Gisela Helenius

Artiklar i tidskrifter

• Hermansson, R. S. , Lillsunde-Larsson, G. , Helenius, G. , Karlsson, M. , Kaliff, M. , Olovsson, M. & Lindström, A. K. (2024). History of HPV in HPV-positive elderly women. European journal of obstetrics & gynecology and reproductive biology: X, 22.
• Helenius, G. , Lillsunde-Larsson, G. & Bergengren, L. (2023). Molecular triage of cervical screening samples in women 55-59 years of age: a pilot study. Infectious Agents and Cancer, 18 (1).
• Thurfjell, V. , Micke, P. , Yu, H. , Krupar, R. , Svensson, M. A. , Brunnström, H. , Lamberg, K. , Moens, L. N. J. & et al. (2022). Comparison of ROS1-rearrangement detection methods in a cohort of surgically resected non-small cell lung carcinomas. Translational Lung Cancer Research (TLCR), 11 (12), 2477-2494.
• Bergengren, L. , Ryen, L. , Flodström, C. , Fadl, H. , Udumyen, R. , Karlsson, M. G. & Helenius, G. (2022). Effectiveness and costs of an implemented primary HPV cervical screening programme in Sweden: A population based cohort study. Preventive Medicine Reports, 25.
• Kaliff, M. , Lillsunde-Larsson, G. , Helenius, G. , Karlsson, M. & Bergengren, L. (2022). Full genotyping and FAM19A4/miR124-2 methylation analysis in high-risk human papillomavirus-positive samples from women over 30 years participating in cervical cancer screening in Örebro, Sweden. PLOS ONE, 17 (9).
• Fioretos, T. , Wirta, V. , Cavelier, L. , Berglund, E. , Friedman, M. , Akhras, M. , Botling, J. , Ehrencrona, H. & et al. (2022). Implementing precision medicine in a regionally organized healthcare system in Sweden. Nature Medicine, 28 (10), 1980-1982.
• Berg von Linde, M. , Johansson, K. , Kruse, R. , Helenius, G. , Samano, N. , Friberg, Ö. , Frøbert, A. M. & Fröbert, O. (2021). Expression of Paracrine Effectors in Human Adipose-Derived Mesenchymal Stem Cells Treated With Plasma From Brown Bears (Ursus arctos). Clinical and Translational Science, 14 (1), 317-325.
• Qvick, A. , Stenmark, B. , Carlsson, J. , Isaksson, J. , Karlsson, C. & Helenius, G. (2021). Liquid biopsy as an option for predictive testing and prognosis in patients with lung cancer. Molecular Medicine, 27 (1).
• Edsjö, A. , Palmqvist, R. , Haglund, F. , Helenius, G. , Lindqvist, O. , Fagman, H. & Botling, J. (2021). Molekylär patologi: nyckeln till målinriktad cancerbehandling [Molecular pathology - the key to precision oncology]. Läkartidningen, 118.
• Kaliff, M. , Louise, B. M. , Helenius, G. , Karlsson, M. & Lillsunde-Larsson, G. (2021). Optimization of droplet digital PCR assays for the type specific detection and quantification of five HPV genotypes, also including additional data on viral load of nine different HPV genotypes in cervical carcinomas. Journal of Virological Methods, 294.
• Jans, L. , Zetterström, K. , Bergengren, L. & Helenius, G. (2021). The value of adding a single co-test in HPV primary screening. Preventive Medicine, 149.
• Adolfsson, E. , Helenius, G. , Friberg, Ö. , Samano, N. , Fröbert, O. & Johansson, K. (2020). Bone marrow- and adipose tissue-derived mesenchymal stem cells from donors with coronary artery disease: growth, yield, gene expression and the effect of oxygen concentration. Scandinavian Journal of Clinical and Laboratory Investigation, 80 (4), 318-326.
