Sofia Ramström

Artiklar i tidskrifter

• Tynngård, N. , Alshamari, A. , Sandgren, P. , Kenny, D. , Vasilache, A. M. , Abedi, M. R. & Ramström, S. (2023). High fragmentation in platelet concentrates impacts the activation, procoagulant, and aggregatory capacity of platelets. Platelets, 34 (1).
• Befekadu, R. , Grenegård, M. , Larsson, A. , Christensen, K. & Ramström, S. (2022). Dynamic Changes in Pentraxin-3 and Neprilysin in ST Segment Elevation Myocardial Infarction. Biomedicines, 10 (2).
• Befekadu, R. , Grenegård, M. , Larsson, A. , Christensen, K. & Ramström, S. (2022). Levels of soluble tumor necrosis factor receptor 1 and 2 are associated with survival after ST segment elevation myocardial infarction. Scientific Reports, 12 (1).
• Szanto, T. , Zetterberg, E. , Ramström, S. , Leinøe, E. B. , Holme, P. A. , Antovic, J. P. , Holmström, M. , Onundarson, P. T. & et al. (2022). Platelet function testing: Current practice among clinical centres in Northern Europe. Haemophilia, 28 (4), 642-648.
• Törnudd, M. , Al Ghraoui, M. R. , Wahlgren, S. , Björkman, E. , Berg, S. , Kvitting, J. E. , Alfredsson, J. & Ramström, S. (2022). Quantification of platelet function: a comparative study of venous and arterial blood using a novel flow cytometry protocol. Platelets, 33 (6), 926-934.
• Tynngård, N. , Alshamari, A. , Månsson, F. & Ramström, S. (2022). Variation in activation marker expression within the platelet population - a new parameter for evaluation of platelet flow cytometry data. Platelets, 33 (8), 1113-1118.
• Frelinger, A. L. , Rivera, J. , Connor, D. E. , Freson, K. , Greinacher, A. , Harrison, P. , Kunishima, S. , Lordkipanidzé, M. & et al. (2021). Consensus recommendations on flow cytometry for the assessment of inherited and acquired disorders of platelet number and function: Communication from the ISTH SSC Subcommittee on Platelet Physiology. Journal of Thrombosis and Haemostasis, 19 (12), 3193-3202.
• Bergemalm, D. , Ramström, S. , Kardeby, C. , Hultenby, K. , Göthlin Eremo, A. , Sihlbom, C. , Bergström, J. , Palmblad, J. & et al. (2021). Platelet proteome and function in X-linked thrombocytopenia with thalassemia and in silico comparisons with gray platelet syndrome. Haematologica, 106 (11), 2947-2959.
• Törnudd, M. , Ramström, S. , Kvitting, J. E. , Alfredsson, J. , Pihl, R. & Berg, S. (2021). Protamine stimulates platelet aggregation in vitro with activation of the fibrinogen receptor and alpha-granule release, but impairs secondary activation via ADP and thrombin receptors. Platelets, 32 (1), 90-96.
• Deb, S. , Boknäs, N. , Sjöström, C. , Tharmakulanathan, A. , Lotfi, K. & Ramström, S. (2020). Varying effects of tyrosine kinase inhibitors on platelet function: A need for individualized CML treatment to minimize the risk for hemostatic and thrombotic complications?. Cancer Medicine, 9 (1), 313-323.
• Singh, S. , Damén, T. , Nygren, A. , Shams Hakimi, C. , Ramström, S. , Dellborg, M. , Lindahl, T. L. , Hesse, C. & et al. (2019). Adrenaline Improves Platelet Reactivity in Ticagrelor-Treated Healthy Volunteers. Thrombosis and Haemostasis, 119 (5), 735-743.
• Rajan, M. R. , Sotak, M. , Barrenäs, F. , Shen, T. , Borkowski, K. , Ashton, N. J. , Biörserud, C. , Lindahl, T. L. & et al. (2019). Comparative analysis of obesity-related cardiometabolic and renal biomarkers in human plasma and serum. Scientific Reports, 9 (1).
