Cardiovascular Research Centre (CVRC)
Cardiovascular diseases such as arrhythmias, myocardial infarction and heart failure are the most common cause of death in the industrialised Western world and the cost for the society and the health care system to treat cardiovascular diseases is tremendous. It is of main importance to strengthen research activities to identify new mechanisms, risk factors and new target principles for more effective diagnosis, treatment and prevention of cardiovascular diseases.
About
Environment information
Contact
Research domains
- Medicine
Areas of research
- Biomedicine
- Cirkulation
- Haemostasis
- Immunology
- Inflammation
- Cardiology
- Medicine
- Microbiology
The Cardiovascular Research Centre (CVRC) research environment is a network of approximately 40 members at Örebro University and Örebro University Hospital/Region Örebro County working with basic, translational and clinical research to identify new mechanisms, risk factors and new target principles for more effective diagnosis, treatment and prevention of cardiovascular diseases. The CVRC was founded in 2014 and the overall strategy is to support internal and external academic and industrial research collaboration and to contribute to a successful and high-quality third cycle education in the field of cardiovascular research. The CVRC has been ranked as a strong research environment by external evaluators.
Researchers
- Torbjörn Bengtsson
- Cecilia Bergh
- Dick Delbro
- Karin H Franzén
- Ole Fröbert
- Knut Fälker
- Magnus Grenegård
- Hans Hjelmqvist
- Tal Hörer
- Hazem Khalaf
- Ashok Kumawat
- Liza Ljungberg
- Mulugeta Melkie Zegeye
- Kristofer Nilsson
- Eva Oskarsson
- Eleonor Palm
- Geena Paramel
- Sofia Ramström
- Dirk Repsilber
- Karthik Selvaraj
- Allan Sirsjö
- Maria Åström
- Isabelle Grafver, PhD student
- David McGreevy, PhD student
- Abubakr Omer, PhD student
- Anna Stene Hurtsen, PhD student
- Maria Wikström, PhD student
- Emanuel Wiman, PhD student
Research teams
- Endovascular and hybrid resuscitation, bleeding management and postoperative care: Innovative methods and pathophysiology in life-threatening conditions
- Functional Bioinformatics
- Ikaria Healthy Ageing
- Lifestyle and Cardiovascular Disease
- Molecular cardiovascular research
- Novel antibacterial agents and bacterial sensors in the fight against infections
- Platelet and thrombosis research
Research projects
- Bacteriocins in prevention and treatment of infections
- Combinations of arterial and venous endovascular balloon occlusion-providing a new management for traumatic retrohepatic liver- and vena caval injuries?
- Connection between primary and secondary hemostasis
- Cross-talk between platelets and the vessel wall
- Genetic variations in genes associated with inflammation and predisposition for altered biomarker profiles
- Gut microbe-derived diet metabolite and immunomodulatory responses in atherosclerosis
- Inflammation and lipids in vascular disease
- Interactions between microbiome, diet metabolite and inflammation in peripheral arterial disease
- Interleukin-6 as a therapeutic target for atherosclerosis
- Intestinal macrophages in pathogenesis of inflammatory bowel disease
- Lifestyle, Biomarkers, and Atherosclerosis (LBA) Study
- Link between primary hemostasis and inflammation
- Network medicine and systems biological approaches to modeling inflammation
- Nitric oxide based treatment of critical illness
- Plastic antibodies and nanoplasmonic sensors in targeting risk markers of periodontitis and systemic disorders
- Platelet function in cardiothoracic surgery and cardiology
- Platelet function in transfusion medicine
- Platelet proteome and function in hematological diseases
- Prevalence and prognostic implications of cardiac injury in patients with influenza-like illness
- Role of CARD8 for inflammation in vascular cells
- Role of NLRP3 inflammasome and interleukin-1 (IL-1) in cardiovascular disease
- Role of zinc finger proteins in cardiovascular diseases and cancer
News & Media
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Student Jan from Germany contributing to research on cardiovascular disease: “Have gained new perspectives”
Since early November, biomedical student Jan Bobrowski from Germany have worked alongside researchers at Örebro University’s Cardiovascular Research Centre to identify new drugs to treat cardiovascular disease.
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Investigates the role of cells in the development of heart diseases
High blood pressure and diabetes damage cells in our blood vessels, which can lead to heart attack and stroke. Can the blocking of two proteins prevent this? That is something the Örebro researcher Mulugeta Zegeye is intending to find out.
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Örebro researchers show how a peptide can render antibiotics effective again – at doses 100 times lower than usual
A peptide renders older antibiotics effective again at doses 100 times lower than the common dosage, as shown by research from Örebro University. Lower doses of antibiotics in turn reduces the risk of further development of antibiotic resistance.
Source of external research funding - current and previous