• Kaliff, M. , Karlsson, M. , Sorbe, B. , Bohr Mordhorst, L. , Helenius, G. & Lillsunde-Larsson, G. (2020). HPV-negative Tumors in a Swedish Cohort of Cervical Cancer. International Journal of Gynecological Pathology, 39 (3), 279-288.
• Bergengren, L. , Karlsson, M. & Helenius, G. (2020). Prevalence of HPV and pathological changes among women 70 years of age, 10 years after exclusion from the Swedish cervical cancer screening program. Cancer Causes and Control, 31 (4), 377-381.
• Bergengren, L. , Lillsunde-Larsson, G. , Helenius, G. & Karlsson, M. G. (2019). HPV-based screening for cervical cancer among women 55-59 years of age. PLOS ONE, 14 (6).
• Östling, H. , Kruse, R. , Helenius, G. & Lodefalk, M. (2019). Placental expression of microRNAs in infants born small for gestational age. Placenta, 81, 46-53.
• Bergengren, L. , Kaliff, M. , Lillsunde-Larsson, G. , Karlsson, M. & Helenius, G. (2018). Comparison between professional sampling and self-sampling for HPV-based cervical cancer screening among postmenopausal women. International Journal of Gynecology & Obstetrics, 142 (3), 359-364.
• Kaliff, M. , Sorbe, B. , Mordhorst, L. B. , Helenius, G. , Karlsson, M. G. & Lillsunde-Larsson, G. (2018). Findings of multiple HPV genotypes in cervical carcinoma are associated with poor cancer-specific survival in a Swedish cohort of cervical cancer primarily treated with radiotherapy. Oncotarget, 9 (27), 18786-18796.
• Lillsunde Larsson, G. , Kaliff, M. , Sorbe, B. , Helenius, G. & Karlsson, M. G. (2018). HPV16 viral characteristics in primary, recurrent and metastatic vulvar carcinoma. Papillomavirus research, 6, 63-69.
• Lillsunde-Larsson, G. & Helenius, G. (2017). Digital droplet PCR (ddPCR) for the detection and quantification of HPV 16, 18, 33 and 45: a short report. Cellular Oncology, 40 (5), 521-527.
• Qvick, A. , Sorbe, B. , Helenius, G. , Karlsson, M. G. & Lillsunde Larsson, G. (2017). Does p53 codon 72 polymorphism have a prognostic value in carcinoma of the vulva and vagina?. Medical Oncology, 34 (3).
• Nyberg, J. , Helenius, G. , Dahlin, C. , Johansson, C. B. & Omar, O. (2017). Molecular Activity and Osseointegration After Single-Dose Irradiation: An In Vivo Study. International Journal of Oral & Maxillofacial Implants, 32 (5), 1033-1038.
• Gunaltay, S. , Repsilber, D. , Helenius, G. , Nyhlin, N. , Bohr, J. , Hultgren, O. & Hultgren Hörnquist, E. (2017). Oligoclonal T-cell Receptor Repertoire in Colonic Biopsies of Patients with Microscopic Colitis and Ulcerative Colitis. Inflammatory Bowel Diseases, 23 (6), 932-945.
• Lillsunde Larsson, G. , Kaliff, M. , Bergengren, L. , Karlsson, M. G. & Helenius, G. (2016). HPV Genotyping from the high risk mRNA Aptima assay: a direct approach using DNA from Aptima sample tubes. Journal of Virological Methods, 235, 80-84.
• Larsson, G. L. , Karlsson, M. G. & Helenius, G. (2016). HPV testing of biobanked liquid-based cytology: a validation study. International Journal of Biological Markers, 31 (2), E218-E223.
• Mattsson, J. S. M. , Brunnström, H. , Jabs, V. , Edlund, K. , Jirström, K. , Mindus, S. , la Fleur, L. , Pontén, F. & et al. (2016). Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer. BMC Cancer, 16 (1).