• Macwan, A. S. , Boknäs, N. , Ntzouni, M. P. , Ramström, S. , Gibbins, J. M. , Faxälv, L. & Lindahl, T. L. (2019). Gradient-dependent inhibition of stimulatory signaling from platelet G protein-coupled receptors. Haematologica, 104 (7).
• Boknäs, N. , Macwan, A. S. , Södergren, A. L. & Ramström, S. (2019). Platelet function testing at low platelet counts: When can you trust your analysis?. Research and Practice in Thrombosis and Haemostasis, 3 (2), 285-290.
• Singh, S. , Malm, C. J. , Ramström, S. , Hesse, C. & Jeppsson, A. (2018). Adrenaline enhances in vitro platelet activation and aggregation in blood samples from ticagrelor-treated patients. Research and Practice in Thrombosis and Haemostasis, 2 (4), 718-725.
• Ramström, S. (2018). Arachidonic acid causes lysis of blood cells and ADP-dependent platelet activation responses in platelet function tests. Platelets, 30 (8), 1001-1007.
• Olsson, A. , Alfredsson, J. , Ramström, S. , Svedjeholm, R. , Kenny, D. , Håkansson, E. , Berglund, J. S. & Berg, S. (2018). Better platelet function, less fibrinolysis and less hemolysis in re-transfused residual pump blood with the Ringer’s chase technique: a randomized pilot study. Perfusion, 33 (3), 185-193.
• Boknäs, N. , Ramström, S. , Faxälv, L. & Lindahl, T. L. (2018). Flow cytometry-based platelet function testing is predictive of symptom burden in a cohort of bleeders. Platelets, 29 (5), 512-519.
• Södergren, A. L. & Ramström, S. (2018). Platelet subpopulations remain despite strong dual agonist stimulation and can be characterised using a novel six-colour flow cytometry protocol. Scientific Reports, 8 (1).
• Centellas, D. S. , Gudlur, S. , Vicente-Carrillo, A. , Ramström, S. & Lindahl, T. L. (2017). A cluster of aspartic residues in the extracellular loop II of PAR 4 is important for thrombin interaction and activation of platelets. Thrombosis Research, 154, 84-92.
• Södergren, A. L. & Ramström, S. (2017). Detection of Lysosomal Exocytosis in Platelets by Flow Cytometry. Methods in Molecular Biology, 1594, 191-203.
• Macwan, A. , Boknäs, N. , Ramström, S. , Berg, S. , Faxälv, L. & Lindahl, T. (2017). Gradient-dependent Modulation of Platelet Stimulatory G-protein Coupled Receptors (GPCR) Signaling. Research and Practice in Thrombosis and Haemostasis, 1 (S1), 1223-1223.
• Ignatova, A. , Nikitin, E. , Tharmakulanathan, A. , Ramström, S. , Poletaev, A. , Polokhov, D. , Fedotov, A. , Seregina, E. & et al. (2017). Platelet Function and Ibrutinib Treatment in Chronic Lymphocytic Leukaemia and Mantle Cell Lymphoma: Effects of Drug and of Disease Itself. Research and Practice in Thrombosis and Haemostasis, 1 (S1), 1344-1344.
• Södergren, A. & Ramström, S. (2017). Platelet reactivity and receptor density in platelets with different MPV. Research and Practice in Thrombosis and Haemostasis, 1 (S1), 1235-1236.
• Lindahl, T. L. , Ramström, S. , Boknas, N. & Faxalv, L. (2016). Caveats in studies of the physiological role of polyphosphates in coagulation. Biochemical Society Transactions, 44 (1), 35-39.
• Deb, S. , Sjöström, C. , Tharmakulanathan, A. , Boknäs, N. , Lotfi, K. & Ramström, S. (2016). Individual variation in hemostatic alterations caused by tyrosine kinase inhibitors: a way to improve personalized cancer therapy?. Thrombosis Research, 140 (Suppl. 1), S196-S197.
