrifter |  Manuskript | 

Artiklar i tidskrifter

Lunde, N. N. , Gregersen, I. , Ueland, T. , Shetelig, C. , Holm, S. , Kong, X. Y. , Michelsen, A. E. , Otterdal, K. & et al. (2020). Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages. Atherosclerosis, 296, 74-82.
Kardeby, C. , Paramel Varghese, G. , Pournara, D. , Fotopoulou, T. , Sirsjö, A. , Koufaki, M. , Fransén, K. & Grenegård, M. (2019). A novel purine analogue bearing nitrate ester prevents platelet activation by ROCK activity inhibition. European Journal of Pharmacology, 857.
Fälker, K. , Ljungberg, L. , Kardeby, C. , Lindkvist, M. , Sirsjö, A. & Grenegård, M. (2019). Adrenoceptor α2A signalling countervails the taming effects of synchronous cyclic nucleotide-elevation on thrombin-induced human platelet activation and aggregation. Cellular Signalling, 59, 96-109.
Lindkvist, M. , Fernberg, U. , Ljungberg, L. , Fälker, K. , Fernström, M. , Hurtig-Wennlöf, A. & Grenegård, M. (2019). Individual variations in platelet reactivity towards ADP, epinephrine, collagen and nitric oxide, and the association to arterial function in young, healthy adults. Thrombosis Research, 174, 5-12.
Kardeby, C. , Fälker, K. , Haining, E. J. , Criel, M. , Lindkvist, M. , Barroso, R. , Påhlsson, P. , Ljungberg, L. & et al. (2019). Synthetic glycopolymers and natural fucoidans cause human platelet aggregation via PEAR1 and GPIbα. Blood advances, 3 (3), 275-287.
Zegeye, M. M. , Lindkvist, M. , Fälker, K. , Kumawat, A. K. , Paramel Varghese, G. , Grenegård, M. , Sirsjö, A. & Ljungberg, L. U. (2018). Activation of the JAK/STAT3 and PI3K/AKT pathways are crucial for IL-6 trans-signaling-mediated pro-inflammatory response in human vascular endothelial cells. Cell Communication and Signaling, 16 (1).
Tengdelius, M. , Kardeby, C. , Fälker, K. , Griffith, M. , Påhlsson, P. , Konradsson, P. & Grenegård, M. (2017). Fucoidan-Mimetic Glycopolymers as Tools for Studying Molecular and Cellular Responses in Human Blood Platelets. Macromolecular Bioscience, 17 (2).
Donner, L. , Fälker, K. , Gremer, L. , Klinker, S. , Pagani, G. , Ljungberg, L. U. , Lothmann, K. , Rizzi, F. & et al. (2016). Platelets contribute to amyloid-β aggregation in cerebral vessels through integrin αIIbβ3-induced outside-in signaling and clusterin release. Science Signaling, 9 (429).
Sodergren, A. L. , Holm, A. B. S. , Ramström, S. , Lindström, E. G. , Grenegård, M. & Öllinger, K. (2016). Thrombin-induced lysosomal exocytosis in human platelets is dependent on secondary activation by ADP and regulated by endothelial-derived substances. Platelets, 27 (1), 86-92.
Holm, A. B. S. , Grenegård, M. , Ollinger, K. & Lindström, E. G. (2014). Inhibition of 12-lipoxygenase reduces platelet activation and prevents their mitogenic function. Platelets, 25 (2), 111-117.
Tengdelius, M. , Lee, C. , Grenegård, M. , Griffith, M. , Påhlsson, P. & Konradsson, P. (2014). Synthesis and Biological Evaluation of Fucoidan-Mimetic Glycopolymers through Cyanoxyl-Mediated Free-Radical Polymerization. Biomacromolecules, 15 (7), 2359-2368.
Peng, X. , Ramström, S. , Kurz, T. , Grenegård, M. & Segelmark, M. (2014). The neutrophil serine protease PR3 induces shape change of platelets via the Rho/Rho kinase and Ca2+ signaling pathways. Thrombosis Research, 134 (2), 418-425.
Fälker, K. , Klarström-Engström, K. , Bengtsson, T. , Lindahl, T. L. & Grenegård, M. (2014). The Toll-like receptor 2/1 (TLR2/1) complex initiates human platelet activation via the src/Syk/LAT/PLC gamma 2 signalling cascade. Cellular Signalling, 26 (2), 279-286.
Boknäs, N. , Faxälv, L. , Sanchez Cenellas, D. , Wallstedt, M. , Ramström, S. , Grenegård, M. & Lindahl, T. L. (2014). Thrombin-induced platelet activation via PAR4: pivotal role for exosite II. Thrombosis and Haemostasis, 112 (3), 558-565.
Junker, J. P. , Lönnqvist, S. , Rakar, J. , Karlsson, L. K. , Grenegård, M. & Kratz, G. (2013). Differentiation of human dermal fibroblasts towards endothelial cells. Differentiation, 85 (3), 67-77.
Elvers, M. , Grenegård, M. , Khoshjabinzadeh, H. , Münzer, P. , Borst, O. , Tian, H. , Di Paolo, G. , Lang, F. & et al. (2012). A novel role for phospholipase D as an endogenous negative regulator of platelet sensitivity. Cellular Signalling, 24 (9), 1743-52.
Kälvegren, H. , Skoglund, C. , Helldahl, C. , Lerm, M. , Grenegård, M. & Bengtsson, T. (2010). Toll-like receptor 2 stimulation of platelets is mediated by purinergic P2X(1)-dependent Ca2+ mobilisation, cyclooxygenase and purinergic P2Y(1) and P2Y(12) receptor activation. Thrombosis and Haemostasis, 103 (2), 398-407.
Kälvegren, H. , Andersson, J. , Grenegård, M. & Bengtsson, T. (2007). Platelet activation triggered by Chlamydia pneumoniae is antagonized by 12-lipoxygenase inhibitors but not cyclooxygenase inhibitors. European Journal of Pharmacology, 566 (1-3), 20-27.

Manuskript

Kardeby, C. , Paramel Varghese, G. , Pournara, D. , Fotopoulou, T. , Sirsjö, A. , Koufaki, M. , Fransén, K. & Grenegård, M. A novel purine analogue bearing nitrate ester prevents platelet activation by ROCK activity inhibition.
Lindkvist, M. , Ljungberg, L. U. , Fälker, K. , Ramström, S. , Kardeby, C. , Sirsjö, A. & Grenegård, M. IL-6 trans-signalling inhibits micro- and macro-aggregation induced by epinephrine in human platelets.