• Kumakech, E. , Berggren, V. , Wabinga, H. , Lillsunde-Larsson, G. , Helenius, G. , Kaliff, M. , Karlsson, M. , Kirimunda, S. & et al. (2016). Significantly Reduced Genoprevalence of Vaccine-Type HPV-16/18 Infections among Vaccinated Compared to Non-Vaccinated Young Women 5.5 Years after a Bivalent HPV-16/18 Vaccine (Cervarix®) Pilot Project in Uganda. PLOS ONE, 11 (8).
• Lillsunde-Larsson, G. , Carlsson, J. , Karlsson, M. G. & Helenius, G. (2015). Evaluation of HPV Genotyping Assays for Archival Clinical Samples. Journal of Molecular Diagnostics, 17 (3), 293-301.
• Mattsson, J. S. M. , Bergman, B. , Grinberg, M. , Edlund, K. , Marincevic, M. , Jirström, K. , Pontén, F. , Hengstler, J. G. & et al. (2015). Prognostic impact of COX-2 in non-small cell lung cancer: a comprehensive compartment-specific evaluation of tumor and stromal cell expression. Cancer Letters, 356 (2), 837-845.
• Svensson, M. A. , Perner, S. , Ohlson, A. , Day, J. R. , Groskopf, J. , Kirsten, R. , Sollie, T. , Helenius, G. & et al. (2014). A Comparative Study of ERG Status Assessment on DNA, mRNA, and Protein Levels Using Unique Samples from a Swedish Biopsy Cohort. Applied immunohistochemistry & molecular morphology (Print), 22 (2), 136-141.
• Lillsunde-Larsson, G. , Helenius, G. , Sorbe, B. & Karlsson, M. G. (2014). Viral Load, Integration and Methylation of E2BS3 and 4 in Human Papilloma Virus (HPV) 16-Positive Vaginal and Vulvar Carcinomas. PLOS ONE, 9 (11).
• Botling, J. , Edlund, K. , Lohr, M. , Hellwig, B. , Holmberg, L. , Lambe, M. G. , Berglund, A. , Ekman, S. & et al. (2013). Biomarker Discovery in Non-Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation. Clinical Cancer Research, 19 (1), 194-204.
• Carlsson, J. , Helenius, G. , Karlsson, M. G. , Andrén, O. , Klinga-Levan, K. & Olsson, B. (2013). Differences in microRNA expression during tumor development in the transition and peripheral zones of the prostate. BMC Cancer, 13.
• Lillsunde-Larsson, G. , Helenius, G. , Andersson, S. , Sorbe, B. & Karlsson, M. G. (2013). Prognostic impact of human papilloma virus (HPV) genotyping and HPV-16 subtyping in vaginal carcinoma. Gynecologic Oncology, 129 (2), 406-411.
• Lillsunde-Larsson, G. , Helenius, G. , Andersson, S. , Elgh, F. , Sorbe, B. & Karlsson, M. G. (2012). Human Papillomavirus (HPV) and HPV 16-Variant Distribution in Vulvar Squamous Cell Carcinoma in Sweden. International Journal of Gynecological Cancer, 22 (8), 1413-1419.
• Karlsson, C. , Helenius, G. , Fernandes, O. & Karlsson, M. G. (2012). Oestrogen receptor ss in NSCLC: prevalence, proliferative influence, prognostic impact and smoking. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS), 120 (6), 451-458.
• Carlsson, J. , Davidsson, S. , Helenius, G. , Karlsson, M. , Lubovac, Z. , Andrén, O. , Olsson, B. & Klinga-Levan, K. (2011). A miRNA expression signature that separates between normal and malignant prostate tissues. Cancer Cell International (11), 14.
• Kirrander, P. , Kolaric, A. , Helenius, G. , Windahl, T. , Andrén, O. , Stark, J. R. , Lillsunde-Larsson, G. , Elgh, F. & et al. (2011). Human papillomavirus prevalence, distribution and correlation to histopathological parameters in a large Swedish cohort of men with penile carcinoma. BJU International, 108 (3), 355-359.