• Lindahl, T. L. , Macwan, A. S. & Ramström, S. (2016). Protease-activated receptor 4 is more important than protease-activated receptor 1 for the thrombin-induced procoagulant effect on platelets. Journal of Thrombosis and Haemostasis, 14 (8), 1639-1641.
• Södergren, A. L. , Tynngård, N. , Berlin, G. & Ramström, S. (2016). Responsiveness of platelets during storage studied with flow cytometry - formation of platelet subpopulations and LAMP-1 as new markers for the platelet storage lesion. Vox Sanguinis, 110 (2), 116-125.
• Sodergren, A. L. , Holm, A. B. S. , Ramström, S. , Lindström, E. G. , Grenegård, M. & Öllinger, K. (2016). Thrombin-induced lysosomal exocytosis in human platelets is dependent on secondary activation by ADP and regulated by endothelial-derived substances. Platelets, 27 (1), 86-92.
• Connolly-Andersen, A. , Sundberg, E. , Ahlm, C. , Hultdin, J. , Baudin, M. , Larsson, J. , Dunne, E. , Kenny, D. & et al. (2015). Increased Thrombopoiesis and Platelet Activation in Hantavirus-Infected Patients. Journal of Infectious Diseases, 212 (7), 1061-1069.
• Tynngård, N. , Wallstedt, M. , Södergren, A. L. , Faxälv, L. & Ramström, S. (2015). Platelet adhesion changes during storage studied with a novel method using flow cytometry and protein-coated beads. Platelets, 26 (2), 177-185.
• Lindgren, M. , Meijers, J. C. M. , Biemond, B. J. , Ramström, S. , Lindahl, T. L. , Eriksson, P. , Leitgeb, A. M. , Wahlgren, M. & et al. (2015). Sevuparin: effects on hemostasis of a novel polysaccharide drug derived from heparin. Journal of Thrombosis and Haemostasis, 13 (S2), 369-369.
• Boknas, N. , Faxalv, L. , Lindahl, T. L. & Ramström, S. (2014). Contact activation: important to consider when measuring the contribution of tissue factor-bearing microparticles to thrombin generation using phospholipid-containing reagents. Journal of Thrombosis and Haemostasis, 12 (4), 515-518.
• Boknäs, N. , Faxälv, L. , Ström, J. O. , Tengvall, P. , Theodorsson, E. , Ramström, S. & Lindahl, T. L. (2014). Platelets do not generate activated factor XII: how inappropriate experimental models have led to misleading conclusions. Blood, 124 (10), 1692-1694.
• Peng, X. , Ramström, S. , Kurz, T. , Grenegård, M. & Segelmark, M. (2014). The neutrophil serine protease PR3 induces shape change of platelets via the Rho/Rho kinase and Ca2+ signaling pathways. Thrombosis Research, 134 (2), 418-425.
• Boknäs, N. , Faxälv, L. , Sanchez Cenellas, D. , Wallstedt, M. , Ramström, S. , Grenegård, M. & Lindahl, T. L. (2014). Thrombin-induced platelet activation via PAR4: pivotal role for exosite II. Thrombosis and Haemostasis, 112 (3), 558-565.
• Lopez, A. , Kenny, D. , Basabe-Desmonts, L. , Ramström, S. , Jose, B. & Somers, M. (2013). A novel platelet assay that measures the effect of clopidogrel in vivo. Journal of Thrombosis and Haemostasis, 11 (S2), 73-73.
• Lopez-Alonso, A. , Jose, B. , Somers, M. , Egan, K. , Foley, D. P. , Ricco, A. J. , Ramström, S. , Basabe-Desmonts, L. & et al. (2013). Individual Platelet Adhesion Assay: Measuring Platelet Function and Antiplatelet Therapies in Whole Blood via Digital Quantification of Cell Adhesion. Analytical Chemistry, 85 (13), 6497-6504.
• Faxälv, L. , Boknäs, N. , Ström, J. O. , Tengvall, P. , Theodorsson, E. , Ramström, S. & Lindahl, T. L. (2013). Putting polyphosphates to the test: evidence against platelet-induced activation of factor XII. Blood, 122 (23), 3818-3824.
• Södergren, A. L. , Ollinger, K. & Ramström, S. (2013). Subdivision according to size is necessary for correct interpretation of data regarding platelet expression of active GPIIb/IIIa and phosphatidylserine. Journal of Thrombosis and Haemostasis, 11 (S1), 498-498.
• Boknäs, N. , Faxälv, L. , Ramström, S. & Lindahl, T. (2013). Thrombin generation in plasma measured with a commercial reagent for the detection of microparticle-derived tissue factor is heavily influenced by contact activation. Journal of Thrombosis and Haemostasis, 11 (S1), 401-402.
• Tynngård, N. , Ramström, S. & Berlin, G. (2012). Adhesion Capacity of Platelets During Storage: Evaluation of a Flow Cytometric Adhesion Assay. Transfusion, 52 (S3), 70A-70A.
• Nylander, M. , Osman, A. , Ramström, S. , Aklint, E. , Larsson, A. & Lindahl, T. L. (2012). The role of thrombin receptors PAR1 and PAR4 for PAI-1 storage, synthesis and secretion by human platelets. Thrombosis Research, 129 (4), E51-E58.
• Börgeson, E. , Lönn, J. , Bergström, I. , Brodin, V. P. , Ramström, S. , Nayeri, F. , Särndahl, E. & Bengtsson, T. (2011). Lipoxin A(4) inhibits porphyromonas gingivalis-induced aggregation and reactive oxygen species production by modulating neutrophil-platelet interaction and CD11b expression. Infection and Immunity, 79 (4), 1489-1497.
• Ramström, S. , O'Neill, S. , Dunne, E. & Kenny, D. (2010). Annexin V binding to platelets is agonist, time and temperature dependent. Platelets, 21 (4), 289-296.
• Basabe-Desmonts, L. , Ramström, S. , Meade, G. , O'Neill, S. , Riaz, A. , Lee, L. P. , Ricco, A. J. & Kenny, D. (2010). Single-Step Separation of Platelets from Whole Blood Coupled with Digital Quantification by Interfacial Platelet Cytometry (iPC). Langmuir, 26 (18), 14700-14706.

Artiklar, forskningsöversikter

• Ramström, S. , Södergren, A. L. , Tynngård, N. & Lindahl, T. L. (2016). Platelet Function Determined by Flow Cytometry: New Perspectives?. Seminars in Thrombosis and Hemostasis, 42 (3), 268-281.
• Tynngård, N. , Lindahl, T. L. & Ramström, S. (2015). Assays of different aspects of haemostasis: what do they measure?. Thrombosis Journal, 13.

Konferensbidrag

• Södergren, A. & Ramström, S. (2016). Platelet subpopulations : do they exist? .  Konferensbidrag vid 3rd EUPLAN Conference, Bad Homburg, Germany, 21-23 September, 2016.
• Sánchez Centellas, D. , Vicente-Carrillo, A. , Ramström, S. & Lindahl, T. (2014). Advances on yeast methods to study recombinant human PAR4.  Konferensbidrag vid 2nd EUPLAN (European Platelet Network) Conference, Strasbourg, France, September 24-26.
• Ramström, S. (2014). Experiences with “spontaneous” contact activation and Microvesicles in Thrombin generation.: Invited presentation at a round table discussion, “Pre-analytical problems and solutions for assays sensitive to contact activation“.  Konferensbidrag vid ECAT meeting, Leiden, Netherlands, November 2013.