• Falck, E. , Karlsson, S. , Carlsson, J. , Helenius, G. , Karlsson, M. G. & Klinga-Levan, K. (2010). Loss of glutathione peroxidase 3 expression is correlated with epigenetic mechanisms in endometrial adenocarcinoma. Cancer Cell International, 10.
• Carlsson, J. , Helenius, G. , Karlsson, M. , Lubovac, Z. , Andrén, O. , Olsson, B. & Klinga-Levan, K. (2010). Validation of suitable endogenous control genes for expression studies of miRNA in prostate cancer tissues. Cancer Genetics and Cytogenetics, 202 (2), 71-75.

Konferensbidrag

• Koskela, A. , Qvick, A. , Jakobsen, I. , Lindqvist, C. M. , Farkas, S. A. , Green, A. , Isaksson, H. S. , Holmgren, B. & et al. (2022). Evaluation of Microsatellite instability score from GMS560 DNA panel.  Konferensbidrag vid Cutting-Edge Implementation of Precision Medicine in Europe, Stockholm, Sweden, September 22-23, 2022.
• Salomonsson, A. , Jönsson, M. , Behndig, A. , Bergman, B. , Botling, J. , Brandén, E. , Koyi, H. , Brunnström, H. & et al. (2021). A Nationwide Population-Based Mapping of Mutations and Gene Fusions in Lung Cancer Among Never-Smokers. I:  Journal of Thoracic Oncology. Konferensbidrag vid 2021 World Conference on Lung Cancer - 2021 World Conference on Lung Cancer Worldwide Virtual Event, September 8-14, 2021. (ss. S974-S974). Elsevier.
• Qvick, A. , Wirén, A. , Rönnqvist, M. & Helenius, G. (2019). Circulating miRNA: a biomarker for classification of lung cancer and benign lung disease. I:  Journal of Thoracic Oncology. Konferensbidrag vid World Congress on Lung Cancer 2019, Barcelona, Spain, September 7-10, 2019. (ss. 311-311). Elsevier.
• Kaliff, M. , Bergengren, L. , Helenius, G. , Karlsson, M. & Lillsunde-Larsson, G. (2019). DNA methylation analysis in HPV-positive screening samples from women 30-69 years in the cervical cancer-screening program in Örebro, Sweden: a pilot study. I:  EUROGIN 2019 ABSTRACTS POSTERS. Konferensbidrag vid EUROGIN 2019: International Multidisciplinary HPV Congress, Monaco, December 4-7, 2019.
• Lillsunde-Larsson, G. , Kaliff, M. , Ottestig, E. & Helenius, G. (2019). HPV genotyping of HPV primary screening positive samples in Örebro, Sweden.  Konferensbidrag vid Bioingeniørkongressen 2019, Tromsø, Maj 22-24, 2019.
• Helenius, G. , Lillsunde-Larsson, G. , Bergengren, L. , Kaliff, M. & Karlsson, M. (2019). Preliminary data from a Swedish self-sampling study in postmenopausal women.  Konferensbidrag vid EUROGIN 2019 – International Multidisciplinary HPV Congress, Monte Carlo, Monaco, December 4-7, 2019.
• Helenius, G. , Ottestig, E. , Kaliff, M. , Lillsunde-Larsson, G. , Karlsson, M. & Bergengren, L. (2018). Distribution of HPV-genotypes in a Swedish screening population.  Konferensbidrag vid Eurogin 2018 International multidisciplinary HPV Congress, Lisabon Portugal, December 2-5, 2018.
• Lillsunde-Larsson, G. , Kaliff, M. , Ottestig, E. & Helenius, G. (2018). HPV genotyping of HPV primary screening positive samples in Örebro, Sweden.  Konferensbidrag vid 33rd World congress of Biomedical Laboratory Science (IFBLS), Florens, Italy, 22-26 Sep., 2018.