• Deb, S. & Ramström, S. (2014). Intracellular signaling in platelet sub-populations: a flow cytometry-based approach.  Konferensbidrag vid 47th Nordic Coagulation Meeting, Visby, Sweden, September 9-12, 2014.
• Andraos, R. , Södergren, A. , Öllinger, K. & Ramström, S. (2014). Reactive oxygen species enhance generation of subpopulations of procoagulant platelets.  Konferensbidrag vid 2nd EUPLAN (European Platelet Network) Conference, Le Bischenberg, France, September 24-26, 2014.
• Andraos, R. , Södergren, A. , Öllinger, K. & Ramström, S. (2014). Reactive oxygen species enhance generation of subpopulations of procoagulant platelets.  Konferensbidrag vid 47th Nordic Coagulation Meeting, Visby, Sweden, September 9-12, 2014.
• Batakis, P. , Lopez-Alonso, A. , Claesson, K. , Kenny, D. , Basabe-Desmonts, L. & Ramström, S. (2013). Microcontact printing as a tool to study platelet adhesion.  Konferensbidrag vid 46th Nordic Coagulation Meeting, Tromsö, Norway, June 6-8, 2013.
• Boknäs, N. , Faxälv, L. & Ramström, S. (2013). Phospholipid-containing reagents for the detection of tissue factor on microparticles by thrombin generation cause analytical errors by amplifying the contact activation pathway.  Konferensbidrag vid Eurothrombosis Summit, Uppsala, Sweden, October 3-5, 2013.
• Lopez-Alonso, A. , Basabe-Desmonts, L. , Ramström, S. , Jose, B. , Sommers, M. , Redahan, L. , Conlon, P. & Kenny, D. (2012). A novel platelet function assay that identifies bleeding risk and quantifies anti-platelet drug effect.  Konferensbidrag vid BSHT/13th UK Platelet Group meeting, Bath, UK, October 18-19, 2012.
• Södergren, A. , Tynngård, N. & Ramström, S. (2012). Changes in platelet function during storage : evaluation of a flow cytometry method for studies of platelet adhesion and activation.  Konferensbidrag vid BSHT/13th UK Platelet Group meeting, Bath, UK, October 18-19, 2012.
• Södergren, A. , Tynngård, N. & Ramström, S. (2012). Changes in platelet function during storage: evaluation of a flow cytometry method for studies of platelet adhesion and activation.  Konferensbidrag vid EUPLAN (European Platelet Network) Conference, Maastricht, the Netherlands, September 19-21, 2012.
• Faxälv, L. , Ramström, S. , Soutukorva, K. , Tengvall, P. & Lindahl, T. (2012). Coagulation factor XII is not activated by platelets but facilitates platelet-driven propagation of coagulation .  Konferensbidrag vid EUPLAN (European Platelet Network) Conference, Maastricht, the Netherlands, September 19-21, 2012.
• Faxälv, L. , Wallstedt, M. & Ramström, S. (2011). A flow cytometric method to study platelet adhesion to protein-coated polystyrene beads.  Konferensbidrag vid 13th UK Platelet Group Meeting, Cardiff, September 8 – 9th, 2011.
• Basabe-Desmonts, L. , Ramström, S. , Lopez-Alonso, A. , Somers, M. , Ricco, A. J. & Kenny, D. (2010). Disposable bioanalytical microdevice for monitoring the effect of anti-platelet drugs. I:  14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. Konferensbidrag vid 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010, Groningen, The Netherlands, 3 - 7 October, 2010. (ss. 1388-1390).

Manuskript

• Befekadu, R. , Grenegård, M. , Larsson, A. , Christensen, K. , Nilsson, B. & Ramström, S. Activation of the lectin complement pathway during and after ST segment elevation myocardial infarction.
• Lindkvist, M. , Ljungberg, L. U. , Fälker, K. , Ramström, S. , Kardeby, C. , Sirsjö, A. & Grenegård, M. IL-6 trans-signalling inhibits micro- and macro-aggregation induced by epinephrine in human platelets.