• Lillsunde-Larsson, G. , Kaliff, M. , Sorbe, B. , Helenius, G. & Karlsson, M. (2018). HPV16 VIRAL CHARACTERISTICS IN PRIMARY AND RECURRENT VULVAR CARCINOMA.  Konferensbidrag vid 32nd International Papillomavirus Conference IPVC 2018, Sydney, Australia, 2-6 October, 2018.
• Lillsunde-Larsson, G. , Kaliff, M. , Hansen, M. & Helenius, G. (2017). Comparison of mRNA and DNA HPV levels in HRHPV-positive primary screening samples using digital droplet PCR.  Konferensbidrag vid EUROGIN 2017, Amsterdam, Netherlands, October 8-11, 2017.
• Östling, H. , Kruse, R. , Helenius, G. & Lodefalk, M. (2017). Infants born small-for-gestational age have different placental expression of microRNAs. I:  Hormone Research in Paediatrics. Konferensbidrag vid 10th International Meeting of Pediatric Endocrinology, Washington D.C., USA, September 14-17, 2017. (ss. 100-101). S. Karger.
• Bergengren, L. , Lillsunde-Larsson, G. , Kaliff, M. , Karlsson, M. & Helenius, G. (2016). Concordance between self sampling and professionally taken cervical hpv test-result from population based cohort study.  Konferensbidrag vid Eurogin, Salzburg, Austria, 2016.
• Mattsson, J. S. M. , Svensson, M. A. , Hallström, B. , Koyi, H. , Branden, E. , Brunnström, H. , Edlund, K. , Ekman, S. & et al. (2015). ALK Rearrangements in Non-Small Cell Lung Cancer: Comprehensive Integration of Genomic, Gene Expression and Protein Analysis. I:  Journal of Thoracic Oncology. Elsevier.

Manuskript

• Svensson, M. A. , Perner, S. , Ohlson, A. , Day, J. R. , Kirsten, R. , Groskopf, J. , Sollie, T. , Helenius, G. & et al. A comparative study of ERG status assessment on DNA-, mRNA-, and proteinlevels using unique samples from a Swedish biopsy cohort.
• Kaliff, M. , Bohr Mordhorst, L. , Helenius, G. , Karlsson, M. G. & Lillsunde-Larsson, G. Droplet Digital PCR for type-specific detection and quantification of nine different HPV genotypes in cervical carcinomas.
• Nyberg, J. , Helenius, G. , Dahlin, C. , Johansson, C. B. & Omar, O. Effect of radiotherapy on osseointegration : in vivo gene expression and implant stability after single high-dose irradiation.
• Bergengren, L. , Ryen, L. , Flodström, C. , Fadl, H. , Udumyan, R. , Karlsson, M. & Helenius, G. Effectiveness and costs of implemented primary HPV cervical screening : a populationbased cohort study.
• Kaliff, M. , Ekman, M. , Ottestig, E. , Helenius, G. , Bergengren, L. , Karlsson, M. G. & Lillsunde-Larsson, G. Full genotyping and FAM19A4/miR124-2 methylation analysis in high-risk HPV-positive samples from women over 30 years participating in cervical cancer screening in Örebro, Sweden.
• Lillsunde-Larsson, G. , Carlsson, J. , Karlsson, M. G. & Helenius, G. HPV genotyping assays for archival clinical samples : an evaluation study.
• Günaltay, S. , Repsilber, D. , Helenius, G. , Nyhlin, N. , Bohr, J. & Hultgren-Hörnquist, E. Oligoclonal T cell receptor repertoire in colonic biopsies of microscopic and ulcerative colitis patients.
• Kumakech, E. , Berggren, V. , Lillsunde-Larsson, G. , Helenius, G. , Kaliff, M. , Karlsson, M. , Musubika, C. , Kirimunda, S. & et al. Prevalence, genotypes and risk factors for vaccine and non-vaccine types of Human Papillomavirus (HPV) infections among Bivalent HPV-16/18 vaccinated and non-vaccinated young women in Ibanda district Uganda : 5 year follow up study.